Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 15, 2026, 8:13 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 217–240 of 1,804 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Arthritis, Degenerative Clear all

Conditions: Chronic Fatigue Syndrome, Myalgic Encephalomyelitis, Systemic Exertion Intolerance Disease (SEID), Postural Tachycardia Syndrome (POTS), Neurally Mediated Syncope (NMS)
Interventions: Normal Saline, Oral Rehydration Solution; Drug · Dietary Supplement
Lead sponsor: New York Medical College; Other
Eligibility: 15 Years to 29 Years
Enrollment: 45 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2021
U.S. locations: 1
States / cities: Hawthorne, New York

Conditions: Osteoarthritis, Knee
Interventions: CBD/CBN, CBD/THC, Placebo; Drug
Lead sponsor: Pure Green; Industry
Eligibility: 21 Years and older
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: West Bloomfield, Michigan

Conditions: Osteoarthritis, Fibromyalgia
Interventions: NEM Formulation X, NEM Formulation Y; Dietary Supplement
Lead sponsor: ESM Technologies, LLC; Industry
Eligibility: 18 Years to 100 Years
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2004
U.S. locations: 1
States / cities: Jenks, Oklahoma

Conditions: Ankle Osteoarthritis
Interventions: Axolotl Ambient, "Drug/Placebo: 0.9% Normal Saline"; Biological · Drug
Lead sponsor: Axolotl Biologix; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 3
States / cities: Boise, Idaho • Shreveport, Louisiana • Charlotte, North Carolina

Conditions: Osteoarthritis, Knee
Interventions: any knee joint arthroplasty device; Device
Lead sponsor: Heekin Orthopedic Research Institute; Other
Eligibility: 21 Years to 93 Years
Enrollment: 7,793 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2018
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Osteoarthritis
Interventions: Mini-Posterior surgical approach for total hip arthroplasty, Direct Anterior surgical approach for total hip arthroplasty; Procedure
Lead sponsor: OrthoCarolina Research Institute, Inc.; Other
Eligibility: 25 Years to 80 Years
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: Charlotte, North Carolina

Conditions: Arthritis, Osteoarthritis, Rheumatoid Arthritis
Interventions: People with Arthritis Can Exercise; Behavioral
Lead sponsor: Centers for Disease Control and Prevention; Federal
Eligibility: 18 Years and older
Enrollment: 320 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2005
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Glenohumeral Osteoarthritis
Interventions: Triamcinolone; Drug
Lead sponsor: Milton S. Hershey Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Hershey, Pennsylvania

Conditions: Arthritis, Osteoarthritis, Rheumatoid Arthritis, Fibromyalgia
Interventions: Multicomponent exercise, Nutrition; Behavioral
Lead sponsor: University of South Carolina; Other
Eligibility: 18 Years and older
Enrollment: 401 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Columbia, South Carolina

Conditions: Post-traumatic Osteoarthritis
Interventions: Not listed
Lead sponsor: James Stannard; Other
Eligibility: 18 Years to 50 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Columbia, Missouri

Conditions: Joint Diseases
Interventions: 28 mm ceramic head on ceramic acetabular liner., 28 mm ceramic head on polyethylene liner; Device
Lead sponsor: DePuy Orthopaedics; Industry
Eligibility: 20 Years to 75 Years
Enrollment: 264 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2012
U.S. locations: 2
States / cities: Denver, Colorado • Columbus, Ohio

Conditions: Osteoarthritis, Knee
Interventions: Ropivacaine Continuous Infusion, Ropivacaine Intermittent Bolus, Placebo; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 89 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Knee Osteoarthritis, Musculoskeletal Disease, Surgery
Interventions: PAI, PAI + steroid, PAI + zilretta; Drug
Lead sponsor: Walter Reed National Military Medical Center; Federal
Eligibility: 18 Years and older
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Knee Osteoarthritis
Interventions: Blood Flow Restriction Training (BFRT); Procedure
Lead sponsor: The University of Texas Health Science Center at San Antonio; Other
Eligibility: 60 Years and older
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Osteoarthritis
Interventions: Blood Draw; Procedure
Lead sponsor: National Center for Complementary and Integrative Health (NCCIH); NIH
Eligibility: 30 Years to 65 Years · Male only
Enrollment: 72 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2007
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Osteoarthritis
Interventions: Limitation of Animal Fat and Protein in the Diet, Control; Other
Lead sponsor: Essentia Health; Other
Eligibility: 18 Years to 70 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Traverse City, Michigan

Conditions: Osteoarthritis, Knee, Knee Osteoarthritis, Knee Arthritis, Knee Pain Chronic
Interventions: 4 mL injection of Ampion, 4 mL Injection of Placebo; Biological · Drug
Lead sponsor: Ampio Pharmaceuticals. Inc.; Industry
Eligibility: 40 Years to 85 Years
Enrollment: 168 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017
U.S. locations: 13
States / cities: Birmingham, Alabama • Encinitas, California • Fullerton, California + 10 more

Conditions: Osteoarthritis
Interventions: Health Buddy, Home telehealth technology, Telephone counseling; Device · Other
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 60 Years and older
Enrollment: 38 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: West Los Angeles, California

Conditions: Osteoarthritis, Knee
Interventions: Pentosan Polysulfate Sodium twice weekly, Placebo (Sodium Chloride Injection, 0.9%), Pentosan Polysulfate Sodium Fixed Dose, Pentosan Polysulfate Sodium once weekly; Drug
Lead sponsor: Paradigm Biopharmaceuticals USA (INC); Industry
Eligibility: 18 Years and older
Enrollment: 602 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 29
States / cities: Tempe, Arizona • Tucson, Arizona • Cerritos, California + 20 more

Conditions: Osteoarthritis, Hip, Complications; Arthroplasty
Interventions: Revelation Hip Stem (Revelation); Device
Lead sponsor: Encore Medical, L.P.; Industry
Eligibility: 18 Years and older
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Osteoarthritis, Hip
Interventions: EOS X-Ray; Diagnostic Test
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 99 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Pain, Chronic, Dementia, Mild, Mobility Limitation, Physical Disability, Osteo Arthritis Knee, Mild Cognitive Impairment
Interventions: Tailored Physical Activity Program; Behavioral
Lead sponsor: Drexel University; Other
Eligibility: 60 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Osteoarthitis
Interventions: Low Dose Radiation Therapy; Radiation
Lead sponsor: Abramson Cancer Center at Penn Medicine; Other
Eligibility: 18 Years and older
Enrollment: 113 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 2
States / cities: Philadelphia, Pennsylvania

Conditions: Posttraumatic Osteoarthritis, Anterior Cruciate Ligament (ACL) Rupture
Interventions: Synovial Fluid withdrawal at the preoperative clinic visit, Platelet-Rich Plasma (PRP) preparation and injection, Synovial fluid withdrawal at the time of surgery, 3mL synovial fluid withdrawn at the preoperative visit; Procedure
Lead sponsor: Rush University Medical Center; Other
Eligibility: 18 Years to 50 Years
Enrollment: 99 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Chicago, Illinois

Search by objective public record fields.

Reducing Orthostatic Intolerance With Oral Rehydration in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients

Cannabinoid Tablets for the Treatment of Pain From Osteoarthritis of the Knee

Efficacy & Safety Study of Natural Eggshell Membrane (NEM) for the Treatment of Joint & Connective Tissue Disorders

Evaluating Intra-articular Injection of Axolotl Ambient Compared to Saline in Subjects With Ankle Osteoarthritis

Knee Arthroplasty Registry

A Trial Comparing Mini-posterior Approach and Direct Anterior Approach

Program Evaluation of People With Arthritis Can Exercise

Osteoarthritis Shoulder Injection Study

Self-Directed Exercise Program for Adults With Arthritis

A Biologic Joint Replacement Strategy to Treat Patients With Severe Knee Trauma and Post-Traumatic Knee Osteoarthritis

28 mm Ceramic-on-Ceramic Acetabular Cup Total Hip Replacement Study

A Study to Compare the Effectiveness of Adductor Canal Pain Catheters Following Total Knee Arthroplasty

Use of Corticosteroid in Intraopertive Injections in Total Knee Replacement Surgery.

Blood Flow Restriction Training in Individuals Awaiting Total Knee Replacement

Effects of Osteoarthritis Pain, Morphine, and Placebo on Neuroendocrine Function in Men

The Impact of Dietary Restriction of Animal Protein and Fat on Osteoarthritis

AP-003-C Study to Confirm the Efficacy of Ampion™ in Adults With Pain Due to Severe Osteoarthritis of the Knee

Home Telerehabilitation for Deconditioned Older Adults

Treatment Effects of Subcutaneous Injections of Pentosan Polysulfate Sodium vs Placebo in Participants With Knee OA Pain

Encore Revelation Hip Stem

Variability in Spinopelvic Parameters Among Patients Undergoing Total Hip Arthroplasty

Developing a Nonpharmacological Pain Intervention for Community-dwelling Older Adults With Dementia

Low Dose Radiotherapy for Osteoarthritis

Synovial Fluid Withdrawal or PRP Injection For Acute ACL Tears and Cytokines