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ClinicalTrials.gov public records Last synced Oct 21, 2026, 2:57 PM EDT

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Showing 49–72 of 302 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Anxiety, Generalized Clear all
Completed Not applicable Interventional

Attention Training for Generalized Anxiety Disorder

NCT00602563
View directory record Official record
Conditions
Generalized Anxiety Disorder
Interventions
AMP, Applied Relaxation (AR), Clinical Monitoring (CM), Combining the AMP and AR
Behavioral
Lead sponsor
San Diego State University
Other
Eligibility
18 Years to 65 Years
Enrollment
193 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2016
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Dec 7, 2016 · Synced Oct 21, 2026, 2:57 PM EDT
Completed Phase 3 Interventional

Safety & Efficacy Study of Quetiapine Fumarate (SEROQUEL®) vs. Placebo in Generalized Anxiety Disorder

NCT00329264
View directory record Official record
Conditions
Generalized Anxiety Disorder
Interventions
Quetiapine fumarate
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years to 65 Years
Enrollment
876 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
58
States / cities
Springdale, Arizona • Little Rock, Arkansas • Encino, California + 55 more
Source: ClinicalTrials.gov public record
Updated Mar 25, 2009 · Synced Oct 21, 2026, 2:57 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

A Phased Clinical Trial of Dietary Supplemental Kava: Kava Pharmacokinetics

NCT03843502
View directory record Official record
Conditions
Pharmacokinetics
Interventions
Kava Dietary Supplement
Drug
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 50 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 12, 2024 · Synced Oct 21, 2026, 2:57 PM EDT
Completed Phase 3 Interventional Results available

Randomized Trial of Adult Participants With Generalized Anxiety Disorder

NCT03829241
View directory record Official record
Conditions
Generalized Anxiety Disorder
Interventions
Troriluzole, Placebo
Drug
Lead sponsor
Biohaven Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
881 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
53
States / cities
Little Rock, Arkansas • Colton, California • Encino, California + 48 more
Source: ClinicalTrials.gov public record
Updated May 8, 2024 · Synced Oct 21, 2026, 2:57 PM EDT
Not yet recruiting Not applicable Interventional

LIFU for Chronic Pain and Generalized Anxiety Disorder

NCT07686354
View directory record Official record
Conditions
Chronic Pain, Generalized Anxiety Disorder
Interventions
Low Intensity Focused Ultrasound
Device
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 21, 2026, 2:57 PM EDT
Completed Phase 2 Interventional

Efficacy, Safety and Tolerability of XBD173 in Patients With Generalized Anxiety Disorder

NCT00108836
View directory record Official record
Conditions
Anxiety Disorders
Interventions
XBD173
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years to 65 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
16
States / cities
Anaheim, California • Los Angeles, California • Newport Beach, California + 13 more
Source: ClinicalTrials.gov public record
Updated May 20, 2010 · Synced Oct 21, 2026, 2:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effects of Emotional Exposure on State Anxiety

NCT03458702
View directory record Official record
Conditions
Generalized Anxiety Disorder
Interventions
YogaFit, Quiet Rest
Behavioral
Lead sponsor
Texas Tech University
Other
Eligibility
18 Years to 25 Years · Female only
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Nov 25, 2019 · Synced Oct 21, 2026, 2:57 PM EDT
Completed Not applicable Interventional

Telephone Acceptance and Commitment Therapy Intervention for Caregivers of Adults With Dementia

NCT04338750
View directory record Official record
Conditions
Anxiety, Anxiety Generalized, Anxiety Disorders and Symptoms, Caregiver Burnout
Interventions
Telephone Acceptance and Commitment Therapy Intervention for Caregivers, minimally-Enhanced Usual Care
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
21 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jul 26, 2022 · Synced Oct 21, 2026, 2:57 PM EDT
Completed Phase 4 Interventional Results available

A Study of Duloxetine in Elderly Generalized Anxiety Disorder

NCT01118780
View directory record Official record
Conditions
Generalized Anxiety Disorder
Interventions
Duloxetine, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
65 Years and older
Enrollment
291 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
10
States / cities
Orlando, Florida • Prairie Village, Kansas • Baltimore, Maryland + 7 more
Source: ClinicalTrials.gov public record
Updated Sep 2, 2013 · Synced Oct 21, 2026, 2:57 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Evaluating the Effects of Stress in Pregnancy

NCT00525226
View directory record Official record
Conditions
Depression, Panic Disorder, Generalized Anxiety Disorder, Post-Traumatic Stress Disorder, Obsessive Compulsive Disorder (OCD)
Interventions
Not listed
Lead sponsor
Emory University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
1,431 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 20, 2013 · Synced Oct 21, 2026, 2:57 PM EDT
Recruiting Not applicable Interventional

Mindful Self-Compassion for Anxiety Disorders and Depression

NCT05671419
View directory record Official record
Conditions
Anxiety Disorders, Generalized Anxiety Disorder, Social Anxiety Disorder, Social Phobia, Panic Disorder, Agoraphobia, Major Depressive Disorder
Interventions
Mindful Self-Compassion
Behavioral
Lead sponsor
Georgetown University
Other
Eligibility
18 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Oct 21, 2026, 2:57 PM EDT
Completed Phase 1Phase 2 Interventional

Therapeutic Massage for Generalized Anxiety Disorder

NCT00515242
View directory record Official record
Conditions
Generalized Anxiety Disorder
Interventions
massage, thermotherapy, relaxing environment
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years to 70 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 13, 2017 · Synced Oct 21, 2026, 2:57 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Generalized Anxiety Disorder and Social Anxiety Disorder: Their Impact on the Processing of Information and Learning

NCT00062517
View directory record Official record
Conditions
Anxiety Disorders
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
18 Years to 50 Years
Enrollment
497 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2016
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 6, 2017 · Synced Oct 21, 2026, 2:57 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Child and Adolescent Anxiety Disorders (CAMS)

NCT00052078
View directory record Official record
Conditions
Anxiety Disorders, Social Phobia, Generalized Anxiety Disorder
Interventions
Sertraline (SRT), Cognitive Behavioral Therapy (CBT), Placebo
Drug · Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
7 Years to 17 Years
Enrollment
488 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2008
U.S. locations
6
States / cities
Los Angeles, California • Baltimore, Maryland • New York, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 19, 2017 · Synced Oct 21, 2026, 2:57 PM EDT
Completed Phase 2Phase 3 Interventional

Improving Quality of Primary Care for Patients With Anxiety and/or Panic Disorders

NCT00102427
View directory record Official record
Conditions
Panic Disorder, Anxiety Disorder
Interventions
Telephone-based collaborative care management
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 64 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2003
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 22, 2014 · Synced Oct 21, 2026, 2:57 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Interactive Voice Based Administration of the GAD 7

NCT04990492
View directory record Official record
Conditions
General Anxiety Disorder
Interventions
Paper GAD 7, Voice Administered GAD 7
Diagnostic Test
Lead sponsor
Oklahoma State University Center for Health Sciences
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 21, 2022 · Synced Oct 21, 2026, 2:57 PM EDT
Terminated Phase 4 Interventional Results available

Open-Label Pilot Study to Examine the Value of Substituting Quetiapine for Benzodiazepines

NCT01244711
View directory record Official record
Conditions
Major Depression, Generalized Anxiety Disorder
Interventions
quetiapine
Drug
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 65 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 3, 2015 · Synced Oct 21, 2026, 2:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Virtual Reality System to Increase Access to Exposure Therapy for Anxiety and OCD

NCT02713516
View directory record Official record
Conditions
Anxiety, Obsessive Compulsive Disorder
Interventions
Virtual Reality
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
7 Years to 12 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 13, 2018 · Synced Oct 21, 2026, 2:57 PM EDT
Recruiting Phase 2 Interventional

Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness

NCT06376734
View directory record Official record
Conditions
Major Depressive Disorder, Obsessive-Compulsive Disorder, Schizophrenia, Generalized Anxiety Disorder, Mood Disorders, Psychiatric Disorder, Mental Disorder, Depression, Anxiety
Interventions
Transcranial magnetic stimulation
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
2
States / cities
Sunnyvale, California • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Oct 21, 2026, 2:57 PM EDT
Active, not recruiting Not applicable Interventional

Text Message Safety Behavior Fading for Pathological Worry

NCT07391020
View directory record Official record
Conditions
Generalized Anxiety Disorder (GAD), Worrying, Anxiety
Interventions
Safety Behavior Fading for Pathological Worry, Progressive Muscle Relaxation (PMR)
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 65 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 21, 2026, 2:57 PM EDT
Completed Not applicable Interventional

Pragmatic Collaborative Care for Cardiac Inpatients With Depression or Anxiety

NCT03118752
View directory record Official record
Conditions
Acute Coronary Syndrome, Heart Failure, Depression, Generalized Anxiety Disorder, Panic Disorder
Interventions
Collaborative Care
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
290 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
3
States / cities
Boston, Massachusetts • Salem, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 13, 2024 · Synced Oct 21, 2026, 2:57 PM EDT
Active, not recruiting Not applicable Interventional

MBSR Mechanisms in GAD

NCT05064813
View directory record Official record
Conditions
Generalized Anxiety Disorder
Interventions
Mindfulness Based Stress Reduction MBSR Intervention, Stress Education Control Condition (SE)
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 50 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 10, 2026 · Synced Oct 21, 2026, 2:57 PM EDT
Completed Phase 3 Interventional Results available

Treatment Effects of Escitalopram (Lexapro®) on Generalized Anxiety Disorder in Patients With HIV and AIDS

NCT00887679
View directory record Official record
Conditions
Anxiety Disorders, HIV Infections
Interventions
Escitalopram
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 31, 2014 · Synced Oct 21, 2026, 2:57 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Anti-anxiety Biotics for Breast Cancer Survivors

NCT04784182
View directory record Official record
Conditions
Anxiety Generalized, Breast Cancer Female
Interventions
probiotic plus prebiotic supplement, placebo
Dietary Supplement
Lead sponsor
Auburn University
Other
Eligibility
50 Years and older · Female only
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Auburn, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 24, 2023 · Synced Oct 21, 2026, 2:57 PM EDT