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Conditions: Abdominal Aortic Aneurysm, Pararenal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm
Interventions: GORE® EXCLUDER® Thoracoabdominal Branch Endoprosthesis (TAMBE Device); Device
Lead sponsor: W.L.Gore & Associates; Industry
Eligibility: 18 Years and older
Enrollment: 310 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2036
U.S. locations: 1
States / cities: Stanford, California

Conditions: Inflammatory Abdominal Aortic Aneurysm, Aneurysm, Infected, Aneurysm, Mycotic, Abdominal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm
Interventions: Complex endovascular aortic repair (cEVAR); Procedure
Lead sponsor: CEVARII; Other
Eligibility: 18 Years and older
Enrollment: 220 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Vascular Ehlers-Danlos Syndrome
Interventions: Enzastaurin, Placebo; Drug
Lead sponsor: Aytu BioPharma, Inc.; Industry
Eligibility: 18 Years to 60 Years
Enrollment: 260 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Englewood, Colorado

Conditions: Aortic Aneurysm, Abdominal
Interventions: Medical imaging; Other
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years to 80 Years
Enrollment: 2 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2022
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Aortic Aneurysm, Thoracic
Interventions: Nicardipine, 0.9% saline; Drug
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Thoracic Aortic Aneurysm, Penetrating Ulcers
Interventions: Relay Thoracic Stent-Graft; Device
Lead sponsor: Bolton Medical; Industry
Eligibility: 18 Years and older
U.S. locations: 15
States / cities: Phoenix, Arizona • Washington D.C., District of Columbia • Gainesville, Florida + 12 more

Conditions: Appendicitis, Evidence of Cholecystectomy, Gallstones, Pregnancy, Ectopic, Aortic Aneurysm, Kidney Stones, Intrauterine Pregnancy, Diverticulitis, Abdominal Injuries, Tumors, Pancreatitis, Digestive System Diseases, Gastrointestinal Diseases, Intraabdominal Infections, Intestinal Diseases, Pregnancy, Vascular Disease, Uterine Fibroids, Ovarian Cysts, Uterine Abnominalies, Bladder Abnominalies, Testicular Abnominalies, Polyps
Interventions: Not listed
Lead sponsor: Duke University; Other
Eligibility: Not listed
Enrollment: 174 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2022
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Renal Aneurysm, Aneurysm Thoracic, Aneurysm Abdominal
Interventions: Complex Endovascular Aortic Procedures treated by Preloaded Fenestrated Stent-graft Designs for; Procedure
Lead sponsor: IRCCS San Raffaele; Other
Eligibility: 18 Years and older
Enrollment: 741 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 5
States / cities: Boston, Massachusetts • Worcester, Massachusetts • Dallas, Texas + 2 more

Conditions: Aortic Aneurysm, Abdominal
Interventions: Exercise Program; Behavioral
Lead sponsor: Stanford University; Other
Eligibility: 50 Years and older
Enrollment: 2,400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2011
U.S. locations: 3
States / cities: Palo Alto, California • Santa Clara, California • Stanford, California

Conditions: Thoracic Aortic Dissection
Interventions: Valiant Navion Thoracic Stent Graft System; Device
Lead sponsor: Medtronic Cardiovascular; Industry
Eligibility: 18 Years and older
Enrollment: 102 participants
Timeline: 2020 – 2024
U.S. locations: 12
States / cities: Birmingham, Alabama • Gainesville, Florida • Atlanta, Georgia + 9 more

Conditions: Endograft Implantation to Repair Abdominal Aortic Aneurysm
Interventions: Contrast Enhanced Ultrasound (Contrast Agent: OptisonTM); Procedure
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Abdominal Aortic Aneurysms, Iliac Aneurysms, Aortoiliac Aneurysms
Interventions: Zenith Low Profile AAA Endovascular Graft and ancillary components; Device
Lead sponsor: Cook Research Incorporated; Industry
Eligibility: 18 Years and older
Enrollment: 62 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2021
U.S. locations: 36
States / cities: Stanford, California • Aurora, Colorado • Hartford, Connecticut + 32 more

Conditions: Marfan Syndrome, Turner Syndrome, Ehlers-Danlos Syndrome, Loeys-Dietz Syndrome, FBN1, TGFBR1, TGFBR2, ACTA2 or MYH11 Genetic Mutation, Bicuspid Aortic Valve Without Known Family History, Bicuspid Aortic Valve With Family History, Bicuspid Aortic Valve With Coarctation, Familial Thoracic Aortic Aneurysm and Dissections, Shprintzen-Goldberg Syndrome, Other Aneur/Diss of Thoracic Aorta Not Due to Trauma, <50yo, Other Congenital Heart Disease
Interventions: Not listed
Lead sponsor: National Heart, Lung, and Blood Institute (NHLBI); NIH
Eligibility: Not listed
Enrollment: 3,706 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2016
U.S. locations: 7
States / cities: Honolulu, Hawaii • Baltimore, Maryland • New York, New York + 3 more

Conditions: AAA - Abdominal Aortic Aneurysm
Interventions: Not listed
Lead sponsor: W.L.Gore & Associates; Industry
Eligibility: 18 Years and older
Enrollment: 2,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2042
U.S. locations: 45
States / cities: Little Rock, Arkansas • Irvine, California • Los Angeles, California + 38 more

Conditions: Complex Abdominal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm, Aortic Arch Aneurysm, Aortic Arch Dissection
Interventions: CAAA and TAAA Arm, Aortic Arch Aneurysm Arm; Device
Lead sponsor: Gustavo S Oderich; Other
Eligibility: 18 Years and older
Enrollment: 760 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2032
U.S. locations: 3
States / cities: Rochester, Minnesota • Houston, Texas

Conditions: Aorta Aneurysm, Dissection of Aorta
Interventions: Clevidipine; Drug
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 80 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Aneurysm, Dissection, Aortic Root Aneurysm, Aortic Root Dissection, Carotid Artery Injuries, Aortic Arch, Bypass Extremity Graft, Occlusive Vascular Disease, Aortic Diseases
Interventions: Gelsoft Plus Vascular Graft, Vascular Bypass Graft, Cardiovascular Patch, Gelweave Vascular Graft, Gelweave Valsalva Vascular Graft; Device
Lead sponsor: Vascutek Ltd.; Industry
Eligibility: 18 Years and older
Enrollment: 2,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2037
U.S. locations: 10
States / cities: Aurora, Colorado • Tampa, Florida • Indianapolis, Indiana + 7 more

Conditions: Abdominal Aortic Aneurysm
Interventions: Evolocumab, Placebo; Drug
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Thoracic Aneurysm, Aneurysm Stent, Cardiopulmonary Bypass, Abdominal Aneurysm
Interventions: Propofol, isoflurane; Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: 21 Years to 100 Years
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Complex Abdominal Aortic Aneurysm
Interventions: Fenerated AAA Endovascular Graft with H&L-B One Shot Introduction System; Device
Lead sponsor: NYU Langone Health; Other
Eligibility: 70 Years to 70 Years · Male only
U.S. locations: 1
States / cities: New York, New York

Conditions: Thoracic Aortic Aneurysms
Interventions: Talent Thoracic Stent Graft System; Device
Lead sponsor: Medtronic Cardiovascular; Industry
Eligibility: 18 Years and older
Enrollment: 349 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2017
U.S. locations: 26
States / cities: Los Angeles, California • Torrance, California • Washington D.C., District of Columbia + 22 more

Conditions: Juxtarenal Aortic Aneurysms, Suprarenal Aortic Aneurysms, Type IV Thoracoabdominal Aortic Aneurysms
Interventions: Custom-made Zenith® Fenestrated AAA Endovascular Graft:; Device
Lead sponsor: Gustavo S Oderich; Other
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2030
U.S. locations: 2
States / cities: Rochester, Minnesota • Houston, Texas

Conditions: Chest Pain, Acute Coronary Syndrome, Pulmonary Embolism, Aortic Dissection
Interventions: Not listed
Lead sponsor: University of Washington; Other
Eligibility: 30 Years and older
Enrollment: 102 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Intracranial Aneurysm, Abdominal Aortic Aneurysm
Interventions: Imaging-Ultrasound, Imaging-MRA, DNA, RNA testing; Other · Genetic
Lead sponsor: University of Virginia; Other
Eligibility: 18 Years and older
Enrollment: 360 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2014
U.S. locations: 1
States / cities: Charlottesville, Virginia

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GORE® EXCLUDER® Thoracoabdominal Branch Endoprosthesis Post-Approval Study

Complex EVAR in Inflammatory and Infective Abdominal and Thoracoabdominal Aortic Aneurysms

Investigate Efficacy, Safety, and Pharmacokinetics of Enzastaurin for the Prevention of Arterial Events in Patients With Vascular Ehlers-Danlos Syndrome.

Predicting Rupture of AAA by Anatomic and Hemodynamic Markers

NICardipine Neuroprotection in AortiC Surgery (NICNACS)

Phase II Clinical Study of the Safety and Efficacy of the Relay Thoracic Stent-Graft

Point of Care 3D Ultrasound for Various Applications: A Pilot Study

Registry of Patients Treated by Preloaded Fenestrated Stent-graft Designs for Complex Endovascular Aortic Procedures

Exercise Therapy to Treat Adults With Abdominal Aortic Aneurysms

DISSECT-N Post Market Data Collection Registry

Contrast Enhanced Ultrasound vs. Computed Tomographic Angiography in the Detection of Endoleaks Following AAA Repair

Zenith® Low Profile AAA Endovascular Graft

National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions

Endovascular AAA Intervention Using the GORE® EXCLUDER® Conformable AAA Endoprosthesis or Iliac Branch Endoprosthesis

CAAAs, TAAAs, Aortic Arch Aneurysms or Dissections With Fenestrated/Branched Stent Graft

Pre and or Post Operative Blood Pressure Control With Clevidipine (Cleviprexm Medicines Company) in Aortic Aneurysm / Dissection

PANTHER Study of Terumo Aortic Knitted and Woven Grafts, and Cardiovascular Patches

Mechanistic Clinical Trial of PCSK9 Inhibition for AAA

The Effects of Anesthesia on Patients Undergoing Surgery for Repair of a Thoracoabdominal Aneurysm.

Compassionate Use Treatment for a Single Patient With a Custom Made Branched/Fenestrated Endovascular Device for the Treatment of Complex Abdominal Aortic Aneurysm

Post-Approval Clinical Study of the Talent Thoracic Stent Graft to Treat Thoracic Aortic Aneurysms (THRIVE)

Complex Abdominal Aortic Aneurysm Repair With Fenestrated Stent Grafts

Diagnostic Accuracy of Multislice CT Angiography for Acute Chest Pain

UVA Brain and Aortic Aneurysm Study