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Showing 1–24 of 764 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Aortic Diseases Clear all
Completed Not applicable Interventional

High Intensity Exercise for Increasing Fitness in Patients With Hypertrophic Cardiomyopathy

NCT03335332
View directory record Official record
Conditions
Hypertrophic Cardiomyopathy
Interventions
High intensity exercise, Moderate intensity exercise
Behavioral
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Feb 27, 2023 · Synced Jun 25, 2026, 3:52 PM EDT
Recruiting No phase listed Observational

Pediatric Cardiomyopathy Mutation Analysis

NCT02432092
View directory record Official record
Conditions
Cardiomyopathies, Dilated Cardiomyopathy, Hypertrophic Cardiomyopathy, Restrictive Cardiomyopathy, Arrhythmogenic Right Ventricular Cardiomyopathy, Left Ventricular Non-compaction Cardiomyopathy
Interventions
Not listed
Lead sponsor
Indiana University
Other
Eligibility
Not listed
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2030
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 21, 2026 · Synced Jun 25, 2026, 3:52 PM EDT
Not listed Phase 1 Interventional

Cisplatin and Radiation Therapy Followed by Paclitaxel and Carboplatin in Treating Patients With Stage IB-IVA Cervical Cancer

NCT01295502
View directory record Official record
Conditions
Cervical Adenocarcinoma, Cervical Adenosquamous Carcinoma, Cervical Squamous Cell Carcinoma, Not Otherwise Specified, Stage IB Cervical Cancer AJCC v6 and v7, Stage IIA Cervical Cancer AJCC v7, Stage IIB Cervical Cancer AJCC v6 and v7, Stage IIIA Cervical Cancer AJCC v6 and v7, Stage IIIB Cervical Cancer AJCC v6 and v7, Stage IVA Cervical Cancer AJCC v6 and v7
Interventions
Carboplatin, Cisplatin, External Beam Radiation Therapy, Internal Radiation Therapy, Paclitaxel
Drug · Radiation
Lead sponsor
Gynecologic Oncology Group
Network
Eligibility
18 Years and older · Female only
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2011
U.S. locations
14
States / cities
Orange, California • Hartford, Connecticut • New Britain, Connecticut + 9 more
Source: ClinicalTrials.gov public record
Updated Mar 11, 2019 · Synced Jun 25, 2026, 3:52 PM EDT
Recruiting Not applicable Interventional

CAAAs, TAAAs, Aortic Arch Aneurysms or Dissections With Fenestrated/Branched Stent Graft

NCT02089607
View directory record Official record
Conditions
Complex Abdominal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm, Aortic Arch Aneurysm, Aortic Arch Dissection
Interventions
CAAA and TAAA Arm, Aortic Arch Aneurysm Arm
Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older
Enrollment
760 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2032
U.S. locations
3
States / cities
Rochester, Minnesota • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 19, 2026 · Synced Jun 25, 2026, 3:52 PM EDT
Recruiting Not applicable Interventional

Quantification of Debris Captured Using TCEP During VIV TAVR With BVF

NCT05093764
View directory record Official record
Conditions
Aortic Valve Disease
Interventions
VIV TAVR with BVF using TCEP
Device
Lead sponsor
Saint Luke's Health System
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 13, 2024 · Synced Jun 25, 2026, 3:52 PM EDT
Completed Not applicable Interventional Results available

Home-Based Exercise Program For Recovery After Transcatheter Aortic Valve Replacement

NCT02805309
View directory record Official record
Conditions
Aortic Valve Stenosis
Interventions
Exercise, Cognitive behavioral interventions, Attention control education program
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
65 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
3
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 20, 2021 · Synced Jun 25, 2026, 3:52 PM EDT
Completed Not applicable Interventional Results available

Safety and Effectiveness Study of Endovascular Abdominal Aortic Aneurysm Repair Using the Nellix® System

NCT01726257
View directory record Official record
Conditions
Abdominal Aortic Aneurysm (AAA)
Interventions
Nellix System
Device
Lead sponsor
Endologix
Industry
Eligibility
18 Years and older
Enrollment
333 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2022
U.S. locations
27
States / cities
Tucson, Arizona • San Diego, California • New Haven, Connecticut + 23 more
Source: ClinicalTrials.gov public record
Updated Feb 27, 2025 · Synced Jun 25, 2026, 3:52 PM EDT
Completed Not applicable Interventional

Impact of a Patient Decision Aid for Treatment of Aortic Stenosis

NCT04103931
View directory record Official record
Conditions
Aortic Valve Stenosis
Interventions
"Treatment Choices for Aortic Stenosis" Decision Aid
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 85 Years
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
2
States / cities
Aurora, Colorado • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 4, 2022 · Synced Jun 25, 2026, 3:52 PM EDT
Not listed Phase 3 Interventional

The Use of Nesiritide in Thoracic Aneurysm Repair to Prevent Acute Renal Failure

NCT00110201
View directory record Official record
Conditions
Cardiovascular Disease, Acute Renal Failure, Death
Interventions
Nesiritide
Drug
Lead sponsor
Ejaz, Abulate A, MD
Individual
Eligibility
18 Years and older
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 23, 2005 · Synced Jun 25, 2026, 3:52 PM EDT
Completed Not applicable Interventional Results available

Surgical Treatment of Aortic Stenosis With a Next Generation, Rapid Deployment Surgical Aortic Valve

NCT01700439
View directory record Official record
Conditions
Aortic Valve Stenosis, Aortic Valve Stenosis With Insufficiency, Regurgitation, Aortic Valve, Aortic Valve Incompetence
Interventions
EDWARDS INTUITY valve
Device
Lead sponsor
Edwards Lifesciences
Industry
Eligibility
18 Years and older
Enrollment
934 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2021
U.S. locations
29
States / cities
Los Angeles, California • Newport Beach, California • Palo Alto, California + 24 more
Source: ClinicalTrials.gov public record
Updated May 18, 2023 · Synced Jun 25, 2026, 3:52 PM EDT
Terminated Phase 2 Interventional Results available

A Phase II Study of Extended Field IMRT External Beam Irradiation and Intracavitary Brachytherapy

NCT00590967
View directory record Official record
Conditions
Cervical Cancer
Interventions
IMRT extended field external beam radiation therapy, Brachytherapy, Cisplatin
Radiation · Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older · Female only
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2013
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 28, 2016 · Synced Jun 25, 2026, 3:52 PM EDT
Active, not recruiting Not applicable Interventional

PERSEVERE- A Trial to Evaluate AMDS in Acute DeBakey Type I Dissection

NCT05174767
View directory record Official record
Conditions
Acute Aortic Dissection
Interventions
AMDS
Device
Lead sponsor
Artivion Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2029
U.S. locations
25
States / cities
Birmingham, Alabama • Los Angeles, California • Palo Alto, California + 20 more
Source: ClinicalTrials.gov public record
Updated Jan 14, 2025 · Synced Jun 25, 2026, 3:52 PM EDT
Recruiting Not applicable Interventional

ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves

NCT05172973
View directory record Official record
Conditions
Aortic Valve Insufficiency, Aortic Valve Stenosis
Interventions
SAPIEN X4 THV
Device
Lead sponsor
Edwards Lifesciences
Industry
Eligibility
Not listed
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2036
U.S. locations
32
States / cities
Newport Beach, California • San Francisco, California • Stanford, California + 25 more
Source: ClinicalTrials.gov public record
Updated Dec 21, 2025 · Synced Jun 25, 2026, 3:52 PM EDT
Completed No phase listed Observational

Diagnostic Accuracy of Multislice CT Angiography for Acute Chest Pain

NCT00855231
View directory record Official record
Conditions
Chest Pain, Acute Coronary Syndrome, Pulmonary Embolism, Aortic Dissection
Interventions
Not listed
Lead sponsor
University of Washington
Other
Eligibility
30 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Nov 26, 2017 · Synced Jun 25, 2026, 3:52 PM EDT
Terminated No phase listed Observational

Surgical Outcomes in Pediatric Patients With Coarctation and VSD

NCT00327795
View directory record Official record
Conditions
Diagnosis of Coarctation of the Aorta and VSD, Surgical Repair at CHOA, Between January 1, 2002 and December 31, 2005
Interventions
Not listed
Lead sponsor
Children's Healthcare of Atlanta
Other
Eligibility
Not listed
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 15, 2012 · Synced Jun 25, 2026, 3:52 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Loss of Y Chromosome in Aortic Stenosis

NCT06595407
View directory record Official record
Conditions
Aortic Stenosis
Interventions
Blood analysis for loss-of-Y chromosome
Diagnostic Test
Lead sponsor
University of Virginia
Other
Eligibility
40 Years and older · Male only
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Jun 25, 2026, 3:52 PM EDT
Completed Not applicable Interventional Results available

Study to Determine if the Valiant Stent Graft is Safe and Effective in Treating Patients Who Have a Blunt Thoracic Aortic Injury

NCT01092767
View directory record Official record
Conditions
Blunt Thoracic Aortic Injury
Interventions
Valiant Thoracic Stent Graft with the Captivia Delivery System
Device
Lead sponsor
Medtronic Cardiovascular
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
23
States / cities
Birmingham, Alabama • Los Angeles, California • Torrance, California + 20 more
Source: ClinicalTrials.gov public record
Updated Oct 28, 2021 · Synced Jun 25, 2026, 3:52 PM EDT
Active, not recruiting No phase listed Observational

Stress Aortic Valve Index for Assessing Risk in Aortic Valve Stenosis Patients

NCT04514250
View directory record Official record
Conditions
Aortic Valve Stenosis
Interventions
Not listed
Lead sponsor
Catharina Ziekenhuis Eindhoven
Other
Eligibility
50 Years and older
Enrollment
52 participants
Timeline
2021 – 2028
U.S. locations
2
States / cities
Worcester, Massachusetts • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 13, 2024 · Synced Jun 25, 2026, 3:52 PM EDT
Completed Phase 4 Interventional Results available

Effect of Carvedilol Controlled-Release (CR) and Atenolol on Central Blood Pressure

NCT00669279
View directory record Official record
Conditions
Hypertension
Interventions
Carvedilol CR, Atenolol
Drug
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 4, 2017 · Synced Jun 25, 2026, 3:52 PM EDT
Completed No phase listed Observational

Inflammation and Risk Prediction in Patients With Abdominal Aortic Aneurysm

NCT00513773
View directory record Official record
Conditions
Aortic Aneurysm, Abdominal
Interventions
Not listed
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 6, 2017 · Synced Jun 25, 2026, 3:52 PM EDT
Not listed Not applicable Interventional

Acute Technical Outcomes of the Talent Abdominal Aortic Aneurysm (AAA) Stent-Graft Versus Cook Zenith Stent-Graft

NCT00922454
View directory record Official record
Conditions
Abdominal Aortic Aneurysm
Interventions
Endovascular Repair of the abdominal aorta, Cook Zenith Stent-Graft, Talent Stent-Graft
Procedure · Device
Lead sponsor
Center for Vascular Awareness, Albany, New York
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Jun 16, 2009 · Synced Jun 25, 2026, 3:52 PM EDT
Withdrawn Not applicable Interventional

The Effects of Exercise on Quality of Life and Fluid Dynamics in Patients With Aortic Dissection

NCT05499650
View directory record Official record
Conditions
Aortic Dissection
Interventions
Supervised Exercise Regiment
Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 88 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
2
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 28, 2024 · Synced Jun 25, 2026, 3:52 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Acute Dietary Supplementation With Grape Seed Extract on Aortic Stiffness, Arterial Pressure, and Blood Vessel Dilation in Collegiate Obese Individuals at Rest

NCT04389060
View directory record Official record
Conditions
Obesity
Interventions
Grape seed extract
Dietary Supplement
Lead sponsor
California Baptist University
Other
Eligibility
18 Years to 29 Years · Male only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Riverside, California
Source: ClinicalTrials.gov public record
Updated May 14, 2020 · Synced Jun 25, 2026, 3:52 PM EDT
Completed No phase listed Observational

Mavacamten in Obstructive Hypertrophic Cardiomyopathy

NCT07168655
View directory record Official record
Conditions
Obstructive Hypertrophic Cardiomyopathy (oHCM)
Interventions
Mavacamten
Drug
Lead sponsor
Bristol-Myers Squibb
Industry
Eligibility
18 Years and older
Enrollment
163 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 10, 2025 · Synced Jun 25, 2026, 3:52 PM EDT