- Conditions
- Anterior Cruciate Ligament Rupture
- Interventions
- Initial graft tension during ACL reconstruction surgery
- Procedure
- Lead sponsor
- Rhode Island Hospital
- Other
- Eligibility
- 15 Years to 50 Years
- Enrollment
- 168 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2004 – 2024
- U.S. locations
- 2
- States / cities
- Providence, Rhode Island
Search Results
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Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 25–48
of 24
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Anterior Cruciate Ligament Injuries
- Interventions
- The BEAR® Implant
- Device
- Lead sponsor
- Miach Orthopaedics
- Industry
- Eligibility
- 14 Years and older
- Enrollment
- 300 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2027
- U.S. locations
- 8
- States / cities
- Redwood City, California • Steamboat Springs, Colorado • Orlando, Florida + 5 more
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear, Arthrofibrosis of Knee
- Interventions
- Werewolf FLOW 50, Control
- Device · Other
- Lead sponsor
- University of Colorado, Denver
- Other
- Eligibility
- 12 Years to 18 Years
- Enrollment
- 182 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2024
- U.S. locations
- 3
- States / cities
- Aurora, Colorado • Broomfield, Colorado • Highlands Ranch, Colorado
- Conditions
- Knee Injury, ACL Injury, Meniscus Tear, Hispanic or Latino, Adolescent
- Interventions
- Not applicable- observational study
- Other
- Lead sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
- Other
- Eligibility
- 14 Years to 18 Years
- Enrollment
- 80 participants
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Anterior Cruciate Ligament Tear, Knee Injuries, Sport Injury
- Interventions
- Blood flood restriction cuff
- Device
- Lead sponsor
- Henry Ford Health System
- Other
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2022
- U.S. locations
- 1
- States / cities
- West Bloomfield, Michigan
- Conditions
- ACL Injury, ACL - Anterior Cruciate Ligament Rupture, ACL, ACL - Anterior Cruciate Ligament Deficiency
- Interventions
- Ossur Rebound ACL Brace
- Device
- Lead sponsor
- Steadman Philippon Research Institute
- Other
- Eligibility
- 18 Years to 60 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Vail, Colorado
- Conditions
- Anterior Cruciate Ligament (ACL) Tear, Physical Therapy
- Interventions
- Arm A - blood flow restriction training, Arm B - standard of care
- Other
- Lead sponsor
- Brian W. Noehren
- Other
- Eligibility
- 15 Years to 40 Years
- Enrollment
- 55 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2023
- U.S. locations
- 2
- States / cities
- Lexington, Kentucky
- Conditions
- Anterior Cruciate Ligament Tear, Meniscal Tear, Cartilage Injury, Bone Bruising
- Interventions
- Not listed
- Lead sponsor
- State University of New York at Buffalo
- Other
- Eligibility
- Not listed
- Enrollment
- 1,646 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2025
- U.S. locations
- 1
- States / cities
- Buffalo, New York
- Conditions
- Anterior Cruciate Ligament Tear
- Interventions
- ACL Reconstruction (Bone Patellar Tendon Bone Graft), Bridge Enhanced ACL Restoration (BEAR)
- Procedure · Device
- Lead sponsor
- The Cleveland Clinic
- Other
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2027
- U.S. locations
- 6
- States / cities
- Boulder, Colorado • Bloomington, Minnesota • Cleveland, Ohio + 3 more
- Conditions
- Anterior Cruciate Ligament Tear
- Interventions
- Blood flow restriction
- Device
- Lead sponsor
- University of Washington
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2020
- U.S. locations
- 1
- States / cities
- Seattle, Washington
- Conditions
- ACL - Anterior Cruciate Ligament Rupture
- Interventions
- Biocomposite intereference screw femoral tunnel fixation, Endobutton (Tightrope) femoral tunnel fixation
- Device
- Lead sponsor
- Kelsey-Seybold Clinic
- Other
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 37 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2017
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- ACL Injury, ACL - Anterior Cruciate Ligament Rupture, ACL Sprain, ACL Tear
- Interventions
- CBPT-ACLR, Education
- Behavioral · Other
- Lead sponsor
- Vanderbilt University Medical Center
- Other
- Eligibility
- 14 Years to 35 Years
- Enrollment
- 90 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2020
- U.S. locations
- 2
- States / cities
- Garfield Heights, Ohio • Nashville, Tennessee
- Conditions
- Blood Flow Restriction, ACL Tear, ACL Injury
- Interventions
- Blood Flow Restriction using Delfi Personalized Tourniquet System
- Device
- Lead sponsor
- Connecticut Children's Medical Center
- Other
- Eligibility
- 12 Years to 18 Years
- Enrollment
- 47 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2023
- U.S. locations
- 1
- States / cities
- Farmington, Connecticut
- Conditions
- ACL Injury, ACL Tear
- Interventions
- Patients will be randomized into one of two study arms: (1) concomitant ACL and ALL reconstruction or (2) ACL reconstruction alone.
- Procedure
- Lead sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
- Other
- Eligibility
- Up to 18 Years
- Enrollment
- 240 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2030
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Anterior Cruciate Ligament Tear, Pain, Postoperative, Opioid Use
- Interventions
- Liposomal bupivacaine, Bupivacaine Hydrochloride
- Drug
- Lead sponsor
- Carilion Clinic
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2022
- U.S. locations
- 1
- States / cities
- Roanoke, Virginia
- Conditions
- Anterior Cruciate Ligament (ACL) Tear
- Interventions
- Single-injection sciatic PNB, Continuous sciatic PNB
- Drug
- Lead sponsor
- Children's Hospital Medical Center, Cincinnati
- Other
- Eligibility
- 10 Years to 18 Years
- Enrollment
- 141 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2024
- U.S. locations
- 1
- States / cities
- Cincinnati, Ohio
- Conditions
- ACL Tears
- Interventions
- MRI
- Diagnostic Test
- Lead sponsor
- Skye Biologics Holdings, LLC
- Industry
- Eligibility
- 14 Years to 50 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Sugar Land, Texas
- Conditions
- ACL, ACL Injury, Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture, Anesthesia
- Interventions
- Acupuncture + Standard of Care
- Other
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 12 Years to 80 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- ACL Tear
- Interventions
- Safe Return to Play Following ACL Reconstruction Checklist
- Diagnostic Test
- Lead sponsor
- Rothman Institute Orthopaedics
- Other
- Eligibility
- 15 Years to 35 Years
- Enrollment
- 222 participants
- Timeline
- 2016 – 2020
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- ACL Tear
- Interventions
- ACL reconstruction with BTB autograft with internal brace augmentation (suture tape), ACL reconstruction with BTB autograft without internal brace augmentation (suture tape), Standardized Rehabilitation Protocol
- Procedure · Other
- Lead sponsor
- Columbia University
- Other
- Eligibility
- 12 Years and older
- Enrollment
- 200 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2032
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Posttraumatic Osteoarthritis, Anterior Cruciate Ligament (ACL) Rupture
- Interventions
- Synovial Fluid withdrawal at the preoperative clinic visit, Platelet-Rich Plasma (PRP) preparation and injection, Synovial fluid withdrawal at the time of surgery, 3mL synovial fluid withdrawn at the preoperative visit
- Procedure
- Lead sponsor
- Rush University Medical Center
- Other
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 99 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Rupture of Anterior Cruciate Ligament, Tear of Anterior Cruciate Ligament
- Interventions
- Mepivacaine, adductor canal continuous nerve catheter, Normal Saline as bolus followed by bupivacaine, adductor canal nerve block, ropivacaine and dexamethasone, Propofol, Fentanyl
- Drug · Procedure
- Lead sponsor
- Vanderbilt University Medical Center
- Other
- Eligibility
- 14 Years and older
- Enrollment
- 59 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2018
- U.S. locations
- 1
- States / cities
- Nashville, Tennessee
- Conditions
- Bone Diseases, Infectious, Musculoskeletal Diseases, Joint Diseases, Osteoarthritis, ACL Tear, Cartilage Degeneration
- Interventions
- MRI
- Diagnostic Test
- Lead sponsor
- Xiaojuan Li
- Other
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 88 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2026
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Anterior Cruciate Ligament Tear, Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
- Interventions
- Intraosseous Morphine
- Drug
- Lead sponsor
- The Methodist Hospital Research Institute
- Other
- Eligibility
- 18 Years to 40 Years
- Enrollment
- 84 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2029
- U.S. locations
- 1
- States / cities
- Houston, Texas