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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Antimicrobial Clear all
Not listed Early Phase 1 Interventional

Neomycin and Metronidazole Hydrochloride With or Without Polyethylene Glycol in Reducing Infection in Patients Undergoing Elective Colorectal Surgery

NCT03042091
View directory record Official record
Conditions
Colorectal Neoplasms, Diverticulitis, Inflammatory Bowel Diseases, Surgical Site Infection
Interventions
Polyethylene Glycol, Neomycin, Metronidazole Hydrochloride, Therapeutic Conventional Surgery
Drug · Procedure
Lead sponsor
Thomas Jefferson University
Other
Eligibility
19 Years and older
Enrollment
224 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 21, 2018 · Synced Jul 24, 2026, 3:04 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

VivaGel™ in Healthy Young Women

NCT00331032
View directory record Official record
Conditions
Herpes Simplex II
Interventions
3% w/w SPL7013 Gel, Placebo
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
18 Years to 24 Years · Female only
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 22, 2013 · Synced Jul 24, 2026, 3:04 AM EDT
Completed Phase 4 Interventional Results available

Project PROTECT: Protecting Nursing Homes From Infections and Hospitalization

NCT03118232
View directory record Official record
Conditions
Hospitalization, Infection
Interventions
Chlorhexidine gluconate (CHG), Iodophor (10% povidone-iodine)
Drug
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
13,952 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
28
States / cities
Anaheim, California • Bellflower, California • Capistrano Beach, California + 9 more
Source: ClinicalTrials.gov public record
Updated Dec 26, 2023 · Synced Jul 24, 2026, 3:04 AM EDT
Completed Not applicable Interventional

De-Implementation of Inappropriate Antimicrobial Use After Cardiac Device Procedures

NCT05020418
View directory record Official record
Conditions
Antibiotics Causing Adverse Effects in Therapeutic Use
Interventions
Chart Review
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
5,469 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Jul 24, 2026, 3:04 AM EDT
Completed Phase 3 Interventional

SIS Multicenter Study of Duration of Antibiotics for Intraabdominal Infection

NCT00657566
View directory record Official record
Conditions
Peritonitis
Interventions
duration of antibiotics
Other
Lead sponsor
University of Virginia
Other
Eligibility
16 Years and older
Enrollment
518 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
22
States / cities
Phoenix, Arizona • Sacramento, California • San Diego, California + 17 more
Source: ClinicalTrials.gov public record
Updated May 21, 2018 · Synced Jul 24, 2026, 3:04 AM EDT
Completed Phase 4 Interventional

NICU Antibiotics and Outcomes Trial

NCT03997266
View directory record Official record
Conditions
Microbial Colonization, Extreme Prematurity, Early-Onset Neonatal Sepsis, Late-Onset Neonatal Sepsis, Necrotizing Enterocolitis of Newborn, Death; Neonatal
Interventions
Ampicillin, Gentamycin, Normal saline
Drug
Lead sponsor
Michael Morowitz
Other
Eligibility
Up to 4 Hours
Enrollment
359 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
14
States / cities
Mobile, Alabama • San Diego, California • New Haven, Connecticut + 10 more
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Jul 24, 2026, 3:04 AM EDT
Completed Not applicable Interventional Results available

Ventilator-associated Pneumonia (VAP) Diagnostic Stewardship Trial

NCT05176353
View directory record Official record
Conditions
VAP - Ventilator Associated Pneumonia
Interventions
VAP diagnostic stewardship bundle
Other
Lead sponsor
University of Michigan
Other
Eligibility
Not listed
Enrollment
4,892 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 2, 2024 · Synced Jul 24, 2026, 3:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Rapid PCR to Guide Antibiotic Therapy at the Time of Prostate Biopsy

NCT03040050
View directory record Official record
Conditions
Antibiotic Therapy, Prostate Biopsy
Interventions
rPCR results, Control group
Other
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
50 Years and older · Male only
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Feb 4, 2020 · Synced Jul 24, 2026, 3:04 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Improving Antibiotic Use in Urgent Care Facilities

NCT03932708
View directory record Official record
Conditions
Antibiotic Side Effect, Behavioral Changes
Interventions
CDC Core Elements of Outpatient Stewardship
Behavioral
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
Not listed
Enrollment
700,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Murray, Utah
Source: ClinicalTrials.gov public record
Updated Mar 28, 2022 · Synced Jul 24, 2026, 3:04 AM EDT
Completed Phase 2 Interventional Results available

Safety and Efficacy of Mupirocin in Eradicating Colonization With S. Aureus in Critically Ill Infants

NCT01827358
View directory record Official record
Conditions
Staphylococcal Infection
Interventions
Mupirocin calcium
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
Up to 24 Months
Enrollment
155 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
6
States / cities
Atlanta, Georgia • Baltimore, Maryland • Kansas City, Missouri + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 6, 2017 · Synced Jul 24, 2026, 3:04 AM EDT
Completed Not applicable Interventional Results available

Antibiotic Selection Using Next Generation Sequencing vs Urine Culture

NCT04404855
View directory record Official record
Conditions
Kidney Stone, Renal Stone, Infection, Bacterial
Interventions
NGS + Antibiotic Recommendation, Standard of Care treatment
Other · Procedure
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
3
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Mar 11, 2024 · Synced Jul 24, 2026, 3:04 AM EDT
Completed Phase 3 Interventional Results available

Ceftazidime-Avibactam Compared With Doripenem Followed by Oral Therapy for Hospitalized Adults With Complicated UTIs (Urinary Tract Infections)

NCT01599806
View directory record Official record
Conditions
Complicated Urinary Tract Infection (cUTI) Including Acute Pyelonephritis
Interventions
Ceftazidime - Avibactam ( CAZ-AVI), Doripenem, Either switch to oral therapy: 500 mg of Ciprofloxacin (oral), or switch to oral therapy: 800 mg/160 mg of sulfamethoxazole/trimethoprim (oral)
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 90 Years
Enrollment
641 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
3
States / cities
Detroit, Michigan • St Louis, Missouri • Indiana, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 5, 2017 · Synced Jul 24, 2026, 3:04 AM EDT
Withdrawn Phase 2 Interventional

Bacteriophage Therapy in Patients With Prosthetic Joint Infections (PJI)

NCT05269134
View directory record Official record
Conditions
Prosthetic Joint Infection
Interventions
Bacteriophage, Placebo
Drug
Lead sponsor
Adaptive Phage Therapeutics, Inc.
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
10
States / cities
San Diego, California • Hartford, Connecticut • Idaho Falls, Idaho + 5 more
Source: ClinicalTrials.gov public record
Updated Nov 29, 2023 · Synced Jul 24, 2026, 3:04 AM EDT
Terminated Phase 4 Interventional Results available

Bezlotoxumab as Secondary Prophylaxis for C. Difficile in High-risk Hospitalized Patients Exposed to Antibiotics.

NCT03937999
View directory record Official record
Conditions
Clostridium Difficile
Interventions
Bezlotoxumab
Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
60 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Nov 8, 2022 · Synced Jul 24, 2026, 3:04 AM EDT
Completed Phase 2 Interventional

Efficacy Study of a Bioelectric Dressing Used With Negative Pressure Wound Therapy to Treat Diabetic and Pressure Ulcers

NCT01022216
View directory record Official record
Conditions
Wound Healing
Interventions
Procellera™ Wound Dressing with V.A.C.® Therapy, V.A.C.® Therapy
Device
Lead sponsor
Vomaris Innovations
Industry
Eligibility
18 Years to 90 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Feb 21, 2012 · Synced Jul 24, 2026, 3:04 AM EDT
Completed Phase 2 Interventional Results available

Rapid Hormonal Cycling as Treatment for Patients With Prostate Cancer: The Men's Cycle

NCT00586898
View directory record Official record
Conditions
Prostate, Cancer, Hormonal Cycling
Interventions
GnRH, Ketoconazole, Bicalutamide, Testosterone transdermal gel, Estrogen transdermal patch
Drug
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older · Male only
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2009
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 24, 2016 · Synced Jul 24, 2026, 3:04 AM EDT
Terminated Phase 1Phase 2 Interventional Results available

Inhaled Sodium Nitrite as an Antimicrobial for Cystic Fibrosis

NCT02694393
View directory record Official record
Conditions
Cystic Fibrosis
Interventions
sodium nitrite
Drug
Lead sponsor
Schmidhofer, Mark, MD
Individual
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 23, 2024 · Synced Jul 24, 2026, 3:04 AM EDT
Completed Phase 1 Interventional Results available

Investigation of the Efficacy of Antibiotics on Pulmonary Sarcoidosis

NCT01169038
View directory record Official record
Conditions
Pulmonary Sarcoidosis, Lung Function
Interventions
levaquin; ethambutol; rifampin and azithromycin.
Drug
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years to 75 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 30, 2012 · Synced Jul 24, 2026, 3:04 AM EDT
Withdrawn No phase listed Observational

Surveillance Study - Incidence of Antibiotic Resistance in Serial Gram-negative Bloodstream Isolates

NCT00394784
View directory record Official record
Conditions
Gram-negative Bacterial Infections
Interventions
Not listed
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 10, 2023 · Synced Jul 24, 2026, 3:04 AM EDT
Completed No phase listed Observational

The RESPOND Registry

NCT03286452
View directory record Official record
Conditions
Partial Thickness Wound, Pressure Ulcer, Venous Ulcer, Diabetic Ulcer, Surgical Wounds, Trauma Wounds, Draining Wounds, Chronic Vascular Ulcer
Interventions
PuraPly™ Antimicrobial Wound Matrix
Device
Lead sponsor
Organogenesis
Industry
Eligibility
18 Years and older
Enrollment
310 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
15
States / cities
Prescott Valley, Arizona • Jupiter, Florida • Miami, Florida + 12 more
Source: ClinicalTrials.gov public record
Updated Feb 26, 2019 · Synced Jul 24, 2026, 3:04 AM EDT
Completed No phase listed Observational

Blood Culture Improvement Guidelines and Diagnostic Stewardship for Antibiotic Reduction in Critically Ill Children

NCT03441126
View directory record Official record
Conditions
Sepsis, Bacteremia
Interventions
Multicenter Quality Improvement program
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
Not listed
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
5
States / cities
St Louis, Missouri • Cleveland, Ohio • Portland, Oregon + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 10, 2022 · Synced Jul 24, 2026, 3:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Analysis of the Effect of Antimicrobial Soap on Bacterial Survival

NCT02012348
View directory record Official record
Conditions
Survival of Bacteria on Skin After Using Different Soaps
Interventions
Antibacterial soap with triclocarban, Antibacterial soap + benzalkonium chloride, Control soap
Other
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 60 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Oct 2, 2019 · Synced Jul 24, 2026, 3:04 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

CAT BITE Antibiotic Prophylaxis for the Hand/Forearm (CATBITE)

NCT05846399
View directory record Official record
Conditions
Cat Bite, Hand Injuries, Arm Injury, Infection, Bacterial, Anti-bacterial Agents
Interventions
Amoxicillin/clavulanate, Ciprofloxacin, Clindamycin, Placebo (microcrystalline cellulose), Wound management
Drug · Other · Procedure
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Jul 24, 2026, 3:04 AM EDT
Completed No phase listed Observational

Study of Accuracy of New Diagnostic Technology to Guide Rapid Antibiotic Treatment for Serious Infections

NCT02796716
View directory record Official record
Conditions
INFECTIONS, Skin and Subcutaneous Tissue Bacterial Infections, Healthcare-associated Infection, Infection Due to Resistant Bacteria
Interventions
Testing on new technology called Accelerate ID/AST system
Device
Lead sponsor
Denver Health and Hospital Authority
Other
Eligibility
18 Years and older
Enrollment
2,102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 1, 2017 · Synced Jul 24, 2026, 3:04 AM EDT