Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 15, 2026, 3:59 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 1,804 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Arthritis, Degenerative Clear all

Conditions: Knee Osteoarthritis
Interventions: Sustained Acoustic Device with 2.5% Diclofenac Patch, 1% Diclofenac Topical Gel; Device · Drug
Lead sponsor: ZetrOZ, Inc.; Industry
Eligibility: 35 Years to 80 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 3
States / cities: Stamford, Connecticut • Trumbull, Connecticut • Dryden, New York

Conditions: Knee Arthritis, Knee Osteoarthritis
Interventions: Suzetrigine; Drug
Lead sponsor: Emory University; Other
Eligibility: 18 Years to 95 Years
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 3
States / cities: Atlanta, Georgia

Conditions: Osteoarthritis
Interventions: Liposuction with Local Anesthesia, Intra articular infusion of AD-SVF; Procedure · Biological
Lead sponsor: Ageless Regenerative Institute; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Aventura, Florida

Conditions: Chronic Pain, Osteoarthritis
Interventions: Transcranial Direct Current Stimulation; Device
Lead sponsor: Spaulding Rehabilitation Hospital; Other
Eligibility: 18 Years to 64 Years
Enrollment: 38 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Thumb Basal Joint Osteoarthritis, Postoperative Pain, Joint Replacement Surgery, Joint Replacement
Interventions: suzetrigine 100mg, Acetaminophen; Drug
Lead sponsor: Rothman Institute Orthopaedics; Other
Eligibility: 40 Years to 80 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Osteoarthritis,Knee
Interventions: Not listed
Lead sponsor: University of California, San Francisco; Other
Eligibility: 45 Years to 79 Years
Enrollment: 4,185 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2020
U.S. locations: 3
States / cities: Birmingham, Alabama • Iowa City, Iowa • Boston, Massachusetts

Conditions: Osteoarthritis, Hip, Osteoarthritis, Knee, Lower Back Pain, Pain
Interventions: Oxycodone CR, Tapentadol (CG5503) ER; Drug
Lead sponsor: Johnson & Johnson Pharmaceutical Research & Development, L.L.C.; Industry
Eligibility: 18 Years and older
Enrollment: 1,123 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 40
States / cities: Mesa, Arizona • Tucson, Arizona • Anaheim, California + 37 more

Conditions: Osteoarthritis
Interventions: Bupivacaine; Drug
Lead sponsor: Columbia University; Other
Eligibility: Not listed
Enrollment: 155 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: New York, New York

Conditions: Rheumatoid Arthritis, Degenerative Arthritis, Post Traumatic Arthritis
Interventions: Integra Cadence Total Ankle System; Device
Lead sponsor: Smith & Nephew, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 132 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2025
U.S. locations: 9
States / cities: San Francisco, California • Sarasota, Florida • Buffalo, New York + 5 more

Conditions: Osteoarthritis: Joint Replacement Surgery
Interventions: CLARIX FLO, Saline; Other
Lead sponsor: BioTissue Holdings, Inc; Industry
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019
U.S. locations: 1
States / cities: Orange Park, Florida

Conditions: Knee Osteoarthritis, Total Knee Arthroplasty (TKA)
Interventions: Pain Scale/Medication Log; Other
Lead sponsor: Endeavor Health; Other
Eligibility: 18 Years and older
Enrollment: 375 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Skokie, Illinois

Conditions: Osteoarthritis
Interventions: Ultra Probe Laser System; Device
Lead sponsor: TriTech Manufacturing; Industry
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2006
U.S. locations: 3
States / cities: Phoenix, Arizona • Long Beach, California • Bloomington, Minnesota

Conditions: Musculoskeletal Diseases
Interventions: Multimedia Patient Decision Aids (MM-PtDAs), Comparative Effectiveness Research Summary Guide (CERSG), Questionnaires; Other · Behavioral
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 676 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2021
U.S. locations: 3
States / cities: Houston, Texas

Conditions: Knee Osteoarthritis
Interventions: Realigning knee brace and custom orthodic, Non realigning knee brace and flat orthodic; Device
Lead sponsor: Boston University; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Inflammatory Tissue Disorder, Osteoarthritis, Avascular Necrosis, Post-traumatic Arthritis, Secondary Arthritis
Interventions: Encore Mobile-Bearing Knee; Device
Lead sponsor: Encore Medical, L.P.; Industry
Eligibility: 18 Years and older
Enrollment: 419 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2000 – 2008
U.S. locations: 8
States / cities: Phoenix, Arizona • Fountain Valley, California • Miami, Florida + 5 more

Conditions: Chronic Low Back Pain, Osteoarthritis
Interventions: Fasinumab, Placebo; Drug
Lead sponsor: Regeneron Pharmaceuticals; Industry
Eligibility: 18 Years and older
Enrollment: 63 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 56
States / cities: Phoenix, Arizona • Tucson, Arizona • Anaheim, California + 47 more

Conditions: Osteoarthritis, Knee
Interventions: Acupuncture; Other
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 40 Years to 70 Years
Enrollment: 144 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2016
U.S. locations: 1
States / cities: Charlestown, Massachusetts

Conditions: Osteoarthritis
Interventions: Active Device (Torino II), Sham Device (Torino II); Device
Lead sponsor: Center for Joint Surgery and Sports Medicine, Maryland; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2010
U.S. locations: 1
States / cities: Hagerstown, Maryland

Conditions: Osteoarthritis, Pain
Interventions: Patient may be able to put weight on the operated leg; Behavioral
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years to 90 Years
Enrollment: 33 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2007
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Osteoarthritis
Interventions: Dextrose Prolotherapy, Saline Prolotherapy, At-home physical therapy exercise group; Procedure · Other
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 40 Years to 70 Years
Enrollment: 98 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2016
U.S. locations: 2
States / cities: Madison, Wisconsin

Conditions: Knee Osteoarthritis, Arthritis
Interventions: Exercise Only, Brace Only, Bracing + Exercises; Other · Device
Lead sponsor: Orthopaedic Research Foundation; Other
Eligibility: 21 Years to 80 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Greenwood, Indiana

Conditions: Glenohumeral Osteoarthritis
Interventions: Orthovisc, Control; Device · Drug
Lead sponsor: DePuy Mitek; Industry
Eligibility: 25 Years to 75 Years
Enrollment: 274 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2011
U.S. locations: 13
States / cities: Encinitas, California • Fresno, California • Coral Gables, Florida + 10 more

Conditions: Post-traumatic Osteoarthritis of the Knee
Interventions: FX006 32 mg, TCA IR 40 mg; Drug
Lead sponsor: Pacira Pharmaceuticals, Inc; Industry
Eligibility: 20 Years to 50 Years
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Osteoarthritis of the Knee
Interventions: Diclofenac Sodium Active Topical Patch 1, Diclofenac Sodium Active Topical Patch 2, Placebo patch; Drug
Lead sponsor: Noven Pharmaceuticals, Inc.; Industry
Eligibility: 40 Years to 85 Years
Enrollment: 289 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Jersey City, New Jersey

Search by objective public record fields.

Comparative Usability Evaluation of Sustained Acoustic Medicine (SAM) Devices and Topical Gel for OA Knee Pain

Role of Suzetrigine as a Part of a Multimodal Regimen to Reduce Pain and Opioid Use After Total Knee Arthroplasty

Autologous Adipose-Derived Stromal Cells Delivered Intra-articularly in Patients With Osteoarthritis.

Effects of Transcranial Direct Current Stimulation (tDCS) and Transcranial Ultrasound on Osteoarthritis Pain of the Knee

Journavx to Treat Pain After Thumb Basal Joint Arthroplasty

Multicenter Bone and Joint Health Study

A Study to Evaluate Long-Term Safety of Multiple Doses of Tapentadol (CG5503) Prolonged-Release (PR) and Oxycodone Controlled-Release (CR) in Patients With Chronic Pain

Adductor Canal Block Versus Periarticular Bupivicaine Injection in Total Knee Arthroplasty

Clinical Evaluation of Integra® Cadence™ Total Ankle System in Primary Ankle Joint Replacement (CADENCE)

Amniotic Umbilical Cord Particulate During Total Knee Arthroplasty

How Variations in Pharmacogenomic Profiles Affect Pain and Narcotic Needs Following Total Knee Arthroplasty (TKA)

Study of the Use of Laser Light to Treat Osteoarthritis of the Hand.

IADAPT-Third Phase

Trial of Realignment Therapy for Treatment of Medial Knee Osteoarthritis

Mobile - Bearing Knee Study

Evaluate the Efficacy and Safety of Fasinumab in Patients With Moderate-to-Severe Chronic Low Back Pain and Osteoarthritis of the Hip or Knee

fMRI Study of Expectancy on Acupuncture Treatment Outcomes in Knee OA

Use of Pulsed Electromagnetic Fields for Postoperative Knee Pain

Safety of Non-delayed Weight Bearing After Total Hip Replacement With Non-Cemented Fiber Metal Taper Stem

Joint Injections for Osteoarthritic Knee Pain

Energy Dispersive Bracing for Conservative Treatment of Knee Osteoarthritis

ORTHOVISC Shoulder Osteoarthritis Study

Proof of Concept Study Comparing FX006 to Kenalog®-40 in Patients With Post-Traumatic Osteoarthritis of the Knee

A 4-week Study to Evaluate the Efficacy and Safety of HP-5000 in Subjects With Knee Osteoarthritis