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Showing 1–21 of 21 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Aphasia, Acquired Clear all
Completed Not applicable Interventional Results available

Treatment Intensity - Apraxia of Speech

NCT02332915
View directory record Official record
Conditions
Aphasia, CVA, Apraxia of Speech
Interventions
Sound Production Treatment (SPT)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 90 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 11, 2022 · Synced Jun 10, 2026, 5:02 AM EDT
Completed Not applicable Interventional

Effects of High-intensity Exercise Training on Physical Fitness, Cognition, Language in Post-stroke Aphasia

NCT06185023
View directory record Official record
Conditions
Aphasia, Acquired, Aphasia, Aphasia, Fluent, Aphasia Non Fluent
Interventions
Low-intensity physical exercise, High-intensity physical exercise
Behavioral
Lead sponsor
University of California, Berkeley
Other
Eligibility
18 Years to 80 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
4
States / cities
Berkeley, California • Hayward, California • San Francisco, California
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Jun 10, 2026, 5:02 AM EDT
Recruiting Phase 2 Interventional

Transcranial Magnetic Stimulation + Language Therapy to Treat Mild Aphasia

NCT06842745
View directory record Official record
Conditions
Aphasia, Stroke, Aphasia Following Cerebral Infarction, Aphasia, Acquired
Interventions
Transcranial Magnetic Stimulation (TMS), Speech-Language Therapy (SLT)
Device · Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
40 Years to 85 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Jun 10, 2026, 5:02 AM EDT
Recruiting Phase 2 Interventional

Comparing Traditional Semantic Feature Analysis (tSFA) and Semantic Feature Analysis + Metacognitive Strategy Training (SFA+MST)

NCT07036406
View directory record Official record
Conditions
Aphasia, Aphasia Following Cerebral Infarction, Aphasia, Acquired, Aphasia, Rehabilitation, Aphasia, Anomic, Aphasia, Broca, Aphasia, Conduction, Aphasia, Expressive, Aphasia Non Fluent, Aphasia, Mixed
Interventions
Semantic Feature Analysis (traditional), Semantic Feature Analysis + Metacognitive Strategy Training
Behavioral
Lead sponsor
Teachers College, Columbia University
Other
Eligibility
18 Years to 89 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 11, 2025 · Synced Jun 10, 2026, 5:02 AM EDT
Active, not recruiting Not applicable Interventional

Conversation Group Treatment for Aphasia: Does it Work?

NCT05113160
View directory record Official record
Conditions
Aphasia, Acquired
Interventions
Conversation Treatment for Aphasia
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years to 85 Years
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
3
States / cities
Boston, Massachusetts • Maywood, New Jersey • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 5, 2025 · Synced Jun 10, 2026, 5:02 AM EDT
Completed Not applicable Interventional

Therapy for Reading Problems in Adults After Brain Injury

NCT00064805
View directory record Official record
Conditions
Dyslexia, Acquired, Brain Injuries, Cerebrovascular Accident
Interventions
Cognitive Therapy to Improve Reading
Behavioral
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2007
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Aug 14, 2014 · Synced Jun 10, 2026, 5:02 AM EDT
Completed Not applicable Interventional Results available

Treatments of Acquired Apraxia of Speech

NCT01483807
View directory record Official record
Conditions
Aphasia, Apraxia of Speech, Stroke
Interventions
Sound Production Treatment - Blocked, Sound Production Treatment - Random
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Mar 21, 2019 · Synced Jun 10, 2026, 5:02 AM EDT
Completed Not applicable Interventional Results available

Dosage and Predictors of Naming Treatment Response in Aphasia

NCT02005016
View directory record Official record
Conditions
Aphasia, Stroke
Interventions
Naming therapy
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 85 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 3, 2019 · Synced Jun 10, 2026, 5:02 AM EDT
Completed Not applicable Interventional Results available

Word Retrieval in the Wild in People With Post-Stroke Aphasia

NCT05338216
View directory record Official record
Conditions
Aphasia, Acquired
Interventions
Traditional EMA, Micro-Interaction EMA
Behavioral
Lead sponsor
Northeastern University
Other
Eligibility
18 Years to 89 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 7, 2025 · Synced Jun 10, 2026, 5:02 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Enhancing Language Function in Aphasia

NCT05443633
View directory record Official record
Conditions
Aphasia, Acquired, Language Disorders, Primary Progressive Aphasia, Stroke, Cerebrovascular
Interventions
individualized speech-language training, standard language intervention
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
21 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2028
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Dec 8, 2024 · Synced Jun 10, 2026, 5:02 AM EDT
Completed Not applicable Interventional

Effect of Participation in Virtual Exercise Sessions in Persons With Aphasia

NCT05455463
View directory record Official record
Conditions
Aphasia, Acquired
Interventions
Online aphasia-adapted physical activity class
Behavioral
Lead sponsor
California State University, East Bay
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Hayward, California
Source: ClinicalTrials.gov public record
Updated Feb 5, 2024 · Synced Jun 10, 2026, 5:02 AM EDT
Not listed Not applicable Interventional

Narrative Comprehension by People With Acquired Brain Injury

NCT03309930
View directory record Official record
Conditions
Aphasia, Traumatic Brain Injury
Interventions
Comprehension Acquired Brain Injury
Behavioral
Lead sponsor
Miami University
Other
Eligibility
19 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Oxford, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 15, 2017 · Synced Jun 10, 2026, 5:02 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Neurocognitive Mechanisms of Sentence Production Impairment in Aphasia

NCT06405594
View directory record Official record
Conditions
Aphasia, Acquired, Stroke, Healthy Aging
Interventions
Language Condition
Behavioral
Lead sponsor
University of Maryland, College Park
Other
Eligibility
18 Years and older
Enrollment
350 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
College Park, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 2, 2024 · Synced Jun 10, 2026, 5:02 AM EDT
Completed Not applicable Interventional Results available

Apraxia of Speech: Comparison of EPG Treatment (Tx) and Sound Production Treatment (SPT)

NCT02554513
View directory record Official record
Conditions
Apraxia of Speech, Aphasia, Acquired, Speech Disorders
Interventions
EPG Tx, SPT
Device · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 80 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Nov 3, 2021 · Synced Jun 10, 2026, 5:02 AM EDT
Completed Not applicable Interventional

Speech Entrainment Treatment for People With Aphasia

NCT05687994
View directory record Official record
Conditions
Aphasia, Acquired
Interventions
Audiovisual Speech Entrainment Practice, Auditory Speech Entrainment Practice
Behavioral
Lead sponsor
Albert Einstein Healthcare Network
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Elkins Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 17, 2025 · Synced Jun 10, 2026, 5:02 AM EDT
Active, not recruiting Not applicable Interventional

Impact of Group Participation on Adults With Aphasia

NCT05520528
View directory record Official record
Conditions
Aphasia, Acquired, Stroke, Rehabilitation, Language Disorder, Acquired
Interventions
Language intervention with group sessions and independent tasks with emphasis on improving reading and writing skills among persons with aphasia
Behavioral
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Jul 2, 2025 · Synced Jun 10, 2026, 5:02 AM EDT
Completed Not applicable Interventional

Multimodal Treatment of Phonological Alexia: Behavioral & fMRI Outcomes

NCT00827268
View directory record Official record
Conditions
Aphasia, Stroke, Dyslexia, Acquired
Interventions
One-on-one treatment of reading difficulties
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 29, 2017 · Synced Jun 10, 2026, 5:02 AM EDT
Completed Not applicable Interventional Results available

Effects of rTMS on Brain Activation in Aphasia

NCT03292471
View directory record Official record
Conditions
Aphasia, Acquired
Interventions
Transcranial Magnetic Stimulation
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 19, 2022 · Synced Jun 10, 2026, 5:02 AM EDT
Completed Phase 2 Interventional

PCT for Speech, Language, and Cognitive Intervention in Stroke Patients

NCT04488029
View directory record Official record
Conditions
Aphasia, Acquired
Interventions
PCT, Workbooks
Other
Lead sponsor
The Learning Corp
Industry
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Newton, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 26, 2020 · Synced Jun 10, 2026, 5:02 AM EDT
Recruiting Not applicable Interventional

Aphasia Physical EXercise Study: Randomized Trial

NCT07281313
View directory record Official record
Conditions
Aphasia, Acquired, Aphasia, Aphasia, Fluent, Aphasia, Non-fluent, Aphasia Following Cerebral Infarction, Aphasia Following Nontraumatic Intracerebral Hemorrhage
Interventions
High-intensity physical exercise, Low-intensity physical exercise
Behavioral
Lead sponsor
University of California, Berkeley
Other
Eligibility
18 Years to 80 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
4
States / cities
Berkeley, California • Hayward, California • San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Jun 10, 2026, 5:02 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

tACS to Enhance Language Abilities

NCT06092814
View directory record Official record
Conditions
Stroke, Aphasia, Acquired, Aphasia
Interventions
Active transcranial alternating current stimulation (tACS)
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 85 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 7, 2025 · Synced Jun 10, 2026, 5:02 AM EDT