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ClinicalTrials.gov public records Last synced Oct 21, 2026, 2:24 PM EDT

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Showing 25–48 of 302 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Anxiety, Generalized Clear all
Completed Not applicable Interventional

Adaptation and Feasibility of the Community-Based Anxiety Program Tailored for Autism (CAPTA)

NCT06046170
View directory record Official record
Conditions
Anxiety, Autism Spectrum Disorder, Separation Anxiety, Generalized Anxiety Disorder, Social Anxiety Disorder of Childhood
Interventions
Cognitive Behavioral Therapy, Treatment as Usual
Behavioral · Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
7 Years to 17 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
3
States / cities
Baltimore, Maryland • Philadelphia, Pennsylvania • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 21, 2026, 2:24 PM EDT
Completed Not applicable Interventional

CES for the Treatment of GAD in Young Adults

NCT06124014
View directory record Official record
Conditions
Generalized Anxiety Disorder
Interventions
At-Home Stimulation
Device
Lead sponsor
Electromedical Products International, Inc.
Industry
Eligibility
18 Years to 21 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Oct 21, 2026, 2:24 PM EDT
Recruiting Not applicable Interventional

Validating an Autonomous Interactive Internet-Based Delivery of an Empirically Supported Cognitive Behavioral Therapy for Comorbidity

NCT05117255
View directory record Official record
Conditions
Generalized Anxiety Disorder, Panic Disorder, Social Anxiety Disorder, Alcohol Use Disorder, Depression
Interventions
Negative Emotions and Addiction Tools Program (NEAT)- Cognitive Behavioral Therapy, Progressive Muscle Relaxation Training (PMRT)
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 65 Years
Enrollment
256 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Oct 21, 2026, 2:24 PM EDT
Completed Not applicable Interventional Results available

An Open Label Study of Clinical Utility and Patient Outcomes of the Genecept Assay

NCT01507155
View directory record Official record
Conditions
Treatment Resistant Depression, Generalized Anxiety Disorder
Interventions
Genecept Assay
Device
Lead sponsor
Genomind, LLC
Industry
Eligibility
18 Years and older
Enrollment
685 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Chalfont, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 8, 2016 · Synced Oct 21, 2026, 2:24 PM EDT
Completed Not applicable Interventional

Walking or High Intensity Exercise for Anxiety

NCT03819426
View directory record Official record
Conditions
Generalized Anxiety Disorder, Panic Disorder, Social Anxiety
Interventions
Low Intensity Exercise Intervention, High Intensity Intervention
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 65 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 28, 2020 · Synced Oct 21, 2026, 2:24 PM EDT
Recruiting Phase 3 Interventional

Cannabidiol-Assisted Learning for Managing Generalized Anxiety Disorder

NCT07123467
View directory record Official record
Conditions
Generalized Anxiety Disorder (GAD), Anxiety Disorders
Interventions
Low-Dose Cannabidiol, Placebo Matched to Moderate-Dose Cannabidiol, Moderate-Dose Cannabidiol, Placebo Matched to Low-Dose Cannabidiol
Drug
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 45 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 21, 2026 · Synced Oct 21, 2026, 2:24 PM EDT
Terminated Not applicable Interventional

Transcranial Pulse Near-Infrared Light in Generalized Anxiety Disorder: a Placebo-Controlled Study

NCT03420456
View directory record Official record
Conditions
Generalized Anxiety Disorder
Interventions
Transcranial Light Therapy
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 5, 2020 · Synced Oct 21, 2026, 2:24 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Overgeneralization of Conditioned Fear as a Pathogenic Marker of Anorexia Nervosa

NCT02148042
View directory record Official record
Conditions
Anorexia, Generalized Anxiety
Interventions
Not listed
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 12, 2019 · Synced Oct 21, 2026, 2:24 PM EDT
Recruiting Not applicable Interventional

Anxiety Skills Study

NCT07774481
View directory record Official record
Conditions
Anxiety, Anxiety Acute, Anxiety Chronic, Anxiety and Mood Disorders, Social Anxiety Disorder, Panic Disorder (With or Without Agoraphobia), Generalized Anxiety Disorder, Obsessive-Compulsive Disorder, Specific Phobia
Interventions
Cognitive therapy, Behavioral therapy, Mindfulness-based therapy
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 21, 2026, 2:24 PM EDT
Active, not recruiting Not applicable Interventional

Outcomes of Cognitive Behavioral Therapy (CBT) Interventions Provided by Unlicensed Professionals

NCT01075672
View directory record Official record
Conditions
Obsessive Compulsive Disorder, Body Dysmorphic Disorder, Tourette Syndrome, Trichotillomania, Panic Disorder, Social Phobia, Generalized Anxiety Disorder, Depression, Post-Traumatic Stress Disorder, Attention Deficit Hyperactivity Disorder, Eating Disorder, Specific Phobia, General Medical Condition
Interventions
Cognitive behavioral therapy (CBT)
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 23, 2026 · Synced Oct 21, 2026, 2:24 PM EDT
Completed Phase 4 Interventional

Black Cohosh as Alternative Therapy for Treating Menopause-Related Anxiety

NCT00120458
View directory record Official record
Conditions
Generalized Anxiety Disorder, Menopause
Interventions
Black cohosh
Dietary Supplement
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 2, 2010 · Synced Oct 21, 2026, 2:24 PM EDT
Completed Not applicable Interventional

Remember Stuff: A Dyadic-focused Technology to Support Persons With Alzheimer's Disease in the Community

NCT04626804
View directory record Official record
Conditions
Anxiety, Depression, Caregiver Burnout, Anxiety Generalized
Interventions
Remember Stuff: A Dyadic-focused Technology to Support Persons with Alzheimer's Disease in the Community
Other
Lead sponsor
Indiana University
Other
Eligibility
21 Years to 95 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 1, 2023 · Synced Oct 21, 2026, 2:24 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Neurobiology of Generalized Fear-Conditioning & Avoidance in Anxiety Disorders

NCT03033056
View directory record Official record
Conditions
Anxiety Disorders
Interventions
Test of fear conditioning
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 60 Years
Enrollment
208 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 10, 2022 · Synced Oct 21, 2026, 2:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Virtual Reality System for Anxiety and OCD

NCT03636022
View directory record Official record
Conditions
Anxiety, Obsessive-Compulsive Disorder
Interventions
VR System, Control
Other
Lead sponsor
Minnesota HealthSolutions
Industry
Eligibility
7 Years to 17 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 15, 2024 · Synced Oct 21, 2026, 2:24 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Lifestyle Interventions for Generalized Anxiety Disorder

NCT01644812
View directory record Official record
Conditions
Aerobic Exercise, Stretching
Interventions
Aerobic exercise, Stretching
Behavioral
Lead sponsor
Southern Methodist University
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2012
U.S. locations
2
States / cities
Boston, Massachusetts • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 20, 2013 · Synced Oct 21, 2026, 2:24 PM EDT
Terminated Not applicable Interventional

ACT for HIV-Positive Men

NCT06625437
View directory record Official record
Conditions
Stress, Anxiety, Mental Disorder, Distress-based Psychopathology
Interventions
Acceptance and commitment therapy
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older · Male only
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Oct 21, 2026, 2:24 PM EDT
Completed Not applicable Interventional Results available

Exercise Training for the Treatment of Generalized Anxiety Disorder

NCT00953654
View directory record Official record
Conditions
Generalized Anxiety Disorder
Interventions
Strength Training, Endurance Training
Other
Lead sponsor
University of Georgia
Other
Eligibility
18 Years to 39 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 9, 2016 · Synced Oct 21, 2026, 2:24 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Scaling Mental Healthcare in COVID-19 With Voice Biomarkers

NCT04510519
View directory record Official record
Conditions
Major Depressive Disorder, Generalized Anxiety
Interventions
Not listed
Lead sponsor
Kintsugi Mindful Wellness, Inc.
Industry
Eligibility
18 Years to 100 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Sep 30, 2022 · Synced Oct 21, 2026, 2:24 PM EDT
Completed Not applicable Interventional

Clinical Study Assessing a New Scale to Measure Onset of Action in Generalized Anxiety Disorder

NCT00715039
View directory record Official record
Conditions
Anxiety Disorders
Interventions
lorazepam, placebo, paroxetine
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 65 Years
Enrollment
169 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2004
U.S. locations
15
States / cities
Glendale, California • Northridge, California • Orange, California + 10 more
Source: ClinicalTrials.gov public record
Updated Oct 3, 2008 · Synced Oct 21, 2026, 2:24 PM EDT
Terminated Phase 3 Interventional

A 10-week Study Evaluating the Efficacy and Safety of PD 0332334 in Patients With Generalized Anxiety Disorder (1)

NCT00658008
View directory record Official record
Conditions
Generalized Anxiety Disorder
Interventions
PD 0332334, Paroxetine, Placebo
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 65 Years
Enrollment
501 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
45
States / cities
Litchfield Park, Arizona • Costa Mesa, California • Pasadena, California + 37 more
Source: ClinicalTrials.gov public record
Updated Nov 16, 2012 · Synced Oct 21, 2026, 2:24 PM EDT
Completed Phase 2Phase 3 Interventional

St. John's Wort for the Treatment of Generalized Social Anxiety Disorder (GSAD)

NCT00118833
View directory record Official record
Conditions
Anxiety Disorders, Mental Health
Interventions
Hypericum perforatum (St. John's wort)
Drug
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2006
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 26, 2007 · Synced Oct 21, 2026, 2:24 PM EDT
Completed Phase 3 Interventional Results available

Generalized Anxiety Disorder Adjunct Study

NCT00534599
View directory record Official record
Conditions
Anxiety, Anxiety Disorders, Anxiety Neuroses, Anxiety States
Interventions
Placebo, quetiapine fumarate XR
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years to 65 Years
Enrollment
409 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
53
States / cities
Birmingham, Alabama • Little Rock, Arkansas • Beverly Hills, California + 50 more
Source: ClinicalTrials.gov public record
Updated Apr 14, 2011 · Synced Oct 21, 2026, 2:24 PM EDT
Completed Phase 1 Interventional

Acceptance-Based Treatment for Generalized Anxiety Disorder

NCT00073632
View directory record Official record
Conditions
Anxiety Disorders, Generalized Anxiety Disorder
Interventions
Acceptance Based Behavioral Therapy
Behavioral
Lead sponsor
University of Massachusetts, Boston
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2006
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 6, 2013 · Synced Oct 21, 2026, 2:24 PM EDT
Completed Not applicable Interventional Results available

A Comparison Between Cognitive, Behavioral, and Cognitive-Behavioral Therapy for Generalized Anxiety Disorder

NCT00635999
View directory record Official record
Conditions
Generalized Anxiety Disorder
Interventions
Applied relaxation and self-control desensitization, Cognitive therapy (CT), Cognitive-Behavioral Therapy
Behavioral · Other
Lead sponsor
Michelle G. Newman
Other
Eligibility
18 Years to 85 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1991 – 1998
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 25, 2018 · Synced Oct 21, 2026, 2:24 PM EDT