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ClinicalTrials.gov public records Last synced Oct 9, 2026, 9:26 PM EDT

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Showing 121–144 of 277 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Aortic Aneurysm Clear all
Not listed Phase 3 Interventional

The Use of Nesiritide in Thoracic Aneurysm Repair to Prevent Acute Renal Failure

NCT00110201
View directory record Official record
Conditions
Cardiovascular Disease, Acute Renal Failure, Death
Interventions
Nesiritide
Drug
Lead sponsor
Ejaz, Abulate A, MD
Individual
Eligibility
18 Years and older
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 24, 2005 · Synced Oct 9, 2026, 9:26 PM EDT
Terminated Not applicable Interventional Results available

Visceral Manifold Study for the Repair of Thoracoabdominal Aortic Aneurysms

NCT03113383
View directory record Official record
Conditions
Thoracoabdominal Aortic Aneurysm
Interventions
Thoracoabdominal Aortic Aneurysm Repair
Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 8, 2022 · Synced Oct 9, 2026, 9:26 PM EDT
Recruiting Not applicable Interventional

A Study to Evaluate the Safety and Effectiveness of the Rapidlink Device When Used in Patients Undergoing an Open Surgical Procedure to Repair the Aorta

NCT07078383
View directory record Official record
Conditions
Aortic Aneurysm, Aortic Aneurysm and Dissection, Aortic Diseases, Aneurysm of Aorta, Thoracic, Aneurysmal Disease, Aorta, Thoracic Pathologies
Interventions
Rapidlink
Device
Lead sponsor
Vascutek Ltd.
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
15
States / cities
Los Angeles, California • Aurora, Colorado • Washington D.C., District of Columbia + 11 more
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Oct 9, 2026, 9:26 PM EDT
Completed No phase listed Observational

National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions

NCT01322165
View directory record Official record
Conditions
Marfan Syndrome, Turner Syndrome, Ehlers-Danlos Syndrome, Loeys-Dietz Syndrome, FBN1, TGFBR1, TGFBR2, ACTA2 or MYH11 Genetic Mutation, Bicuspid Aortic Valve Without Known Family History, Bicuspid Aortic Valve With Family History, Bicuspid Aortic Valve With Coarctation, Familial Thoracic Aortic Aneurysm and Dissections, Shprintzen-Goldberg Syndrome, Other Aneur/Diss of Thoracic Aorta Not Due to Trauma, <50yo, Other Congenital Heart Disease
Interventions
Not listed
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
Not listed
Enrollment
3,706 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2016
U.S. locations
7
States / cities
Honolulu, Hawaii • Baltimore, Maryland • New York, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Dec 20, 2016 · Synced Oct 9, 2026, 9:26 PM EDT
Completed Not applicable Interventional Results available

Suprarenal Proximal Cuff Study for Treatment of Abdominal Aortic Aneurysm

NCT00739401
View directory record Official record
Conditions
Abdominal Aortic Aneurysm
Interventions
Suprarenal Proximal Cuff Extension
Device
Lead sponsor
Endologix
Industry
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
8
States / cities
Miami Beach, Florida • Ocala, Florida • Orlando, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Dec 10, 2021 · Synced Oct 9, 2026, 9:26 PM EDT
Recruiting Not applicable Interventional

Treatment in Thoracic Aortic Aneurysm: Surgery vs Surveillance

NCT03536312
View directory record Official record
Conditions
Ascending Aortic Aneurysm Enlargement, Ascending Aorta Aneurysm
Interventions
Thoracic Aortic Surgery
Procedure
Lead sponsor
Ottawa Heart Institute Research Corporation
Other
Eligibility
18 Years to 79 Years
Enrollment
610 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2035
U.S. locations
16
States / cities
San Francisco, California • Iowa City, Iowa • Boston, Massachusetts + 12 more
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 9, 2026, 9:26 PM EDT
Terminated No phase listed Observational

HAART Annuloplasty Device Valve Repair Registry

NCT04035356
View directory record Official record
Conditions
Aortic Valve Insufficiency, Aortic Aneurysm
Interventions
Aortic valve repair
Device
Lead sponsor
Biostable Science & Engineering
Industry
Eligibility
Not listed
Enrollment
183 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
5
States / cities
Indianapolis, Indiana • Ann Arbor, Michigan • St Louis, Missouri + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 9, 2024 · Synced Oct 9, 2026, 9:26 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Prophylactic vs Therapeutic Cerebrospinal Fluid Drain Placement During Endovascular Thoracoabdominal Aortic Aneurysm Repair

NCT04941157
View directory record Official record
Conditions
Spinal Cord Ischemia
Interventions
Cerebrospinal Fluid Drain Placement
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 100 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
2
States / cities
Birmingham, Alabama • Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 10, 2025 · Synced Oct 9, 2026, 9:26 PM EDT
Completed No phase listed Observational Results available

Evaluation of Contrast-Enhanced Ultrasound to Detect Endoleaks After Endovascular Aortic Aneurysm Repair

NCT01005212
View directory record Official record
Conditions
Endoleaks
Interventions
Definity
Drug
Lead sponsor
E. Peden, MD
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 12, 2024 · Synced Oct 9, 2026, 9:26 PM EDT
Completed Not applicable Interventional

Prehabilitation for Aortic Aneurysm Surgery: Proof-of-concept Trial

NCT06998498
View directory record Official record
Conditions
Aortic Aneurysm
Interventions
Ready for Recovery
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 9, 2026, 9:26 PM EDT
Active, not recruiting Not applicable Interventional

Visceral Manifold Study for the Repair of TAAA

NCT03075748
View directory record Official record
Conditions
Thoracoabdominal Aortic Aneurysms
Interventions
TAAA Debranching Stent Graft System
Device
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
2
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jan 22, 2025 · Synced Oct 9, 2026, 9:26 PM EDT
Not yet recruiting Early Phase 1 Interventional

Mechanistic Clinical Trial of PCSK9 Inhibition for AAA

NCT06081153
View directory record Official record
Conditions
Abdominal Aortic Aneurysm
Interventions
Evolocumab, Placebo
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Oct 9, 2026, 9:26 PM EDT
Recruiting No phase listed Observational

Clinical Outcomes of Patients Treated With Open Surgical Repair for Complex Aortic Aneurysms

NCT03446287
View directory record Official record
Conditions
Aortic Aneurysm, Abdominal
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 23, 2026 · Synced Oct 9, 2026, 9:26 PM EDT
Completed Not applicable Interventional Results available

Post-Approval Trial of the Talent™ Abdominal Stent Graft to Treat Aortic Aneurysms

NCT00816062
View directory record Official record
Conditions
Aortic Aneurysm, Abdominal
Interventions
Talent Abdominal Stent Graft
Device
Lead sponsor
Medtronic Cardiovascular
Industry
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
18
States / cities
Los Angeles, California • Palo Alto, California • Newark, Delaware + 14 more
Source: ClinicalTrials.gov public record
Updated Oct 29, 2021 · Synced Oct 9, 2026, 9:26 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Abdominal Aorta Palpation With Point of Care Ultrasound Imaging Measurements

NCT06211946
View directory record Official record
Conditions
Physical Examination, Ultrasound Imaging, Abdominal Aortic Aneurysm
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 16, 2024 · Synced Oct 9, 2026, 9:26 PM EDT
Terminated Phase 4 Interventional Results available

Predictors of AAA Expansion and/or Rupture

NCT03231397
View directory record Official record
Conditions
Abdominal Aortic Aneurysm (AAA)
Interventions
Assess AAA rupture risk by PET-CTA scans, 18F-fludeoxyglucose (FDG), 11C-PBR28
Drug · Diagnostic Test
Lead sponsor
Washington University School of Medicine
Other
Eligibility
45 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 9, 2021 · Synced Oct 9, 2026, 9:26 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Radiation Dose From Computed Tomography Before and After Implementation of a High Pitch Dual Spiral Technique

NCT01111760
View directory record Official record
Conditions
Atherosclerosis of Coronary Artery, Cardiovascular Disease, Pulmonary Embolism, Aortic Aneurysm Without Mention of Rupture Nos
Interventions
Not listed
Lead sponsor
Michael Gallagher
Other
Eligibility
Not listed
Enrollment
334 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 5, 2013 · Synced Oct 9, 2026, 9:26 PM EDT
Completed Not applicable Interventional Results available

Valor II: The Valiant Thoracic Stent Graft System Clinical Study

NCT00413231
View directory record Official record
Conditions
Thoracic Aortic Aneurysm
Interventions
Valiant Thoracic Stent Graft System
Device
Lead sponsor
Medtronic Cardiovascular
Industry
Eligibility
18 Years to 85 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2014
U.S. locations
26
States / cities
Birmingham, Alabama • Los Angeles, California • Torrance, California + 21 more
Source: ClinicalTrials.gov public record
Updated Nov 3, 2021 · Synced Oct 9, 2026, 9:26 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Prevention of Colon Ischemia During Aortic Aneurysm (AAA) Repair

NCT00671203
View directory record Official record
Conditions
Colon Ischemia, Aortic Aneurysm
Interventions
Reestablish colon blood flow
Procedure
Lead sponsor
Spectros Corporation
Industry
Eligibility
Not listed
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
2
States / cities
Davis, California • Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Feb 1, 2011 · Synced Oct 9, 2026, 9:26 PM EDT
Completed Not applicable Interventional Results available

Zenith® Dissection Endovascular System

NCT02094300
View directory record Official record
Conditions
Aortic Dissection
Interventions
Zenith® Dissection Endovascular Graft
Device
Lead sponsor
Cook Group Incorporated
Industry
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2016
U.S. locations
5
States / cities
Gainesville, Florida • Boston, Massachusetts • Camden, New Jersey + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 6, 2017 · Synced Oct 9, 2026, 9:26 PM EDT
Completed Phase 4 Interventional Results available

Standard Open Surgery Versus Endovascular Repair of Abdominal Aortic Aneurysm (AAA)

NCT00094575
View directory record Official record
Conditions
Aortic Aneurysm
Interventions
Endovascular Repair, Standard Open Repair
Procedure
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years and older
Enrollment
881 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2012
U.S. locations
42
States / cities
Birmingham, Alabama • Tucson, Arizona • No. Little Rock, Arkansas + 39 more
Source: ClinicalTrials.gov public record
Updated Mar 7, 2016 · Synced Oct 9, 2026, 9:26 PM EDT
Terminated Not applicable Interventional Results available

Safety, Efficacy, Longitudinal Costs and Patient-Centered Outcomes Using a TAAA Debranching Device

NCT03637374
View directory record Official record
Conditions
Thoracoabdominal Aortic Aneurysm
Interventions
Visceral Manifold and Thoracic Bifurcation, Unitary Manifold, TAAA Debranching Stent Graft System
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 19, 2022 · Synced Oct 9, 2026, 9:26 PM EDT
Recruiting Phase 1 Interventional

Nicotinamide Riboside (NR) to Treat Moyamoya-like Cerebrovascular Disease in Smooth Muscle Dysfunction Syndrome (SMDS)

NCT06280482
View directory record Official record
Conditions
Smooth Muscle Dysfunction Syndrome (SMDS)
Interventions
Nicotinamide riboside (NR)
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
1 Year and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 12, 2025 · Synced Oct 9, 2026, 9:26 PM EDT
Withdrawn Not applicable Interventional

The Effects of Exercise on Quality of Life and Fluid Dynamics in Patients With Aortic Dissection

NCT05499650
View directory record Official record
Conditions
Aortic Dissection
Interventions
Supervised Exercise Regiment
Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 88 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
2
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 29, 2024 · Synced Oct 9, 2026, 9:26 PM EDT