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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Anxiety Sensitivity Clear all
Completed Not applicable Interventional

Amplification of Positivity to Enhance Social Connections in Anxiety and Depression

NCT04945239
View directory record Official record
Conditions
Depression, Anxiety Disorders and Symptoms
Interventions
Amplification of Positivity Training (6 Sessions), Stress Management Training (6 Sessions)
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 55 Years
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jan 7, 2025 · Synced Sep 23, 2026, 8:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Anxiety, Mood, and Health Behaviors in Young Adults

NCT03128437
View directory record Official record
Conditions
Anxiety Sensitivity
Interventions
Aerobic Exercise
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 35 Years
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Nov 24, 2019 · Synced Sep 23, 2026, 8:55 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Effects of Low-Level Laser Stimulation With and Without Fear Extinction Training

NCT02926352
View directory record Official record
Conditions
Phobias, Claustrophobia, Social Phobia
Interventions
Extinction Training, Low-Level Laser Therapy, Sham Low-Level Laser Therapy
Behavioral · Device
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 65 Years
Enrollment
112 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2020
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Dec 27, 2022 · Synced Sep 23, 2026, 8:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Smoking, Stress, HIV and Mobile Technology

NCT05709002
View directory record Official record
Conditions
Cigarette Smoking
Interventions
MASP+, Control
Behavioral
Lead sponsor
University of Houston
Other
Eligibility
18 Years and older
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Sep 23, 2026, 8:55 PM EDT
Recruiting Phase 2 Interventional

Enhancing Smoking Cessation for African American People Everywhere

NCT07024992
View directory record Official record
Conditions
ESCAPE Intervention+NRT, quitSTART Intervention+NRT, CTRL+NRT
Interventions
ESCAPE app + NRT, quiSTART app + NRT, Control (CTRL)
Behavioral
Lead sponsor
University of Houston
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Sep 23, 2026, 8:55 PM EDT
Completed Not applicable Interventional

Evaluation of the Texas Wellness Incentives and Navigation (WIN) Project

NCT02440906
View directory record Official record
Conditions
Chronic Mental Illness, Chronic Physical Illness
Interventions
Patient-Directed Wellness Account, Health Navigator
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 55 Years
Enrollment
1,663 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 2, 2017 · Synced Sep 23, 2026, 8:55 PM EDT
Completed Not applicable Interventional

Using Neurostimulation to Accelerate Change in Misophonia: a Pilot Study

NCT06333925
View directory record Official record
Conditions
Misophonia, Emotion Dysregulation, Sensory Processing Disorder, Auditory Over Responsivity, Anxiety Disorder, Sound Sensitivity
Interventions
High Frequency Repetitive Transcranial Magnetic Stimulation (HF rTMS), Sham Repetitive Transcranial Magnetic Stimulation (sham- rTMS), Cognitive Restructuring
Device · Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 55 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Sep 23, 2026, 8:55 PM EDT
Completed Not applicable Interventional

Effectiveness of an Integrated Treatment to Address Smoking Cessation and Anxiety/ Depression in People Living With HIV

NCT03904186
View directory record Official record
Conditions
Human Immunodeficiency Virus, Smoking Cessation, Smoking, Cigarette, Smoking, Anxiety, Depression, Nicotine Dependence
Interventions
QUIT, Time-Matched Control (TM)
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 79 Years
Enrollment
131 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
3
States / cities
Boston, Massachusetts • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 8, 2026 · Synced Sep 23, 2026, 8:55 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Disentangling Anxiety Sensitivity and Anxiety-induced Physiological Stress Response

NCT02372110
View directory record Official record
Conditions
Anxiety
Interventions
HPA, ANS stimulation, Placebo
Drug
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Apr 27, 2021 · Synced Sep 23, 2026, 8:55 PM EDT
Recruiting Not applicable Interventional

Reaching Calm: A Digital Intervention to Prevent Perinatal Anxiety Disorders

NCT07458698
View directory record Official record
Conditions
Perinatal Anxiety, Anxiety Sensitivity, Perinatal Depression
Interventions
Digital mental health intervention
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Leominster, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Sep 23, 2026, 8:55 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions

NCT01931644
View directory record Official record
Conditions
All Diagnosed Health Conditions, ADD/ADHD, Alopecia Areata, Ankylosing Spondylitis, Asthma, Atopic Dermatitis Eczema, Beta Thalassemia, Bipolar Disorder, Breast Cancer, Celiac Disease, Cervical Cancer, Chronic Inflammatory Demyelinating Polyneuropathy, Chronic Kidney Diseases, Chronic Obstructive Pulmonary Disease, Colon Cancer, Colorectal Cancer, Crohn's Disease, Cystic Fibrosis, Depression, Diabetes Mellitus, Duchenne Muscular Dystrophy, Endometriosis, Epilepsy, Facioscapulohumeral Muscular Dystrophy, G6PD Deficiency, General Anxiety Disorder, Hepatitis B, Hereditary Hemorrhagic Telangiectasia, HIV/AIDS, Human Papilloma Virus, Huntington's Disease, Idiopathic Thrombocytopenic Purpura, Insomnia, Kidney Cancer, Leukemia, Lung Cancer, Lupus Nephritis, Lymphoma, Melanoma, Multiple Myeloma, Multiple Sclerosis, Myositis, Myotonic Dystrophy, Ovarian Cancer, Pancreatic Cancer, Parkinson's Disease, Polycystic Kidney Diseases, Prostate Cancer, Psoriasis, Psoriatic Arthritis, Rosacea, Scleroderma, Sickle Cell Anemia, Sickle Cell Trait, Sjogren's Syndrome, Skin Cancer, Spinal Muscular Atrophy, Systemic Lupus Erythematosus, Thrombotic Thrombocytopenic Purpura, Trisomy 21, Ulcerative Colitis
Interventions
Not listed
Lead sponsor
Sanguine Biosciences
Industry
Eligibility
18 Years to 100 Years
Enrollment
17,667 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 17, 2024 · Synced Sep 23, 2026, 8:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Predicting Treatment Response to Exposure Therapy Using Carbon Dioxide

NCT03925987
View directory record Official record
Conditions
Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder, Agoraphobia
Interventions
Exposure therapy
Behavioral
Lead sponsor
Laureate Institute for Brain Research, Inc.
Other
Eligibility
18 Years to 55 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Dec 14, 2023 · Synced Sep 23, 2026, 8:55 PM EDT
Completed Not applicable Interventional

Anxiety Sensitivity Treatment for Heroin Users

NCT01196312
View directory record Official record
Conditions
Anxiety
Interventions
Anxiety sensitivity therapy
Behavioral
Lead sponsor
University of Maryland, College Park
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated May 29, 2023 · Synced Sep 23, 2026, 8:55 PM EDT
Recruiting Phase 3 Interventional Accepts healthy volunteers

Community-based Smoking Cessation Treatment for Adults With High Stress Sensitivity.

NCT06053567
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Aerobic Exercise, Counseling, Nicotine patch
Behavioral · Drug
Lead sponsor
Jasper A. Smits
Other
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2029
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Sep 23, 2026, 8:55 PM EDT
Completed Not applicable Interventional

Affect Treatment for Depression and Anxiety

NCT05203861
View directory record Official record
Conditions
Depression, Anxiety
Interventions
Positive Affect Treatment, Negative Affect Treatment
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
2
States / cities
Los Angeles, California • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Apr 24, 2025 · Synced Sep 23, 2026, 8:55 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Do Bonding Disruptions Occur More Often in Children With Asthma Than in Non-asthmatic Populations?

NCT02158338
View directory record Official record
Conditions
Asthma in Children, Anxiety
Interventions
Asthma, Non-asthma
Other
Lead sponsor
Ran Anbar
Other
Eligibility
Female only
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Jun 1, 2015 · Synced Sep 23, 2026, 8:55 PM EDT
Completed Not applicable Interventional Results available

Reward Processes and Rehearsal in Exposure Therapy

NCT06132425
View directory record Official record
Conditions
Anxiety Disorders, Public Speaking Fear
Interventions
Exposure, Rehearsal
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 12, 2025 · Synced Sep 23, 2026, 8:55 PM EDT
Active, not recruiting Phase 2 Interventional

Pramipexole to Enhance Social Connections

NCT06269146
View directory record Official record
Conditions
Anxiety Disorders, Anxiety, Depression, Social Disconnection
Interventions
Pramipexole Pill, Placebo Pill
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 50 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
San Diego, California • New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 22, 2026 · Synced Sep 23, 2026, 8:55 PM EDT
Completed Phase 2 Interventional

Development of an Anxiety Sensitivity-Based Intervention for Substance Use and Anxiety Comorbidity

NCT02667015
View directory record Official record
Conditions
Other (or Unknown) Substance Use Disorders
Interventions
Psychotherapy (Anxiety Sensitivity Intervention)
Behavioral
Lead sponsor
Hartford Hospital
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 27, 2016 · Synced Sep 23, 2026, 8:55 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

VR to Reduce Pain/Anxiety During Painful Procedures

NCT04268901
View directory record Official record
Conditions
Phlebotomy, Orthopedics, Radiology, Pain, Anxiety, Virtual Reality, Allergy, Gastroenterology
Interventions
Samsung Gear VR, Merge VR, Oculus Go
Device
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
7 Years to 21 Years
Enrollment
700 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2025
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 26, 2023 · Synced Sep 23, 2026, 8:55 PM EDT
Recruiting Not applicable Interventional

Virtual Patient Groups for Sarcoidosis Associated Fatigue

NCT07073963
View directory record Official record
Conditions
Sarcoidosis, Fatigue, Depression, Anxiety, Mental Health
Interventions
Virtual Mindfulness Based Stress Reduction Group, Virtual sarcoidosis support group
Behavioral
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Sep 23, 2026, 8:55 PM EDT
Recruiting Not applicable Interventional

Interoceptive Training Enhanced Mindfulness

NCT06786572
View directory record Official record
Conditions
Anxiety Sensitivity
Interventions
Mindfulness training, Interoceptive exposure
Other · Behavioral
Lead sponsor
Veterans Medical Research Foundation
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 1, 2026 · Synced Sep 23, 2026, 8:55 PM EDT
Completed Not applicable Interventional

Anxiety Sensitivity Program for Smoking Cessation

NCT00387049
View directory record Official record
Conditions
Smoking Cessation
Interventions
Anxiety Sensitivity Program for Smoking Cessation
Behavioral
Lead sponsor
University of Vermont
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Oct 21, 2010 · Synced Sep 23, 2026, 8:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Testing of a Mobile Web App to Decrease Posttraumatic Stress Symptoms in Women After Sexual Assault

NCT04334356
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Mobile Web App
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
2
States / cities
Colorado Springs, Colorado • Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 20, 2023 · Synced Sep 23, 2026, 8:55 PM EDT