Independent directory Public ClinicalTrials.gov records United States
Clinical Trials Finder
Objective public record navigation
Search Results

Search by objective public record fields.

Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.

Clear filters
ClinicalTrials.gov public records Last synced Jun 10, 2026, 1:35 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 316 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Anxiety Disorder Generalized Clear all
Withdrawn Phase 3 Interventional

6-Month Open-Label Safety Study Of PD 0332334 In Elderly Patients With Generalized Anxiety Disorder (GAD)

NCT00738738
View directory record Official record
Conditions
Generalized Anxiety Disorder
Interventions
PD-0332334
Drug
Lead sponsor
Pfizer
Industry
Eligibility
65 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
2
States / cities
Orlando, Florida • Prairie Village, Kansas
Source: ClinicalTrials.gov public record
Updated Dec 2, 2012 · Synced Jun 10, 2026, 1:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Transdisciplinary Studies of CBT for Anxiety in Youth: Child Anxiety Treatment Study

NCT00774150
View directory record Official record
Conditions
Generalized Anxiety Disorder, Separation Anxiety Disorder, Social Phobia
Interventions
Cognitive Behavioral Therapy, Client Centered Therapy
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
9 Years to 14 Years
Enrollment
194 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2014
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 17, 2014 · Synced Jun 10, 2026, 1:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Digital Data in Mental Health Therapy

NCT04011540
View directory record Official record
Conditions
Depressive Symptoms, Anxiety Generalized
Interventions
Digital data
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 80 Years
Enrollment
115 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 27, 2024 · Synced Jun 10, 2026, 1:35 PM EDT
Completed Phase 3 Interventional

Safety & Efficacy Study of Quetiapine Fumarate (SEROQUEL®) vs. Placebo & Active Control in Generalized Anxiety Disorder

NCT00329446
View directory record Official record
Conditions
Generalized Anxiety Disorder
Interventions
Quetiapine Fumarate, Escitalopram oxylate
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years to 65 Years
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
63
States / cities
Birmingham, Alabama • Scottsdale, Arizona • Little Rock, Arkansas + 60 more
Source: ClinicalTrials.gov public record
Updated Mar 24, 2009 · Synced Jun 10, 2026, 1:35 PM EDT
Completed Not applicable Interventional Results available

Stepped-Care Cognitive-Behavioral Treatment for Youth With ASD and Anxiety

NCT03720795
View directory record Official record
Conditions
Cognitive Behavioral Therapy, Autism Spectrum Disorder, Anxiety Disorders, Obsessive-Compulsive Disorder, Social Anxiety Disorder, Generalized Anxiety Disorder, Specific Phobia
Interventions
Stepped Care CBT
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
4 Years to 14 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 14, 2025 · Synced Jun 10, 2026, 1:35 PM EDT
Terminated Phase 3 Interventional

A 52-Week Open-Label Safety Study of PD 0332334 in Subjects With Generalized Anxiety Disorder (GAD)

NCT00735267
View directory record Official record
Conditions
Generalized Anxiety Disorder
Interventions
PD 0332334
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 65 Years
Enrollment
468 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
93
States / cities
Birmingham, Alabama • Litchfield Park, Arizona • Arcadia, California + 79 more
Source: ClinicalTrials.gov public record
Updated Nov 15, 2012 · Synced Jun 10, 2026, 1:35 PM EDT
Completed Not applicable Interventional

Adaptation and Feasibility of the Community-Based Anxiety Program Tailored for Autism (CAPTA)

NCT06046170
View directory record Official record
Conditions
Anxiety, Autism Spectrum Disorder, Separation Anxiety, Generalized Anxiety Disorder, Social Anxiety Disorder of Childhood
Interventions
Cognitive Behavioral Therapy, Treatment as Usual
Behavioral · Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
7 Years to 17 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
3
States / cities
Baltimore, Maryland • Philadelphia, Pennsylvania • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Jun 10, 2026, 1:35 PM EDT
Completed Phase 4 Interventional Results available

Combination of Paroxetine CR and Quetiapine for the Treatment of Refractory Generalized Anxiety Disorder

NCT00113295
View directory record Official record
Conditions
Anxiety Disorder
Interventions
Continued Paroxetine CR, Quetiapine, Placebo
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 72 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
2
States / cities
Boston, Massachusetts • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 22, 2014 · Synced Jun 10, 2026, 1:35 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research

NCT04806620
View directory record Official record
Conditions
Post-Acute COVID-19 Syndrome, ME/CFS, Rheumatic Arthritis, Juvenile Rheumatoid Arthritis (JRA), Psoriatic Arthritis (PsA), Ankylosing Spondylitis (AS), Autoimmune Encephalitis, Celiac Disease, Celiac Disease in Children, Chronic Lyme Disease, Post-treatment Lyme Disease Syndrome, Crohn's Disease, Dysautonomia, Anorexia Nervosa, Bulimia Nervosa, ARFID, Avoidant / Restrictive Food Intake Disorder, Ehlers Danlos Syndrome, Endometriosis, Fibromyalgia (FM), Long COVID, Lupus, Migraines, Mast Cell Activation Syndrome, Multiple Sclerosis, Myalgic Encephalomyelitis (ME), Myasthenia Gravis, Generalized, Myasthenia Gravis in Children, Narcolepsy, Obsessive Compulsive Disorder (OCD), PANDAS, Pediatric Acute-onset Neuropsychiatric Syndrome (PANS), POTS - Postural Orthostatic Tachycardia Syndrome, General Anxiety Disorder, Social Anxiety Disorder, PTSD - Post Traumatic Stress Disorder, Psoriasis, Traumatic Brain Injury, Tourette's Syndrome, Inflammatory Bowel Disease (IBD), Autoimmune Diseases, Neurological Diseases or Conditions, Psychiatric Disorder, Sjogren's Syndrome, Ulcerative Colitis and Crohn's Disease
Interventions
Not listed
Lead sponsor
Brain Inflammation Collaborative
Other
Eligibility
2 Years and older
Enrollment
10,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2030
U.S. locations
1
States / cities
Delafield, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Jun 10, 2026, 1:35 PM EDT
Terminated Phase 2 Interventional Results available

POC Study in Partially Responsive Generalized Anxiety Disorder

NCT02310568
View directory record Official record
Conditions
Generalized Anxiety Disorder
Interventions
PF-06372865.
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 65 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
47
States / cities
Cerritos, California • Encino, California • Imperial, California + 41 more
Source: ClinicalTrials.gov public record
Updated Jan 8, 2017 · Synced Jun 10, 2026, 1:35 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Evaluating the Effects of Stress in Pregnancy

NCT00525226
View directory record Official record
Conditions
Depression, Panic Disorder, Generalized Anxiety Disorder, Post-Traumatic Stress Disorder, Obsessive Compulsive Disorder (OCD)
Interventions
Not listed
Lead sponsor
Emory University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
1,431 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 19, 2013 · Synced Jun 10, 2026, 1:35 PM EDT
Completed Not applicable Interventional

SkillJoy Clinical Trial

NCT05040061
View directory record Official record
Conditions
Generalized Anxiety Disorder
Interventions
SkillJoy Intervention, Active Self-Monitoring Control Intervention
Behavioral
Lead sponsor
Skidmore College
Other
Eligibility
18 Years and older
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Saratoga Springs, New York
Source: ClinicalTrials.gov public record
Updated Sep 9, 2021 · Synced Jun 10, 2026, 1:35 PM EDT
Completed Not applicable Interventional

Calmer Life: Testing the Effectiveness of a Treatment for Anxiety

NCT01702220
View directory record Official record
Conditions
Generalized Anxiety Disorder, Anxiety Disorder NOS
Interventions
CBT, ECC
Behavioral · Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
50 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 11, 2016 · Synced Jun 10, 2026, 1:35 PM EDT
Terminated Not applicable Interventional

Transcranial Pulse Near-Infrared Light in Generalized Anxiety Disorder: a Placebo-Controlled Study

NCT03420456
View directory record Official record
Conditions
Generalized Anxiety Disorder
Interventions
Transcranial Light Therapy
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 4, 2020 · Synced Jun 10, 2026, 1:35 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of ABBV-932 in Healthy Adult Participants, Participants With Generalized Anxiety Disorder (GAD) and Participants With Bipolar Disorder (BPD)

NCT06024239
View directory record Official record
Conditions
Healthy Volunteers, Generalized Anxiety Disorder (GAD), Bipolar Disorder (BPD)
Interventions
ABBV-932, Placebo for ABBV-932
Drug
Lead sponsor
AbbVie
Industry
Eligibility
18 Years to 65 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
3
States / cities
Los Alamitos, California • Grayslake, Illinois • Marlton, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 16, 2025 · Synced Jun 10, 2026, 1:35 PM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

ACT for Individuals With MNCD and Their Care Partners

NCT07239609
View directory record Official record
Conditions
Depression in Adults, Anxiety Disorder Generalized, Grief
Interventions
Acceptance Commitment Therapy
Behavioral
Lead sponsor
Texas Tech University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Jun 10, 2026, 1:35 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Intracranial Neurophysiological Signatures of Fear and Anxiety in Humans

NCT05120635
View directory record Official record
Conditions
Fear, GAD, Emotional Memory, PTSD
Interventions
Deep Brain Stimulation, Virtual and augmented reality tasks
Device · Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 70 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
2
States / cities
Los Angeles, California • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 15, 2025 · Synced Jun 10, 2026, 1:35 PM EDT
Withdrawn Not applicable Interventional

Worry Exposure for Generalized Anxiety Disorder

NCT02382224
View directory record Official record
Conditions
Generalized Anxiety Disorder
Interventions
Worry Exposure for GAD, 12-week Waitlist
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jul 23, 2018 · Synced Jun 10, 2026, 1:35 PM EDT
Completed Phase 4 Interventional Results available

Pharmacological Treatment of Generalized Anxiety Disorder in the Elderly

NCT00701675
View directory record Official record
Conditions
Generalized Anxiety Disorder
Interventions
sertraline 50 mg daily, sertraline 100 mg daily, Placebo 50 or 100 mg
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
60 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
3
States / cities
Tuscaloosa, Alabama • Miami, Florida • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Dec 28, 2016 · Synced Jun 10, 2026, 1:35 PM EDT
Completed Phase 3 Interventional Results available

Quetiapine Extended Release (XR) in Bipolar Patients With Comorbid Generalized Anxiety Disorder (GAD)

NCT00671853
View directory record Official record
Conditions
Bipolar Disorder, Anxiety, Anxiety Disorders, Substance Use Disorders
Interventions
Quetiapine XR, Placebo for quetiapine XR
Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 28, 2016 · Synced Jun 10, 2026, 1:35 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Switching From an SSRI to Tiagabine(GABITRIL) in Order to Alleviate SSRI Induced Sexual Dysfunction

NCT00174850
View directory record Official record
Conditions
Anxiety, Sexual Dysfunction
Interventions
Gaitril
Drug
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
18 Years to 64 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2005
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Sep 17, 2008 · Synced Jun 10, 2026, 1:35 PM EDT
Active, not recruiting Phase 4 Interventional Accepts healthy volunteers

Brain Stimulation & Generalized Anxiety Study

NCT04751864
View directory record Official record
Conditions
Anxiety, Generalized Anxiety Disorder, Generalized Anxiety
Interventions
Cranial Electrotherapy Stimulator (CES) Device
Device
Lead sponsor
ProofPilot
Industry
Eligibility
21 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 11, 2021 · Synced Jun 10, 2026, 1:35 PM EDT
Completed Phase 3 Interventional Results available

Safety, Efficacy and Tolerability of Vilazodone in Patients With Generalized Anxiety Disorder

NCT01766401
View directory record Official record
Conditions
Generalized Anxiety Disorder
Interventions
Placebo, Vilazadone
Drug
Lead sponsor
Forest Laboratories
Industry
Eligibility
18 Years to 70 Years
Enrollment
402 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
30
States / cities
Arcadia, California • Beverly Hills, California • Encino, California + 26 more
Source: ClinicalTrials.gov public record
Updated Dec 17, 2019 · Synced Jun 10, 2026, 1:35 PM EDT
Completed Not applicable Interventional

Efficacy of Adding Interpersonal and Emotional Processing Therapy Techniques to Cognitive Behavioral Therapy to Treat Generalized Anxiety Disorder

NCT00951652
View directory record Official record
Conditions
Generalized Anxiety Disorder
Interventions
CBT, Interpersonal and emotional processing therapy, supportive listening
Behavioral · Other
Lead sponsor
Michelle G. Newman
Other
Eligibility
18 Years to 65 Years
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2005
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 24, 2022 · Synced Jun 10, 2026, 1:35 PM EDT