Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Oct 24, 2026, 5:30 AM EDT

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Showing 937–960 of 1,077 matching trials from the live ClinicalTrials.gov search.
Conditions
Obesity, Obstructive Sleep Apnea
Interventions
ExSpiron Respiratory Volume Monitor (RVM, ExSpiron™, Respiratory Motion, Inc.; Waltham, MA
Device
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Obstructive Sleep Apnea
Interventions
RXiBreeze PAP System, Model RXiBreeze 20A
Device
Lead sponsor
Resvent Holding USA LTD
Industry
Eligibility
22 Years and older
Enrollment
146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
9
States / cities
Burlingame, California • Chula Vista, California • Mountain View, California + 6 more
Conditions
Sleep Apnea
Interventions
Induced central apneas
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Sleep Apnea
Interventions
Telemonitoring, Peer Based, CPAP Education, Usual Care
Behavioral
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Obstructive Sleep Apnea
Interventions
BiPap auto with Fi Flex, Standard CPAP
Device
Lead sponsor
Clayton Sleep Insititute
Industry
Eligibility
21 Years to 75 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Obstructive Sleep Apnea
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
20 Years to 70 Years
Enrollment
60 participants
Timeline
2024 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Apnea of Prematurity
Interventions
Stochastic Resonance Mattress
Device
Lead sponsor
Wyss Institute at Harvard University
Other
Eligibility
Not listed
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Obstructive Sleep Apnea, Coronary Heart Disease
Interventions
CPAP, HLSE
Device · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Obstructive Sleep Apnea
Interventions
Hypoglossal Nerve Stimulation (HGNS) System (Apnex Medical )
Device
Lead sponsor
Apnex Medical, Inc.
Industry
Eligibility
21 Years to 80 Years
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
12
States / cities
Lenexa, Kansas • Topeka, Kansas • Louisville, Kentucky + 9 more
Conditions
Obstructive Sleep Apnea
Interventions
Melatonin, Placebo
Dietary Supplement · Other
Lead sponsor
Naomi Deacon
Other
Eligibility
30 Years to 60 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
San Diego, California
Withdrawn Not applicable Interventional Accepts healthy volunteers

Sparkle Respiratory Effort Validation

NCT04630639
Conditions
Sleep Apnea, Obstructive, Sleep Apnea, Central
Interventions
Sparkle
Device
Lead sponsor
Philips Clinical & Medical Affairs Global
Industry
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Hypercapnic Respiratory Failure, Chronic Obstructive Pulmonary Disease, Obesity Hypoventilation Syndrome, Sleep Disordered Breathing, Neuromuscular Diseases
Interventions
Vivify, EMS
Other
Lead sponsor
Albert Einstein Healthcare Network
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Obstructive Sleep Disorder, Obstructive Sleep Apnea, Tonsillar Hypertrophy
Interventions
Micropolysaccharide Hemospheres (Arista), Electrocautery (Monopolar suction cautery)
Device
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
5 Years to 18 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparison of Two Techniques of Combination Therapy for Treatment of Obstructive Sleep Apnea (OSA)

NCT04029311
Conditions
Treatment for Obstructive Sleep Apnea
Interventions
Nuance Pro, autoPAP, TAP PAP
Device
Lead sponsor
Joseph Adame
Individual
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Edinburg, Texas
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Treating Sleep Apnea on Cognition in Patients With Dementia

NCT00477828
Conditions
Dementia, Sleep Apnea
Interventions
Continuous positive airway pressure
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
50 Years to 85 Years
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2006
U.S. locations
1
States / cities
San Diego, California
Conditions
Sleep Apnea, Sleep Disturbance
Interventions
Couples-based treatment- Patient, Couples-based treatment- Partner, Information control- Patient, Information control- Partner
Behavioral · Other
Lead sponsor
University of Utah
Other
Eligibility
35 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Tuscon, Arizona • Salt Lake City, Utah
Active, not recruiting No phase listed Observational Accepts healthy volunteers

GARM II: A Study on the Genetics of Age-related Maculopathy

NCT01115387
Conditions
Age-related Macular Degeneration, Age-related Maculopathy
Interventions
Observational-1, Observational-2
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
49 Years and older
Enrollment
603 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2027
U.S. locations
2
States / cities
Los Angeles, California • Pittsburgh, Pennsylvania
Completed Not applicable Interventional Results available

Impact of Exenatide on Sleep in Type 2 Diabetes

NCT01136798
Conditions
Type 2 Diabetes, Sleep Disordered Breathing
Interventions
Exenatide, Placebo
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
2
States / cities
Chicago, Illinois
Completed Not applicable Interventional Results available

Servo-Ventilation In-lab PSG Evaluation

NCT02808338
Conditions
Sleep Apnea Syndromes
Interventions
Philips BiPAP AutoSV Advanced System One, Modified Philips BiPAP ASV, ResMed S7 VPAP Adapt, ResMed S9 VPAP Adapt
Device
Lead sponsor
Philips Respironics
Industry
Eligibility
21 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Tucson, Arizona
Conditions
Obstructive Sleep Apnea
Interventions
Varnum mouthpiece
Device
Lead sponsor
David Andrew Wellman
Other
Eligibility
21 Years to 70 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Phase 3 Interventional Accepts healthy volunteers

Fat Gain and Cardiovascular Disease Mechanisms

NCT00589498
Conditions
Hypertension, Sleep Apnea Syndromes, Obesity
Interventions
1000 extra calories
Dietary Supplement
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 40 Years
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2012
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Afib, Sleep Apnea Syndrome, Obstructive, CPAP
Interventions
CPAP
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Cleveland, Ohio • Seattle, Washington
Conditions
PTSD, Sleep, Obstructive Sleep Apnea, Quality of Life
Interventions
Not listed
Lead sponsor
Veterans Medical Research Foundation
Other
Eligibility
18 Years and older
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
San Diego, California
Conditions
Obstructive Sleep Apnea, Cognitive Change
Interventions
CATNAP MI
Behavioral
Lead sponsor
Washington State University
Other
Eligibility
40 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Eagle Butte, South Dakota