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ClinicalTrials.gov public records Last synced Sep 9, 2026, 11:38 PM EDT

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Showing 1–24 of 814 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Apnea, Obstructive Sleep Clear all
Completed Not applicable Interventional Results available

Non-Inferiority Study of the FRESCA Airbox Positive Airway Pressure System

NCT03999944
View directory record Official record
Conditions
Sleep Apnea
Interventions
positive airway pressure system
Device
Lead sponsor
FRESCA Medical
Industry
Eligibility
22 Years to 75 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
6
States / cities
St. Petersburg, Florida • Atlanta, Georgia • Gainesville, Georgia + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 22, 2021 · Synced Sep 9, 2026, 11:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Tailored Treatment to Enhance Risk Perception in Sleep Apnea

NCT02314858
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
Brief Personalized Video (BPV), Non-Personalized Video (NPV), Treatment as Usual (TAU)
Behavioral
Lead sponsor
National Jewish Health
Other
Eligibility
21 Years to 80 Years
Enrollment
284 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2021
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 29, 2021 · Synced Sep 9, 2026, 11:38 PM EDT
Withdrawn Not applicable Interventional

Intraoperative Identification and Stimulation of the Glossopharyngeal Nerve

NCT05754216
View directory record Official record
Conditions
Head and Neck Cancer, Obstructive Sleep Apnea
Interventions
Nerve stimulation using nerve stimulation device and sterile wire electrode.
Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 30, 2025 · Synced Sep 9, 2026, 11:38 PM EDT
Completed Not applicable Interventional

The Effect of Mouth Closure on Airflow in OSA

NCT06547658
View directory record Official record
Conditions
Hypopnea, Sleep
Interventions
Mouth closure
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 89 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Sep 9, 2026, 11:38 PM EDT
Completed Not applicable Interventional

Nocturnal Hypertension and Non-Dipping Blood Pressure

NCT03128177
View directory record Official record
Conditions
Hypertension, Obstructive Sleep Apnea
Interventions
Dietary sodium
Dietary Supplement
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
48 Years to 65 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 10, 2020 · Synced Sep 9, 2026, 11:38 PM EDT
Completed Not applicable Interventional Results available

Group-based Peer Support Versus Individual Education for Patients Undergoing CPAP Treatment

NCT02538419
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
CPAP + Peer Support, CPAP + Individual Education
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 20, 2019 · Synced Sep 9, 2026, 11:38 PM EDT
Recruiting Not applicable Interventional

Type 1 Diabetes and Obstructive Sleep Apnea

NCT06915831
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Type 1 Diabetes (T1D)
Interventions
Continuous positive airway pressure (CPAP)
Device
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 50 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 19, 2026 · Synced Sep 9, 2026, 11:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sleep Apnea and Obesity Affects on Morphine Pharmacokinetics

NCT02732795
View directory record Official record
Conditions
Pediatric Sleep Apnea, Obesity, Morphine Metabolism
Interventions
Morphine pharmacokinetic evaluation
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
5 Years to 12 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 8, 2019 · Synced Sep 9, 2026, 11:38 PM EDT
Withdrawn No phase listed Observational

Outcomes of Partial Versus Complete Tonsillectomy for Obstructive Sleep Disordered Breathing

NCT00519402
View directory record Official record
Conditions
Obstructive Sleep Disordered Breathing
Interventions
tonsillar examination and questionnaire completion
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
5 Years to 28 Years
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 12, 2017 · Synced Sep 9, 2026, 11:38 PM EDT
Enrolling by invitation No phase listed Observational

Computer Models of Airways in Children and Young Adults With Sleep Apnea and Down Syndrome

NCT01902407
View directory record Official record
Conditions
Down Syndrome, Obstructive Sleep Apnea
Interventions
Not listed
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
1 Year to 90 Years
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2028
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 28, 2025 · Synced Sep 9, 2026, 11:38 PM EDT
Withdrawn Phase 4 Interventional

Spironolactone to Improve Apnea and Cardiovascular Markers in Obstructive Sleep Apnea Patients

NCT04205136
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Spironolactone, Placebo
Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 18, 2022 · Synced Sep 9, 2026, 11:38 PM EDT
Completed Not applicable Interventional

Improving Older Adults' Decision Making for OSAT

NCT03138993
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Patient decision aid, General sleep education
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
60 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 25, 2019 · Synced Sep 9, 2026, 11:38 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Use of High-resolution Manometry to Detect Upper Airway Obstruction During Sleep

NCT04139499
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Drug-induced sleep endoscopy (DISE), High-resolution manometry (HRM):
Procedure
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
5 Years to 90 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 12, 2025 · Synced Sep 9, 2026, 11:38 PM EDT
Completed Phase 2 Interventional Results available

Study of Cardiovascular Disease and Obstructive Sleep Apnea

NCT01637623
View directory record Official record
Conditions
Severe Obstructive Sleep Apnea (Apnea Hypopnea Index > 30 Events/Hour), Hypertension
Interventions
Losartan, Allopurinol, Placebo
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
21 Years to 65 Years
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
4
States / cities
Green Bay, Wisconsin • La Crosse, Wisconsin • Madison, Wisconsin + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 13, 2020 · Synced Sep 9, 2026, 11:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cytokine Profiles in Children With Obstructive Sleep Apnea

NCT00456573
View directory record Official record
Conditions
Obstructive Sleep Apnea Syndrome
Interventions
tonsillectomy
Procedure
Lead sponsor
University of Chicago
Other
Eligibility
18 Months to 12 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 5, 2023 · Synced Sep 9, 2026, 11:38 PM EDT
Completed No phase listed Observational

Effect of Nasal CPAP on Cardiopulmonary Exercise Testing in Patients With Overlap Syndrome

NCT01033266
View directory record Official record
Conditions
Obstructive Sleep Apnea, Chronic Obstructive Pulmonary Disease
Interventions
CPET
Diagnostic Test
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
2
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 13, 2020 · Synced Sep 9, 2026, 11:38 PM EDT
Completed No phase listed Interventional Results available

The Evaluation of a Full Face Mask Seal for the Treatment of Obstructive Sleep Apnea

NCT03230877
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Toffee full face mask with 'Improved Seal', Toffee full face mask with 'Normal Seal'
Device
Lead sponsor
Fisher and Paykel Healthcare
Industry
Eligibility
22 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Sep 7, 2022 · Synced Sep 9, 2026, 11:38 PM EDT
Completed Not applicable Interventional Results available

Trial on Oral Appliance Design for Improving Upper Airway Function and Sleep Quality

NCT03219034
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
oral appliance - A ; washout; oral appliance B, oral appliance - B; washout; oral appliance A
Device
Lead sponsor
Texas A&M University
Other
Eligibility
18 Years and older
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 9, 2022 · Synced Sep 9, 2026, 11:38 PM EDT
Not yet recruiting Not applicable Interventional

Enhancing PAP Adherence Among Spanish-speaking Hispanic Adults With OSA

NCT05618444
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Automated Management (AM)
Behavioral
Lead sponsor
Geisinger Clinic
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
4
States / cities
Fontana, California • Kansas City, Kansas • Danville, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Sep 9, 2026, 11:38 PM EDT
Not yet recruiting No phase listed Observational

Application of the Patient-reported Longitudinal Assessment Tool for OSA (PLATO) Questionnaire in Oral Appliance Therapy for Obstructive Sleep Apnea

NCT07789834
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA), Oral Applliance Therapy
Interventions
The study will assess the feasibility of incorporating the PLATO questionnaire into a dental sleep practice. The PLATO questionnaire was developed as a patient reported outcome measure
Other
Lead sponsor
Nevada Dental Sleep
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Henderson, Nevada
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Sep 9, 2026, 11:38 PM EDT
Recruiting Phase 1Phase 2 Interventional

Atomoxetine and DAW2022 on OSA Severity

NCT05350215
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Placebo oral capsule, Atomoxetine Oral Capsule [Strattera]
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years to 70 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Sep 9, 2026, 11:38 PM EDT
Recruiting Not applicable Interventional

The REPOSE (Reach for Equity in Pediatric Sleep Evaluation) Navigation Intervention

NCT06828835
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Reach for Equity in Pediatric Obstructive Sleep Evaluation (REPOSE), Usual Care
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
2 Years to 12 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Sep 9, 2026, 11:38 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

TipTraQ Home Sleep Test Validation Study, Duke

NCT06351878
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Not listed
Lead sponsor
PranaQ Pte. Ltd.
Industry
Eligibility
20 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 21, 2024 · Synced Sep 9, 2026, 11:38 PM EDT
Withdrawn Not applicable Interventional

Whole Body Vibration for OSA

NCT03377621
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Whole Body Vibration
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
21 Years to 60 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 16, 2019 · Synced Sep 9, 2026, 11:38 PM EDT