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ClinicalTrials.gov public records Last synced May 22, 2026, 3:46 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–46 of 22 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Ankle Instability Clear all
Not yet recruiting No phase listed Observational Accepts healthy volunteers
View directory record Official record
Conditions
Chronic Ankle Instability, CAI, Ankle Sprain, Healthy
Interventions
Cobra Ankle Arthrometer
Device
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 40 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 8, 2025 · Synced May 22, 2026, 3:46 AM EDT
Not listed Not applicable Interventional
View directory record Official record
Conditions
Lateral Ankle Instability
Interventions
Modified Brostrum procedure with Internal Brace Augmentation, Modified Brostrum procedure
Device
Lead sponsor
Arthrex, Inc.
Industry
Eligibility
18 Years and older
Enrollment
154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
3
States / cities
Chicago, Illinois • Las Vegas, Nevada • Logan, Utah
Source: ClinicalTrials.gov public record
Updated Mar 15, 2021 · Synced May 22, 2026, 3:46 AM EDT
Completed No phase listed Observational Accepts healthy volunteers
View directory record Official record
Conditions
Joint Instability
Interventions
Not listed
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
5 Years and older
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced May 22, 2026, 3:46 AM EDT
Terminated Not applicable Interventional
View directory record Official record
Conditions
Ankle Fractures
Interventions
Fibular intramedullary nail, Open reduction and internal fixation
Procedure
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 85 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 15, 2024 · Synced May 22, 2026, 3:46 AM EDT
Not listed Phase 1 Interventional
View directory record Official record
Conditions
Chronic Ankle Instability
Interventions
Neuromuscular Electrical Stimulation, Transcutaneous Electrical Nerve Stimulation
Device
Lead sponsor
Appalachian State University
Other
Eligibility
18 Years to 35 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Boone, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 25, 2020 · Synced May 22, 2026, 3:46 AM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Chronic Ankle Instability
Interventions
Neurocognitive Ankle Training for Instablity to Optimize Neuromusculoskeletal outcomes (NATION), Evidence-Based
Other
Lead sponsor
Womack Army Medical Center
Federal
Eligibility
18 Years to 44 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Lexington, Kentucky • Fort Bragg, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced May 22, 2026, 3:46 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Ankle Inversion Sprain, Chronic Instability of Joint
Interventions
Joint Mobilization, Massage
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 35 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 26, 2021 · Synced May 22, 2026, 3:46 AM EDT
Completed Phase 2 Interventional
View directory record Official record
Conditions
Chronic Ankle Instability
Interventions
Ankle Joint Mobilization, Foot Massage, Calf Stretching
Other
Lead sponsor
Joel Thompson
Other
Eligibility
18 Years to 45 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
2
States / cities
Ithaca, New York • Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 25, 2018 · Synced May 22, 2026, 3:46 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Ankle Injuries
Interventions
Balance training
Behavioral
Lead sponsor
Old Dominion University
Other
Eligibility
18 Years to 40 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated May 6, 2024 · Synced May 22, 2026, 3:46 AM EDT
Completed No phase listed Observational Results available
View directory record Official record
Conditions
Supination-external Rotation Ankle Fractures
Interventions
Not listed
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Oct 24, 2019 · Synced May 22, 2026, 3:46 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Ankle Injuries, Ankle Inversion Sprain
Interventions
External focus of attention visual feedback, External focus of attention auditory feedback, Internal focus of attention video feedback, No feedback
Other
Lead sponsor
University of North Carolina, Charlotte
Other
Eligibility
18 Years to 40 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 18, 2024 · Synced May 22, 2026, 3:46 AM EDT
Withdrawn Not applicable Interventional
View directory record Official record
Conditions
Ankle Injury
Interventions
Balance Training
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 45 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Apr 18, 2016 · Synced May 22, 2026, 3:46 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers
View directory record Official record
Conditions
Healthy
Interventions
Not listed
Lead sponsor
National Center for Research Resources (NCRR)
NIH
Eligibility
15 Years to 23 Years
Healthy volunteers
Accepts healthy volunteers
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Jun 23, 2005 · Synced May 22, 2026, 3:46 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Injuries, Ankle, Sprain of Foot
Interventions
Intrinsic Foot Strengthening, Joint Mobilization
Other
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 50 Years
Enrollment
115 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated May 2, 2017 · Synced May 22, 2026, 3:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Chronic Ankle Instability, Ankle Sprains, Ankle Rehabilitation
Interventions
Resistance Band Ankle Rehabilitation, Biomechanical Ankle Platform System Rehabilitation, Combination Rehabilitation
Other
Lead sponsor
Georgia State University
Other
Eligibility
15 Years to 18 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
7
States / cities
Atlanta, Georgia • College Park, Georgia • Decatur, Georgia + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 14, 2018 · Synced May 22, 2026, 3:46 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Other Instability, Ankle and Foot
Interventions
Strain Counterstrain, Sham strain counterstrain
Other
Lead sponsor
Long Island University
Other
Eligibility
18 Years to 55 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Dec 31, 2013 · Synced May 22, 2026, 3:46 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Ankle Sprains, Chronic Ankle Instability
Interventions
CBPT/HEP, HEP Only
Behavioral
Lead sponsor
Creighton University
Other
Eligibility
19 Years to 35 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Nov 19, 2025 · Synced May 22, 2026, 3:46 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Joint Instability
Interventions
Dr. Scholl's Prototype Ankle Brace, Dr. Scholl's Prototype Knee Brace
Device
Lead sponsor
Bayer
Industry
Eligibility
18 Years to 65 Years
Enrollment
183 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
2
States / cities
Colorado Springs, Colorado • Richardson, Texas
Source: ClinicalTrials.gov public record
Updated Dec 11, 2018 · Synced May 22, 2026, 3:46 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Ankle Sprains
Interventions
High Velocity Low Amplitude mobilization, Exercise protocol
Other
Lead sponsor
Shenandoah University
Other
Eligibility
18 Years to 35 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
2
States / cities
Fayetteville, North Carolina • Winchester, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 16, 2018 · Synced May 22, 2026, 3:46 AM EDT
Active, not recruiting Not applicable Interventional
View directory record Official record
Conditions
Ankle Injuries, Ankle Sprains
Interventions
Standard of Care Rehabilitation (SOC), Foot Intensive Rehabilitation (FIRE)
Behavioral
Lead sponsor
Matthew Hoch
Other
Eligibility
18 Years to 44 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced May 22, 2026, 3:46 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Chronic Ankle Instability
Interventions
Real-world vibration feedback gait retraining
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 35 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 7, 2023 · Synced May 22, 2026, 3:46 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Ankle (Ligaments); Instability (Old Injury)
Interventions
Balance Training, STARS
Behavioral
Lead sponsor
University of North Carolina, Charlotte
Other
Eligibility
18 Years to 35 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 10, 2017 · Synced May 22, 2026, 3:46 AM EDT