Evaluating the Status of Complex Aneuploidy to Locate Additional Transferrable Embryos
Public ClinicalTrials.gov record NCT07227116. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
ESCALATE: Evaluating the Status of Complex Aneuploidy to Locate Additional Transferrable Embryos
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study aims to evaluate the reproductive potential of embryos classified as "complex aneuploid" (involving three or more abnormal chromosomes) or "chaotic" (six or more abnormal chromosomes) through preimplantation genetic testing for aneuploidy (PGT-A). Specifically, we seek to determine whether embryos initially reported as having multiple chromosomal abnormalities might still have the potential for normal chromosomal composition, the opportunity for transfer, and ultimately, the potential to achieve a live birth through re-biopsy and reanalysis. Key Information: This portion of the study seeks your consent for the re-biopsy and genetic reanalysis of the embryos only. It does not yet include consent for potential future transfer. Participation remains completely voluntary, and your decision will not affect your current or future care. We deeply appreciate your support and commitment to advancing fertility research.
Study identification
- NCT ID
- NCT07227116
- Recruitment status
- Recruiting
- Study type
- Observational
- Phase
- Not listed
- Enrollment
- 280 participants
Conditions and interventions
Conditions
Interventions
Not listed
Eligibility (public fields only)
- Age range
- Not listed
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 31, 2025
- Primary completion
- Mar 31, 2026
- Completion
- May 31, 2026
- Last update posted
- Nov 11, 2025
2025 – 2026
United States locations
- U.S. sites
- 10
- U.S. states
- 7
- U.S. cities
- 10
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| IVF Florida Reproductive Associates | Margate | Florida | 33063 | Recruiting |
| Shady Grove Fertility | Atlanta | Georgia | 30342 | Recruiting |
| Fertility Center of Illinois | Highland Park | Illinois | 60035 | Recruiting |
| Shady Grove Fertility | Rockville | Maryland | 20850 | Recruiting |
| Shady Grove Fertility | Towson | Maryland | 33607 | Recruiting |
| Shady Grove Fertility | Cary | North Carolina | 27519 | Recruiting |
| Shady Grove Fertility | Chesterbrook | Pennsylvania | 19087 | Recruiting |
| Shady Grove Fertility | Fairfax | Virginia | 22031 | Recruiting |
| Shady Grove Fertility | Norfolk | Virginia | 23507 | Recruiting |
| Shady Grove Fertility | Richmond | Virginia | 23235 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07227116, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 11, 2025 · Synced Sep 3, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07227116 live on ClinicalTrials.gov.