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Showing 1–24 of 34 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Aphasia, Rehabilitation Clear all
Completed Phase 2Phase 3 Interventional Results available

Augmenting Language Therapy for Aphasia: Levodopa

NCT01429077
View directory record Official record
Conditions
Nonfluent Aphasia, Stroke
Interventions
levodopa/carbidopa, Placebo comparator
Drug
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
21 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 24, 2013 · Synced Sep 21, 2026, 4:45 AM EDT
Completed Not applicable Interventional

Improving Electronic Written Communication in Aphasia

NCT03773419
View directory record Official record
Conditions
Aphasia
Interventions
Texting Intervention (T-WRITE), HandWriting Intervention (ORLA+WTG)
Behavioral
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
2
States / cities
Chicago, Illinois • Harrisonburg, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 25, 2022 · Synced Sep 21, 2026, 4:45 AM EDT
Completed Phase 1 Interventional

Transcranial Direct Current Stimulation and Aphasia Language Therapy

NCT01486654
View directory record Official record
Conditions
Nonfluent Aphasia, Stroke
Interventions
Transcranial Direct Current Stimulation - Cathodal stimulation, Transcranial Direct Current Stimulation - Anodal stimulation, Transcranial Direct Current Stimulation - Sham stimulation
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
21 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 14, 2017 · Synced Sep 21, 2026, 4:45 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Treating Intention In Aphasia: Neuroplastic Substrates

NCT00567242
View directory record Official record
Conditions
Aphasia, Cerebrovascular Accident
Interventions
Word-finding with intention component, Word-finding with no intention component
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 95 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
3
States / cities
Gainesville, Florida • Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated May 2, 2012 · Synced Sep 21, 2026, 4:45 AM EDT
Recruiting Phase 2 Interventional

Comparing Traditional Semantic Feature Analysis (tSFA) and Semantic Feature Analysis + Metacognitive Strategy Training (SFA+MST)

NCT07036406
View directory record Official record
Conditions
Aphasia, Aphasia Following Cerebral Infarction, Aphasia, Acquired, Aphasia, Rehabilitation, Aphasia, Anomic, Aphasia, Broca, Aphasia, Conduction, Aphasia, Expressive, Aphasia Non Fluent, Aphasia, Mixed
Interventions
Semantic Feature Analysis (traditional), Semantic Feature Analysis + Metacognitive Strategy Training
Behavioral
Lead sponsor
Teachers College, Columbia University
Other
Eligibility
18 Years to 89 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Sep 21, 2026, 4:45 AM EDT
Completed Not applicable Interventional Results available

Speech Therapy for Aphasia: Comparing Two Treatments

NCT02153710
View directory record Official record
Conditions
Stroke
Interventions
Semantic Feature Analysis therapy, Phonomotor Therapy
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 5, 2019 · Synced Sep 21, 2026, 4:45 AM EDT
Terminated Not applicable Interventional Results available

Strategy Training for People With Aphasia After Stroke

NCT03593876
View directory record Official record
Conditions
Strategy Training
Interventions
Strategy Training
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 23, 2021 · Synced Sep 21, 2026, 4:45 AM EDT
Completed Not applicable Interventional Results available

Exercise as an Adjuvant to Aphasia Therapy

NCT01113879
View directory record Official record
Conditions
Aphasia
Interventions
Aerobic exercise, Stretching
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
20 Years to 95 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
2
States / cities
Gainesville, Florida • Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 21, 2019 · Synced Sep 21, 2026, 4:45 AM EDT
Completed No phase listed Observational

Role of the Right Brain in Recovery of Language Function in Chronic Stroke

NCT00076479
View directory record Official record
Conditions
Aphasia, Cerebrovascular Accident
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Sep 21, 2026, 4:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of the Effects of Response Elaboration Training for Aphasia

NCT00125216
View directory record Official record
Conditions
Aphasia, Language Disorders, Speech Disorders
Interventions
Response Elaboration Training
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
21 Years and older
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2012
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 6, 2014 · Synced Sep 21, 2026, 4:45 AM EDT
Completed Not applicable Interventional

Aphasia Rehabilitation: Modulating Cues, Feedback & Practice

NCT01597037
View directory record Official record
Conditions
Aphasia, Stroke
Interventions
Script training
Behavioral
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 80 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 29, 2018 · Synced Sep 21, 2026, 4:45 AM EDT
Completed Not applicable Interventional

Cognitive Therapy to Improve Word Finding

NCT00494520
View directory record Official record
Conditions
Anomia, Aphasia, Traumatic Brain Injury, Cerebrovascular Accident
Interventions
Errorful training condition, Errorless training condition
Procedure
Lead sponsor
Georgetown University
Other
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Sep 18, 2017 · Synced Sep 21, 2026, 4:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Overcoming Learned Non-Use in Chronic Aphasia

NCT02012374
View directory record Official record
Conditions
Stroke-induced Aphasia
Interventions
Intensive Language Action Therapy
Behavioral
Lead sponsor
University of Massachusetts, Amherst
Other
Eligibility
21 Years to 90 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Amherst, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 19, 2022 · Synced Sep 21, 2026, 4:45 AM EDT
Completed Not applicable Interventional

NOn-invasive Repeated THerapeutic STimulation for Aphasia Recovery

NCT02020421
View directory record Official record
Conditions
Aphasia
Interventions
rTMS, tDCS, Sham rTMS, Sham tDCS
Device
Lead sponsor
Dr. Alexander Thiel
Individual
Eligibility
50 Years to 85 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
White Plains, New York
Source: ClinicalTrials.gov public record
Updated Oct 25, 2021 · Synced Sep 21, 2026, 4:45 AM EDT
Completed Not applicable Interventional

An Investigation of Constraint Induced Language Therapy for Aphasia

NCT00223847
View directory record Official record
Conditions
Aphasia, Stroke
Interventions
Constraint Induced Language Therapy
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2006
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 31, 2008 · Synced Sep 21, 2026, 4:45 AM EDT
Not listed Not applicable Interventional

Predicting Rehabilitation Outcomes in Bilingual Aphasia Using Computational Modeling

NCT02916524
View directory record Official record
Conditions
Aphasia
Interventions
Semantic Feature Analysis (SFA)
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years to 85 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
3
States / cities
San Francisco, California • Boston, Massachusetts • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Apr 18, 2021 · Synced Sep 21, 2026, 4:45 AM EDT
Recruiting Not applicable Interventional

Telerehabilitation for Aphasia (TERRA)

NCT04682223
View directory record Official record
Conditions
Aphasia, Stroke, Stroke Rehabilitation
Interventions
Semantically-focused therapy tasks, Phonologically-focused therapy tasks
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
21 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Sep 21, 2026, 4:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Word-Retrieval Treatment for Aphasia: Semantic Feature Analysis

NCT00125242
View directory record Official record
Conditions
Aphasia, Language Disorders, Speech Disorders
Interventions
Semantic Feature Analysis (SFA)Training
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
21 Years to 80 Years
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2013
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Dec 23, 2014 · Synced Sep 21, 2026, 4:45 AM EDT
Completed Not applicable Interventional Results available

Prism Adaptation in Left Brain Stroke

NCT04387162
View directory record Official record
Conditions
Aphasia, Spatial Neglect, Stroke
Interventions
Prism Adaptation Treatment
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 89 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 8, 2025 · Synced Sep 21, 2026, 4:45 AM EDT
Completed Not applicable Interventional

Enhancing Written Communication in Persons With Aphasia

NCT01790880
View directory record Official record
Conditions
Aphasia, Stroke
Interventions
ORLA, ORLA + Writing
Behavioral
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 17, 2020 · Synced Sep 21, 2026, 4:45 AM EDT
Completed Not applicable Interventional

Treatment for Word Retrieval Impairments in Aphasia

NCT00764400
View directory record Official record
Conditions
Stroke
Interventions
Word Retrieval Treatments for Aphasia
Behavioral
Lead sponsor
Old Dominion University
Other
Eligibility
21 Years to 90 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 5, 2018 · Synced Sep 21, 2026, 4:45 AM EDT
Recruiting Phase 2Phase 3 Interventional

Superiority Trial of Aphasia-focused Rehabilitation With tDCS Stimulation

NCT07688551
View directory record Official record
Conditions
Aphasia, Broca's Aphasia
Interventions
tDCS
Device
Lead sponsor
University of South Carolina
Other
Eligibility
25 Years to 80 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
3
States / cities
Charleston, South Carolina • Columbia, South Carolina • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Sep 21, 2026, 4:45 AM EDT
Recruiting Not applicable Interventional

Cerebellar Stimulation for Aphasia Rehabilitation

NCT05093673
View directory record Official record
Conditions
Stroke
Interventions
Cathodal Cerebellar tDCS, Semantic Feature Analysis (SFA), Sham
Device · Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 99 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Sep 21, 2026, 4:45 AM EDT
Completed Phase 1 Interventional

Assessment of Cortical Stimulation Combined With Rehabilitation to Enhance Recovery in Broca's Aphasia.

NCT00170703
View directory record Official record
Conditions
Stroke, Broca's Aphasia
Interventions
Cortical Electrical Stimulation
Device
Lead sponsor
Northstar Neuroscience
Industry
Eligibility
21 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
2
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 20, 2007 · Synced Sep 21, 2026, 4:45 AM EDT