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ClinicalTrials.gov public records Last synced Oct 21, 2026, 6:21 PM EDT

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Showing 457–480 of 1,077 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Apnea Clear all
Completed Phase 1 Interventional

Evaluate Sunosi® PK in Breast Milk and Plasma of Healthy Postpartum Women Following Single Dose Oral Administration

NCT05008341
View directory record Official record
Conditions
Narcolepsy, Obstructive Sleep Apnea, Excessive Daytime Somnolence, Excessive Sleepiness, Postpartum
Interventions
Solriamfetol 150 mg Oral Tablet
Drug
Lead sponsor
Axsome Therapeutics, Inc.
Industry
Eligibility
18 Years to 50 Years · Female only
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 14, 2023 · Synced Oct 21, 2026, 6:21 PM EDT
Withdrawn Not applicable Interventional

Non-Inferiority Trial of Acute HFT Versus nCPAP

NCT01860560
View directory record Official record
Conditions
Mild-Moderate Obstructive Sleep Disordered Breathing
Interventions
High-Flow Therapy, Continuous Positive Airway Pressure
Device
Lead sponsor
Vapotherm, Inc.
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Glen Burnie, Maryland
Source: ClinicalTrials.gov public record
Updated May 3, 2023 · Synced Oct 21, 2026, 6:21 PM EDT
Completed Not applicable Interventional

Sleep Apnea Video Education for CPAP (SAVE-CPAP)

NCT02553694
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Enhanced education, Usual education, Usual follow up, Enhanced follow up
Other
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
212 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 3, 2017 · Synced Oct 21, 2026, 6:21 PM EDT
Completed Phase 3 Interventional Results available

PMP-300E (Smart Watch): Portable Monitoring Device Study

NCT01364740
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
PMP-300E, In-lab PSG
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
2
States / cities
Redwood City, California • Stanford, California
Source: ClinicalTrials.gov public record
Updated Jan 27, 2017 · Synced Oct 21, 2026, 6:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Pilot Study of CPAP Adherence Promotion by Peer Buddies With Sleep Apnea

NCT01164683
View directory record Official record
Conditions
Sleep Apnea
Interventions
Peer-driven intervention, Usual Care
Behavioral · Other
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
21 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Apr 7, 2015 · Synced Oct 21, 2026, 6:21 PM EDT
Completed Phase 3 Interventional

Effect of Heated Humidity With Thermosmart™ Compared to an Intranasal Steroid in Improving Compliance and Nasal Symptoms in Patients Using Continuous Positive Airway Pressure

NCT00665977
View directory record Official record
Conditions
Obstructive Sleep Apnea, Nasal Congestion, Sinus Congestion
Interventions
Thermosmart & placebo, Placebo Device & Nasacort, Placebo Arm
Drug · Device
Lead sponsor
Clayton Sleep Insititute
Industry
Eligibility
16 Years to 65 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 7, 2010 · Synced Oct 21, 2026, 6:21 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Supplemental Oxygen and Oxygen Desaturations in Colonoscopies

NCT07515755
View directory record Official record
Conditions
Oxygen Desaturation, Apnea (Central and Obstructive), Airway Obstruction
Interventions
Breath-synchronized oxygen, CPAP, Control
Device
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
280 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
South Jordan, Utah
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Oct 21, 2026, 6:21 PM EDT
Completed Not applicable Interventional

Workflow Validation of an In-home Auto-titrating Mandibular Positioner

NCT02933112
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Auto-titrating mandibular positioner test
Device
Lead sponsor
Zephyr Sleep Technologies
Industry
Eligibility
18 Years and older
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Bellevue, Washington
Source: ClinicalTrials.gov public record
Updated Oct 17, 2018 · Synced Oct 21, 2026, 6:21 PM EDT
Recruiting No phase listed Observational

A Prospective Study to Evaluate the WP in Comparison to PSG in Patients Suspected of Sleep Disorders

NCT06093633
View directory record Official record
Conditions
Sleep Disorder
Interventions
Not listed
Lead sponsor
Itamar-Medical, Israel
Industry
Eligibility
12 Years to 99 Years
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
Baltimore, Maryland • Towson, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 22, 2025 · Synced Oct 21, 2026, 6:21 PM EDT
Completed Not applicable Interventional Results available

Impact of Exenatide on Sleep in Type 2 Diabetes

NCT01136798
View directory record Official record
Conditions
Type 2 Diabetes, Sleep Disordered Breathing
Interventions
Exenatide, Placebo
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
2
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 12, 2018 · Synced Oct 21, 2026, 6:21 PM EDT
Active, not recruiting Not applicable Interventional

Breathing Training for Improving Cardiovascular Health in Older Adults With Sleep Apnea

NCT04932447
View directory record Official record
Conditions
Obstructive Sleep Apnea, Hypertension
Interventions
Inspiratory Muscle Strength Training
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
50 Years and older
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Oct 8, 2025 · Synced Oct 21, 2026, 6:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Ketogenic Diet for Obesity Hypoventilation Syndrome

NCT04108819
View directory record Official record
Conditions
Obesity Hypoventilation Syndrome, Ketogenic Dieting, Hypercapnic Respiratory Failure
Interventions
Ketogenic Diet
Dietary Supplement
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2022 · Synced Oct 21, 2026, 6:21 PM EDT
Completed No phase listed Observational

Effects of CPAP Therapy on PTSD Symptoms

NCT02019914
View directory record Official record
Conditions
PTSD, Sleep, Obstructive Sleep Apnea, Quality of Life
Interventions
Not listed
Lead sponsor
Veterans Medical Research Foundation
Other
Eligibility
18 Years and older
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Dec 14, 2015 · Synced Oct 21, 2026, 6:21 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Corneal Sensitivity in Patients With Sleep Apnea Syndrome

NCT02265133
View directory record Official record
Conditions
Sleep Apnea
Interventions
Not listed
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 90 Years
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2024
U.S. locations
2
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 21, 2024 · Synced Oct 21, 2026, 6:21 PM EDT
Completed Phase 2 Interventional Results available

The Sleep, Liver Evaluation and Effective Pressure Study

NCT01482065
View directory record Official record
Conditions
Non Alcoholic Fatty Liver Disease, Obstructive Sleep Apnea
Interventions
CPAP (ResMed S9 autoset CPAP)
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 4, 2017 · Synced Oct 21, 2026, 6:21 PM EDT
Completed Not applicable Interventional Results available

Prospective Use of Awake Endoscopy for Inspire Activation

NCT03990298
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Awake endoscopy
Diagnostic Test
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 4, 2021 · Synced Oct 21, 2026, 6:21 PM EDT
Completed No phase listed Observational

Sleep-disordered Breathing in Infants With Myelomeningocele

NCT04251806
View directory record Official record
Conditions
Sleep-disordered Breathing, Myelomeningocele
Interventions
neonatal polysomnography, 2-year Bayley Exam, 2-year polysomnography
Diagnostic Test
Lead sponsor
University of Michigan
Other
Eligibility
Up to 2 Years
Enrollment
173 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
9
States / cities
Birmingham, Alabama • Aurora, Colorado • Ann Arbor, Michigan + 6 more
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Oct 21, 2026, 6:21 PM EDT
Completed Not applicable Interventional

Treating Sleep Apnea Induced Hypoxemia With Oxygen in Acute Stroke Patients

NCT03300063
View directory record Official record
Conditions
Stroke, Acute
Interventions
Low flow nocturnal oxygen
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 25, 2021 · Synced Oct 21, 2026, 6:21 PM EDT
Completed Phase 2 Interventional

Do Endotypes Predict Response and Sequelae in OSA Patients

NCT04875364
View directory record Official record
Conditions
Obstructive Sleep Apnea, Sleep Apnea, Sleep Apnea, Obstructive, Sleep, Sleep Disorder
Interventions
Eszopiclone, Supplemental Oxygen, Continuous Positive Airway Pressure (CPAP)
Drug · Other · Device
Lead sponsor
University of California, San Diego
Other
Eligibility
21 Years to 65 Years
Enrollment
233 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jun 18, 2026 · Synced Oct 21, 2026, 6:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Determinants of Age Related Breathing Instability During Non-Rapid-Eye-Movement (NREM) Sleep

NCT00732199
View directory record Official record
Conditions
Sleep Apnea, Age
Interventions
1) hyperventilation via noninvasive positive pressure ventilation 2) multiple trials of episodic hypoxia
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 89 Years
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2015
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 28, 2017 · Synced Oct 21, 2026, 6:21 PM EDT
Recruiting Not applicable Interventional

OurSleepKit To Support CPAP Adherence

NCT06621511
View directory record Official record
Conditions
Obstructive Sleep Apnea, CPAP Treatment, Treatment Adherence
Interventions
OurSleepKit
Behavioral
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
2
States / cities
Boston, Massachusetts • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Oct 21, 2026, 6:21 PM EDT
Completed Not applicable Interventional Results available

Mild Cognitive Impairment and Obstructive Sleep Apnea

NCT01482351
View directory record Official record
Conditions
Obstructive Sleep Apnea, Mild Cognitive Impairment
Interventions
CPAP adherence intervention, Attention control intervention
Behavioral
Lead sponsor
George Mason University
Other
Eligibility
55 Years to 89 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
3
States / cities
Abington, Pennsylvania • Philadelphia, Pennsylvania • Fairfax, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 6, 2019 · Synced Oct 21, 2026, 6:21 PM EDT
Recruiting No phase listed Observational

Predicting Outcomes in Hypoglossal Nerve Stimulation Therapy With Stimulated Upper Airway Mechanics

NCT05429983
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Not listed
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Timeline
2022 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 24, 2025 · Synced Oct 21, 2026, 6:21 PM EDT
Completed Not applicable Interventional Results available

Respicardia, Inc. Pivotal Trial of the remedē System

NCT01816776
View directory record Official record
Conditions
Sleep Apnea, Central, Sleep Disordered Breathing, Heart Failure
Interventions
Treatment Group (transvenous stimulation of the phrenic nerve), Control Group (Optimal Medical Therapy)
Device
Lead sponsor
Respicardia, Inc.
Industry
Eligibility
18 Years and older
Enrollment
151 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
23
States / cities
Los Angeles, California • Jacksonville, Florida • Downers Grove, Illinois + 19 more
Source: ClinicalTrials.gov public record
Updated Jun 29, 2018 · Synced Oct 21, 2026, 6:21 PM EDT