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ClinicalTrials.gov public records Last synced Oct 24, 2026, 2:47 PM EDT

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Showing 1057–1077 of 1,077 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Apnea Clear all
Withdrawn No phase listed Observational Accepts healthy volunteers

Effect of Interscalene Block on Obstructive Sleep Apnea in Shoulder Surgery Patients

NCT02034370
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Lung-function spirometry test, Overnight sleep test
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
2
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 30, 2016 · Synced Oct 24, 2026, 2:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Hemodynamics Response to Upper Airway Obstruction in Marfan Syndrome

NCT03985657
View directory record Official record
Conditions
Sleep-disordered Breathing, Snoring
Interventions
CPAP
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 28, 2020 · Synced Oct 24, 2026, 2:47 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Assessment of PPG & PAT to Detect Upper Airway Obstruction in Patients With Obstructive Sleep Apnea

NCT01831583
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Measurement of PPG waveforms, Measurement of Pulse Arrival Time (PAT)
Device
Lead sponsor
Sotera Wireless, Inc.
Industry
Eligibility
21 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Escondido, California
Source: ClinicalTrials.gov public record
Updated Apr 15, 2013 · Synced Oct 24, 2026, 2:47 PM EDT
Completed Not applicable Interventional Results available

Atrial Fibrillation Recurrence in Sleep Apnea

NCT00263757
View directory record Official record
Conditions
Sleep Apnea, Atrial Fibrillation
Interventions
Adaptive Servo-Ventilation, Usual Care
Device · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 1, 2014 · Synced Oct 24, 2026, 2:47 PM EDT
Completed Not applicable Interventional Results available

Effects of Continuous Positive Airway Pressure (CPAP) on Glucose Metabolism

NCT01503164
View directory record Official record
Conditions
Obstructive Sleep Apnea, Sleep Apnea, Sleep-disordered Breathing
Interventions
Positive Pressure Therapy (PAP), LifeStyle Counseling
Device · Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years to 75 Years
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 19, 2017 · Synced Oct 24, 2026, 2:47 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Serotonin and the Upper Airway in Obstructive Sleep Apnea

NCT00100464
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Paroxetine, 5HTP
Drug
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
16 Years to 60 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2003
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 17, 2013 · Synced Oct 24, 2026, 2:47 PM EDT
Completed Phase 1Phase 2 Interventional

Testing of the Apnea Prevention Device

NCT00875134
View directory record Official record
Conditions
Respiratory Depression, Elective Surgery
Interventions
Verbal prompt, Skin Stimulus
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
21 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jun 18, 2019 · Synced Oct 24, 2026, 2:47 PM EDT
Not yet recruiting Not applicable Interventional

KPAP Adherence Crossover Study

NCT06413134
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
KPAP, APAP
Device
Lead sponsor
SleepRes Inc.
Industry
Eligibility
20 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Murfreesboro, Tennessee
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 24, 2026, 2:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Ketogenic Diet for Obesity Hypoventilation Syndrome

NCT04108819
View directory record Official record
Conditions
Obesity Hypoventilation Syndrome, Ketogenic Dieting, Hypercapnic Respiratory Failure
Interventions
Ketogenic Diet
Dietary Supplement
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2022 · Synced Oct 24, 2026, 2:47 PM EDT
Terminated Phase 3 Interventional

Modafinil to Treat Fatigue in Post-Polio Syndrome

NCT00067496
View directory record Official record
Conditions
Postpoliomyelitis Syndrome
Interventions
Modafinil
Drug
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2006
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 27, 2008 · Synced Oct 24, 2026, 2:47 PM EDT
Not listed No phase listed Observational

Identification of Desaturation Episodes by Means of Continuous Measurement of Oxygen Saturation During Hemodialysis

NCT02987179
View directory record Official record
Conditions
ESRD, Sleep Apnea, Oxygen Deficiency
Interventions
Observational
Other
Lead sponsor
Renal Research Institute
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 8, 2016 · Synced Oct 24, 2026, 2:47 PM EDT
Completed Phase 4 Interventional Results available

MRI and Neurodevelopment in Preterm Infants Following Administration of High-Dose Caffeine

NCT00809055
View directory record Official record
Conditions
Apnea of Prematurity, Intraventricular Hemorrhage, Brain Injury
Interventions
Caffeine citrate
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
24 Weeks to 30 Weeks
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 24, 2016 · Synced Oct 24, 2026, 2:47 PM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Ketamine and Propofol Combination Versus Propofol for Upper Gastrointestinal Endoscopy

NCT02643979
View directory record Official record
Conditions
Obesity, Bariatrics, Sleep Apnea Syndromes, Gastric Bypass, Endoscopy
Interventions
Ketofol, Propofol, Saline
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 11, 2020 · Synced Oct 24, 2026, 2:47 PM EDT
Completed Not applicable Interventional Results available

Right Ventricular Hemodynamics Using Cardiac MRI in Patients COPD and OSA

NCT02244957
View directory record Official record
Conditions
Obstructive Sleep Apnea, Chronic Obstructive Pulmonary Disease, Overlap Syndrome
Interventions
Bi-level positive airway pressure (BPAP), Nocturnal oxygen
Device · Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 75 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 28, 2020 · Synced Oct 24, 2026, 2:47 PM EDT
Completed Not applicable Interventional

Sleep Disordered Breathing and Its Impact on Neuro-cognitive Performance and Quality of Life in Parkinson Disease

NCT02034357
View directory record Official record
Conditions
Parkinson's Disease, Sleep Disordered Breathing, Sleep Obstructive Apnea
Interventions
Neurocognitive function, Sleep evaluations
Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Mar 24, 2016 · Synced Oct 24, 2026, 2:47 PM EDT
Completed Not applicable Interventional Results available

Facilitating EndotracheaL Intubation by Laryngoscopy Technique and Apneic Oxygenation Within the Intensive Care Unit: The FELLOW Study

NCT02051816
View directory record Official record
Conditions
Respiratory Failure
Interventions
Video Laryngoscopy, Apneic Oxygenation, Direct Laryngoscopy, No Apneic Oxygenation
Device
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 24, 2017 · Synced Oct 24, 2026, 2:47 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Effect of Dalfampridine (4-AP) on Genioglossus Muscle Activity in Healthy Adults

NCT02656160
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Placebo, Dalfampridine
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 15, 2017 · Synced Oct 24, 2026, 2:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Does myTAP Oral Appliance Therapy Including a Mouth Shield Lessen Periodontitis in Mouth-Breathers Who Snore?

NCT06797089
View directory record Official record
Conditions
Snoring, Mouth Breathing, Daytime Sleepiness, Periodontitis
Interventions
Oral appliance therapy plus scaling and root planing on left or right of mouth
Device
Lead sponsor
Texas A&M University
Other
Eligibility
18 Years to 85 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 30, 2025 · Synced Oct 24, 2026, 2:47 PM EDT
Recruiting Not applicable Interventional

Combination Tonsillectomy and Hypoglossal Nerve Stimulation for OSA Patients With Lateral Pharyngeal Collapse

NCT07724938
View directory record Official record
Conditions
Obstructive Sleep Apnea, Sleep Disordered Breathing
Interventions
Tonsillectomy, HGNS
Procedure · Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Oct 24, 2026, 2:47 PM EDT
Completed Phase 2 Interventional

Study That Tests AD109 in Patients Taking GLP-1 Drugs

NCT06400615
View directory record Official record
Conditions
OSA
Interventions
AD109
Drug
Lead sponsor
Apnimed
Industry
Eligibility
18 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
4
States / cities
Anniston, Alabama • Jacksonville, Florida • Monroe, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 19, 2025 · Synced Oct 24, 2026, 2:47 PM EDT
Completed Not applicable Interventional Results available

DREAM: Does Inhaled Fluticasone REsult in Obstructive Sleep Apnea Manifestations?

NCT01184118
View directory record Official record
Conditions
Lung Disease
Interventions
FP 220 mcg 2 puffs BID
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 65 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 7, 2016 · Synced Oct 24, 2026, 2:47 PM EDT