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ClinicalTrials.gov public records Last synced Nov 15, 2026, 2:08 AM EST

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Showing 49–72 of 85 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Ankle Pathology Clear all

Conditions: Peripheral Nervous System Diseases, Gait Disorders, Neurologic, Foot Drop, Mobility Limitation
Interventions: Seated Ankle Robot Training; Device
Lead sponsor: Baltimore VA Medical Center; Federal
Eligibility: 18 Years to 88 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2028
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Multiple Sclerosis
Interventions: Ankle-bot, Conventional focused ankle therapy; Device · Other
Lead sponsor: Mount Sinai Rehabilitation Hospital; Other
Eligibility: 25 Years to 65 Years
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Hartford, Connecticut

Conditions: Hindfoot Arthrodesis, Hindfoot Pathologies
Interventions: Not listed
Lead sponsor: AO Clinical Investigation and Publishing Documentation; Other
Eligibility: Not listed
Enrollment: 39 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 3
States / cities: Rancho Mirage, California • Charleston, South Carolina • Seattle, Washington

Conditions: Stroke, Hemiplegia
Interventions: Odstock Dropped-Foot Stimulator (ODFS), Conventional Standard of Care, Traditional Physical Therapy Treatment; Device · Other · Procedure
Lead sponsor: MetroHealth Medical Center; Other
Eligibility: 18 Years to 80 Years
Enrollment: 110 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2010
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Pain, Postoperative, Pain, Acute Postoperative, Ankle Fractures, Ankle Injuries and Disorders
Interventions: Exparel, Peripheral Nerve Block; Drug
Lead sponsor: St. Luke's Hospital, Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 248 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Bethlehem, Pennsylvania

Conditions: Narcotic Consumption, Pain, Wound Healing, Patient Satisfaction
Interventions: Iceman® Cold Therapy unit (djOrtho), Ice; Device · Other
Lead sponsor: OrthoCarolina Research Institute, Inc.; Other
Eligibility: Not listed
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Charlotte, North Carolina

Conditions: Arthritis, Femoroacetabular Impingement, Osteochondritis Dissecans, Hip Fractures, Ankle Fractures, Tibial Fractures
Interventions: Decision tool, Standard treatment information; Other
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 85 Years
Enrollment: 2,310 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2027
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Ankle Arthrodesis or Arthroplasty, Hindfoot Fusion, Ankle Deformity, Ankle Disease, Hindfoot Arthrodesis, Hindfoot Pathologies
Interventions: MagnetOs, Autograft; Device · Other
Lead sponsor: Kuros Biosurgery AG; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 126 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 7
States / cities: Sacramento, California • Vail, Colorado • Columbus, Georgia + 4 more

Conditions: Foot Injuries and Disorders
Interventions: Structure Sensor; Device
Lead sponsor: University of Iowa; Other
Eligibility: 18 Years to 75 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Ankle Sprains, Ankle Injuries and Disorders
Interventions: Walking, Rucking, Running; Other
Lead sponsor: Danielle Torp; Other
Eligibility: 18 Years to 45 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2028
U.S. locations: 2
States / cities: Lexington, Kentucky • Charlotte, North Carolina

Conditions: Primary Body Region (Arranged Most Common to Least), Lumbar/SI, Knee, Shoulder, Cervical/Thoracic, Foot/Ankle, Hip, Elbow, Neurological, Vestibular, Pelvic Floor, TMJ, Fibromyalgia, Headaches, Lymphedema
Interventions: Not listed
Lead sponsor: ATI Holdings, LLC; Industry
Eligibility: Not listed
Enrollment: 4,000,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Downers Grove, Illinois

Conditions: Acute Pain, Ankle Sprain
Interventions: Diclofenac Sodium, Matching Placebo Patch; Drug
Lead sponsor: Cerimon Pharmaceuticals; Industry
Eligibility: 17 Years to 75 Years
Enrollment: 219 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Achilles Tendinopathy, Ankle Strain, Achilles Tendon Pain, Achilles Tendonitis
Interventions: Ankle mobilization, Sham treatment; Procedure
Lead sponsor: Philadelphia College of Osteopathic Medicine; Other
Eligibility: 18 Years and older
Enrollment: 38 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Suwanee, Georgia

Conditions: Pain
Interventions: Clonidine, ropivacaine; Drug
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 19 Years and older
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Injury
Interventions: Narrative, Control; Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older
Healthy volunteers: Accepts healthy volunteers
Timeline: Started 2013
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Pareses, Lower Extremity
Interventions: C-Brace; Device
Lead sponsor: Otto Bock Healthcare Products GmbH; Industry
Eligibility: Not listed
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2026
U.S. locations: 70
States / cities: Harrison, Arkansas • Rogers, Arkansas • San Diego, California + 63 more

Conditions: Diabetic Foot Ulcer, Diabetes Mellitus, Foot Ulcer, Foot Ulcer, Diabetic, Ulcer, Ulcer Foot, Ulcer, Leg, Ankle Ulcer
Interventions: Total Contact Soft Cast, Cam Boot; Device
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2027
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Ankle Injuries and Disorders
Interventions: Anodal tDCS, Sham tDCS; Device
Lead sponsor: University of Miami; Other
Eligibility: 18 Years to 45 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Coral Gables, Florida

Conditions: Chronic Pain, Ankle Fracture Surgery, Regional Anesthesia
Interventions: Ropivacaine, Nerve block; Drug · Procedure
Lead sponsor: University of Cincinnati; Other
Eligibility: 18 Years to 65 Years
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 2
States / cities: Cincinnati, Ohio • West Chester, Ohio

Conditions: Cerebrovascular Accident, Post-polio Syndrome, Spinal Cord Injuries, Multiple Sclerosis, Muscular Dystrophy, Paralysis
Interventions: Indego Nomad® Powered Knee-Ankle-Foot Orthosis (P-KAFO) (Parker Hannifin Corp., Cleveland, OH); Device
Lead sponsor: Shirley Ryan AbilityLab; Other
Eligibility: 18 Years to 89 Years
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Pressure Ulcer, Ankle, Prosthesis User, Prosthesis Durability, Mobility Limitation, Skin Wound, Amputation; Traumatic, Foot, Amputation, Limb Deficiencies
Interventions: PROPRIO FOOT® by Ossur & Empower ankle by Ottobock; Device
Lead sponsor: Indiana University; Other
Eligibility: 18 Years and older
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Chronic Tendinopathy
Interventions: PNT + PRP, PNT alone; Procedure
Lead sponsor: Hospital for Special Surgery, New York; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2019
U.S. locations: 2
States / cities: New York, New York

Conditions: Ankle Sprains, Telerehabilitation, Analgesic, Opioid, Analgesics, Non-narcotic, Anti-Inflammatory Agents, Non-Steroidal, Implementation Science, Acute Pain, Quality of Life
Interventions: Telehealth Protocol, Usual Care; Other
Lead sponsor: Kyle Kosik; Other
Eligibility: 15 Years to 35 Years
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Achilles Tendon Repairs/Reconstructions, Pilon Fracture of Tibia, Tibial Plateau Fracture, Ankle Fracture (Bimalleolar Equivalent, Bimalleolar, or Trimalleolar), Calcaneus Fractures, Talus Fracture, Wound Infection Deep, Wound Infection Post-Traumatic, Wound Dehiscence, Surgical
Interventions: Nitroglycerin Ointment 2%; Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 2
States / cities: Baltimore, Maryland

Search by objective public record fields.

Seated Ankle Robot for Foot Drop in Aging and Disabled Populations: A Demonstration Project

Effects of Targeted Lower Extremity Joint Training on Multiple Sclerosis (MS) Gait Abnormalities

Clinical Experience With the Hindfoot Arthrodesis Nail for the Surgical Treatment of Ankle and Hindfoot Pathologies

Functional Electrical Stimulation for Footdrop in Hemiparesis

Exparel Use in Peripheral Nerve Blocks and Local Infiltration for Foot and Ankle Surgery

Motorized Continuous Cold Therapy Versus Standard Post-op Icing Protocol for Two Foot and Ankle Procedures

Conjoint Analysis of Patient Preferences in Joint Interventions

A Prospective, Randomized, Single-blind, Controlled, Multi-center Study to Assess the Safety and Performance of MagnetOsTM Compared to Autogenous Bone Graft in Patients Undergoing Hindfoot or Ankle Fusions.

SCANLOAD: The Effect of Limb Loading on Lower Limb Geometry

Auditory Biofeedback Gait Training Individuals With Chronic Ankle Instability

ATI Evidence-based Guide Investigating Clinical Services

Diclofenac Patch for Treatment of Acute Pain Due to Mild to Moderate Ankle Sprain

A Study Examining Changes in Pain After Manual Therapy in People With Achilles Tendon Pain

Effectiveness of Perineural Clonidine as an Adjuvant With Ropivacaine for Popliteal Nerve Block in Patients Undergoing Foot and Ankle Surgery

Stories to Educate Patients With Ankle, Foot, and Knee Injuries

C-Brace Prospective Registry

Total Contact Soft Cast in Diabetic Foot Ulcers

Balance Training With tDCS for CAI

Anesthesia for Pain After Ankle Fracture Surgery

Nomad P-KAFO Study

Limb Health and Socket Pressure in Response to Powered Ankle Protheses

Percutaneous Needle Tenotomy (PNT) Versus Platelet Rich Plasma (PRP) With PNT in the Treatment of Chronic Tendinosis

Telehealth Delivered Physical Rehabilitation for an Ankle Sprain

Enhancing Wound Perfusion in High-Risk Lower Extremity Orthopaedic Surgery: A Study on Nitropaste Using Intraoperative SPY Imaging.