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ClinicalTrials.gov public records Last synced Oct 7, 2026, 4:11 AM EDT

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Showing 25–48 of 178 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Arthroplasties, Hip Replacement Clear all
Terminated Phase 4 Interventional

Post-approval Study of the DURALOC® Option Ceramic-on-Ceramic Hip Prosthesis System

NCT00546598
View directory record Official record
Conditions
Non-inflammatory Joint Disease, Osteoarthritis, Avascular Necrosis, Congenital Hip Dysplasia, Post-traumatic Arthritis
Interventions
Total hip replacement/arthroplasty
Device
Lead sponsor
DePuy Orthopaedics
Industry
Eligibility
21 Years to 80 Years
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2014
U.S. locations
6
States / cities
Atlanta, Georgia • Springfield, Illinois • Cleveland, Ohio + 2 more
Source: ClinicalTrials.gov public record
Updated Nov 30, 2021 · Synced Oct 7, 2026, 4:11 AM EDT
Completed No phase listed Observational

Evaluation of Bone Mineral Density Changes After Total Hip Replacement: A Two-Year Clinical and DXA Analysis

NCT02865447
View directory record Official record
Conditions
Joint Disease
Interventions
total hip arthroplasty implant
Device
Lead sponsor
MicroPort Orthopedics Inc.
Industry
Eligibility
21 Years to 80 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Spokane, Washington
Source: ClinicalTrials.gov public record
Updated Aug 2, 2022 · Synced Oct 7, 2026, 4:11 AM EDT
Completed No phase listed Observational

CREATION Health Readmission Risk Assessment Tool

NCT03424382
View directory record Official record
Conditions
Heart Failure, COPD, Myocardial Infarction, Coronary Artery Bypass Graft, Pneumonia, Total Knee Replacement, Total Hip Replacement, Stroke
Interventions
Not listed
Lead sponsor
AdventHealth
Other
Eligibility
21 Years and older
Enrollment
1,218 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Feb 7, 2020 · Synced Oct 7, 2026, 4:11 AM EDT
Terminated Phase 2 Interventional

Efficacy and Safety Study of 4975 in Patients Undergoing Total Hip Replacement

NCT00683267
View directory record Official record
Conditions
Arthroplasty
Interventions
4975, highly purified capsaicin, Placebo
Drug
Lead sponsor
Anesiva, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
10
States / cities
Birmingham, Alabama • Arcadia, California • Glendale, California + 7 more
Source: ClinicalTrials.gov public record
Updated May 4, 2009 · Synced Oct 7, 2026, 4:11 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Systemic Steroids for Peripheral Nerve Blocks

NCT02464176
View directory record Official record
Conditions
Osteoarthritis, Hip
Interventions
Dexamethasone, Bupivacaine, Epinephrine, Lumbar Plexus Nerve Block, Saline
Drug · Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 90 Years
Enrollment
115 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 31, 2018 · Synced Oct 7, 2026, 4:11 AM EDT
Completed Not applicable Interventional Results available

ABC/Trident® Ceramic Post Approval Study

NCT00960206
View directory record Official record
Conditions
Arthroplasty, Replacement, Hip
Interventions
Trident® Ceramic Insert/Trident® AD HA Acetabular Shell, Alumina Insert/PSL® Microstructured Acetabular Shell or Secur-Fit® HA PSL® Acetabular Shell, OmniFit® Series II Insert/OmniFit® PSL® Microstructured Acetabular Shell
Device
Lead sponsor
Stryker Orthopaedics
Industry
Eligibility
21 Years to 75 Years
Enrollment
413 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2010
U.S. locations
6
States / cities
Boca Raton, Florida • Atlanta, Georgia • Indianapolis, Indiana + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 3, 2017 · Synced Oct 7, 2026, 4:11 AM EDT
Terminated Not applicable Interventional

Post Approval Study: NOVATION Ceramic Articulation Hip System

NCT00715143
View directory record Official record
Conditions
Total Hip Replacement (Non-inflammatory)
Interventions
Novation Ceramic
Device
Lead sponsor
Exactech
Industry
Eligibility
21 Years and older
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2021
U.S. locations
5
States / cities
Fort Lauderdale, Florida • Cumming, Georgia • Worcester, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 31, 2022 · Synced Oct 7, 2026, 4:11 AM EDT
Completed Phase 2 Interventional Results available

Effectiveness of Two Types of Treatment in Restoring Muscle After Hip or Knee Surgery

NCT00393848
View directory record Official record
Conditions
Hip Fracture, Osteoarthritis, Femur Head Necrosis
Interventions
Essential amino acid supplement, Ketoconazole, Placebo
Drug
Lead sponsor
University of Arkansas
Other
Eligibility
30 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Jun 2, 2014 · Synced Oct 7, 2026, 4:11 AM EDT
Enrolling by invitation No phase listed Observational

A Multicenter, Post-Market Clinical Follow-up Study of Subjects With the REDAPT™ System Monolithic Sleeveless/Sleeved Stem and/or Fully Porous Acetabular Shell With XLPE Liner and/or Modular Shell Components Previously Implanted

NCT03610789
View directory record Official record
Conditions
Hip Replacement
Interventions
REDAPT
Device
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years and older
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2034
U.S. locations
4
States / cities
Rancho Mirage, California • San Diego, California • New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 6, 2025 · Synced Oct 7, 2026, 4:11 AM EDT
Completed Not applicable Interventional

A Randomized Study of Approaches in Total Hip Arthroplasty

NCT01613508
View directory record Official record
Conditions
Total Hip Replacement
Interventions
Direct Anterior Approach, Mini-Posterior Approach
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
20 Years to 100 Years
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 5, 2018 · Synced Oct 7, 2026, 4:11 AM EDT
Terminated Phase 4 Interventional Results available

Spinal Anesthesia in Total Hip Arthroplasty

NCT02818894
View directory record Official record
Conditions
Total Hip Arthroplasty
Interventions
Lidocaine, Bupivacaine
Drug
Lead sponsor
Thomas L Bradbury
Other
Eligibility
18 Years to 90 Years
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 23, 2022 · Synced Oct 7, 2026, 4:11 AM EDT
Completed Not applicable Interventional Results available

Self-adherent Absorbent Silver Dressing in Adults After Hip or Knee Arthroplasty

NCT03016078
View directory record Official record
Conditions
Arthroplasties, Hip Replacement, Arthroplasties, Knee Replacement
Interventions
Mepilex Border Post-Op Ag
Device
Lead sponsor
Molnlycke Health Care AB
Industry
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Gilbert, Arizona
Source: ClinicalTrials.gov public record
Updated Feb 14, 2018 · Synced Oct 7, 2026, 4:11 AM EDT
Recruiting Phase 3 Interventional

Opioid-Sparing Joint Replacement

NCT07348627
View directory record Official record
Conditions
Pain Management, Opioid Consumption
Interventions
Placebo, Oxycodone 5 mg, Multimodal Non-Opioid Analgesia
Drug · Other
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 17, 2026 · Synced Oct 7, 2026, 4:11 AM EDT
Completed Not applicable Interventional Results available

LFIT™ Anatomic CoCr Femoral Heads With X3® Polyethylene Insert Study

NCT00510458
View directory record Official record
Conditions
Arthroplasty, Replacement, Hip
Interventions
LFIT™ Femoral Heads With X3® Insert
Device
Lead sponsor
Stryker Orthopaedics
Industry
Eligibility
18 Years and older
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2016
U.S. locations
5
States / cities
Miami, Florida • Boston, Massachusetts • Ocean City, New Jersey + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 12, 2018 · Synced Oct 7, 2026, 4:11 AM EDT
Recruiting Phase 3 Interventional Accepts healthy volunteers

Suzetrigine in Total Hip Arthroplasty

NCT07226700
View directory record Official record
Conditions
Total Hip Arthroplasty (THA), Total Hip Arthroplasty \(THA\), Total Hip Replacement, Total Hip Replacement Surgery, Total Hip Replacements, Total Hip Replacement Arthroplasty, Suzetrigine, Pain Management, Pain, Nav 1.8, JOURNAVX, Opioid Cessation, Opioid Consumption, Postoperative, Multimodal Analgesia, Randomized Controlled Trial, Randomized Controlled Study, Randomized Controlled Trials
Interventions
Suzetrigine, Placebo
Drug · Other
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 80 Years
Enrollment
210 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Oct 7, 2026, 4:11 AM EDT
Not listed No phase listed Observational

Origin Stem and Logical Cup Post Market Clinical Follow-up

NCT04123600
View directory record Official record
Conditions
Hip Disease
Interventions
Origin Stem and Logical Cup
Device
Lead sponsor
Signature Orthopaedics
Industry
Eligibility
18 Years to 75 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 22, 2021 · Synced Oct 7, 2026, 4:11 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Venous Blood Flow Velocity: Electrical Foot Stimulation Compared to Intermittent Pneumatic Compression of the Foot

NCT00114608
View directory record Official record
Conditions
Deep Vein Thrombosis, Pulmonary Embolism
Interventions
The Focus™ Neuromuscular Stimulation System
Device
Lead sponsor
University at Buffalo
Other
Eligibility
50 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Mar 11, 2008 · Synced Oct 7, 2026, 4:11 AM EDT
Terminated Phase 4 Interventional Results available

PROUD Study - Preventing Opioid Use Disorders

NCT04766996
View directory record Official record
Conditions
Anesthesia, Opioid Use
Interventions
Guided mindfulness exercises, Self-administered aromatherapy, Baby aspirin, Tylenol/Acetaminophen, Pregabalin, Prednisone, Meloxicam, Prilosec, Tramadol, Voltaren, Zofran, Pepcid, Reglan, Versed, Lidocaine, Propofol, Ancef, Tranexamic Acid (TXA), Decadron, Bupivacaine hydrochloride, Toradol
Behavioral · Other · Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 22, 2023 · Synced Oct 7, 2026, 4:11 AM EDT
Completed Phase 3 Interventional Results available

Exercise and Testosterone Therapy in Elderly Men With Physical Frailty

NCT00345969
View directory record Official record
Conditions
Physical Frailty, Hip Fracture, Elective Hip Replacement, Hypogonadism
Interventions
Transdermal Testosterone gel (1%), Supervised exercise training
Drug · Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
65 Years and older · Male only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 22, 2018 · Synced Oct 7, 2026, 4:11 AM EDT
Completed No phase listed Observational

A Clinical Investigation of the Taperloc® Microplasty™ Hip System

NCT00699309
View directory record Official record
Conditions
Osteoarthritis, Rheumatoid Arthritis, Avascular Necrosis
Interventions
Not listed
Lead sponsor
Biomet Orthopedics, LLC
Industry
Eligibility
18 Years and older
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2013
U.S. locations
4
States / cities
Beaufort, South Carolina • Greenville, South Carolina • Plano, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 21, 2017 · Synced Oct 7, 2026, 4:11 AM EDT
Completed Phase 4 Interventional

Effect of Prophylactic Antibiotics on Intra-Operative Culture Results

NCT01174212
View directory record Official record
Conditions
Infection, Arthroplasty
Interventions
Prophylactic Antibiotics, Control Antibiotics
Procedure
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 90 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
2
States / cities
Chicago, Illinois • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 31, 2012 · Synced Oct 7, 2026, 4:11 AM EDT
Completed Not applicable Interventional

Study Comparing Mini-Incision Versus 2-Incision Approach for Total Hip Replacement

NCT00594893
View directory record Official record
Conditions
Osteoarthritis
Interventions
Mini Incision Approach, 2 Incision Approach
Procedure
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 31, 2012 · Synced Oct 7, 2026, 4:11 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Marathon and Enduron Polyethylene at Long-Term Follow-up

NCT02508428
View directory record Official record
Conditions
Osteoarthritis, Arthritis, Joint Diseases, Musculoskeletal Diseases, Rheumatic Diseases
Interventions
Hip Replacement with crosslinked Marathon polyethylene, Hip Replacement with noncrosslinked Enduron polyethylene
Device
Lead sponsor
Anderson Orthopaedic Research Institute
Other
Eligibility
Not listed
Enrollment
230 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2017
U.S. locations
1
States / cities
Alexandria, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 1, 2020 · Synced Oct 7, 2026, 4:11 AM EDT
Withdrawn No phase listed Observational

Hip Replacement in a High Volume Community Hospital: Effect on Length of Stay and Hospital Cost

NCT01857505
View directory record Official record
Conditions
Hip Osteoarthritis
Interventions
Not listed
Lead sponsor
Anne Arundel Health System Research Institute
Other
Eligibility
40 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
Annapolis, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 18, 2014 · Synced Oct 7, 2026, 4:11 AM EDT