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ClinicalTrials.gov public records Last synced Oct 24, 2026, 4:42 AM EDT

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Showing 1–24 of 92 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Anxiety Acute Clear all
Not yet recruiting Not applicable Interventional

Therapeutic Benefits of Pareidolia in Acute Traumatic Brain Injury Patients

NCT07867119
View directory record Official record
Conditions
Traumatic Brain Injuries
Interventions
Therapeutic Benefits of Pareidolia, Active Comparator #1
Behavioral
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 9, 2026 · Synced Oct 24, 2026, 4:42 AM EDT
Not listed Phase 4 Interventional

Acute and Long-Term Antidepressant Treatment Success in Adolescents With Anxiety (AtLAS-A)

NCT04245436
View directory record Official record
Conditions
Anxiety, Depressive Symptoms
Interventions
Duloxetine, Escitalopram
Drug
Lead sponsor
University of Cincinnati
Other
Eligibility
12 Years to 17 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 29, 2024 · Synced Oct 24, 2026, 4:42 AM EDT
Enrolling by invitation Not applicable Interventional

VR for Steroid Joint Injections - Feasibility

NCT07778069
View directory record Official record
Conditions
Acute Pain, Procedural Anxiety, Juvenile Idiopahtic Arthritis
Interventions
VR-PAT
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
5 Years to 17 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Oct 24, 2026, 4:42 AM EDT
Completed Not applicable Interventional Results available

Researching Resiliency in Stressful Experiences (RISE) Program for Men Leaving Incarceration

NCT04785677
View directory record Official record
Conditions
Stress Disorders, Traumatic, Stress Disorders, Traumatic, Acute, Depressive Symptoms, Anxiety, Substance Use, Aggression, Coping Skills, Impulsive Behavior, Housing Problems, Recidivism, Stress, Occupational Stress, Psychological Distress
Interventions
Resiliency in Stressful Experiences (RISE) Program
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
403 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Aug 28, 2026 · Synced Oct 24, 2026, 4:42 AM EDT
Completed Not applicable Interventional

Calming Alternatives Learned During MRI-Guided Breast Biopsy

NCT03877146
View directory record Official record
Conditions
Breast Cancer, Breast Pain, Pain, Acute, Anxiety, Coping Skills, Self Efficacy
Interventions
Controlled Breathing Intervention
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older · Female only
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 25, 2020 · Synced Oct 24, 2026, 4:42 AM EDT
Completed Not applicable Interventional

Aromatherapy and Essential Oils in Improving Insomnia and Other Symptoms in Patients With Newly Diagnosed Acute Leukemia Undergoing Chemotherapy

NCT02445378
View directory record Official record
Conditions
Acute Leukemia, Anorexia, Anxiety, Depression, Dyspnea, Insomnia, Nausea, Pain
Interventions
Aromatherapy and Essential Oils, Placebo, Questionnaire Administration
Procedure · Other
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
Not listed
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 5, 2019 · Synced Oct 24, 2026, 4:42 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

fMRI Study Examining Effects of D-cycloserine in Specific Phobia

NCT00591825
View directory record Official record
Conditions
Phobias
Interventions
D-cycloserine, Placebo
Drug
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 55 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2012
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jun 5, 2017 · Synced Oct 24, 2026, 4:42 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Healthy Children and Virtual Reality Mediation of Simulated Pain

NCT06854991
View directory record Official record
Conditions
Acute Pain, Experimental Pain in Healthy Human Participants, Children, Adolescents
Interventions
Active VR-PAT, Passive VR-PAT, iPad
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
6 Years to 17 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Oct 24, 2026, 4:42 AM EDT
Withdrawn Not applicable Interventional

Canine-Assisted ANxiety Reduction IN Emergency Care IV

NCT04287452
View directory record Official record
Conditions
Anxiety Acute, Chronic Pain
Interventions
Control, Dog Therapy
Other
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jul 20, 2023 · Synced Oct 24, 2026, 4:42 AM EDT
Terminated Not applicable Interventional Results available

The Use of Clonidine in Pain and Anxiety Associated With Acute Burn Injury in Children

NCT00580151
View directory record Official record
Conditions
Pain, Anxiety
Interventions
clonidine, placebo
Drug
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
4 Years to 20 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2014
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 23, 2015 · Synced Oct 24, 2026, 4:42 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Lorazepam-Induced Toxicity in the Aged

NCT00044642
View directory record Official record
Conditions
Anxiety Disorders, Generalized Anxiety Disorder
Interventions
Lorazepam
Drug
Lead sponsor
Nathan Kline Institute for Psychiatric Research
Other
Eligibility
60 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2007
U.S. locations
2
States / cities
New York, New York • Orangeburg, New York
Source: ClinicalTrials.gov public record
Updated Dec 6, 2013 · Synced Oct 24, 2026, 4:42 AM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

Use Muscadine Wine Nutraceuticals to Improve Brain Health, Cognition, and Mental Health

NCT05541887
View directory record Official record
Conditions
Cognitive Performance, Memory, Mood, Anxiety
Interventions
Muscadine Wine Polyphenol, Placebo
Other
Lead sponsor
University of Florida
Other
Eligibility
50 Years to 65 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 24, 2026, 4:42 AM EDT
Enrolling by invitation Not applicable Interventional

Little NIRVANA for Pediatric Pain and Anxiety

NCT06795126
View directory record Official record
Conditions
Acute Pain, Procedural Anxiety, Pediatric ALL, Emergency Medicine, IV Access
Interventions
Little NIRVANA
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
2 Years to 8 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Oct 24, 2026, 4:42 AM EDT
Recruiting Phase 3 Interventional

Morphine or Ketamine for Analgesia

NCT06835504
View directory record Official record
Conditions
Abdominal Pain, Isolated Extremity Fracture, Pain, Pediatrics
Interventions
Ketamine hydrochloride, Morphine sulphate
Drug
Lead sponsor
Columbia University
Other
Eligibility
6 Years to 17 Years
Enrollment
1,010 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
8
States / cities
Los Angeles, California • Sacramento, California • Wilmington, Delaware + 5 more
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Oct 24, 2026, 4:42 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Acute Effects of Cannabigerol

NCT05257044
View directory record Official record
Conditions
Focus: To Examine Acute Effects of CBG on Anxiety, Stress, and Cognition
Interventions
Cannabigerol, Placebo
Drug · Other
Lead sponsor
Washington State University
Other
Eligibility
21 Years and older
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Pullman, Washington
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Oct 24, 2026, 4:42 AM EDT
Recruiting Not applicable Interventional

The Use of a Comfort Tote to Improve Recovery in Pediatric and Adolescent Patients After Surgery

NCT07632833
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis, Postoperative Pain, Acute, Postoperative Nausea and Vomiting, Anxiety
Interventions
The Therapeutic Comfort Tote, The Modified Comfort Tote
Other
Lead sponsor
Columbia University
Other
Eligibility
12 Years to 21 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 9, 2026 · Synced Oct 24, 2026, 4:42 AM EDT
Not yet recruiting Not applicable Interventional

Weighted Blankets for Pain and Anxiety in Adult Trauma Patients

NCT07802171
View directory record Official record
Conditions
Traumatic Injury, Acute Pain
Interventions
Weighted Blanket, Standard Hospital Blanket
Device
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 89 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Oct 24, 2026, 4:42 AM EDT
Completed Not applicable Interventional

Acute Psychiatric Care at Home for Lower-risk Patients With Acute Psychiatric Illness Who Require Inpatient Care

NCT07364825
View directory record Official record
Conditions
Psychosis, Anxiety, Depression, Behavioral and Psychiatric Symptoms of Dementia
Interventions
Behavioral Health Home Hospital
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
4
States / cities
Belmont, Massachusetts • Boston, Massachusetts • Jamaica Plain, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Oct 24, 2026, 4:42 AM EDT
Active, not recruiting No phase listed Observational

Neuropsychiatric Post-Acute Sequelae of SARS-CoV-2 (PASC) Using TSPO Positron Emission Tomography (PET) and MRI

NCT05615415
View directory record Official record
Conditions
Neuropsychiatric Post-Acute Sequelae of SARS-CoV-2 Infection
Interventions
PET Tracer, MRI Tracer, 3T PET/MRI
Drug · Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 50 Years
Enrollment
30 participants
Timeline
2022 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 24, 2026, 4:42 AM EDT
Active, not recruiting Phase 3 Interventional Accepts healthy volunteers

REmotely-delivered Supportive Programs for Improving Surgical Pain and disTrEss

NCT05625360
View directory record Official record
Conditions
Postoperative Pain, Acute, Postoperative Depression, Anxiety, Sleep Disturbance, Malignant Female Reproductive System Neoplasm
Interventions
eHealth Mindful Movement and Breathing, Life Impacts Reflection, PROMIS Questionnaires
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older · Female only
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
2
States / cities
Charlotte, North Carolina • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 24, 2026 · Synced Oct 24, 2026, 4:42 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

COVID-19-Related Health and Practices Among Dental Hygienists

NCT04542915
View directory record Official record
Conditions
SARS-CoV Infection, Anxiety, Depression, Occupational Problems, Severe Acute Respiratory Syndrome, Coronavirus Infection
Interventions
No intervention
Other
Lead sponsor
American Dental Association
Other
Eligibility
18 Years and older
Enrollment
6,976 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 16, 2021 · Synced Oct 24, 2026, 4:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Yogic Breathing and Guided Meditation for Long Covid Symptoms

NCT05139979
View directory record Official record
Conditions
COVID-19, Stress, Shortness of Breath
Interventions
Breathing and Wellness Webinar, Routine Daily Activity
Behavioral · Other
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 70 Years
Enrollment
189 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 6, 2025 · Synced Oct 24, 2026, 4:42 AM EDT
Completed Not applicable Interventional

Stroke and Anxiety Reduction

NCT06013982
View directory record Official record
Conditions
Acute Stroke
Interventions
Anxiety Reduction Bundle
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 89 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 18, 2025 · Synced Oct 24, 2026, 4:42 AM EDT
Completed Not applicable Interventional

Impact of a Breath-controlled Video Game App

NCT04000646
View directory record Official record
Conditions
Anxiety Acute
Interventions
standard care, breath-controlled app
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
3 Years to 8 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 29, 2021 · Synced Oct 24, 2026, 4:42 AM EDT