Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 15, 2026, 4:27 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 505–528 of 1,804 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Arthritis, Degenerative Clear all

Conditions: Osteoarthritis
Interventions: Acupuncture, Placebo acupuncture, Usual Care; Procedure · Other
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 50 Years and older
Enrollment: 639 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2006
U.S. locations: 2
States / cities: Houston, Texas

Conditions: Hip Osteoarthritis, Rheumatoid Arthritis, Joint Diseases, Avascular Necrosis, Dislocation, Hip, Femoral Neck Fractures, Trochanteric Fractures, Revision Surgeries
Interventions: G7 Dual Mobility with Vivacit-E bearing, G7 Dual Mobility Longevity bearing; Device
Lead sponsor: Zimmer Biomet; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 358 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2037
U.S. locations: 6
States / cities: Little Rock, Arkansas • Jersey City, New Jersey • New York, New York + 3 more

Conditions: Knee Osteoarthritis
Interventions: Diet; Behavioral
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 40 Years to 75 Years
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Osteoarthritis, Knee, Knee Osteoarthritis, Knee Pain Chronic
Interventions: Resiniferatoxin, Zilretta, Placebo; Drug
Lead sponsor: Sorrento Therapeutics, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 124 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 6
States / cities: La Mesa, California • Pasadena, California • Oak Brook, Illinois + 3 more

Conditions: Osteoarthritis, Hip
Interventions: KINCISE, Traditional Handheld Mallet; Device
Lead sponsor: University of Cincinnati; Other
Eligibility: 21 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Osteoarthritis
Interventions: nSTRIDE APS, Saline; Device
Lead sponsor: Zimmer Biomet; Industry
Eligibility: 21 Years to 80 Years
Enrollment: 332 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2020
U.S. locations: 27
States / cities: Birmingham, Alabama • Guntersville, Alabama • Tucson, Arizona + 24 more

Conditions: Knee Osteoarthritis
Interventions: Stepped Exercise for Knee Osteoarthritis; Behavioral
Lead sponsor: Durham VA Medical Center; Federal
Eligibility: 18 Years and older
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Osteoarthritis, Knee
Interventions: Vitamin D (cholecalciferol), Placebo; Dietary Supplement
Lead sponsor: Tufts Medical Center; Other
Eligibility: 45 Years to 90 Years
Enrollment: 146 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Osteoarthritis
Interventions: Evaluation; Other
Lead sponsor: Milton S. Hershey Medical Center; Other
Eligibility: 45 Years and older
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2013
U.S. locations: 1
States / cities: Hershey, Pennsylvania

Conditions: Degenerative Osteoarthritis
Interventions: Benzoyl peroxide gel; Drug
Lead sponsor: Colorado Joint Replacement; Other
Eligibility: 18 Years to 85 Years
Enrollment: 496 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Denver, Colorado

Conditions: Osteoarthritis, Knee
Interventions: Bone Marrow Derived MSCs, Corticosteroid, Bone Marrow Aspirate; Biological · Drug · Device
Lead sponsor: Next Generation Regenerative Medicine LLC; Network
Eligibility: 18 Years to 80 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 3
States / cities: Chesterfield, Missouri • Steubenville, Ohio • Salt Lake City, Utah

Conditions: Osteoarthritis of Hip, Regional Anesthesia, Other Acute Postoperative Pain, Total Hip Arthroplasty, Peripheral Nerve Block, Lumbar Plexus Nerve Block, Parasacaral (Sciatic) Nerve Block
Interventions: Continuous Lumbar Plexus Block, Parasacral Nerve Block, Ropivacine 0.2%, Bupivacaine 0.0625%; Procedure · Drug
Lead sponsor: Rita Merman; Other
Eligibility: 18 Years to 75 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Osteoarthritis, Knee
Interventions: Traumeel® / Zeel® Injectable Solution, Placebo; Drug
Lead sponsor: Biologische Heilmittel Heel GmbH; Industry
Eligibility: 45 Years to 80 Years
Enrollment: 287 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 30
States / cities: Phoenix, Arizona • Tucson, Arizona • Dinuba, California + 24 more

Conditions: Osteoarthitis, Osteoarthritic Knee Pain, Osteoarthritis (OA), Osteoarthritis (OA) of the Knee, Osteoarthritis in the Knee
Interventions: Anteromedial Injection, Anterolateral Injection; Procedure
Lead sponsor: University of Chicago; Other
Eligibility: 40 Years and older
Enrollment: 140 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 5
States / cities: Bolingbrook, Illinois • Chicago, Illinois • La Grange, Illinois + 2 more

Conditions: Osteoarthritis (OA) of the Knee
Interventions: Triamcinolone Acetonide, 0.9% Sodium Chloride Injection as Placebo; Drug
Lead sponsor: Tufts Medical Center; Other
Eligibility: 45 Years and older
Enrollment: 140 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 2
States / cities: Boston, Massachusetts

Conditions: Osteoarthritis, Rheumatoid Arthritis, Traumatic Arthritis, Post Traumatic Deformity, Complications; Arthroplasty, Deformity of Limb
Interventions: Vanguard SSK 360 with PS Bearing, Vanguard SSK 360 with PSC bearing, Vanguard DA 360, Vanguard 360 TiNbN Femur with PS bearing, Vanguard 360 TiNbN Femur with PSC bearing; Device
Lead sponsor: Zimmer Biomet; Industry
Eligibility: 18 Years and older
Enrollment: 255 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2031
U.S. locations: 4
States / cities: Morton Grove, Illinois • Henderson, Nevada • Salt Lake City, Utah + 1 more

Conditions: Knee Osteoarthritis
Interventions: High-speed power training, Slow-speed strength training; Other
Lead sponsor: University of Missouri-Columbia; Other
Eligibility: 55 Years and older
Enrollment: 48 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2008
U.S. locations: 1
States / cities: Columbia, Missouri

Conditions: Total Knee Arthroplasty, Osteo Arthritis Knee, Knee Implant, Knee Injuries
Interventions: Klassic Knee System; Device
Lead sponsor: The University of Tennessee, Knoxville; Other
Eligibility: 18 Years and older
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Osteoarthritis
Interventions: Evicel fibrin sealant; Drug
Lead sponsor: Hospital for Special Surgery, New York; Other
Eligibility: 20 Years to 90 Years
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: New York, New York

Conditions: Degenerative Joint Disease, Osteoarthritis, Knee Injury, Trauma, Connective Tissue Disorder, Pain, Loss of Function
Interventions: Not listed
Lead sponsor: Loma Linda University; Other
Eligibility: 40 Years to 80 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: San Bernardino, California

Conditions: Osteoarthritis
Interventions: Ultrasound, Sham ultrasound; Procedure
Lead sponsor: VA Connecticut Healthcare System; Federal
Eligibility: 40 Years to 89 Years
Enrollment: 33 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: West Haven, Connecticut

Conditions: Osteoarthritis, Rheumatoid Arthritis, Traumatic Arthritis, Knee Arthritis
Interventions: Simplex® Bone Cement, Cobalt™ Bone Cement; Device
Lead sponsor: Zimmer Biomet; Industry
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006
U.S. locations: 1
States / cities: Warsaw, Indiana

Conditions: Hip Osteoarthritis
Interventions: Platelet Rich Plasma Joint Injection, Corticosteroid Injection; Device · Drug
Lead sponsor: LifeBridge Health; Other
Eligibility: 21 Years to 80 Years
Enrollment: 54 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Knee Osteoarthritis
Interventions: Double leg press with partial blood flow restriction, Double leg press without partial blood flow restriction; Device · Other
Lead sponsor: University of Iowa; Other
Eligibility: 45 Years and older · Male only
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Iowa City, Iowa

Search by objective public record fields.

Interaction Between Patient and Healthcare Provider: Response to Acupuncture in Knee Osteoarthritis

G7 Dual Mobility With Vivacit-E or Longevity PMCF

Diet Interventions: Remitted and Evaluated as Complementary Treatments for Pain

Study to Evaluate Intra-articular Resiniferatoxin to Treat Moderate to Severe Pain From Knee Osteoarthritis

KINCISE™ Surgical Automated System in Total Hip Arthroplasty (THA)

Saline-Controlled Study of nSTRIDE APS for Knee Osteoarthritis

Telehealth Stepped Exercise Program for Rural Veterans With Knee Osteoarthritis

Vitamin D to Slow Progression of Knee Osteoarthritis

Electromyography Evaluation of Subscapularis Function After Total Shoulder Arthroplasty

Cutibacterium Dermal Colonization: Implications for Total Hip Arthroplasty

Mesenchymal Stem Cell Therapy for Knee Osteoarthritis

Continuous Lumbar Plexus Block With and Without Parasacral Block in Patients Undergoing Total Hip Replacement

Study of Intra-articular Injections vs Placebo in Patients With Pain From Osteoarthritis of the Knee

Patient Pain and Function in Medial Knee Osteoarthritis After Anteromedial vs Anterolateral Intra-Articular Corticosteroid Injection

Effect of Steroid Injections in a Knee With Osteoarthritis

A Prospective, Clinical Investigation of the Vanguard 360 Revision Knee

High-speed Power Training in Older Adults With Knee Osteoarthritis (OA)

In Vivo Kinematics for Subjects Implanted With Klassic Total Knee Arthroplasty (TKA)

The Use of Evicel to Reduce Blood Loss in Total Knee Replacement Surgery

Comparison of Clinical Outcomes and Performance of Total Knee Replacement Patients Before and After Surgery

Ultrasound (US)-Guided Versus Sham Ultrasound Corticosteroid (CS) Knee Injections

Total Knee Replacement Using Simplex® or Cobalt™ Bone Cement

Platelet Rich Plasma Versus Corticosteroids in Hip Osteoarthritis Pain

Assessment of Efficacy of Low Intensity Resistance Training in Men at Risk for Symptomatic Knee Osteoarthritis