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Showing 1–24 of 52 matching trials from the live ClinicalTrials.gov search.
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Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Transcutaneous Vagus Nerve Stimulation (tVNS) and Stress Regulation During Performance Tasks

NCT07470229
Conditions
Stress Response
Interventions
Transcutaneous Vagus Nerve Stimulation (tVNS), Evaluative Stress Task
Device · Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Gainesville, Florida
Conditions
Mental Health Issue, Mental Health Disorder, Mental Health, Depression, Depression, Anxiety, Anxiety, Anxiety Disorders, Anxiety Depression, Anxiety State
Interventions
VIOME Precision Nutrition Program, Control arm
Combination Product · Other
Lead sponsor
Viome
Industry
Eligibility
25 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Bothell, Washington
Conditions
PTSD - Post Traumatic Stress Disorder
Interventions
Senseye Diagnostic Tool (DT), Clinician Administered PTSD Scale for DSM-5, Revised Version
Device · Behavioral
Lead sponsor
Senseye, Inc.
Industry
Eligibility
18 Years and older
Enrollment
1,900 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
5
States / cities
Aurora, Colorado • Savannah, Georgia • Meridian, Idaho + 2 more
Conditions
Anxiety State, Fascia; Anomaly
Interventions
Osteopathic Structural Exam, State - Trait Anxiety Questionnaire
Other
Lead sponsor
The Touro College and University System
Other
Eligibility
18 Years to 45 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
New York, New York
Conditions
Pain, Anxiety State, Depressive State
Interventions
Breath Counting, Body Scan, Mindful Breathing, Mindfulness of Pain, Mindful Savoring
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
823 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Salt Lake City, Utah
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cranial Electrotherapy Stimulation and Acute Stress

NCT06034496
Conditions
Anxiety State
Interventions
Active CES, Sham CES
Device
Lead sponsor
Tufts University
Other
Eligibility
18 Years to 40 Years
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Medford, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Music Listening on Nursing Students

NCT06647420
Conditions
Stress, Physiological Stress
Interventions
Sedative Music, Stimulative Music
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
3
States / cities
Coral Gables, Florida
Terminated Not applicable Interventional Accepts healthy volunteers

Effect of Metabolic State on Anxiety in Human Subjects

NCT01322243
Conditions
Healthy Volunteers
Interventions
Dietary manipulation
Other
Lead sponsor
Rockefeller University
Other
Eligibility
20 Years to 40 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
New York, New York
Conditions
Depressive Symptoms, Anxiety States, Neurotic
Interventions
Continuous Client Feedback, Continuous Self Feedback
Behavioral
Lead sponsor
Christiana Care Health Services
Other
Eligibility
18 Years to 64 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Wilmington, Delaware
Conditions
PreDiabetes, Heart Rate Variability (HRV), Stress and Anxiety, Stress Biomarkers
Interventions
Nature-based Walking, Built-environment/Commercial Walking
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
25 Years to 64 Years
Enrollment
216 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
3
States / cities
Lake Forest, Illinois • Winfield, Illinois • Minneapolis, Minnesota
Completed Not applicable Interventional Accepts healthy volunteers

Hypnosis-Based Machine Learning Biomarker Study

NCT07102810
Conditions
Disorder; Trance, Anxiety
Interventions
Standardized Hypnotic Susceptibility Testing
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
New York, New York
Completed No phase listed Observational Accepts healthy volunteers

The Effect of State and Trait Anxiety on Pain-pressure Threshold

NCT06047704
Conditions
Pain, Anxiety, Musculoskeletal Pain, Sensitisation
Interventions
No intervention
Other
Lead sponsor
Philadelphia College of Osteopathic Medicine
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Suwanee, Georgia
Conditions
Anxiety State
Interventions
Augmented Reality, Standard of Care preoperative teaching and handouts
Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Miami, Florida
Completed Not applicable Interventional Accepts healthy volunteers

The Effectiveness of Guided Imagery for a Nonprofit's Employees

NCT02191345
Conditions
Focus of Study, Stress
Interventions
Guided Imagery
Behavioral
Lead sponsor
FrontLine Service
Other
Eligibility
18 Years and older
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Anxiety, Cancer
Interventions
Music
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older · Female only
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Gainesville, Florida
Conditions
Anxiety Symptoms, Perceived Stress, Depressive Symptoms
Interventions
Lactobacillus reuteri DSM 17938, Placebo
Dietary Supplement · Other
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
18 Years to 45 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Boulder, Colorado
Completed Not applicable Interventional Accepts healthy volunteers

Treatment of Parental Anxiety Virtual Reality (VR)

NCT05729347
Conditions
Anxiety, Parents, Virtual Reality, State Anxiety, Trait Anxiety
Interventions
Virtual Reality headset with calming scenery
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 99 Years
Enrollment
485 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Stanford, California
Conditions
Obsessive-Compulsive Disorder
Interventions
Exposure and Response Prevention Therapy, Clinical Assessments, Research MRI Sessions
Behavioral · Other · Diagnostic Test
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
10 Years to 17 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
New York, New York
Conditions
Major Depressive Disorder, MDD, Generalized Anxiety Disorder, GAD, Depression, Anxiety
Interventions
Ampa One TMS System
Device
Lead sponsor
Biomedical Discoveries and Neuroscientific Foundations LLC
Industry
Eligibility
12 Years and older
Enrollment
5,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
2
States / cities
Encinitas, California • Plano, Texas
Conditions
Depression, Anxiety, Addiction, Emotion, Craving, Stress
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
18 Years to 55 Years
Enrollment
420 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
1
States / cities
Bethesda, Maryland
Completed Not applicable Interventional Accepts healthy volunteers

Health Benefits of Gardening

NCT03266120
Conditions
Anxiety, Depression, Healthy, Mood Disturbance, Stress, Quality of Life, Physical Activity, Social Interaction
Interventions
Art, Gardening
Other
Lead sponsor
University of Florida
Other
Eligibility
26 Years to 49 Years · Female only
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
2
States / cities
Gainesville, Florida
Completed Phase 3 Interventional Results available

Generalized Anxiety Disorder Adjunct Study

NCT00534599
Conditions
Anxiety, Anxiety Disorders, Anxiety Neuroses, Anxiety States
Interventions
Placebo, quetiapine fumarate XR
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years to 65 Years
Enrollment
409 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
53
States / cities
Birmingham, Alabama • Little Rock, Arkansas • Beverly Hills, California + 50 more
Conditions
Alcohol Use Disorder, Anxiety Disorder/Anxiety State, Stress Disorder, Hypothalamic Pituitary Adrenal, Drinking to Cope
Interventions
Not listed
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Minneapolis, Minnesota
Not listed Not applicable Interventional Accepts healthy volunteers

Mindful Waiting Room

NCT05433636
Conditions
Anxiety State, Depressive State, Pain, Nausea, Fatigue, Cancer
Interventions
Body Scan, Mindful Breathing, Mindfulness of Discomfort, Mindful Savoring, Integrative Health Recording
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
305 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Salt Lake City, Utah