Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 15, 2026, 12:27 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 73–96 of 102 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Articular Cartilage Clear all

Conditions: Osteoarthritis
Interventions: Nonsteroidal anti-inflammatory drugs (NSAIDs), Acetaminophen; Drug
Lead sponsor: Stanford University; Other
Eligibility: 50 Years to 85 Years
Enrollment: 900 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1996 – 2001
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Anterior Cruciate Ligament Injuries, Exercise, Cartilage, Articular, Knee Injuries, Osteoarthritis, Osteoarthritis, Knee, Arthritis, Joint Diseases
Interventions: Physical Activity Promotion; Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 35 Years
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Torn Meniscus
Interventions: Mechanical Debridement, Paragon T2, Lavage debridement, RF- based Debridement; Device · Procedure
Lead sponsor: Smith & Nephew, Inc.; Industry
Eligibility: 18 Years to 60 Years
Enrollment: 165 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2012
U.S. locations: 10
States / cities: Phoenix, Arizona • Los Angeles, California • Aurora, Colorado + 6 more

Conditions: Anterior Cruciate Ligament Rupture
Interventions: Initial graft tension during ACL reconstruction surgery; Procedure
Lead sponsor: Rhode Island Hospital; Other
Eligibility: 15 Years to 50 Years
Enrollment: 168 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2024
U.S. locations: 2
States / cities: Providence, Rhode Island

Conditions: Articular Cartilage Disorder, Degeneration; Articular Cartilage, Chronic Cartilage Injury, Acute Cartilage Injury, Defect of Articular Cartilage
Interventions: Chondrofix Osteochondral Allograft; Procedure
Lead sponsor: Zimmer Orthobiologics, Inc.; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 29 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 5
States / cities: Cos Cob, Connecticut • New Haven, Connecticut • Greenwood, Indiana + 2 more

Conditions: Injuries, Knee
Interventions: Single Portal Knee Arthroscopy, Two Portal Knee Arthroscopy; Procedure
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 21 Years to 65 Years
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Chondrosis, Patellar Articular Cartilage Lesions, Trochlear Articular Cartilage Lesions
Interventions: Not listed
Lead sponsor: Orthopaedic Research Foundation; Other
Eligibility: 18 Years to 50 Years
Enrollment: 35 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 1995 – 2005
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Anterior Cruciate Ligament Reconstruction
Interventions: Tranexamic Acid, Placebos; Drug
Lead sponsor: Stanford University; Other
Eligibility: 18 Years to 30 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2027
U.S. locations: 1
States / cities: Stanford, California

Conditions: Pilon Fracture
Interventions: N-acetylcysteine, Saline; Drug
Lead sponsor: University of Missouri-Columbia; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2026
U.S. locations: 1
States / cities: Columbia, Missouri

Conditions: Osteoarthritis, Knee
Interventions: TissueGene-C, Normal Saline; Biological · Drug
Lead sponsor: Kolon TissueGene, Inc.; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 102 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 5
States / cities: Pinellas Park, Florida • Baltimore, Maryland • Philadelphia, Pennsylvania + 2 more

Conditions: Meniscus Tears, Loose Bodies, Articular Osteoarthritis, Articular or Capsular Trauma
Interventions: VisionScope Imaging (VSI) Exam; Procedure
Lead sponsor: VisionScope Technologies; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 105 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 7
States / cities: Los Angeles, California • Redwood City, California • Santa Monica, California + 4 more

Conditions: Osteoarthritis
Interventions: LNA043, Placebo; Biological · Other
Lead sponsor: Novartis Pharmaceuticals; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 142 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2022
U.S. locations: 11
States / cities: Phoenix, Arizona • La Mesa, California • Sacramento, California + 8 more

Conditions: Cartilage Injury, Cartilage Damage
Interventions: Cryopreserved Osteochondral Allograft; Procedure
Lead sponsor: AlloSource; Industry
Eligibility: 18 Years to 60 Years
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2028
U.S. locations: 3
States / cities: Chicago, Illinois • Lexington, Kentucky • Cincinnati, Ohio

Conditions: Articular Cartilage Defect, Articular Cartilage Degeneration
Interventions: Autologous Chondrocyte Implantation (CartiLife®); Drug
Lead sponsor: Biosolution Co., Ltd.; Industry
Eligibility: 18 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 5
States / cities: Irvine, California • La Mesa, California • Lafayette, Louisiana + 1 more

Conditions: Tendonitis, Bursitis
Interventions: Ketoprofen Topical Patch 20%, Placebo; Drug · Other
Lead sponsor: Alkemira SA; Industry
Eligibility: 18 Years and older
Enrollment: 381 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2008
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Degeneration; Articular Cartilage, Knee, Rheumatoid Arthritis, Osteoarthritis, Knee
Interventions: Clinic-based outpatient exercise group, Community-based exercise group; Other
Lead sponsor: University of Pittsburgh; Other
Eligibility: 60 Years and older
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Hip Osteoarthritis, Hip Impingement Syndrome, Cartilage Damage, Fibrosis
Interventions: Losartan, Placebo; Drug · Other
Lead sponsor: Steadman Philippon Research Institute; Other
Eligibility: 18 Years to 60 Years
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020
U.S. locations: 1
States / cities: Vail, Colorado

Conditions: Instability, Joint, Shoulder Dislocation, Shoulder Injuries, Shoulder Subluxation, Anterior Shoulder Instability, Glenoid; Dislocation
Interventions: MRI; Diagnostic Test
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 50 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Knee Cartilage Defects
Interventions: CARTISTEM® + Debridement, Debridement; Biological · Procedure
Lead sponsor: Medipost, Inc.; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 37
States / cities: Birmingham, Alabama • Scottsdale, Arizona • Tempe, Arizona + 30 more

Conditions: Knee Osteoarthritis
Interventions: Gait Retraining; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 35 Years to 80 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Degenerative Lesion of Articular Cartilage of Knee, Osteochondritis Dissecans
Interventions: DeNovo NT, Natural Tissue Graft; Other
Lead sponsor: Zimmer Orthobiologics, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 160 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2021
U.S. locations: 15
States / cities: Huntsville, Alabama • San Diego, California • Aurora, Colorado + 12 more

Conditions: Musculoskeletal Pain, Knee Osteoarthritis, Cartilage Injury, Cartilage Degeneration
Interventions: Autologous Mesenchymal Stem Cells; Biological
Lead sponsor: University Hospitals Cleveland Medical Center; Other
Eligibility: 18 Years to 60 Years
Enrollment: 16 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2026
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Knee Pain Chronic, Knee Osteoarthritis, Cartilage Damage, Cartilage Defects of the Knee, Cartilage or Osteochondral Defects in the Knee, Cartilage Lesion
Interventions: BioPoly, surgical standard of care (SSOC); Device · Procedure
Lead sponsor: BioPoly LLC; Industry
Eligibility: 30 Years to 65 Years
Enrollment: 152 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 6
States / cities: Redwood City, California • Fort Wayne, Indiana • Indianapolis, Indiana + 3 more

Conditions: Osteoarthritis
Interventions: Not listed
Lead sponsor: University of California, San Francisco; Other
Eligibility: 40 Years and older · Female only
Enrollment: 18 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2007
U.S. locations: 1
States / cities: San Francisco, California

Search by objective public record fields.

Toward Better Outcomes in Osteoarthritis

Preventing Posttraumatic Osteoarthritis With Physical Activity Promotion

Knee Articular Cartilage Debridement in Conjunction With Partial Meniscectomy

Initial Graft Tension and ACL Surgery

Chondrofix Osteochondral Allograft Prospective Study

Controlled Trial to Compare Single Versus Two Portal Knee Arthroscopy Techniques

Autologous Chondrocyte Implantation in the Patellofemoral Joint

The Effects of Tranexamic Acid on Joint Inflammation and Cartilage Health in Anterior Cruciate Ligament Injured Patients

Pilon Fracture With Intra-articular Injection of N-Acetylcysteine (Pilon NAC)

Study of TG-C in Patients With Grade 3 Degenerative Joint Disease of the Knee

Clinical Efficacy Study Comparing VisionScope Imaging (VSI) to Magnetic Resonance Imaging (MRI) in Injuries of the Knee

Study of Safety, Tolerability, Preliminary Efficacy of Intra-articular LNA043 Injections in Patients With Articular Cartilage Lesions and Knee Osteoarthritis.

Prospective Evaluation of ProChondrix CR for Repair of Articular Cartilage Defects on Femoral Condyle and Patella

Phase 2 Clinical Trial of CartiLife® in the United States

Efficacy and Safety of Ketoprofen Topical Patch 20% in the Treatment of Pain Associated With Shoulder, Elbow or Knee Tendonitis or Bursitis

Comparison of Treatments Following Total Knee Replacement

Losartan to Improve Hip Microfracture

Quantitative MRI of Glenohumeral Cartilage & Labrum in Shoulder Instability

Phase 3 Pivotal Trial Comparing CARTISTEM® and Surgical Comparator for Knee Cartilage Lesions and Osteoarthritis

Loaded and Unloaded Magnetic Resonance (MR) Imaging of Meniscus-Cartilage-Trabecular Bone in Osteoarthritis

DeNovo NT Longitudinal Data Collection (LDC) Knee Study

Impact of Mesenchymal Stem Cells in Knee Osteoarthritis

BioPoly® Partial Resurfacing Knee Implant IDE

A Longitudinal Study of Osteoarthritis (OA) Disease Progression Measured by MRI, dGEMRIC, and Radiography