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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Anxiety Fear Clear all
Completed Phase 1 Interventional

Intervention for Anxiety After Falls

NCT01268657
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD), Specific Phobia, Anxiety
Interventions
Education, Relaxation Training, Cognitive Restructuring, Behavioral Activation, Exposure
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
65 Years to 105 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 15, 2016 · Synced Sep 26, 2026, 2:27 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Neuroimaging Memories of Fear and Safety in the Human Brain

NCT04975009
View directory record Official record
Conditions
Fear Anxiety, PTSD
Interventions
Fear conditioning
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 50 Years
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
2
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated May 16, 2022 · Synced Sep 26, 2026, 2:27 AM EDT
Not listed Not applicable Interventional

Neuroimaging of Pavlovian Fear Conditioning Processes in Patients With Pathological Anxiety

NCT03498599
View directory record Official record
Conditions
Post Traumatic Stress Disorder, Anxiety Disorders, Panic Disorder, Social Phobia, Phobia
Interventions
Novelty facilitated extinction, Standard Extinction
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 50 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Apr 12, 2018 · Synced Sep 26, 2026, 2:27 AM EDT
Completed Not applicable Interventional

Trial of Written Exposure for Metastatic Cancer Patients (EASE)

NCT06042400
View directory record Official record
Conditions
Metastatic Cancer, Solid Tumor Cancer, Lymphoproliferative Disorders, Anxiety, Post-traumatic Stress Symptoms, Fear of Cancer Progression
Interventions
Written Exposure Therapy
Behavioral
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 4, 2023 · Synced Sep 26, 2026, 2:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Memory and Fear Study (Fear of Memory Loss Study)

NCT04821960
View directory record Official record
Conditions
Anxiety and Fear
Interventions
Tailored Mindfulness Program for Fear of Memory Loss, Conventional Mindfulness Program
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
55 Years and older
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 15, 2024 · Synced Sep 26, 2026, 2:27 AM EDT
Terminated Not applicable Interventional Results available

The Reducing Exercise Sensitivity With Exposure Training (RESET) Study

NCT05099926
View directory record Official record
Conditions
Acute Coronary Syndrome, Fear Anxiety, Physical Inactivity
Interventions
Reducing Exercise Sensitivity with Exposure Training
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 3, 2024 · Synced Sep 26, 2026, 2:27 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

K08 VR Fear Conditioning

NCT07216222
View directory record Official record
Conditions
Anxiety and Fear, PTSD, Veteran
Interventions
Deep Brain Stimulation
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 70 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 13, 2025 · Synced Sep 26, 2026, 2:27 AM EDT
Not listed Phase 1Phase 2 Interventional

Impact of CBD-Rich Oil on Aversive Memory Reconsolidation

NCT04726475
View directory record Official record
Conditions
Anxiety and Fear
Interventions
Interoceptive Aversive Memory Reactivation, Cannabidiol (CBD)-Rich Broad Spectrum Hemp Extract Oil, Placebo Oil
Behavioral · Dietary Supplement
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 65 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jan 18, 2022 · Synced Sep 26, 2026, 2:27 AM EDT
Recruiting Not applicable Interventional

Removing Surrogates Uncertainty to Reduce Fear and Anxiety After Cardiac Events - Kids

NCT07707037
View directory record Official record
Conditions
Cardiac Arrest, Anxiety Depression, Family Support
Interventions
Education Intervention
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
0 Days to 17 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Sep 26, 2026, 2:27 AM EDT
Active, not recruiting Not applicable Interventional

Pursuing Exploration Into the Supportive Care Needs and Intervention Preferences of Survivors of Testicular Cancer

NCT07228637
View directory record Official record
Conditions
Testicular Cancer
Interventions
Acceptance and Commitment Therapy (ACT) Coaching, Education and Support Coaching
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 40 Years · Male only
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 8, 2026 · Synced Sep 26, 2026, 2:27 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Transcranial Direct Current Stimulation and Extinction in Obsessive Compulsive Disorder

NCT06834217
View directory record Official record
Conditions
Obsessive Compulsive Disorder (OCD)
Interventions
Active transcranial direct current stimulation, Sham transcranial direct current stimulation
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years to 70 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Sep 26, 2026, 2:27 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Social Support and Reduced Fear Acquisition

NCT04564976
View directory record Official record
Conditions
Fear, Anxiety
Interventions
Social support image
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 55 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Sep 26, 2026, 2:27 AM EDT
Completed Not applicable Interventional Results available

Transcranial Direct Current Stimulation Potentiation of Fear Extinction in OCD

NCT05521074
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Active tDCS, Sham tDCS
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 60 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Sep 26, 2026, 2:27 AM EDT
Completed Not applicable Interventional

Facilitating Adaptive Coping With Fear of Recurrence Among Breast Cancer Survivors

NCT05364450
View directory record Official record
Conditions
Breast Neoplasm, Breast Cancer, Breast Carcinoma, Malignant Neoplasm of Breast, Cancer of Breast, Mammary Neoplasms, Human, Human Mammary Carcinoma, Malignant Tumor of Breast, Mammary Cancer, Mammary Carcinoma, Human, Anxiety, Fear
Interventions
Enhanced Usual Care, Acceptance Commitment Therapy, Cognitive Behavioral Therapy
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
390 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Dec 3, 2024 · Synced Sep 26, 2026, 2:27 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Thimble Mindfulness App and Recovery Patch Descriptions

NCT05980247
View directory record Official record
Conditions
Needle Fear, Vaccine Hesitancy
Interventions
Thimble Application
Device
Lead sponsor
Bianca Edison
Other
Eligibility
5 Years to 11 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 29, 2025 · Synced Sep 26, 2026, 2:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Arousal and Stress in Anxiety

NCT00026559
View directory record Official record
Conditions
Healthy Volunteers
Interventions
Shock Device, Auditory Startle Device
Device
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
18 Years to 50 Years
Enrollment
1,418 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2022
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 8, 2024 · Synced Sep 26, 2026, 2:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Remote Yoga Nidra for Anxiety and Sleep

NCT04571593
View directory record Official record
Conditions
Insomnia Due to Anxiety and Fear
Interventions
Yoga Nidra
Behavioral
Lead sponsor
National University of Natural Medicine
Other
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 17, 2023 · Synced Sep 26, 2026, 2:27 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

A Randomized Controlled Test of the Effects of CHI-554 on Fear.

NCT04577612
View directory record Official record
Conditions
Anxiety, Fear, Panic
Interventions
CHI-554
Drug
Lead sponsor
Canopy Growth Corporation
Industry
Eligibility
18 Years to 55 Years
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Fayetteville, Arkansas
Source: ClinicalTrials.gov public record
Updated Jun 2, 2021 · Synced Sep 26, 2026, 2:27 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Cognitive Behavioral Therapy (CBT) for Anxiety Disorders in Autism: Adapting Treatment for Adolescents

NCT01177969
View directory record Official record
Conditions
Anxiety Disorders in Youth With Autism, Asperger's Syndrome, and Pervasive Developmental Disorder Not Otherwise Specified
Interventions
Cognitive-Behavioral Therapy, Wait-list
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
11 Years to 14 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
2
States / cities
Los Angeles, California • St. Petersburg, Florida
Source: ClinicalTrials.gov public record
Updated Jun 30, 2014 · Synced Sep 26, 2026, 2:27 AM EDT
Completed Not applicable Interventional

Using Smartphones to Enhance the Treatment of Childhood Anxiety

NCT02259036
View directory record Official record
Conditions
Anxiety
Interventions
Ecological Momentary Treatment Enhancement
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
9 Years to 14 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 15, 2018 · Synced Sep 26, 2026, 2:27 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Exercise Facilitation of Adolescent Fear Extinction, Frontolimbic Circuitry, and Endocannabinoids

NCT06297278
View directory record Official record
Conditions
Adolescence
Interventions
Moderate Intensity Exercise
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
14 Years to 17 Years
Enrollment
174 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 6, 2025 · Synced Sep 26, 2026, 2:27 AM EDT
Completed Not applicable Interventional

Using Bilateral Stimulation (A Pre-existing Trauma Technique) After Eating to Reduce Anxiety in People Recovering From Eating Disorders

NCT07600970
View directory record Official record
Conditions
Eating Disorders, Eating Disorders Symptoms
Interventions
Bilateral Stimulation
Behavioral
Lead sponsor
San Francisco State University
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Sep 26, 2026, 2:27 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Effect of D-cycloserine on Extinction of Fear Conditioning

NCT00352586
View directory record Official record
Conditions
Fear
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
18 Years to 50 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2008
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Sep 26, 2026, 2:27 AM EDT
Recruiting Not applicable Interventional

Unconscious Reduction of Fear Through Decoded Neuro-Reinforcement

NCT06420557
View directory record Official record
Conditions
Phobia
Interventions
Unconscious Neuro-reinforcement
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 1, 2025 · Synced Sep 26, 2026, 2:27 AM EDT