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ClinicalTrials.gov public records Last synced Oct 2, 2026, 5:21 AM EDT

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Showing 49–72 of 144 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Aneurysm, Intracranial Clear all
Recruiting Not applicable Interventional

Evaluation of Flow Diverter Technology Device for Intracranial Aneurysm (SHIELD)

NCT06793059
View directory record Official record
Conditions
Aneurysm
Interventions
SHIELD
Device
Lead sponsor
Jacobs institute
Other
Eligibility
22 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Oct 2, 2026, 5:21 AM EDT
Recruiting Phase 4 Interventional

Intranasal Sphenopalatine Ganglion Blockade for Headaches Following Aneurysmal Subarachnoid Hemorrhage

NCT07116408
View directory record Official record
Conditions
Aneurysmal Subarachnoid Hemorrhage (aSAH), Headache
Interventions
Lidocaine (drug), Tx 360
Drug · Device
Lead sponsor
Wright State University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Dayton, Ohio
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Oct 2, 2026, 5:21 AM EDT
Withdrawn Not applicable Interventional

Supraphysiologic Insulin to Improve Outcomes After Surgical Treatment of Unruptured Cerebral Aneurysms

NCT00615381
View directory record Official record
Conditions
Intracranial Aneurysm
Interventions
Insulin
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 23, 2015 · Synced Oct 2, 2026, 5:21 AM EDT
Terminated Phase 2 Interventional Results available

Safety and Efficacy Study of Clevidipine to Control Hypertension in Patients Admitted With Aneurysmal Subarachnoid Hemorrhage

NCT00978822
View directory record Official record
Conditions
Subarachnoid Hemorrhage, Hypertension
Interventions
Clevidipine butyrate injectable emulsion
Drug
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years to 80 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 2, 2023 · Synced Oct 2, 2026, 5:21 AM EDT
Completed Phase 2 Interventional

Balloon Prophylaxis of Aneurysmal Vasospasm

NCT00282893
View directory record Official record
Conditions
Aneurysm, Vasospasm
Interventions
transluminal ballooning, currently existing therapies for the treatment of vasospasm
Procedure · Other
Lead sponsor
University of California, Davis
Other
Eligibility
17 Years and older
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2006
U.S. locations
3
States / cities
Sacramento, California • Nashville, Tennessee • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 15, 2017 · Synced Oct 2, 2026, 5:21 AM EDT
Not yet recruiting Phase 4 Interventional

Lumbar Drain With Intrathecal Nicardipine in Aneurysmal Subarachnoid Hemorrhage

NCT07246629
View directory record Official record
Conditions
Subarachnoid Hemorrhage
Interventions
Normal Saline, Nicardipine
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
214 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
1
States / cities
Park Ridge, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 1, 2026 · Synced Oct 2, 2026, 5:21 AM EDT
Terminated No phase listed Observational

CARE: A Prospective Multicenter Case Study to Assess Radiation Exposure in Patients Treated With the Penumbra Coil 400

NCT02122133
View directory record Official record
Conditions
Intracranial Aneurysms
Interventions
PC 400
Device
Lead sponsor
Penumbra Inc.
Industry
Eligibility
Not listed
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Bellevue, Washington
Source: ClinicalTrials.gov public record
Updated Apr 12, 2019 · Synced Oct 2, 2026, 5:21 AM EDT
Not listed No phase listed Observational

TARGET Intracranial Aneurysm Coiling Registry

NCT01748903
View directory record Official record
Conditions
Intracranial Aneurysms
Interventions
Target 360°, 2D Coils, Nano Coils
Device
Lead sponsor
Mercy Health Ohio
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
9
States / cities
Phoenix, Arizona • Tallahassee, Florida • Joliet, Illinois + 6 more
Source: ClinicalTrials.gov public record
Updated Jul 24, 2018 · Synced Oct 2, 2026, 5:21 AM EDT
Active, not recruiting Not applicable Interventional

MicroVention, Inc. Flow Re-Direction Endoluminal Device X (FRED™ X™) Post-Approval Study

NCT05409989
View directory record Official record
Conditions
Intracranial Aneurysm
Interventions
FRED™ X™
Device
Lead sponsor
Microvention-Terumo, Inc.
Industry
Eligibility
22 Years to 75 Years
Enrollment
154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2030
U.S. locations
23
States / cities
Hollywood, Florida • Orlando, Florida • Honolulu, Hawaii + 18 more
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced Oct 2, 2026, 5:21 AM EDT
Terminated Not applicable Interventional Results available

Study to Evaluate the Safety and Effectiveness of the CODMAN ENTERPRISE® Vascular Reconstruction Device

NCT02532517
View directory record Official record
Conditions
Intracranial Aneurysm
Interventions
CODMAN ENTERPRISE® Vascular Reconstruction Device and Delivery System
Device
Lead sponsor
Cerenovus, Part of DePuy Synthes Products, Inc.
Industry
Eligibility
21 Years to 70 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
11
States / cities
Englewood, Colorado • Gainesville, Florida • Jacksonville, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Oct 23, 2020 · Synced Oct 2, 2026, 5:21 AM EDT
Completed No phase listed Observational Results available

Study to Evaluate Cerebral AneurysmFlow Results in Occlusion

NCT03663257
View directory record Official record
Conditions
Intracranial Aneurysm
Interventions
AneurysmFlow
Device
Lead sponsor
Philips Clinical & Medical Affairs Global
Industry
Eligibility
18 Years and older
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
2
States / cities
Jacksonville, Florida • Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 26, 2025 · Synced Oct 2, 2026, 5:21 AM EDT
Completed Not applicable Interventional Results available

Assessment of the Embolization of Neurovascular Lesions Using the Penumbra Smart Coil

NCT02729740
View directory record Official record
Conditions
Intracranial Aneurysm
Interventions
Penumbra Smart Coil, Penumbra Coil 400TM (PC400), Penumbra Occlusion DeviceTM(POD)
Device
Lead sponsor
Penumbra Inc.
Industry
Eligibility
Not listed
Enrollment
995 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
71
States / cities
Dothan, Alabama • Mesa, Arizona • Phoenix, Arizona + 62 more
Source: ClinicalTrials.gov public record
Updated Mar 1, 2021 · Synced Oct 2, 2026, 5:21 AM EDT
Completed Not applicable Interventional Results available

The Penumbra Liberty Trial: Safety and Effectiveness in the Treatment of Wide-Neck Intracranial Aneurysms

NCT01636453
View directory record Official record
Conditions
Wide-neck, Saccular Intracranial Aneurysms
Interventions
Stent assisted coiling with the Liberty Stent
Device
Lead sponsor
Penumbra Inc.
Industry
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
3
States / cities
Denver, Colorado • Chicago, Illinois • Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Aug 23, 2018 · Synced Oct 2, 2026, 5:21 AM EDT
Completed No phase listed Observational

Beacon Tip Sizing Catheter and Slip-Cath Beacon Tip Catheter Study

NCT06986954
View directory record Official record
Conditions
Stenosis, Bleed Intracranial, Stroke, TIA, Vascular Malformation, Pseudoaneurysm
Interventions
Beacon Tip Catheters
Device
Lead sponsor
Cook Research Incorporated
Industry
Eligibility
Not listed
Enrollment
816 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Darien, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Oct 2, 2026, 5:21 AM EDT
Active, not recruiting Phase 4 Interventional

US IDE Study of the Contour NEurovasCular System™ for IntraCranial Aneurysm Repair

NCT04852783
View directory record Official record
Conditions
Aneurysm, Intracranial
Interventions
Contour Neurovascular System
Device
Lead sponsor
Cerus Endovascular, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2030
U.S. locations
20
States / cities
Englewood, Colorado • Jacksonville, Florida • Chicago, Illinois + 16 more
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Oct 2, 2026, 5:21 AM EDT
Recruiting No phase listed Observational

Optima Coil Performance in The Interventional Management of Intracranial Aneurysms Registry

NCT06282939
View directory record Official record
Conditions
Intracranial Aneurysm
Interventions
OPTIMA and OPTIMAX Coils manufactured by Balt USA
Device
Lead sponsor
HCA Healthcare Research Institute
Other
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Plano, Texas
Source: ClinicalTrials.gov public record
Updated Feb 28, 2024 · Synced Oct 2, 2026, 5:21 AM EDT
Completed No phase listed Observational

Optical Coherence Tomography Imaging of Post Coil Aneurysm Healing.

NCT00556309
View directory record Official record
Conditions
Cerebral Aneurysm
Interventions
Optical Coherence Tomography
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
2
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Oct 20, 2022 · Synced Oct 2, 2026, 5:21 AM EDT
Terminated Not applicable Interventional

EvaLuate EndoVascular Treatment of Acutely Ruptured Shallow Intradural Aneurysms With the Pipeline™ Flex Embolization Device With Shield TEchnology™ (ELEVATE)

NCT04391803
View directory record Official record
Conditions
Intracranial Aneurysm, Ruptured Aneurysm
Interventions
Pipeline™ Flex Embolization Device with Shield Technology™
Device
Lead sponsor
Medtronic Neurovascular Clinical Affairs
Industry
Eligibility
22 Years to 80 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
7
States / cities
New Haven, Connecticut • Marietta, Georgia • Chicago, Illinois + 4 more
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Oct 2, 2026, 5:21 AM EDT
Active, not recruiting Not applicable Interventional

Kaneka iED Coil System for the Treatment of Wide Necked Ruptured and Unruptured Intracranial Aneurysms

NCT05636124
View directory record Official record
Conditions
Intracranial Aneurysms, Wide Neck Intracranial Aneurysms
Interventions
Kaneka i-ED coil
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
5
States / cities
Danville, California • Jacksonville, Florida • Tampa, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 12, 2026 · Synced Oct 2, 2026, 5:21 AM EDT
Completed Phase 3 Interventional

Simvastatin in Aneurysmal Subarachnoid Haemorrhage (STASH) a Multicentre Randomised Controlled Clinical Trial

NCT00731627
View directory record Official record
Conditions
Subarachnoid Haemorrhage
Interventions
placebo, simvastatin
Drug
Lead sponsor
Cambridge University Hospitals NHS Foundation Trust
Other
Eligibility
18 Years to 65 Years
Enrollment
803 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2014
U.S. locations
2
States / cities
Gainesville, Florida • Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 25, 2014 · Synced Oct 2, 2026, 5:21 AM EDT
Completed Not applicable Interventional Results available

Pivotal Study of the LVIS (Low Profile Visualized Intraluminal Support)

NCT01793792
View directory record Official record
Conditions
Intracranial Aneurysms
Interventions
LVIS™ and LVIS™ Jr
Device
Lead sponsor
Microvention-Terumo, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
21
States / cities
Phoenix, Arizona • Carmichael, California • Englewood, Colorado + 17 more
Source: ClinicalTrials.gov public record
Updated Jun 22, 2025 · Synced Oct 2, 2026, 5:21 AM EDT
Recruiting No phase listed Observational

Stroke Thrombectomy and Aneurysm Registry

NCT04994756
View directory record Official record
Conditions
Stroke, Thromboses, Intracranial, Aneurysm, Brain
Interventions
Stroke/Thrombectomy/Aneurysm-specific surgical procedures
Procedure
Lead sponsor
Medical University of South Carolina
Other
Eligibility
1 Year to 120 Years
Enrollment
40,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2055
U.S. locations
54
States / cities
Birmingham, Alabama • Loma Linda, California • Santa Barbara, California + 48 more
Source: ClinicalTrials.gov public record
Updated Dec 24, 2025 · Synced Oct 2, 2026, 5:21 AM EDT
Not yet recruiting No phase listed Observational

Perioperative Risk in Patients on Chronic Aspirin Undergoing Craniotomy

NCT07086183
View directory record Official record
Conditions
Aneurysm Cerebral
Interventions
Observation
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Oct 2, 2026, 5:21 AM EDT
Suspended Not applicable Interventional

The Effect of Sympathetic Modulation on Cerebral Vasospasm Secondary to Aneurysmal Subarachnoid Hemorrhage

NCT06443177
View directory record Official record
Conditions
Vasospasm, Cerebral, Aneurysmal Subarachnoid Hemorrhage
Interventions
Vectris trial leads and stimulation, Sham
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 65 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2028 – 2031
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Oct 2, 2026, 5:21 AM EDT