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Showing 1–24 of 46 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Anxiety Preoperative Clear all
Completed Not applicable Interventional

Does Distraction With a Hand Held Video Game Reduce Preoperative and Emergence Anxiety in Children?

NCT00932685
View directory record Official record
Conditions
Pediatric Emergence Agitation and Pain
Interventions
Midazolam, Game Boy
Drug · Device
Lead sponsor
University of Medicine and Dentistry of New Jersey
Other
Eligibility
4 Years to 12 Years
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 2, 2009 · Synced Jul 23, 2026, 11:49 PM EDT
Completed Phase 2 Interventional

A GameBoy as a Distraction Before Surgery in Children

NCT00176670
View directory record Official record
Conditions
Anxiety
Interventions
midazolam or GameBoy or parental presence
Drug
Lead sponsor
University of Medicine and Dentistry of New Jersey
Other
Eligibility
4 Years to 16 Years
Enrollment
158 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 5, 2016 · Synced Jul 23, 2026, 11:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparing Virtual Reality (VR) to Non-VR for Decreasing Preoperative/Procedural Anxiety

NCT05094141
View directory record Official record
Conditions
Preoperative Anxiety
Interventions
Virtual reality
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
5 Years to 12 Years
Enrollment
89 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 10, 2025 · Synced Jul 23, 2026, 11:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of High-quality Pre-operative Videos on Patient Anxiety Levels Prior to Ambulatory Hand Surgery

NCT04424810
View directory record Official record
Conditions
Anxiety, Carpal Tunnel Syndrome, Trigger Finger, Engagement, Patient, Pain
Interventions
High-quality, physician created video, Standard of care
Other
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
167 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Sep 4, 2021 · Synced Jul 23, 2026, 11:49 PM EDT
Completed Not applicable Interventional Results available

Preoperative Acupuncture for Total Knee or Hip Arthroplasty

NCT06099223
View directory record Official record
Conditions
Knee Arthropathy, Hip Arthropathy, Anxiety
Interventions
Acupuncture needles
Device
Lead sponsor
Hartford Hospital
Other
Eligibility
18 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 25, 2025 · Synced Jul 23, 2026, 11:49 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Preoperative Hip Knee Anxiety Sleep Study

NCT04180527
View directory record Official record
Conditions
Anxiety, Sleep, Surgery
Interventions
Not listed
Lead sponsor
Henry Ford Health System
Other
Eligibility
Not listed
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 14, 2022 · Synced Jul 23, 2026, 11:49 PM EDT
Completed Not applicable Interventional

The Effect of Mirror Education for Women Undergoing Mastectomy

NCT01642628
View directory record Official record
Conditions
Emotional Distress, Anxiety, Depression
Interventions
Mirror Education
Other
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years and older · Female only
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 31, 2014 · Synced Jul 23, 2026, 11:49 PM EDT
Recruiting Not applicable Interventional

WashU DIEP Flap Video and Patient Understanding Improvement

NCT06864754
View directory record Official record
Conditions
Breast Cancer
Interventions
WashU DIEP Flap Video
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older · Female only
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 23, 2025 · Synced Jul 23, 2026, 11:49 PM EDT
Completed Phase 3 Interventional Results available

Music vs Midazolam During Preop Nerve Block Placement

NCT03069677
View directory record Official record
Conditions
Anxiety, Peripheral Nerve Block
Interventions
music, Midazolam
Other · Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 9, 2019 · Synced Jul 23, 2026, 11:49 PM EDT
Completed Not applicable Interventional Results available

Randomized, Placebo-Controlled Study: Effects of Lavender Aromatherapy on Preoperative Anxiety in Breast Patients

NCT01837966
View directory record Official record
Conditions
Anxiety; Generalized, Breast Diseases, Surgery
Interventions
Lavender oil, Placebo
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older · Female only
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 2, 2017 · Synced Jul 23, 2026, 11:49 PM EDT
Completed No phase listed Observational

Preoperative Anxiety Evaluation: a New Visual Smileys Scale

NCT02667847
View directory record Official record
Conditions
Anxiety, Preoperative
Interventions
Not listed
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 2, 2016 · Synced Jul 23, 2026, 11:49 PM EDT
Enrolling by invitation Not applicable Interventional

Impact of Immersive Video Education on Cardiothoracic Surgery Anxiety and Outcomes

NCT07222839
View directory record Official record
Conditions
Anxiety
Interventions
Visually Immersive Video, Standard of Care
Behavioral
Lead sponsor
Baptist Health South Florida
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Jul 23, 2026, 11:49 PM EDT
Completed Phase 1 Interventional

Massage Therapy and Port-a-Catheter Insertion

NCT00991770
View directory record Official record
Conditions
Cancer, Anxiety, Pain, Surgery
Interventions
Massage Therapy, Attention Control
Other
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 6, 2011 · Synced Jul 23, 2026, 11:49 PM EDT
Completed Not applicable Interventional

Animated Video Consultation for Reducing Pre-Operative Anxiety in Outpatient Dermatologic Surgery

NCT03344497
View directory record Official record
Conditions
Dermatology/Skin - Other
Interventions
VC Group
Other
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jun 24, 2019 · Synced Jul 23, 2026, 11:49 PM EDT
Active, not recruiting Not applicable Interventional

Impact of Preop Video on Patient Anxiety

NCT05633901
View directory record Official record
Conditions
Prolapse, Vaginal, Prolapse, Uterine, Prolapse; Female
Interventions
Educational Video, Standard Counseling
Other
Lead sponsor
TriHealth Inc.
Other
Eligibility
18 Years and older · Female only
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
2
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 21, 2024 · Synced Jul 23, 2026, 11:49 PM EDT
Completed Not applicable Interventional

Preoperative Guided Imagery in Patients Undergoing Urologic Surgery

NCT05072639
View directory record Official record
Conditions
Urologic Cancer
Interventions
Guided Meditation
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
123 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 21, 2021 · Synced Jul 23, 2026, 11:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Preparing Children for Anesthesia With an Educational Pop-Up Book

NCT04796077
View directory record Official record
Conditions
Pediatric Preoperative Anxiety, Pediatric Coping
Interventions
Pop-Up Book
Other
Lead sponsor
Children's Healthcare of Atlanta
Other
Eligibility
5 Years to 12 Years
Enrollment
148 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Duluth, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 11, 2021 · Synced Jul 23, 2026, 11:49 PM EDT
Completed Not applicable Interventional

Use of Handheld Audiovisual Devices to Treat Pediatric Preoperative Anxiety

NCT02286674
View directory record Official record
Conditions
Pediatric Preoperative Anxiety
Interventions
Tablet (Audio/Visual Device)
Other
Lead sponsor
McLaren Health Care
Other
Eligibility
2 Years to 12 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 24, 2022 · Synced Jul 23, 2026, 11:49 PM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

Virtual Reality to Reduce Pre-Operative Anxiety

NCT04268914
View directory record Official record
Conditions
Virtual Reality, Augmented Reality, IV Stick, Mask Induction, Ambulatory Surgery, Pain, Anxiety
Interventions
Oculus Go VR, Mira Prism VR
Device
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
10 Years to 21 Years
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 26, 2023 · Synced Jul 23, 2026, 11:49 PM EDT
Terminated Phase 1Phase 2 Interventional Results available

Music vs Midazolam During Preop Nerve Block Placement - Part 2 Study On Anxiolytic Options Before Peripheral Nerve Blocks

NCT05610969
View directory record Official record
Conditions
Peripheral Nerve Block, Anxiety, Preoperative Anxiety
Interventions
Music, Midazolam
Other · Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 13, 2025 · Synced Jul 23, 2026, 11:49 PM EDT
Terminated No phase listed Observational Results available

Severity Postoperative Pain Prediction

NCT00638404
View directory record Official record
Conditions
Anxiety, Pain, Postoperative Pain
Interventions
Not listed
Lead sponsor
Wake Forest University
Other
Eligibility
18 Years and older · Female only
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 5, 2018 · Synced Jul 23, 2026, 11:49 PM EDT
Recruiting Not applicable Interventional

Pre-Operative Guided Meditation to Reduce Pre-Operative Anxiety in Patients Undergoing Cancer-Directed Surgery

NCT06949943
View directory record Official record
Conditions
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
Interventions
Behavioral Intervention, Electronic Health Record Review, Survey Administration
Behavioral · Other
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Jul 23, 2026, 11:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Preoperative Preparation for Children

NCT00205244
View directory record Official record
Conditions
Elective Surgery, Anxiety
Interventions
Healing images, relaxation and distraction materials
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
4 Years to 12 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Mar 11, 2019 · Synced Jul 23, 2026, 11:49 PM EDT
Completed Not applicable Interventional

Music Listening on Preoperative Anxiety in Female Pelvic Medicine and Reconstructive Surgery

NCT03651310
View directory record Official record
Conditions
Preoperative Anxiety
Interventions
Music Listening Group
Other
Lead sponsor
Loyola University
Other
Eligibility
18 Years and older · Female only
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Maywood, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 4, 2019 · Synced Jul 23, 2026, 11:49 PM EDT