- Conditions
- Appendicitis
- Interventions
- Polymetric clips, Endoscopic Staplers
- Device · Other
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 26 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
Search Results
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Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 25–48
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- Conditions
- Appendicitis
- Interventions
- Antibiotics only (Zosyn then Augmentin)
- Drug
- Lead sponsor
- Peter Minneci
- Other
- Eligibility
- 7 Years to 17 Years
- Enrollment
- 14 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
- Conditions
- Appendicitis
- Interventions
- Non-operative
- Other
- Lead sponsor
- Nationwide Children's Hospital
- Other
- Eligibility
- 8 Years to 17 Years · Male only
- Enrollment
- 1,076 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2023
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
- Conditions
- Appendicitis Acute, Appendicitis Perforated, Appendicitis With Perforation, Appendicitis Suppurative, Appendicitis Gangrenous
- Interventions
- Discharge on oral antibiotics
- Other
- Lead sponsor
- Cedars-Sinai Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Appendicitis, Cholelithiasis
- Interventions
- Transgastric Appendectomy, Transgastric Cholecystectomy
- Procedure
- Lead sponsor
- University of California, San Diego
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2020
- U.S. locations
- 1
- States / cities
- San Diego, California
- Conditions
- Appendicitis Surgery
- Interventions
- Antibiotic
- Other
- Lead sponsor
- Wake Forest University Health Sciences
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 268 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 1
- States / cities
- Winston-Salem, North Carolina
- Conditions
- Appendicitis (Diagnosis)
- Interventions
- Cefoxitin
- Drug
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 46 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- Appendicitis
- Interventions
- laparoscopic appendectomy, open appendectomy
- Procedure
- Lead sponsor
- Oregon Health and Science University
- Other
- Eligibility
- Up to 18 Years
- Enrollment
- 400 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2011
- U.S. locations
- 3
- States / cities
- Los Angeles, California • Portland, Oregon
- Conditions
- Acute Appendicitis
- Interventions
- Piperacillin + Amoxicillin
- Drug
- Lead sponsor
- Rhode Island Hospital
- Other
- Eligibility
- 5 Years to 18 Years
- Enrollment
- 73 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2015
- U.S. locations
- 1
- States / cities
- Providence, Rhode Island
- Conditions
- Appendicitis
- Interventions
- DS-Ligature Clip
- Device
- Lead sponsor
- Aesculap AG
- Industry
- Eligibility
- 16 Years and older
- Enrollment
- 390 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2013
- U.S. locations
- 2
- States / cities
- Marina del Rey, California • Bethlehem, Pennsylvania
- Conditions
- Acute Uncomplicated Appendicitis
- Interventions
- 1 gm IV ertapenem at enrollment, 1 gm IV ertapenem at Day 2 and oral metronidazole and cefdinir to complete 10 days, Appendectomy
- Drug · Procedure
- Lead sponsor
- Olive View-UCLA Education & Research Institute
- Other
- Eligibility
- 5 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2017
- U.S. locations
- 1
- States / cities
- Sylmar, California
- Conditions
- Intra Abdominal Infections, Appendicitis Acute, Pyelonephritis, Diverticulitis, Epiploic Appendagitis
- Interventions
- TruNAV, an RNA-based blood test for host immune activation by infections
- Diagnostic Test
- Lead sponsor
- True Bearing Diagnostics, Inc.
- Industry
- Eligibility
- 7 Years and older
- Enrollment
- 1,000 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Washington D.C., District of Columbia
- Conditions
- Appendicitis
- Interventions
- Operative management, Drainage or antibiotics
- Procedure · Other
- Lead sponsor
- Yale University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 180 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2029
- U.S. locations
- 1
- States / cities
- New Haven, Connecticut
- Conditions
- Acute Appendicitis
- Interventions
- Appendectomy
- Procedure
- Lead sponsor
- Brian Kenney
- Other
- Eligibility
- Not listed
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
- Conditions
- Perforated Appendicitis
- Interventions
- Initial appendectomy, Interval appendectomy
- Procedure
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 2 Years to 17 Years
- Enrollment
- 23 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2010
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- Appendectomy, Appendicitis, Appendicitis Acute
- Interventions
- Infection-Prediction Algorithm
- Device
- Lead sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
- Other
- Eligibility
- 3 Years to 18 Years
- Enrollment
- 500 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 4
- States / cities
- Chicago, Illinois • Maywood, Illinois • Winfield, Illinois
- Conditions
- Appendicitis
- Interventions
- Multiple standard of care antibiotics for appendicitis, at physicians' discretion
- Drug
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 145 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2026
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Appendicitis, Perforated Appendicitis, Ruptured Appendicitis, Complicated Appendicitis
- Interventions
- Early Appendectomy, Interval Appendectomy, Antibiotics
- Procedure · Drug
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 5 Years to 17 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2020
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- Pregnancy Complications, Acute Appendicitis, Acute Cholecystitis, Biliary Pancreatitis, Bowel Obstruction, Acute Diverticulitis
- Interventions
- non-obstetric acute general surgical disease
- Procedure
- Lead sponsor
- Methodist Health System
- Other
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 3 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2025
- U.S. locations
- 1
- States / cities
- Dallas, Texas
- Conditions
- Perforated Appendicitis
- Interventions
- Ampicillin, gentamicin, clindamycin, flagyl, ceftazidime
- Drug
- Lead sponsor
- Children's Mercy Hospital Kansas City
- Other
- Eligibility
- 1 Month to 18 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2007
- U.S. locations
- 1
- States / cities
- Kansas City, Missouri
- Conditions
- Complicated Appendicitis, Perforated Appendicitis
- Interventions
- ampicillin/clavulanate
- Drug
- Lead sponsor
- Phoenix Children's Hospital
- Other
- Eligibility
- 2 Years to 17 Years
- Enrollment
- 7 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2021
- U.S. locations
- 1
- States / cities
- Phoenix, Arizona
- Conditions
- Acute Appendicitis
- Interventions
- Sulfur hexafluoride lipid-type A microspheres
- Drug
- Lead sponsor
- Children's Mercy Hospital Kansas City
- Other
- Eligibility
- 8 Years to 17 Years
- Enrollment
- 37 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2022
- U.S. locations
- 1
- States / cities
- Kansas City, Missouri
- Conditions
- Ruptured Appendicitis
- Interventions
- early appendectomy, interval appendectomy
- Procedure
- Lead sponsor
- University of Tennessee
- Other
- Eligibility
- Up to 18 Years
- Enrollment
- 128 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2006
- U.S. locations
- 1
- States / cities
- Memphis, Tennessee
- Conditions
- Appendicitis
- Interventions
- Open appendectomy using Alexis Wound Retractor followed by standardized wound closure, Open appendectomy with standardized wound closure
- Device · Procedure
- Lead sponsor
- Santa Barbara Cottage Hospital
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 109 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2008
- U.S. locations
- 1
- States / cities
- Santa Barbara, California