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ClinicalTrials.gov public records Last synced Oct 24, 2026, 8:10 AM EDT

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Showing 985–1008 of 1,077 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Apnea Clear all
Completed Not applicable Interventional Results available

DeVilbiss AutoAdjust With SmartFlex Comparative Study

NCT01203956
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
SmartFlex, Standard
Device
Lead sponsor
DeVilbiss Healthcare LLC
Industry
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
2
States / cities
Dallas, Texas • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Apr 28, 2015 · Synced Oct 24, 2026, 8:10 AM EDT
Completed Phase 1Phase 2 Interventional

Combination Pharmacological Interventions for Multiple Mechanisms of Obstructive Sleep Apnea

NCT03892772
View directory record Official record
Conditions
Sleep Apnea
Interventions
SAS0421a, SAS0421b, SAS0421c, placebo
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 79 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 2, 2022 · Synced Oct 24, 2026, 8:10 AM EDT
Completed Not applicable Interventional

Impact of Automated Education and Follow-up Mechanisms on Patient Engagement

NCT02279901
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Telemedicine Education, IVR
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
1,873 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Fontana, California
Source: ClinicalTrials.gov public record
Updated Mar 6, 2017 · Synced Oct 24, 2026, 8:10 AM EDT
Recruiting Not applicable Interventional

Treatment of Obstructive Sleep Apnea With Personalized Surgery in Children With Down Syndrome (TOPS-DS)

NCT05508971
View directory record Official record
Conditions
Obstructive Sleep Apnea, Down Syndrome
Interventions
DISE-Directed Surgery, Adenotonsillectomy
Procedure
Lead sponsor
Oregon Health and Science University
Other
Eligibility
2 Years to 17 Years
Enrollment
304 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
7
States / cities
Aurora, Colorado • Ann Arbor, Michigan • Cincinnati, Ohio + 4 more
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 24, 2026, 8:10 AM EDT
Completed Phase 2 Interventional

Heart Biomarker Evaluation in Apnea Treatment

NCT01086800
View directory record Official record
Conditions
Cardiovascular Disease, Obstructive Sleep Apnea, Coronary Artery Disease
Interventions
Healthy Lifestyles and Sleep Education plus PAP, Healthy Lifestyles and Sleep Education plus Supplemental Oxygen, Healthy Lifestyles and Sleep Education
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
45 Years to 75 Years
Enrollment
318 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
4
States / cities
Baltimore, Maryland • Boston, Massachusetts • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 25, 2013 · Synced Oct 24, 2026, 8:10 AM EDT
Completed Not applicable Interventional Results available

Positive Airway Pressure Program

NCT02331992
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Adherence program
Behavioral
Lead sponsor
Fisher and Paykel Healthcare
Industry
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
3
States / cities
Huntsville, Alabama • Belleville, Illinois • Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 29, 2018 · Synced Oct 24, 2026, 8:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sleep Apnea and Obesity Affects on Morphine Pharmacokinetics

NCT02732795
View directory record Official record
Conditions
Pediatric Sleep Apnea, Obesity, Morphine Metabolism
Interventions
Morphine pharmacokinetic evaluation
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
5 Years to 12 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 9, 2019 · Synced Oct 24, 2026, 8:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sleep Apnea and Vascular Function

NCT01717339
View directory record Official record
Conditions
OSA
Interventions
Sleep Study
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 13, 2017 · Synced Oct 24, 2026, 8:10 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

CPAP Population Management

NCT04559737
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
Case Management
Other
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Fontana, California
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Oct 24, 2026, 8:10 AM EDT
Completed Not applicable Interventional

Comparison of Dreem to Clinical PSG for Sleep Monitoring in Apnea Patients

NCT03657329
View directory record Official record
Conditions
Sleep, Sleep Apnea
Interventions
Dreem
Diagnostic Test
Lead sponsor
Dreem
Industry
Eligibility
18 Years to 70 Years
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Nov 28, 2018 · Synced Oct 24, 2026, 8:10 AM EDT
Terminated Not applicable Interventional Results available

Adherence to ASV Therapy in Heart Failure With Preserved Ejection Fraction Feasibility Study

NCT03195660
View directory record Official record
Conditions
Heart Failure With Normal Ejection Fraction, Sleep Apnea
Interventions
ASV Therapy
Device
Lead sponsor
ResMed
Industry
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
3
States / cities
San Diego, California • Philadelphia, Pennsylvania • Falls Church, Virginia
Source: ClinicalTrials.gov public record
Updated May 14, 2021 · Synced Oct 24, 2026, 8:10 AM EDT
Active, not recruiting Not applicable Interventional

Therapist-Directed VS Online Therapy for Insomnia Co-Occuring With Sleep Apnea

NCT03109210
View directory record Official record
Conditions
Insomnia, Primary, Sleep Apnea, Obstructive
Interventions
Online Cognitive Behavioral Therapy (OCBT), Therapist-directed Cognitive Behavioral Therapy (TCBT)
Behavioral
Lead sponsor
National Jewish Health
Other
Eligibility
21 Years and older
Enrollment
384 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2026
U.S. locations
2
States / cities
Palo Alto, California • Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 21, 2025 · Synced Oct 24, 2026, 8:10 AM EDT
Terminated Not applicable Interventional Results available

Diabetes-Obstructive Sleep Apnea Treatment Trial

NCT01901055
View directory record Official record
Conditions
Type 2 Diabetes, Obstructive Sleep Apnea
Interventions
CPAP, Sham-CPAP, Diabetes Education
Device · Behavioral
Lead sponsor
Eileen R. Chasens
Other
Eligibility
18 Years and older
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
4
States / cities
Detroit, Michigan • Pittsburgh, Pennsylvania • Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Aug 16, 2021 · Synced Oct 24, 2026, 8:10 AM EDT
Recruiting No phase listed Observational

Inspire UAS High Apnea Hypopnea Index (AHI)/High Body Mass Index (BMI) Post-Approval Study

NCT07113288
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
Inspire® UAS System
Device
Lead sponsor
Inspire Medical Systems, Inc.
Industry
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2032
U.S. locations
5
States / cities
Colorado Springs, Colorado • Bradenton, Florida • Chicago, Illinois + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 24, 2026, 8:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Advancing Understanding of Transportation Options

NCT04141891
View directory record Official record
Conditions
Diabetic Retinopathy, Macular Degeneration, Glaucoma, Retinitis Pigmentosa, Vision Disorders, Acute Coronary Syndrome, Implantable Defibrillator User, Congestive Heart Failure, Hypertrophic Obstructive Cardiomyopathy, Orthostatic Hypotension, Syncope, Presyncope, Narcolepsy, Dementia, Multiple Sclerosis, Parkinson Disease, Brain Injuries, Spinal Cord Injuries, Stroke, Vertigo, Dizziness, Seizures, Substance Use, Insulin Dependent Diabetes Mellitus, Arthritis, Foot--Abnormalities, Chronic Obstructive Pulmonary Disease, Obstructive Sleep Apnea, End Stage Renal Disease, Sleep Apnea, Insomnia, Restless Legs Syndrome
Interventions
Driving Decision Aid, Older Drivers Website
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
529 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
3
States / cities
La Jolla, California • Aurora, Colorado • Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 21, 2025 · Synced Oct 24, 2026, 8:10 AM EDT
Recruiting Not applicable Interventional

Self-Supporting Nasopharyngeal Airway (ssNPA) Treating Upper Airway Obstruction in Hypotonia

NCT05527652
View directory record Official record
Conditions
Obstructive Sleep Apnea, Hypertonia, Muscle, Nasal Airway Obstruction, Tolerance, Trisomy 21, Down Syndrome
Interventions
Self-Supporting Nasopharyngeal Airway (ssNPA)
Device
Lead sponsor
University of Michigan
Other
Eligibility
3 Years to 21 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 24, 2026, 8:10 AM EDT
Completed Phase 3 Interventional Results available

Montelukast and Inhaled Nasal Steroid Tx in Adult Obstructive Sleep Apnea (OSA)

NCT01089647
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
budesonide and montelukast, Placebo
Drug
Lead sponsor
Romaker & Associates
Other
Eligibility
18 Years to 100 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
2
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 3, 2018 · Synced Oct 24, 2026, 8:10 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Early Dental Risk Screening for Pediatric Sleep-Disordered Breathing

NCT07581938
View directory record Official record
Conditions
Early Risk Screening for Sleep Disordered Breathing in a Dental Setting, Sleep Disordered Breathing (SDB), Obstructive Sleep Apnea (OSA)
Interventions
SleepImage Ring
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
8 Years to 13 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 23, 2026 · Synced Oct 24, 2026, 8:10 AM EDT
Not listed Not applicable Interventional

Adaptive Servo-Ventilation In Acute Heart Failure Patients Protecting the Heart and Kidneys

NCT02796638
View directory record Official record
Conditions
Heart Failure, Sleep Apnea, Obstructive
Interventions
Adaptive Servo-Ventilation
Device
Lead sponsor
Veterans Medical Research Foundation
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jan 27, 2020 · Synced Oct 24, 2026, 8:10 AM EDT
Completed Not applicable Interventional Results available

Novel by Upper Airway Respiratory Muscle Training to Treat OSA in Chronic SCI

NCT03664765
View directory record Official record
Conditions
OSA, SCI/D, Upper Airway Exercise
Interventions
UA and RMT, Sham exercise
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 89 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 12, 2024 · Synced Oct 24, 2026, 8:10 AM EDT
Completed No phase listed Observational

Computer Models of Airways in Children and Young Adults With Sleep Apnea and Down Syndrome

NCT01902407
View directory record Official record
Conditions
Down Syndrome, Obstructive Sleep Apnea
Interventions
Not listed
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
1 Year to 90 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2026
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 24, 2026, 8:10 AM EDT
Completed Not applicable Interventional Results available

Prospective Use of Awake Endoscopy for Inspire Activation

NCT03990298
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Awake endoscopy
Diagnostic Test
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 4, 2021 · Synced Oct 24, 2026, 8:10 AM EDT
Completed No phase listed Observational

The Effect of Standardizing the Definition of a Clinically Significant Cardiopulmonary Event on Length of Stay

NCT03414671
View directory record Official record
Conditions
Apnea of Prematurity
Interventions
Not listed
Lead sponsor
Pediatrix
Other
Eligibility
23 Weeks to 29 Weeks
Enrollment
160 participants
Timeline
2018 – 2021
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 4, 2021 · Synced Oct 24, 2026, 8:10 AM EDT