- Conditions
- Amputation
- Interventions
- AMI transtibial amputation, Standard transtibial amputation
- Procedure
- Lead sponsor
- Massachusetts Institute of Technology
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 14 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2025
- U.S. locations
- 1
- States / cities
- Cambridge, Massachusetts
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Showing 25–48
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- Conditions
- Arthroplasty Replacement Knee, Knee Prosthesis
- Interventions
- Subjects implanted with DePuy LCS PS RP TKA, Subjects implanted with DePuy Sigma PS RP TKA
- Device
- Lead sponsor
- The University of Tennessee, Knoxville
- Other
- Eligibility
- 20 Years to 85 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2011
- U.S. locations
- 4
- States / cities
- Denver, Colorado • Knoxville, Tennessee
- Conditions
- Non-inflammatory Degenerative Joint Disease
- Interventions
- 36 mm ceramic head on a ceramic acetabular liner, 28 mm ceramic head on a polyethylene acetabular liner
- Device
- Lead sponsor
- DePuy Orthopaedics
- Industry
- Eligibility
- 20 Years to 75 Years
- Enrollment
- 243 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2003 – 2013
- U.S. locations
- 5
- States / cities
- Sacramento, California • Denver, Colorado • Winston-Salem, North Carolina + 2 more
- Conditions
- Post-Meniscectomy Pain Syndrome, Osteoarthritis, Knee
- Interventions
- NUsurface® Meniscus Implant
- Device
- Lead sponsor
- Phoenix Kinetics
- Industry
- Eligibility
- 30 Years to 75 Years
- Enrollment
- 115 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2024
- U.S. locations
- 13
- States / cities
- Phoenix, Arizona • La Mesa, California • Long Beach, California + 10 more
- Conditions
- Dental Prosthesis Failure, Dental Prosthesis Complication
- Interventions
- CEREC Cercon 4D
- Device
- Lead sponsor
- Dentsply Sirona Implants and Consumables
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 82 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2031
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- Erectile Dysfunction, Penile Prosthesis; Complications, Infection or Inflammation
- Interventions
- Chlorhexidine, Gentamicin, Rifampin
- Drug
- Lead sponsor
- Rush University Medical Center
- Other
- Eligibility
- Male only
- Enrollment
- 200 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2027
- U.S. locations
- 3
- States / cities
- Mountain View, California • Chicago, Illinois • Des Plaines, Illinois
- Conditions
- Retinitis Pigmentosa
- Interventions
- Implant of Argus II Retinal Prosthesis
- Device
- Lead sponsor
- Second Sight Medical Products
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2019
- U.S. locations
- 7
- States / cities
- Los Angeles, California • San Francisco, California • Baltimore, Maryland + 3 more
- Conditions
- Surgical Wound, Revision Total Knee Arthroplasty, Wounds and Injuries, Joint Disease, Musculoskeletal Disease, Prosthesis-Related Infections, Infection, Postoperative Complications, Pathologic Processes
- Interventions
- Closed Incision Negative Pressure Therapy (ciNPT), Standard of Care Dressing
- Device
- Lead sponsor
- KCI USA, Inc
- Industry
- Eligibility
- 22 Years and older
- Enrollment
- 294 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2019
- U.S. locations
- 17
- States / cities
- Weston, Florida • Tucker, Georgia • New Orleans, Louisiana + 10 more
- Conditions
- Doctor Efficiency, Dental Prosthesis Fit
- Interventions
- Navigated Photogrammetry, Standard Photogrammetry
- Device
- Lead sponsor
- X-Nav Technologies, LLC
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 4 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- Washington D.C., District of Columbia
- Conditions
- Neurogenic Bladder, Urinary Retention, Urologic Diseases
- Interventions
- Connected Catheter
- Device
- Lead sponsor
- Spinal Singularity
- Industry
- Eligibility
- 18 Years and older · Male only
- Enrollment
- 8 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2021
- U.S. locations
- 3
- States / cities
- Downey, California • San Diego, California • Washington D.C., District of Columbia
- Conditions
- Lower Limb Amputation Below Knee
- Interventions
- Fixed stiffness prosthesis, Automatic stiffness prosthesis
- Device
- Lead sponsor
- Seattle Institute for Biomedical and Clinical Research
- Other
- Eligibility
- 18 Years to 79 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Seattle, Washington
- Conditions
- Joint Diseases
- Interventions
- 28 mm ceramic head on ceramic acetabular liner., 28 mm ceramic head on polyethylene liner
- Device
- Lead sponsor
- DePuy Orthopaedics
- Industry
- Eligibility
- 20 Years to 75 Years
- Enrollment
- 264 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2003 – 2012
- U.S. locations
- 2
- States / cities
- Denver, Colorado • Columbus, Ohio
- Conditions
- Upper Limb Amputation Below Elbow
- Interventions
- Cutaneous Prosthesis Control System
- Device
- Lead sponsor
- Phantom Neuro Inc.
- Industry
- Eligibility
- 21 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 2
- States / cities
- Buffalo, New York • Austin, Texas
- Conditions
- Bilateral Vestibular Hypofunction, Bilateral Vestibular Deficiency, Bilateral Vestibulopathy, Gentamicin Ototoxicity, Aminoglycoside Toxicity, Vestibular Diseases, Sensation Disorders, Labyrinth Diseases, Other Disorders of Vestibular Function
- Interventions
- Labyrinth Devices MVI™ Multichannel Vestibular Implant System
- Device
- Lead sponsor
- Johns Hopkins University
- Other
- Eligibility
- 22 Years to 90 Years
- Enrollment
- 32 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2029
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Retinitis Pigmentosa
- Interventions
- Argus II
- Device
- Lead sponsor
- University of California, Santa Barbara
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 6 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2023
- U.S. locations
- 3
- States / cities
- Santa Barbara, California • Baltimore, Maryland • Ann Arbor, Michigan
- Conditions
- Amputation of Lower Limb
- Interventions
- Prosthetic foot, Physical therapy
- Other
- Lead sponsor
- Northwestern University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2029
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Traumatic Amputation of Arm
- Interventions
- Advanced upper limb prosthetic device IMU controlled, Advanced upper limb prosthetic EMG-PR controlled
- Device
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 52 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2018
- U.S. locations
- 4
- States / cities
- Tampa, Florida • New York, New York • Providence, Rhode Island + 1 more
- Conditions
- Amputation, Diabetes Complications
- Interventions
- Custom prosthetic socket with mechanical vibrators (stochastic resonance), Conventional prosthetic socket (current clinical practice)
- Device
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 17 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2018
- U.S. locations
- 1
- States / cities
- Seattle, Washington
- Conditions
- Erectile Dysfunction (ED)
- Interventions
- Rigicon Infla10® Inflatable Penile Prosthesis (IPP)
- Device
- Lead sponsor
- Rigicon, Inc.
- Industry
- Eligibility
- 22 Years and older · Male only
- Enrollment
- 182 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2029
- U.S. locations
- 4
- States / cities
- Coral Gables, Florida • Tampa, Florida • Atlanta, Georgia + 1 more
- Conditions
- Amputation
- Interventions
- eOPRA Implant System for Transtibial Amputees and Magnetic Bead Tracking System
- Device
- Lead sponsor
- Brigham and Women's Hospital
- Other
- Eligibility
- 22 Years to 65 Years
- Enrollment
- 7 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 2
- States / cities
- Boston, Massachusetts • Cambridge, Massachusetts
- Conditions
- Missing Teeth
- Interventions
- Treatment with the JUVORA™ Dental Disc
- Device
- Lead sponsor
- Juvora Ltd.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2022
- U.S. locations
- 1
- States / cities
- San Antonio, Texas
- Conditions
- Peripheral Neuropathy With Type 2 Diabetes, Peripheral Neuropathy Grade 2 or Greater, Balance, Balance Impairment, Gait Disorders, Fatigue, Balance Disorders, Physical Activities
- Interventions
- External, lower limb sensory prosthesis
- Device
- Lead sponsor
- RxFunction Inc.
- Industry
- Eligibility
- 60 Years and older
- Enrollment
- 18 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Jacksonville, Florida
- Conditions
- Amputation, Traumatic, Traumatic Amputation of Lower Extremity, Wounds and Injuries
- Interventions
- Otto Bock prosthesis, Ossur prosthesis, Freedom Innovations prosthesis
- Device
- Lead sponsor
- VA Eastern Colorado Health Care System
- Federal
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2013 – 2018
- U.S. locations
- 1
- States / cities
- Boulder, Colorado
- Conditions
- Erectile Dysfunction (ED)
- Interventions
- Exparel/bupivacaine mixture
- Drug
- Lead sponsor
- Wake Forest University Health Sciences
- Other
- Eligibility
- 21 Years and older · Male only
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Winston-Salem, North Carolina