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ClinicalTrials.gov public records Last synced Nov 15, 2026, 9:52 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 140 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Arrhythmias Paroxysmal Clear all

Conditions: Persistent Atrial Fibrillation, Paroxysmal Atrial Fibrillation
Interventions: Not listed
Lead sponsor: The Cleveland Clinic; Other
Eligibility: Not listed
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation, Ventricular Arrhythmia
Interventions: Catheter ablation; Device
Lead sponsor: Heart Rhythm Clinical and Research Solutions, LLC; Other
Eligibility: 18 Years and older
Enrollment: 20,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2028
U.S. locations: 71
States / cities: Birmingham, Alabama • Mobile, Alabama • Chandler, Arizona + 64 more

Conditions: Atrial Fibrillation
Interventions: Multi-Electrode RF Balloon Catheter; Device
Lead sponsor: Biosense Webster, Inc.; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 397 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 37
States / cities: Phoenix, Arizona • Los Angeles, California • Newport Beach, California + 32 more

Conditions: Atrial Fibrillation
Interventions: propafenone; flecainide; sotalol; dofetilide, Radiofrequency catheter ablation; Drug · Device
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 110 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 2
States / cities: Philadelphia, Pennsylvania

Conditions: Atrial Fibrillation, Hypertension
Interventions: Symplicity Spyral™ Multi-Electrode Renal Denervation Catheter, Arctic Front Advance™ Cardiac Cryoablation System; Device
Lead sponsor: Medtronic Vascular; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 102 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2021
U.S. locations: 9
States / cities: Sacramento, California • Burlington, Massachusetts • Marquette, Michigan + 5 more

Conditions: Persistent Atrial Fibrillation, Longstanding Persistent Atrial Fibrillation
Interventions: Synergy Ablation System; Device
Lead sponsor: AtriCure, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 365 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2018
U.S. locations: 49
States / cities: Birmingham, Alabama • Scottsdale, Arizona • Los Angeles, California + 41 more

Conditions: Paroxysmal Supraventricular Tachycardia (PSVT)
Interventions: Not listed
Lead sponsor: Milestone Pharmaceuticals Inc.; Other
Eligibility: Not listed
Enrollment: 354 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Atrial Fibrillation
Interventions: No AAD post Ablation.; Other
Lead sponsor: Prisma Health-Midlands; Other
Eligibility: 18 Years to 80 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Columbia, South Carolina

Conditions: Paroxysmal Atrial Fibrillation
Interventions: FARAPULSE™ Pulsed Field Ablation System; Device
Lead sponsor: Boston Scientific Corporation; Industry
Eligibility: 18 Years and older
Enrollment: 228 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2029
U.S. locations: 25
States / cities: Mobile, Alabama • Scottsdale, Arizona • Oakland, California + 20 more

Conditions: Paroxysmal Atrial Fibrillation
Interventions: SJM Irrigated Cardiac Ablation System, FDA approved Open Irrigated RF Ablation System; Device
Lead sponsor: Abbott Medical Devices; Industry
Eligibility: 18 Years and older
Enrollment: 324 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 27
States / cities: Birmingham, Alabama • Scottsdale, Arizona • Los Angeles, California + 22 more

Conditions: Atrial Fibrillation
Interventions: Yoga training; Other
Lead sponsor: Dhanunjaya Lakkireddy, MD, FACC; Other
Eligibility: 25 Years to 80 Years
Enrollment: 84 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2012
U.S. locations: 1
States / cities: Kansas City, Kansas

Conditions: Atrial Fibrillation, Paroxysmal or Persistent, Atrial Fibrillation and Flutter, Atrial Flutter Typical
Interventions: VARIPULSE™ catheter ablation; Device
Lead sponsor: Vivek Reddy; Other
Eligibility: 18 Years and older
Enrollment: 141 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: New York, New York

Conditions: Paroxysmal Atrial Fibrillation
Interventions: Boston Scientific Cardiac Cryoablation System; Device
Lead sponsor: Boston Scientific Corporation; Industry
Eligibility: 18 Years and older
Enrollment: 458 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 30
States / cities: Phoenix, Arizona • Tucson, Arizona • Jonesboro, Arkansas + 25 more

Conditions: Atrial Fibrillation, Atrial Fibrillation New Onset
Interventions: Cryoablation, Antiarrhythmic drug; Device · Drug
Lead sponsor: Medtronic Cardiac Ablation Solutions; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 225 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 24
States / cities: Birmingham, Alabama • Anchorage, Alaska • Newport Beach, California + 21 more

Conditions: Atrial Fibrillation, Atrial Fibrillation Paroxysmal, Atrial Fibrillation, Persistent
Interventions: Catheter ablation with Standard RF ablation settings, Catheter ablation with High Power Short Duration RF ablation settings; Procedure
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Atrial Fibrillation, Heart Failure
Interventions: Ranolazine, Placebo; Drug
Lead sponsor: Intermountain Health Care, Inc.; Other
Eligibility: 18 Years and older
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Murray, Utah

Conditions: Paroxysmal Atrial Fibrillation
Interventions: Synaptic Cryoablation System; Device
Lead sponsor: Synaptic Medical Corporation; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 128 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 10
States / cities: Phoenix, Arizona • Jonesboro, Arkansas • Los Angeles, California + 6 more

Conditions: Paroxysmal Atrial Fibrillation
Interventions: PVI Ablation, FIRM Ablation; Procedure
Lead sponsor: Indiana University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Paroxysmal Supraventricular Tachycardia (PSVT)
Interventions: Etripamil, Placebo; Drug
Lead sponsor: Milestone Pharmaceuticals Inc.; Other
Eligibility: 18 Years and older
Enrollment: 199 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 26
States / cities: Phoenix, Arizona • Sacramento, California • Littleton, Colorado + 19 more

Conditions: Paroxysmal Atrial Fibrillation
Interventions: Arctic Front™ Cardiac Cryoablation Catheter; Device
Lead sponsor: Medtronic Cardiac Ablation Solutions; Industry
Eligibility: 18 Years and older
Enrollment: 142 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 11
States / cities: Anchorage, Alaska • Stamford, Connecticut • Washington D.C., District of Columbia + 8 more

Conditions: Obstructive Sleep Apnea (OSA), Atrial Fibrillation (Paroxysmal), Palpitations
Interventions: Rhythm Express Wearable System; Device
Lead sponsor: VivaQuant; Industry
Eligibility: 21 Years to 85 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 4
States / cities: Conway, Arkansas • St Louis, Missouri • Charlotte, North Carolina + 1 more

Conditions: Paroxysmal Atrial Fibrillation
Interventions: PVAI followed by adenosine provocation; Procedure
Lead sponsor: Texas Cardiac Arrhythmia Research Foundation; Other
Eligibility: 18 Years to 80 Years
Enrollment: 188 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2020
U.S. locations: 2
States / cities: Austin, Texas

Conditions: Heart Diseases, Arrhythmia, Atrial Fibrillation
Interventions: NAVISTAR® THERMOCOOL® Catheter, Antiarrhythmic drug; Device · Drug
Lead sponsor: Biosense Webster, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 167 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2011
U.S. locations: 13
States / cities: Greenbrae, California • Orlando, Florida • Maywood, Illinois + 9 more

Conditions: Non-paroxysmal Atrial Fibrillation
Interventions: PFA-based PVI+PWI plus adjunctive ablation guided by Electrogram Mapping of Key Substrates, PFA-based PVI+PWI alone; Procedure
Lead sponsor: Xu Liu; Other
Eligibility: 18 Years to 80 Years
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: The Bronx, New York

Search by objective public record fields.

Evaluating the Efficacy and Feasibility of a Novel Wireless ECG Recording System in Monitoring Patients After Atrial Fibrillation Ablation Procedure

Real-world Experience of Catheter Ablation for the Treatment of Arrhythmias

Safety and Effectiveness Evaluation of the Multi-Electrode Radiofrequency Balloon Catheter for the Treatment of Symptomatic Paroxysmal Atrial Fibrillation

A Study of the Effectiveness of Anti-Arrhythmic Medications After Atrial Fibrillation Ablation

Renal Nerve Denervation in Patients With Hypertension and Paroxysmal and Persistent Atrial Fibrillation

ABLATE Post Approval Study - Synergy Ablation Lesions for Non-Paroxysmal Atrial Fibrillation

The PSVT Place Registry.Paroxysmal Supraventricular Tachycardia (PSVT) Registry.

Comparison of Recurrence of Atrial Fibrillation Post Cryoballon Ablation During the 90-day Blanking Period-with and Without Anti-arrhythmic Drug Therapy

ADVENT Post Approval Study

Irrigated Ablation System Evaluation for Atrial Fibrillation (AF)

Yoga on Arrhythmia Burden and Quality of Life in Paroxysmal Atrial Fibrillation

Versatility of a Circular Multielectrode Catheter in the Individualized Recognition & Treatment of Atrial Fibrillation and Related Arrhythmias Using Pulsed Field Energy

Boston Scientific's Cryoballoon in the Treatment of Symptomatic Drug Refractory Paroxysmal Atrial Fibrillation

STOP AF First: Cryoballoon Catheter Ablation in an Antiarrhythmic Drug Naive Paroxysmal Atrial Fibrillation

A Trial of High Power-Short Duration Versus Standard Power-Long Duration Radiofrequency Ablation for Treatment of Atrial Fibrillation

The Use of Ranolazine for Atrial Fibrillation and Diastolic Heart Failure

Treatment of PAF With the Synaptic System

Focal Impulse and Rotor Modulation Ablation Trial for Treatment of Paroxysmal Atrial Fibrillation (FIRMAT-PAF)

Efficacy and Safety of Intranasal MSP-2017 (Etripamil) for the Conversion of PSVT to Sinus Rhythm

STOP AF First Post-Approval Study

Rhythm Express Wearable System vs. Simultaneous Polysomnography for the Diagnosis of Obstructive Sleep Apnea in Adults With Suspected or Observed Atrial Fibrillation

PV Reconnection After PVAI at Different Power Settings and Adenosine Provocation

NAVISTAR® THERMOCOOL® Catheter for the Radiofrequency Ablation of Symptomatic Paroxysmal Atrial Fibrillation

Pulsed-Field Ablation With/Without Electrogram Mapping