- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Pain, Postoperative
- Interventions
- Tranexamic Acid, Placebo
- Drug
- Lead sponsor
- Dave Bernholt
- Other
- Eligibility
- 14 Years to 25 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 6
- States / cities
- Skokie, Illinois • St Louis, Missouri • Durham, North Carolina + 3 more
Search Results
Search by objective public record fields.
Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results come from ClinicalTrials.gov. When the live registry is unavailable, a clearly labeled stored copy may be shown.
These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Showing 25–48
of 80
matching trials from the live ClinicalTrials.gov search.
- Conditions
- ACL Tear
- Interventions
- Delfi's PTS Personalized Tourniquet System for Blood Flow Restriction Group, Standard ACL rehab
- Device · Other
- Lead sponsor
- Candice Dunkin, MS, LAT, ATC
- Other
- Eligibility
- 16 Years to 22 Years
- Enrollment
- 19 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2025
- U.S. locations
- 1
- States / cities
- Fort Wayne, Indiana
- Conditions
- Rupture of Anterior Cruciate Ligament
- Interventions
- Not listed
- Lead sponsor
- Vanderbilt University Medical Center
- Other
- Eligibility
- 12 Years to 35 Years
- Enrollment
- 67 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2012
- U.S. locations
- 1
- States / cities
- Nashville, Tennessee
- Conditions
- Knee Injury, ACL Injury, Meniscus Tear, Hispanic or Latino, Adolescent
- Interventions
- Educational program and patient navigator
- Behavioral
- Lead sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
- Other
- Eligibility
- 14 Years to 18 Years
- Enrollment
- 80 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2027 – 2029
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- ACL - Anterior Cruciate Ligament Rupture
- Interventions
- Bio-ACL, amnion wrap and BMAC
- Procedure · Device
- Lead sponsor
- Andrews Research & Education Foundation
- Other
- Eligibility
- 18 Years to 35 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2022
- U.S. locations
- 1
- States / cities
- Gulf Breeze, Florida
- Conditions
- Anterior Cruciate Ligament Tear, Knee Injuries, Sport Injury
- Interventions
- Blood flood restriction cuff
- Device
- Lead sponsor
- Henry Ford Health System
- Other
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2022
- U.S. locations
- 1
- States / cities
- West Bloomfield, Michigan
- Conditions
- Anterior Cruciate Ligament Rupture
- Interventions
- Blood Flow Restriction Therapy, ACL Reconstruction rehabilitation
- Device · Other
- Lead sponsor
- Inova Health Care Services
- Other
- Eligibility
- 13 Years to 50 Years
- Enrollment
- 49 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2022
- U.S. locations
- 1
- States / cities
- Fairfax, Virginia
- Conditions
- Anterior Cruciate Ligament (ACL) Tear, Sports Injuries in Children, Analgesia, Pain, Postoperative
- Interventions
- Ropivacaine 0.2% Injectable Solution
- Drug
- Lead sponsor
- Texas Scottish Rite Hospital for Children
- Other
- Eligibility
- 13 Years to 21 Years
- Enrollment
- 160 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2028
- U.S. locations
- 1
- States / cities
- Frisco, Texas
- Conditions
- Anterior Cruciate Ligament (ACL) Tear, Anterior Cruciate Ligament Reconstruction Rehabilitation
- Interventions
- Joint Manipulation
- Other
- Lead sponsor
- University of North Carolina, Chapel Hill
- Other
- Eligibility
- 18 Years to 35 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Chapel Hill, North Carolina
- Conditions
- ACL Tear, ACL Injury, Arthroscopy, Anterior Cruciate Ligament Tear
- Interventions
- ACL reconstruction with bone marrow, demineralized bone marix, and internal brace augmentation, Standard ACL reconstruction with all inside technique
- Procedure
- Lead sponsor
- Marshall University
- Other
- Eligibility
- 14 Years to 60 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2023
- U.S. locations
- 1
- States / cities
- Huntington, West Virginia
- Conditions
- Anterior Cruciate Ligament Rupture
- Interventions
- BioCleanse Tibialis tendon
- Other
- Lead sponsor
- RTI Surgical
- Industry
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017
- U.S. locations
- 1
- States / cities
- Phoenix, Arizona
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear, Arthrofibrosis of Knee
- Interventions
- Werewolf FLOW 50, Control
- Device · Other
- Lead sponsor
- University of Colorado, Denver
- Other
- Eligibility
- 12 Years to 18 Years
- Enrollment
- 182 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2024
- U.S. locations
- 3
- States / cities
- Aurora, Colorado • Broomfield, Colorado • Highlands Ranch, Colorado
- Conditions
- Anterior Cruciate Ligament Tear
- Interventions
- Regenexx SD, Exercise Therapy
- Procedure · Other
- Lead sponsor
- Regenexx, LLC
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2022
- U.S. locations
- 1
- States / cities
- Broomfield, Colorado
- Conditions
- ACL Tear, Post Operative Pain
- Interventions
- Iovera, Celecoxib, Acetaminophen, Oxycodone, Tramadol, Bupivacaine Hydrochloride, Acetaminophen 500Mg Cap
- Device · Drug
- Lead sponsor
- Matthew Varacallo
- Other
- Eligibility
- 15 Years and older
- Enrollment
- 32 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- DuBois, Pennsylvania
- Conditions
- ACL - Anterior Cruciate Ligament Deficiency, ACL Injury, ACL Tear
- Interventions
- Patients undergoing ACL reconstruction with or without a tourniquet
- Procedure
- Lead sponsor
- OrthoCarolina Research Institute, Inc.
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Charlotte, North Carolina
- Conditions
- Anterior Cruciate Ligament Rupture
- Interventions
- Blood Flow Restriction using Delfi Personalized Tourniquet System
- Device
- Lead sponsor
- Children's Healthcare of Atlanta
- Other
- Eligibility
- 12 Years to 18 Years
- Enrollment
- 120 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2023
- U.S. locations
- 1
- States / cities
- Atlanta, Georgia
- Conditions
- ACL Injury, ACL - Anterior Cruciate Ligament Rupture, ACL Sprain, ACL Tear
- Interventions
- CBPT-ACLR, Education
- Behavioral · Other
- Lead sponsor
- Vanderbilt University Medical Center
- Other
- Eligibility
- 14 Years to 35 Years
- Enrollment
- 90 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2020
- U.S. locations
- 2
- States / cities
- Garfield Heights, Ohio • Nashville, Tennessee
- Conditions
- Anterior Cruciate Ligament (ACL) Tear, Physical Therapy
- Interventions
- Arm A - blood flow restriction training, Arm B - standard of care
- Other
- Lead sponsor
- Brian W. Noehren
- Other
- Eligibility
- 15 Years to 40 Years
- Enrollment
- 55 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2023
- U.S. locations
- 2
- States / cities
- Lexington, Kentucky
- Conditions
- Posttraumatic Osteoarthritis, Anterior Cruciate Ligament (ACL) Rupture
- Interventions
- Synovial Fluid withdrawal at the preoperative clinic visit, Platelet-Rich Plasma (PRP) preparation and injection, Synovial fluid withdrawal at the time of surgery, 3mL synovial fluid withdrawn at the preoperative visit
- Procedure
- Lead sponsor
- Rush University Medical Center
- Other
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 99 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture
- Interventions
- Bridge-Enhanced ACL Restoration (BEAR)
- Device
- Lead sponsor
- Miach Orthopaedics
- Industry
- Eligibility
- 12 Years to 80 Years
- Enrollment
- 250 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2034
- U.S. locations
- 11
- States / cities
- San Diego, California • Tampa, Florida • Atlanta, Georgia + 8 more
- Conditions
- Anterior Cruciate Ligament Rupture
- Interventions
- Single-injection femoral nerve block, Femoral nerve block 60-hour continuous injection, Saline (control) injection into femoral nerve envelope
- Procedure
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 14 Years to 65 Years
- Enrollment
- 270 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2001 – 2005
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear, Osteo Arthritis Knee
- Interventions
- Internal focus of attention feedback, External focus of attention feedback
- Other
- Lead sponsor
- University of North Carolina, Charlotte
- Other
- Eligibility
- 18 Years to 35 Years
- Enrollment
- 45 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2024
- U.S. locations
- 1
- States / cities
- Charlotte, North Carolina
- Conditions
- Osteoarthritis, Knee, Post-traumatic Osteoarthritis, ACL Tear
- Interventions
- Metformin, Placebo
- Drug
- Lead sponsor
- Brigham and Women's Hospital
- Other
- Eligibility
- 18 Years to 45 Years
- Enrollment
- 512 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2030
- U.S. locations
- 9
- States / cities
- Atlanta, Georgia • Iowa City, Iowa • Lexington, Kentucky + 6 more
- Conditions
- Anterior Cruciate Ligament Tear
- Interventions
- Ropivacaine injection
- Drug
- Lead sponsor
- Sujana Dontukurthy
- Other
- Eligibility
- Up to 21 Years
- Enrollment
- 7 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019
- U.S. locations
- 1
- States / cities
- Columbus, Ohio