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ClinicalTrials.gov public records Last synced Oct 23, 2026, 8:41 PM EDT

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Showing 1–24 of 59 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Aneuploidy Clear all
Recruiting No phase listed Observational

Specimen Collection From Pregnant Women at Increased Risk for Fetal Aneuploidy

NCT01429389
View directory record Official record
Conditions
Down Syndrome, Fetal Aneuploidy
Interventions
Not listed
Lead sponsor
Sequenom, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2028
U.S. locations
12
States / cities
Birmingham, Alabama • Los Angeles, California • San Diego, California + 6 more
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 23, 2026, 8:41 PM EDT
Completed No phase listed Observational

MatErnal BLood IS Source to Accurately Diagnose Fetal Aneuploidy

NCT01122524
View directory record Official record
Conditions
Pregnant Women, Prenatal Care
Interventions
Not listed
Lead sponsor
Verinata Health, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
10,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
11
States / cities
Los Angeles, California • San Francisco, California • Fort Collins, Colorado + 8 more
Source: ClinicalTrials.gov public record
Updated Oct 10, 2011 · Synced Oct 23, 2026, 8:41 PM EDT
Active, not recruiting Not applicable Interventional

To Investigate if the Harvester® Improves Sperm Motility and Blastocyst Utilization (the Percent of Fertilized Eggs That Develop to the Point That They Are Able to be Transferred) in IVF Cycles.

NCT07369362
View directory record Official record
Conditions
Infertility, Male Infertility, InVitro Fertilization, Aneuploidy Rate, Euploidy Rate
Interventions
microfludics semen processing device
Device
Lead sponsor
MotilityCount aps
Industry
Eligibility
21 Years to 45 Years
Enrollment
1,600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Oct 23, 2026, 8:41 PM EDT
Completed No phase listed Observational

Multi-center Study to Validate niPGT-A

NCT03520933
View directory record Official record
Conditions
Aneuploidy, Chromosome Abnormality, Infertility
Interventions
PGT-A, niPGT-A
Diagnostic Test
Lead sponsor
Igenomix
Industry
Eligibility
20 Years to 44 Years · Female only
Enrollment
2,586 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
3
States / cities
San Diego, California • Boston, Massachusetts • Arlington, Washington
Source: ClinicalTrials.gov public record
Updated May 24, 2023 · Synced Oct 23, 2026, 8:41 PM EDT
Terminated No phase listed Observational

Clinical Performance of the MaterniT21 PLUS LDT in Multiple Gestation Pregnancies

NCT02226315
View directory record Official record
Conditions
Down Syndrome, Edwards Syndrome, Patau Syndrome, Turner Syndrome
Interventions
Not listed
Lead sponsor
Sequenom, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 17, 2015 · Synced Oct 23, 2026, 8:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Aneuploidy Rates in Advanced Maternal Age Patients Supplemented With Coenzyme Q10 (CoQ10) Versus Those That Are Not: a Pilot Study

NCT02119117
View directory record Official record
Conditions
Mitochondrial DNA, Aneuploidy
Interventions
CoQ10, Placebo
Dietary Supplement
Lead sponsor
Reproductive Endocrinology Associates of Charlotte
Other
Eligibility
36 Years to 42 Years · Female only
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated May 4, 2018 · Synced Oct 23, 2026, 8:41 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Non-Invasive Chromosomal Evaluation of Trisomy Study

NCT02201862
View directory record Official record
Conditions
Aneuploidy, Trisomy 21, Trisomy 18, Trisomy 13, Down Syndrome
Interventions
Not listed
Lead sponsor
Cindy Cisneros
Industry
Eligibility
18 Years to 60 Years · Female only
Enrollment
2,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
3
States / cities
San Diego, California • Oaks, Pennsylvania • Chattanooga, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 30, 2020 · Synced Oct 23, 2026, 8:41 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

National Prevalence and Impact of Noninvasive Prenatal Testing

NCT02284399
View directory record Official record
Conditions
Aneuploidy
Interventions
non-invasive prenatal testing
Other
Lead sponsor
Obstetrix Medical Group
Industry
Eligibility
18 Years to 60 Years · Female only
Enrollment
4,488 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
7
States / cities
Phoenix, Arizona • Long Beach, California • San Jose, California + 4 more
Source: ClinicalTrials.gov public record
Updated Jun 19, 2019 · Synced Oct 23, 2026, 8:41 PM EDT
Completed Phase 4 Interventional Results available

Body Composition in Infants With Klinefelter Syndrome and Effects of Testosterone Treatment

NCT02408445
View directory record Official record
Conditions
Klinefelter Syndrome
Interventions
testosterone cypionate 200mg/ml
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
42 Days to 108 Days · Male only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 15, 2020 · Synced Oct 23, 2026, 8:41 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Down Syndrome - Comparison of Screening Methods in the 1st and 2nd Trimesters

NCT00006445
View directory record Official record
Conditions
Down Syndrome, Chromosome Abnormalities
Interventions
Ultrasound, Serum screen
Procedure
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
16 Years to 45 Years · Female only
Enrollment
38,000 participants
Healthy volunteers
Accepts healthy volunteers
U.S. locations
10
States / cities
Denver, Colorado • Boston, Massachusetts • Royal Oak, Michigan + 6 more
Source: ClinicalTrials.gov public record
Updated Feb 22, 2007 · Synced Oct 23, 2026, 8:41 PM EDT
Completed No phase listed Observational

Cardiometabolic Profiles of Boys With Klinefelter Syndrome

NCT02723305
View directory record Official record
Conditions
Klinefelter Syndrome, 47,XXY, Sex Chromosome Aneuploidy, XXY Syndrome
Interventions
No intervention
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
12 Years to 17 Years · Male only
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 8, 2022 · Synced Oct 23, 2026, 8:41 PM EDT
Completed No phase listed Observational

Mitochondrial Dysfunction in Phelan-McDermid Syndrome

NCT02000167
View directory record Official record
Conditions
Phelan-McDermid Syndrome
Interventions
Not listed
Lead sponsor
University of Arkansas
Other
Eligibility
1 Year to 21 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Aug 5, 2021 · Synced Oct 23, 2026, 8:41 PM EDT
Completed No phase listed Observational

Clinical Evaluation of the SEQureDx Trisomy Test in Low Risk Pregnancies

NCT01597063
View directory record Official record
Conditions
Aneuploidy, Down Syndrome, Noninvasive Prenatal Screening
Interventions
SEQureDx Trisomy Test
Device
Lead sponsor
Sequenom, Inc.
Industry
Eligibility
18 Years to 34 Years · Female only
Enrollment
3,333 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
27
States / cities
Mobile, Alabama • Chandler, Arizona • Phoenix, Arizona + 22 more
Source: ClinicalTrials.gov public record
Updated Apr 20, 2016 · Synced Oct 23, 2026, 8:41 PM EDT
Not listed No phase listed Observational

Non-Invasive Screening for Fetal Aneuploidy

NCT02317965
View directory record Official record
Conditions
Down Syndrome, Edwards Syndrome
Interventions
Maternal Blood Draw
Other
Lead sponsor
Progenity, Inc.
Industry
Eligibility
18 Years to 54 Years · Female only
Enrollment
340 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
10
States / cities
Campbell, California • Long Beach, California • Denver, Colorado + 6 more
Source: ClinicalTrials.gov public record
Updated Aug 28, 2018 · Synced Oct 23, 2026, 8:41 PM EDT
Completed Not applicable Interventional

Next Generation Sequencing Screening for Embryonic Ploidy Status

NCT02032264
View directory record Official record
Conditions
Infertility
Interventions
Comprehensive Chromosome Screening, Morphologically Best
Other
Lead sponsor
Reproductive Medicine Associates of New Jersey
Other
Eligibility
18 Years to 42 Years · Female only
Enrollment
309 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Basking Ridge, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 17, 2017 · Synced Oct 23, 2026, 8:41 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Evaluating the Status of Complex Aneuploidy to Locate Additional Transferrable Embryos

NCT07227116
View directory record Official record
Conditions
Complex Aneuploidy, Chaotic Aneuploidy
Interventions
Not listed
Lead sponsor
Shady Grove Fertility Reproductive Science Center
Other
Eligibility
Not listed
Enrollment
280 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
10
States / cities
Margate, Florida • Atlanta, Georgia • Highland Park, Illinois + 7 more
Source: ClinicalTrials.gov public record
Updated Nov 12, 2025 · Synced Oct 23, 2026, 8:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Screening of Low Responders for Aneuploidy to Improve Reproductive Efficiency

NCT01977144
View directory record Official record
Conditions
Infertility
Interventions
Comprehensive Chromosomal Screening
Other
Lead sponsor
Reproductive Medicine Associates of New Jersey
Other
Eligibility
18 Years to 43 Years · Female only
Enrollment
206 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2020
U.S. locations
1
States / cities
Basking Ridge, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 14, 2022 · Synced Oct 23, 2026, 8:41 PM EDT
Completed No phase listed Observational

Outcome of Embryos Transferred After Initial Chaotic Results on PGT-A

NCT06373237
View directory record Official record
Conditions
Infertility
Interventions
Not listed
Lead sponsor
Inception Fertility Research Institute, LLC
Industry
Eligibility
Female only
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 20, 2025 · Synced Oct 23, 2026, 8:41 PM EDT
Recruiting No phase listed Observational

Non-Euploid Embryo Transfer (NEET) Registry

NCT07036536
View directory record Official record
Conditions
Infertility, Mosaicism, Aneuploidy
Interventions
Not listed
Lead sponsor
Inception Fertility Research Institute, LLC
Industry
Eligibility
Female only
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2030
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 14, 2026 · Synced Oct 23, 2026, 8:41 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Prenatal Computer-Aided Genetics Education Module

NCT03449225
View directory record Official record
Conditions
Autosomal Recessive Disorder, Aneuploidy
Interventions
Computer-Aided Genetic Education Module
Other
Lead sponsor
Wayne State University
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated May 2, 2019 · Synced Oct 23, 2026, 8:41 PM EDT
Completed No phase listed Observational

VAlidation of a Lower Cost aneUploidy scrEen

NCT03087357
View directory record Official record
Conditions
Down Syndrome, Trisomy 18, Trisomy 13
Interventions
SmartNIPT
Other
Lead sponsor
Women and Infants Hospital of Rhode Island
Other
Eligibility
18 Years and older · Female only
Enrollment
2,443 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
13
States / cities
Los Angeles, California • Aurora, Colorado • Bridgeport, Connecticut + 9 more
Source: ClinicalTrials.gov public record
Updated Sep 22, 2022 · Synced Oct 23, 2026, 8:41 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

GEM: Impact of a Video Education Tool on Decisional Conflict Among Prenatal Patients

NCT06771453
View directory record Official record
Conditions
Aneuploidy, Genetic Counseling, Informed Consent, Decisional Conflict
Interventions
Video Educational Tool Regarding Prenatal Genetics
Other
Lead sponsor
Women and Infants Hospital of Rhode Island
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 18, 2025 · Synced Oct 23, 2026, 8:41 PM EDT
Terminated Not applicable Interventional

Clinical Study of PGT-A Versus PGT-A+ERA

NCT03530254
View directory record Official record
Conditions
Infertility of Uterine Origin
Interventions
PGT-A, ERA Test
Diagnostic Test
Lead sponsor
Igenomix
Industry
Eligibility
Female only
Enrollment
368 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
2
States / cities
Newport Beach, California • Reading, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 4, 2022 · Synced Oct 23, 2026, 8:41 PM EDT
Completed No phase listed Observational

Clinical Evaluation of the SEQureDx T21 Test In High Risk Pregnancies

NCT01555346
View directory record Official record
Conditions
Down Syndrome, Fetal Aneuploidy
Interventions
Not listed
Lead sponsor
Sequenom, Inc.
Industry
Eligibility
18 Years to 60 Years · Female only
Enrollment
3,062 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
27
States / cities
Mobile, Alabama • Tucson, Arizona • Campbell, California + 24 more
Source: ClinicalTrials.gov public record
Updated Apr 20, 2016 · Synced Oct 23, 2026, 8:41 PM EDT