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Showing 1–24 of 46 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Anxiety, Preoperative Clear all
Completed No phase listed Observational Accepts healthy volunteers

Preoperative Hip Knee Anxiety Sleep Study

NCT04180527
View directory record Official record
Conditions
Anxiety, Sleep, Surgery
Interventions
Not listed
Lead sponsor
Henry Ford Health System
Other
Eligibility
Not listed
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 14, 2022 · Synced Jul 22, 2026, 10:30 PM EDT
Recruiting Not applicable Interventional

Pre-Operative Guided Meditation to Reduce Pre-Operative Anxiety in Patients Undergoing Cancer-Directed Surgery

NCT06949943
View directory record Official record
Conditions
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
Interventions
Behavioral Intervention, Electronic Health Record Review, Survey Administration
Behavioral · Other
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Jul 22, 2026, 10:30 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparison of Usual Care and Distraction (Tablet) in Children 3-5 Years Old

NCT05368961
View directory record Official record
Conditions
Anxiety
Interventions
Distraction, Usual care
Behavioral · Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
3 Years to 5 Years
Enrollment
137 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 31, 2024 · Synced Jul 22, 2026, 10:30 PM EDT
Completed Not applicable Interventional

Impact of a Breath-controlled Video Game App

NCT04000646
View directory record Official record
Conditions
Anxiety Acute
Interventions
standard care, breath-controlled app
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
3 Years to 8 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 28, 2021 · Synced Jul 22, 2026, 10:30 PM EDT
Completed Not applicable Interventional

Preoperative 3D Models and Shared Decision-making

NCT06625008
View directory record Official record
Conditions
Colorectal Cancer, Shared Decision Making, Anxiety, Informed Consent
Interventions
3D-printed model
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 2, 2024 · Synced Jul 22, 2026, 10:30 PM EDT
Terminated Phase 1Phase 2 Interventional Results available

Music vs Midazolam During Preop Nerve Block Placement - Part 2 Study On Anxiolytic Options Before Peripheral Nerve Blocks

NCT05610969
View directory record Official record
Conditions
Peripheral Nerve Block, Anxiety, Preoperative Anxiety
Interventions
Music, Midazolam
Other · Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 13, 2025 · Synced Jul 22, 2026, 10:30 PM EDT
Completed Not applicable Interventional

The Effect of Mirror Education for Women Undergoing Mastectomy

NCT01642628
View directory record Official record
Conditions
Emotional Distress, Anxiety, Depression
Interventions
Mirror Education
Other
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years and older · Female only
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 31, 2014 · Synced Jul 22, 2026, 10:30 PM EDT
Enrolling by invitation Not applicable Interventional

Impact of Immersive Video Education on Cardiothoracic Surgery Anxiety and Outcomes

NCT07222839
View directory record Official record
Conditions
Anxiety
Interventions
Visually Immersive Video, Standard of Care
Behavioral
Lead sponsor
Baptist Health South Florida
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Jul 22, 2026, 10:30 PM EDT
Completed Not applicable Interventional Results available

Guided Meditation to Decrease Perioperative Anxiety and Increase Patient Intraoperative Compliance in Vascular Surgery

NCT05837481
View directory record Official record
Conditions
Peripheral Vascular Disease
Interventions
Meditation
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
4
States / cities
Boston, Massachusetts • Newton, Massachusetts • Salem, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 15, 2024 · Synced Jul 22, 2026, 10:30 PM EDT
Completed Not applicable Interventional

A Study of the Effects of Lavender Aromatherapy on Preoperative Anxiety in Breast Surgery Patients

NCT03445130
View directory record Official record
Conditions
Anxiety
Interventions
Lavandula Angustifolia oil (LO), Michelia Alba Leaf oil (MA), Almond oil (AO), Water
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 100 Years · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 17, 2022 · Synced Jul 22, 2026, 10:30 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Implementing a Paced Deep Breathing Module to Decrease Preoperative Anxiety in Gynecological Surgery Patients

NCT03078790
View directory record Official record
Conditions
Anxiety
Interventions
iPad
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 15, 2019 · Synced Jul 22, 2026, 10:30 PM EDT
Completed Not applicable Interventional

Use of Handheld Audiovisual Devices to Treat Pediatric Preoperative Anxiety

NCT02286674
View directory record Official record
Conditions
Pediatric Preoperative Anxiety
Interventions
Tablet (Audio/Visual Device)
Other
Lead sponsor
McLaren Health Care
Other
Eligibility
2 Years to 12 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 24, 2022 · Synced Jul 22, 2026, 10:30 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of High-quality Pre-operative Videos on Patient Anxiety Levels Prior to Ambulatory Hand Surgery

NCT04424810
View directory record Official record
Conditions
Anxiety, Carpal Tunnel Syndrome, Trigger Finger, Engagement, Patient, Pain
Interventions
High-quality, physician created video, Standard of care
Other
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
167 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Sep 4, 2021 · Synced Jul 22, 2026, 10:30 PM EDT
Completed Not applicable Interventional

Preoperative Guided Imagery in Patients Undergoing Urologic Surgery

NCT05072639
View directory record Official record
Conditions
Urologic Cancer
Interventions
Guided Meditation
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
123 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 21, 2021 · Synced Jul 22, 2026, 10:30 PM EDT
Completed Not applicable Interventional

Music Listening on Preoperative Anxiety in Female Pelvic Medicine and Reconstructive Surgery

NCT03651310
View directory record Official record
Conditions
Preoperative Anxiety
Interventions
Music Listening Group
Other
Lead sponsor
Loyola University
Other
Eligibility
18 Years and older · Female only
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Maywood, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 4, 2019 · Synced Jul 22, 2026, 10:30 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

A Mobile Application for Child-focused Perioperative Education

NCT06054282
View directory record Official record
Conditions
Preoperative Anxiety
Interventions
"Ready for Tonsillectomy" educational mobile application
Behavioral
Lead sponsor
Children's Healthcare of Atlanta
Other
Eligibility
5 Years to 13 Years
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 21, 2024 · Synced Jul 22, 2026, 10:30 PM EDT
Completed Not applicable Interventional Results available

Preoperative Acupuncture for Total Knee or Hip Arthroplasty

NCT06099223
View directory record Official record
Conditions
Knee Arthropathy, Hip Arthropathy, Anxiety
Interventions
Acupuncture needles
Device
Lead sponsor
Hartford Hospital
Other
Eligibility
18 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 25, 2025 · Synced Jul 22, 2026, 10:30 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Preparing Children for Anesthesia With an Educational Pop-Up Book

NCT04796077
View directory record Official record
Conditions
Pediatric Preoperative Anxiety, Pediatric Coping
Interventions
Pop-Up Book
Other
Lead sponsor
Children's Healthcare of Atlanta
Other
Eligibility
5 Years to 12 Years
Enrollment
148 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Duluth, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 11, 2021 · Synced Jul 22, 2026, 10:30 PM EDT
Completed Phase 3 Interventional Results available

A Comparison of Midazolam and Zolpidem as Oral Premedication in Children

NCT02096900
View directory record Official record
Conditions
Parental/Caregiver Anxiety, Child's Anxiety
Interventions
zolpidem, Midazolam
Drug
Lead sponsor
Loma Linda University
Other
Eligibility
2 Years to 9 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Mar 13, 2019 · Synced Jul 22, 2026, 10:30 PM EDT
Terminated Phase 4 Interventional Results available

Cranial Electro Therapy Stimulation in Reducing Perioperative Anxiety

NCT00928772
View directory record Official record
Conditions
Anxiety
Interventions
CRANIAL ELECTROTHERAPY (Alpha Stim) + SHAM MIDAZOLAM, MIDAZOLAM + SHAM ELECTRODES SIMULATING CRANIAL ELECTROTHERAPY, NO SEDATION WITH SHAM CRANIAL ELECTROSTIMULATION AND PLACEBO VERSED
Device · Drug · Other
Lead sponsor
University of Oklahoma
Other
Eligibility
50 Years to 90 Years
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 19, 2017 · Synced Jul 22, 2026, 10:30 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of an Educational Nail Biopsy Video on Pre-operative Anxiety, Health Literacy, and Patient Satisfaction

NCT06274775
View directory record Official record
Conditions
Anxiety, Literacy, Satisfaction, Patient
Interventions
Educational Video
Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Jul 22, 2026, 10:30 PM EDT
Completed Phase 2 Interventional

A GameBoy as a Distraction Before Surgery in Children

NCT00176670
View directory record Official record
Conditions
Anxiety
Interventions
midazolam or GameBoy or parental presence
Drug
Lead sponsor
University of Medicine and Dentistry of New Jersey
Other
Eligibility
4 Years to 16 Years
Enrollment
158 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 5, 2016 · Synced Jul 22, 2026, 10:30 PM EDT
Completed Phase 1 Interventional

Massage Therapy and Port-a-Catheter Insertion

NCT00991770
View directory record Official record
Conditions
Cancer, Anxiety, Pain, Surgery
Interventions
Massage Therapy, Attention Control
Other
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 6, 2011 · Synced Jul 22, 2026, 10:30 PM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

Virtual Reality to Reduce Pre-Operative Anxiety

NCT04268914
View directory record Official record
Conditions
Virtual Reality, Augmented Reality, IV Stick, Mask Induction, Ambulatory Surgery, Pain, Anxiety
Interventions
Oculus Go VR, Mira Prism VR
Device
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
10 Years to 21 Years
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 26, 2023 · Synced Jul 22, 2026, 10:30 PM EDT