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ClinicalTrials.gov public records Last synced Oct 21, 2026, 1:14 AM EDT

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Showing 1–24 of 53 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Anxiety Postoperative Clear all
Withdrawn Not applicable Interventional

Longitudinal Virtual Reality Use in Pediatric Surgical Procedures

NCT03832478
View directory record Official record
Conditions
Anxiety, Pain, Pain, Postoperative
Interventions
Virtual Reality Headset Given
Device
Lead sponsor
Stanford University
Other
Eligibility
5 Years to 25 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
2
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Mar 22, 2021 · Synced Oct 21, 2026, 1:14 AM EDT
Completed Not applicable Interventional

Pragmatic Research eXamining Inpatient Symptoms

NCT01988194
View directory record Official record
Conditions
Postoperative Pain, Nausea, Vomiting, Anxiety, Depression
Interventions
Acupuncture
Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
238 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 9, 2020 · Synced Oct 21, 2026, 1:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Utilization of Different Virtual Reality Experiences

NCT04828980
View directory record Official record
Conditions
Surgery, Pain, Postoperative, Anxiety, Otolaryngological Disease
Interventions
Oculus Quest: TRIPP, Oculus Quest: Angry Birds
Device
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 89 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 31, 2023 · Synced Oct 21, 2026, 1:14 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Meditation Effects on Discomfort, Pain InTerference, and AnxieTy After urEteroscopy

NCT06783946
View directory record Official record
Conditions
Kidney Stone, Pain, Postoperative, Anxiety Postoperative
Interventions
Meditation
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
12 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 4, 2025 · Synced Oct 21, 2026, 1:14 AM EDT
Recruiting Not applicable Interventional

Green Light for Post-Operative Wellness

NCT07218289
View directory record Official record
Conditions
Surgery
Interventions
Bright Green Light Therapy, Dim White Light Therapy
Device
Lead sponsor
Rebecca E Kotcher, MD
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Oct 21, 2026, 1:14 AM EDT
Withdrawn Not applicable Interventional

Effects of Massage on Post-operative Pain in Urologic Patients

NCT02209233
View directory record Official record
Conditions
Postoperative Pain, Anxiety
Interventions
Massage Therapy
Other
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2015
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Feb 9, 2015 · Synced Oct 21, 2026, 1:14 AM EDT
Terminated Phase 3 Interventional

Effect of Music on Pain and Anxiety After Surgery

NCT01409044
View directory record Official record
Conditions
Postop Adult ICU Patients
Interventions
Music
Other
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years to 99 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 10, 2017 · Synced Oct 21, 2026, 1:14 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Feasibility of Breathwork Intervention With Older Adults After Knee Surgery

NCT07464860
View directory record Official record
Conditions
Surgical Stress Response, Stress Physiological, Stress Physiology, Stress Psychological, Breathing Techniques, Breathing Exercises, Hypothalamic Pituitary Adrenal, Relaxation, Relaxation Therapy, Cortisol, Postoperative Pain, Postoperative Anxiety, Postoperative Depression, Quality of Recovery (QoR-15)
Interventions
A 5-minute Asynchronous Breathwork Intervention, A 5-minute Asynchronous Card Game Video
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
65 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Oct 21, 2026, 1:14 AM EDT
Withdrawn Phase 2 Interventional Accepts healthy volunteers

Exploring the Impact of Perioperative Galacto-Oligosaccharides (GOS) on Stress, Anxiety and Cognition

NCT02953691
View directory record Official record
Conditions
Anxiety, Pain, Surgery
Interventions
Galacto-Oligosaccharide, Maltodextrin (Placebo)
Drug
Lead sponsor
Jeff Taekman, M.D.
Other
Eligibility
21 Years to 70 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 31, 2018 · Synced Oct 21, 2026, 1:14 AM EDT
Completed Not applicable Interventional

Preventing Persistent Pain and Reducing Depressive and Anxious Symptoms Following Mastectomy and Lumpectomy

NCT03430765
View directory record Official record
Conditions
Persistent Postsurgical Pain, Breast Cancer Female, Ductal Carcinoma in Situ
Interventions
Acceptance and Commitment Therapy
Behavioral
Lead sponsor
Katherine Hadlandsmyth
Other
Eligibility
18 Years to 100 Years · Female only
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Feb 11, 2019 · Synced Oct 21, 2026, 1:14 AM EDT
Completed Not applicable Interventional

Virtual Reality and Pain

NCT04351776
View directory record Official record
Conditions
Pain, Postoperative, Pain, Anxiety Postoperative
Interventions
VR-Biofeedback, VR-Distraction, 360 Video
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
8 Years to 18 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 31, 2023 · Synced Oct 21, 2026, 1:14 AM EDT
Completed Not applicable Interventional

Live Music Therapy to Reduce Anxiety, Pain and Improve Sleep in Post-Operative Lung Transplant Patients: a Pilot Study

NCT04975607
View directory record Official record
Conditions
Lung Transplant; Complications
Interventions
Music Therapy
Behavioral
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
Not listed
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 10, 2025 · Synced Oct 21, 2026, 1:14 AM EDT
Recruiting Not applicable Interventional

Using Mindfulness in an Enhanced Recovery After Surgery Protocol to Support Recovery After Colorectal Surgery

NCT07026786
View directory record Official record
Conditions
Pain After Surgery, Anxiety After Surgery
Interventions
Mindfulness Intervention
Behavioral
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 21, 2026, 1:14 AM EDT
Completed Not applicable Interventional Results available

The Effect of Jazz on Postoperative Pain and Stress in Patients Undergoing Elective Hysterectomy

NCT01834027
View directory record Official record
Conditions
Pain, Anxiety
Interventions
Jazz music, No music
Behavioral
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 15, 2016 · Synced Oct 21, 2026, 1:14 AM EDT
Completed Not applicable Interventional

Aromatherapy in Total Knee Replacement

NCT06045078
View directory record Official record
Conditions
Total Knee Replacement, Post-operative Nausea and Vomiting, Opioid Use, Anxiety, Depression, Post Operative Pain
Interventions
Elequil Lavender-peppermint Aromatabs, Elequil Almond-Oil Aromatabs
Other
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 27, 2025 · Synced Oct 21, 2026, 1:14 AM EDT
Recruiting Not applicable Interventional

RXWell to Decrease Post-Operative Opioid Use in Total Knee or Hip Arthroplasty

NCT05658796
View directory record Official record
Conditions
Mood Disorders, Anxiety, Depressive Symptoms, Depression, Anxiety Disorders, Anxiety Depression
Interventions
-RxWell
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 100 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
3
States / cities
Monroeville, Pennsylvania • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Oct 21, 2026, 1:14 AM EDT
Recruiting Not applicable Interventional

Randomized Controlled Trial of the STEIN Protocol: A Neuroplastic Pain Education and Guided Breathing Intervention During Awake Cataract Surgery

NCT07715591
View directory record Official record
Conditions
Cataract, Cataract (Post-operative Cataract Surgery Follow-up)
Interventions
Music and Guided Imagery, Control, Music Only
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
Not listed
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 21, 2026, 1:14 AM EDT
Completed Not applicable Interventional Results available

A Single Blinded Randomized Controlled Trial Testing the Efficacy of a Pediatric Interactive Relational Agent vs. Standard Preoperative Education

NCT04586569
View directory record Official record
Conditions
Anesthesia, Anesthesia Emergence Delirium, Procedural Anxiety
Interventions
Pediatric Interactive Relational Agent (PIRA)
Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
4 Years to 10 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Waltham, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 4, 2025 · Synced Oct 21, 2026, 1:14 AM EDT
Recruiting Not applicable Interventional

Weighted Blankets for Postsurgical Pain

NCT05324254
View directory record Official record
Conditions
Pain, Postsurgical
Interventions
Weighted blanket
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
168 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Oct 21, 2026, 1:14 AM EDT
Recruiting Not applicable Interventional

Virtual Reality as a Method for Pain and Anxiety Control During First Trimester Procedural Abortion

NCT07288047
View directory record Official record
Conditions
Abortion, First Trimester, Pain Management, Pain After Surgery, Satisfaction, Satisfaction With Care, Anxiety After Surgery
Interventions
VR headset, Usual Care
Device · Other
Lead sponsor
Study Investigator
Other
Eligibility
18 Years and older · Female only
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 21, 2026, 1:14 AM EDT
Not yet recruiting Not applicable Interventional

Brief Postoperative Pain Management Intervention: Meaning Making Amendment

NCT07676500
View directory record Official record
Conditions
Pain, Acute, Anxiety Acute
Interventions
Mindfulness + Meaning Making Questions, Mindfulness + Implementation Questions
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
576 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Oct 21, 2026, 1:14 AM EDT
Withdrawn No phase listed Observational

Factors Affecting Perioperative Outcomes

NCT01530191
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Not listed
Lead sponsor
University of Oklahoma
Other
Eligibility
21 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Oct 16, 2013 · Synced Oct 21, 2026, 1:14 AM EDT
Completed Phase 4 Interventional Results available

Preventing Post-Operative Delirium in Patients Undergoing a Pneumonectomy, Esophagectomy or Thoracotomy

NCT02213900
View directory record Official record
Conditions
Delirium, Cognitive Impairment, Post-traumatic Stress Disorder, Depression, Anxiety
Interventions
Haloperidol, Placebo
Drug
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 13, 2017 · Synced Oct 21, 2026, 1:14 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Educational Brochure in Preparing Patients With Gastric Cancer and Their Caregivers for Recovery After Surgery

NCT02334332
View directory record Official record
Conditions
Anxiety, Gastric Carcinoma, Stress
Interventions
Educational Intervention, Standard Follow-Up Care, Quality-of-Life Assessment
Other · Procedure
Lead sponsor
City of Hope Medical Center
Other
Eligibility
21 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
Duarte, California
Source: ClinicalTrials.gov public record
Updated Sep 25, 2015 · Synced Oct 21, 2026, 1:14 AM EDT