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ClinicalTrials.gov public records Last synced Nov 14, 2026, 11:57 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 680 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Antibiotic Therapy Clear all

Conditions: Surgical Site Infection
Interventions: topical irrigation with gentamicin (80mg diluted in 1L 0.9% normal saline), topical irrigation with sterile normal saline (NS), intravenous (IV) prophylactic antibiotic; Drug
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years and older
Enrollment: 39 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Obesity, Morbid, Hypertension, Bariatric Surgery Candidate
Interventions: Antibiotic; Drug
Lead sponsor: Medical College of Wisconsin; Other
Eligibility: 18 Years to 70 Years
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Milwaukee, Wisconsin

Conditions: Kidney Stone, Renal Stone, Infection, Bacterial
Interventions: NGS + Antibiotic Recommendation, Standard of Care treatment; Other · Procedure
Lead sponsor: The University of Texas Health Science Center at San Antonio; Other
Eligibility: 18 Years and older
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 3
States / cities: San Antonio, Texas

Conditions: Urinary Tract Infections
Interventions: Gentamicin, Standard of Care; Drug
Lead sponsor: Mercy Health Ohio; Other
Eligibility: 18 Years and older · Female only
Enrollment: 160 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Youngstown, Ohio

Conditions: First Trimester Abortion
Interventions: Azithromycin, Doxycycline, Metronidazole, Placebo; Drug
Lead sponsor: Medstar Health Research Institute; Other
Eligibility: 18 Years and older · Female only
Enrollment: 181 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2017
U.S. locations: 2
States / cities: Washington D.C., District of Columbia • Silver Spring, Maryland

Conditions: Abdominal Abscess
Interventions: Gentamicin Sulfate Inj 20mg/2ml vial for injection, Clindamycin phosphate 6 mg/1ml for injection, Placebo; Drug · Other
Lead sponsor: University of Iowa; Other
Eligibility: 18 Years to 80 Years
Enrollment: 2 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Inflammation at Mini-screw Insertion Site, Mobility, Mini-screw
Interventions: Amoxicillin, Placebo oral capsule; Drug
Lead sponsor: St. Louis University; Other
Eligibility: 12 Years and older
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Pulp Necrosis
Interventions: Double Antibiotic Paste, Triple Antibiotic Paste, Mineral Trioxide Aggregate; Drug
Lead sponsor: The University of Texas Health Science Center at San Antonio; Other
Eligibility: 7 Years to 60 Years
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2015
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: UTI - Lower Urinary Tract Infection, Antibiotic Resistant Infection
Interventions: Ciprofloxacin; Drug
Lead sponsor: Iterum Therapeutics, International Limited; Industry
Eligibility: 18 Years and older · Female only
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Cary, North Carolina

Conditions: Late Effects of Surgery, Staphylococcus Aureus, Surgical Site Infection
Interventions: daptomycin; Drug
Lead sponsor: Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center; Other
Eligibility: 19 Years to 74 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Torrance, California

Conditions: Cystic Fibrosis, Chronic Bronchitis
Interventions: IV amikacin, PO azithromycin, IV ceftazidime, PO ciprofloxacin, IV meropenem, IV piperacillin-tazobactam, IV ticarcillin-clavulanate, IV tobramycin; Drug
Lead sponsor: Seattle Children's Hospital; Other
Eligibility: 14 Years and older
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2007
U.S. locations: 8
States / cities: Iowa City, Iowa • St Louis, Missouri • Cincinnati, Ohio + 4 more

Conditions: Foot Ulcer, Diabetic, Infection
Interventions: Gentamicin collagen sponge, Placebo; Drug · Other
Lead sponsor: Innocoll; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 612 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 86
States / cities: Anniston, Alabama • Mobile, Alabama • Mesa, Arizona + 67 more

Conditions: Pneumonia
Interventions: Use of procalcitonin as biomarker to guide therapy; Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 134 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013
U.S. locations: 1
States / cities: Eau Claire, Wisconsin

Conditions: Intestinal Microbiome, Febrile Neutropenia
Interventions: Piperacillin-tazobactam, cefepime; Drug
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 347 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2027
U.S. locations: 2
States / cities: Hackensack, New Jersey • New York, New York

Conditions: Total Knee Replacement
Interventions: hand mixed vancomycin, hand mixed tobramycin, pre-mixed tobramycin; Drug · Device
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Burns
Interventions: Vashe, Mafenide acetate; Device · Drug
Lead sponsor: Valleywise Health; Other
Eligibility: 18 Years and older
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Phoenix, Arizona

Conditions: Small Intestinal Bacterial Overgrowth Syndrome (SIBO), Small Bowel Bacterial Overgrowth Syndrome (SBBOS)
Interventions: Not listed
Lead sponsor: University of Florida; Other
Eligibility: Not listed
Enrollment: 944 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Gram Positive Bacterial Infection
Interventions: Daptomycin; Drug
Lead sponsor: Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA); Industry
Eligibility: 3 Months to 24 Months
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 8
States / cities: Little Rock, Arkansas • Orange, California • San Diego, California + 5 more

Conditions: Multiple Sclerosis
Interventions: Rifampin, Azithromycin; Drug
Lead sponsor: National Center for Research Resources (NCRR); NIH
Eligibility: 18 Years to 65 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Gram-negative Bacteremia
Interventions: Intravenous Antibiotics, Oral Antibiotics; Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 1,030 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 11
States / cities: San Francisco, California • Denver, Colorado • Baltimore, Maryland + 7 more

Conditions: Otitis Media, Antimicrobial Stewardship
Interventions: Education with personalized performance feedback, Use of digital otoscope; Other · Device
Lead sponsor: Boston Children's Hospital; Other
Eligibility: Not listed
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 1
States / cities: Wellesley, Massachusetts

Conditions: Open Fracture
Interventions: Not listed
Lead sponsor: Major Extremity Trauma Research Consortium; Other
Eligibility: 18 Years to 64 Years
Enrollment: 646 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2022
U.S. locations: 40
States / cities: San Diego, California • San Francisco, California • Denver, Colorado + 34 more

Conditions: Breast Cancer
Interventions: Tissue Expander (TE), Vancomycin and Gentamicin, Stimulan Rapid Cure; Procedure · Drug · Device
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 392 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 7
States / cities: Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more

Conditions: Bacteremia, Staphylococcus Aureus, Staphylococcus Aureus Bacteremia, Bacteremia Staph, Bacteremia Due to Staphylococcus Aureus
Interventions: AP-SA02, Placebo; Biological · Other
Lead sponsor: Armata Pharmaceuticals, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 56 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 23
States / cities: Tucson, Arizona • La Jolla, California • Los Angeles, California + 19 more

Search by objective public record fields.

Topical Antibiotic Irrigation (Gentamicin) in Prophylaxis of Midfacial Fracture Surgical Wounds

Antibiotics, Gastric Bypass, and the Microbiome

Antibiotic Selection Using Next Generation Sequencing vs Urine Culture

Single Dose Aminoglycosides for Acute Uncomplicated Cystitis in the Emergency Department Setting

A Randomized Controlled Trial of Three Antibiotic Regimens for First Trimester Abortions

Antibiotic Irrigations for Intra-Abdominal Drains

Antibiotics Prior to Mini-screw Implant Insertion

Treatment Outcome With a Revascularization Protocol Using the Triple Versus Double Antibiotic Paste

Efficacy of Ciprofloxacin for the Treatment of Uncomplicated Urinary Tract Infection (uUTI)

Pharmacokinetics of Daptomycin During Cardiopulmonary Bypass Surgery

Standard vs. Biofilm Susceptibility Testing in Cystic Fibrosis (CF)

Study of a Topical Gentamicin-Collagen Sponge Along With Systemic Antibiotic in Infected Diabetic Foot Ulcers

Procalcitonin Use in Pneumonia Patients in the Critical Care Setting

Choosing the Best Antibiotic to Protect Friendly Gut Bacteria During the Course of Stem Cell Transplant

Antibiotic Elution in Total Knee Arthroplasty

Vashe Wound Therapy Study

Retrospective Analysis of Treatment Outcomes in Patients With Bacterial Overgrowth Syndrome Diagnosed by D-Xylose Breath Testing

Pharmacokinetics (PK) and Safety Evaluation of Daptomycin in Children Ages 3-24 Months With Proven or Suspected Gram-positive Infections or Peri-Operative Subjects Receiving Prophylactic Antibiotics

Antibiotic Treatment Trial Directed Against Chlamydia Pneumonia in Multiple Sclerosis

Gram-Negative Bloodstream Infection Oral Antibiotic Therapy Trial

Digital Otoscope Versus Education and Feedback for Otitis Media in Young Children

Assessment of Severe Extremity Wound Bioburden at the Time of Definitive Wound Closure or Coverage

A Study of Antibiotic Delivery to Prevent Infection After Breast Tissue Expander Placement

Study Evaluating Safety, Tolerability, and Efficacy of Intravenous AP-SA02 in Subjects With S. Aureus Bacteremia