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ClinicalTrials.gov public records Last synced Oct 25, 2026, 4:24 AM EDT

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Showing 889–912 of 1,311 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Anxiety Depression Clear all
Active, not recruiting Not applicable Interventional

Preventing Anxiety and Depression in Older Hispanics

NCT03870360
View directory record Official record
Conditions
Depression, Anxiety
Interventions
HOLA Component 1, HOLA Component 2, HOLA Component 3, HOLA Component 4, Healthy lifestyles education program
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
60 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 15, 2026 · Synced Oct 25, 2026, 4:24 AM EDT
Completed Not applicable Interventional

Chatbot for Depression, Anxiety, and Eating Disorders

NCT06013137
View directory record Official record
Conditions
Depression, Anxiety, Eating Disorders
Interventions
Therabot
Other
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Jun 27, 2025 · Synced Oct 25, 2026, 4:24 AM EDT
Recruiting No phase listed Observational

Retrospective Analyses of TrakStar Database

NCT06917339
View directory record Official record
Conditions
Depression, Obsessive-Compulsive Disorder, Anxiety Depression
Interventions
NeuroStar Advanced TMS Therapy System
Device
Lead sponsor
Neuronetics
Other
Eligibility
5 Years to 120 Years
Enrollment
156,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2035
U.S. locations
1
States / cities
Malvern, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 9, 2026 · Synced Oct 25, 2026, 4:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Peer-led Group Intervention for Coping With Disaster

NCT03907995
View directory record Official record
Conditions
Anxiety Disorder, PTSD, Depressive Symptoms, Anger, Depressive Disorder
Interventions
Cognitive Behavioral Therapy
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 27, 2020 · Synced Oct 25, 2026, 4:24 AM EDT
Completed Not applicable Interventional

Clinical Study Evaluating Effects of Pharmacogenetic-guided vs Standard-of-Care Treatment on Depression and/or Anxiety

NCT02878928
View directory record Official record
Conditions
Depression, Anxiety
Interventions
IDgenetix Neuropsychiatric Test Panel
Genetic
Lead sponsor
AltheaDx
Industry
Eligibility
18 Years and older
Enrollment
579 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
17
States / cities
Rolling Hills, California • San Diego, California • Torrance, California + 13 more
Source: ClinicalTrials.gov public record
Updated Dec 19, 2016 · Synced Oct 25, 2026, 4:24 AM EDT
Recruiting Not applicable Interventional

Postpartum Care in the NICU (PeliCaN) Transitions

NCT06521398
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Premature Birth, Postpartum Depression, Postpartum Anxiety
Interventions
Doula Support
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
16 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Oct 25, 2026, 4:24 AM EDT
Not listed Phase 2 Interventional

A Dyadic Approach to Perinatal Depression in Primary Care: Maternal Infant and Dyadic Care

NCT04998721
View directory record Official record
Conditions
Depression, Postpartum, Efficacy, Self, Anxiety
Interventions
Promoting First Relationships-Brief, Perinatal Collaborative Care
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 22, 2023 · Synced Oct 25, 2026, 4:24 AM EDT
Completed Not applicable Interventional

Efficacy Evaluation of a Unified Transdiagnostic Treatment for Anxiety Disorders

NCT01243606
View directory record Official record
Conditions
Anxiety Disorders, Mood Disorders
Interventions
Single Diagnosis Treatment Protocol, Unified Protocol (UP)
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 9, 2017 · Synced Oct 25, 2026, 4:24 AM EDT
Completed Not applicable Interventional Results available

Improving Obesity Self-Care Among Mentally Ill Veterans

NCT02642536
View directory record Official record
Conditions
Anxiety, Depression, PTSD, Obesity
Interventions
MH MOVE, Enhanced Usual Care
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 22, 2018 · Synced Oct 25, 2026, 4:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Strong People Strength Training Study

NCT04203563
View directory record Official record
Conditions
Heart Diseases, Cardiovascular Diseases, Diabetes, Sedentary Lifestyle, Overweight and Obesity, Depression, Anxiety, Stress, Fatigue
Interventions
Strong People Strength Training
Behavioral
Lead sponsor
Cornell University
Other
Eligibility
50 Years to 100 Years
Enrollment
167 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
6
States / cities
Choteau, Montana • Fort Benton, Montana • Glasgow, Montana + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 21, 2020 · Synced Oct 25, 2026, 4:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Maine Implementation Study - Phase III

NCT02229305
View directory record Official record
Conditions
Anxiety, Trauma, Depression, Problem Behavior
Interventions
Usual Care Treatment, Modular Approach to Therapy for Children
Behavioral
Lead sponsor
Harvard University
Other
Eligibility
6 Years to 15 Years
Enrollment
235 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 1, 2014 · Synced Oct 25, 2026, 4:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Community-Led Action Research in Oncology: Improving Symptom Management

NCT03208816
View directory record Official record
Conditions
Chemotherapy-induced Neutropenia, Chemotherapy-induced Nausea and Vomiting, Anxiety, Depression, Fatigue, Neoplasms
Interventions
symptom management program for chemotherapy patients
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Mar 27, 2018 · Synced Oct 25, 2026, 4:24 AM EDT
Completed Not applicable Interventional

Pilot Study of a CF-specific CBT Intervention for Adolescents

NCT05271643
View directory record Official record
Conditions
Cystic Fibrosis, Depression, Anxiety
Interventions
Cognitive Behavioral Therapy (CBT)
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
12 Years to 17 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
3
States / cities
Kansas City, Kansas • Boston, Massachusetts • New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 25, 2026, 4:24 AM EDT
Active, not recruiting Not applicable Interventional

Wellness App for Sleep Disturbance in Hematological Cancer Patients

NCT05294991
View directory record Official record
Conditions
Cancer, Sleep Disturbance, Anxiety, Depression, Inflammation, Fatigue
Interventions
Wellness app intervention #1, Wellness app intervention #2
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
276 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
3
States / cities
Phoenix, Arizona • Winston-Salem, North Carolina • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Oct 25, 2026, 4:24 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Assessing the Impact of Isha Kriya Meditation on Anxiety and Depression - a Pilot Study

NCT05065476
View directory record Official record
Conditions
Anxiety, Depression
Interventions
Not listed
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 70 Years
Enrollment
267 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 5, 2022 · Synced Oct 25, 2026, 4:24 AM EDT
Completed No phase listed Observational

Identification of Anxiety and Depression in Adolescents/Young Adults (AYA) With Cancer

NCT04589052
View directory record Official record
Conditions
Cancer, Depression, Anxiety
Interventions
Not listed
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
15 Years to 29 Years
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 31, 2024 · Synced Oct 25, 2026, 4:24 AM EDT
Completed Phase 1Phase 2 Interventional

Behavioral Treatments for Anxiety and Depression in Veterans With Parkinson's Disease

NCT01323699
View directory record Official record
Conditions
Parkinson Disease, Anxiety, Depression
Interventions
Cognitive Behavioral Therapy
Behavioral
Lead sponsor
Michael E. DeBakey VA Medical Center
Federal
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 1, 2013 · Synced Oct 25, 2026, 4:24 AM EDT
Completed Not applicable Interventional

Microcurrent Neurofeedback as an Adjunct to Standard Care for Substance Use Disorders

NCT07737652
View directory record Official record
Conditions
Depression, Anxiety, Substance Use Disorder (SUD), Post Traumatic Stress Disorder
Interventions
Microcurrent Neurofeedback (MCN), Standard Care for Substance Use Disorder
Device · Behavioral
Lead sponsor
University of Alabama, Tuscaloosa
Other
Eligibility
18 Years to 65 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Tuscaloosa, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Oct 25, 2026, 4:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Implementing and Evaluating an Internet-based Cognitive Behavior Therapy Intervention in School Settings

NCT04928001
View directory record Official record
Conditions
Depression Anxiety and Co-occurring Rural Youth
Interventions
internet based iCBT program, Youth Thrive
Other
Lead sponsor
Montana State University
Other
Eligibility
13 Years to 19 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Bozeman, Montana
Source: ClinicalTrials.gov public record
Updated Jan 30, 2025 · Synced Oct 25, 2026, 4:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

StriveWeekly Online Mental Health Trial Post-pandemic

NCT04927845
View directory record Official record
Conditions
Anxiety, Depressive Symptoms, Stress, Emotional
Interventions
StriveWeekly
Behavioral
Lead sponsor
Harvard University
Other
Eligibility
16 Years and older
Enrollment
538 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 3, 2024 · Synced Oct 25, 2026, 4:24 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Strengthening Community Mental Health

NCT06093737
View directory record Official record
Conditions
Mental Health, Emotional Wellbeing, Anxiety, Depression, Stress, Coping, Perceived Stress, Perceived Social Support
Interventions
COPE: Communities Organizing for Power through Empathy
Behavioral
Lead sponsor
Louisiana State University and A&M College
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Oct 23, 2023 · Synced Oct 25, 2026, 4:24 AM EDT
Completed Not applicable Interventional Results available

Perioperative Mental Health in Orthopedic Surgery

NCT05697835
View directory record Official record
Conditions
Orthopedic Surgery, Older Adults, Depression, Anxiety
Interventions
Behavioral activation, Medication optimzation, Care as usual
Behavioral · Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
60 Years and older
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 9, 2026 · Synced Oct 25, 2026, 4:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

WILD 5 Wellness, A 30-Day Intervention

NCT03328520
View directory record Official record
Conditions
Anxiety, Depression, Cognitive Functioning, Wellness
Interventions
WILD 5 Wellness Intervention
Behavioral
Lead sponsor
Beloit College
Other
Eligibility
17 Years and older
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Beloit, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 26, 2018 · Synced Oct 25, 2026, 4:24 AM EDT
Completed Not applicable Interventional Results available

Self-Defense Training in Women With Trauma

NCT01380379
View directory record Official record
Conditions
Depression, Anxiety, Stress Disorders, Post-Traumatic
Interventions
Life skills and self-defense training
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
21 Years to 65 Years · Female only
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Feb 1, 2017 · Synced Oct 25, 2026, 4:24 AM EDT