Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Oct 23, 2026, 1:20 PM EDT

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Showing 841–864 of 1,077 matching trials from the live ClinicalTrials.gov search.
Conditions
Apnea of Prematurity
Interventions
Caffeine, Sterile Water Placebo
Drug · Other
Lead sponsor
University of California, Irvine
Other
Eligibility
1 Week to 40 Weeks
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Orange, California
Conditions
Intubation
Interventions
Apneic oxygenation, Pre-oxgenation with NRB, NIPPV, BVM
Other
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Murray, Utah
Conditions
Obstructive Sleep Apnea, Heart Failure; With Decompensation
Interventions
Not listed
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 80 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
2
States / cities
San Diego, California
Conditions
Sleep Apnea, Obstructive, Total Knee Arthroplasty, Total Hip Arthroplasty
Interventions
Evaluation by Sleep Medicine Specialists
Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Miami, Florida
Completed Not applicable Interventional Results available

TheraPAP Equivalence Crossover Study

NCT06238362
Conditions
Obstructive Sleep Apnea
Interventions
TPAP, CPAP
Other · Device
Lead sponsor
SleepRes Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Clarksville, Tennessee
Completed Not applicable Interventional Results available

Mandibular Advancement Device and Changes in Nocturia

NCT05562388
Conditions
Obstructive Sleep Apnea, Nocturia, OSA
Interventions
Somnodent Classic
Device
Lead sponsor
Isabel Moreno Hay
Other
Eligibility
18 Years to 80 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Lexington, Kentucky
Conditions
Sleep Apnea, Obstructive
Interventions
CPAP + Peer Support, CPAP + Individual Education
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Completed No phase listed Observational Accepts healthy volunteers

Fat Biology, Sleep Disorders, and Cardiovascular Disease

NCT01229501
Conditions
Sleep Disordered Breathing, Cardiovascular Disease
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2016
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Sleep Apnea, Adverse Event
Interventions
Questionaire
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
350 participants
Timeline
2018 – 2021
U.S. locations
1
States / cities
Weston, Florida
Conditions
Snoring, Obstructive Sleep Apnea
Interventions
Smart pillow
Device
Lead sponsor
Indiana University
Other
Eligibility
50 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Indianapolis, Indiana
Conditions
Sleep Apnea
Interventions
Behavioral strategy program X plus Y, Behavioral strategy program X
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years and older
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
2
States / cities
West Los Angeles, California • Detroit, Michigan
Conditions
Sleep Disorder; Breathing-Related, Pain, Sleep Apnea, Obstructive Sleep Apnea, Sleep, Sleep Disorder, Chronic Pain, Opioid Use
Interventions
Positive Airway Pressure (PAP)
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
San Diego, California
Conditions
Obstructive Sleep Apnea
Interventions
Device: Trial nasal mask (F&P)
Device
Lead sponsor
Fisher and Paykel Healthcare
Industry
Eligibility
22 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Obstructive Sleep Apnea
Interventions
Upper airway stimulation (Inspire Medical Systems, Inc.)
Device
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Obstructive Sleep Apnea of Adult
Interventions
Cryosa Procedure
Device
Lead sponsor
Cryosa, Inc.
Industry
Eligibility
22 Years to 70 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
9
States / cities
Aurora, Colorado • Miami, Florida • Chicago, Illinois + 6 more
Conditions
Obstructive Sleep Apnea, Snoring
Interventions
Tongue Advancement Retainer Device
Device
Lead sponsor
Sleepy, Inc
Industry
Eligibility
18 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
2
States / cities
San Diego, California • Visalia, California
Recruiting No phase listed Observational Accepts healthy volunteers

Obstructive Sleep Apnea Among Somali-Americans

NCT04124848
Conditions
Obstructive Sleep Apnea
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2031
U.S. locations
1
States / cities
Rochester, Minnesota
Completed Not applicable Interventional Accepts healthy volunteers Results available

Mechanisms of Upper Airway Obstruction

NCT04322097
Conditions
Obstructive Sleep Apnea
Interventions
Hypoglossal Nerve Stimulation
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
22 Years and older
Enrollment
133 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Completed Phase 4 Interventional Results available

Oxygen Versus PAP for Sleep Apnea in Heart Failure

NCT01807897
Conditions
Heart Failure, Sleep Apnea Syndromes
Interventions
Continuous positive airway pressure, Nocturnal supplemental oxygen, Healthy Lifestyle and Sleep Education
Device · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
2
States / cities
West Haven, Connecticut • Boston, Massachusetts
Conditions
Obstructive Sleep Apnea (OSA), Down Syndrome
Interventions
ato-oxy, Oxygen
Drug
Lead sponsor
University of Arizona
Other
Eligibility
6 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
5
States / cities
Tucson, Arizona • San Diego, California • Miami, Florida + 2 more
Enrolling by invitation Not applicable Interventional

Myofunctional Therapy for Obstructive Sleep Apnea

NCT07301125
Conditions
Obstructive Sleep Apnea
Interventions
Myofunctional Therapy
Procedure
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Sleep-Disordered Breathing, Obstructive Sleep Apnea, Central Sleep Apnea, Chronic Pain, Opioid Use
Interventions
Acetazolamide, Placebo
Drug · Other
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
San Diego, California
Completed Phase 1Phase 2 Interventional Results available

DAW1033D in Obstructive Sleep Apnea

NCT03383887
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
Placebo oral capsule, DAW1033D oral capsule
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years to 65 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Sleep Apnea, Obstructive
Interventions
Oxytocin Intranasal Spray, Placebo Intranasal Spray
Drug
Lead sponsor
George Washington University
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Washington D.C., District of Columbia