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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Asthma Acute Clear all
Completed Not applicable Interventional Results available

Relief of Acute Bronchoconstriction/Asthma Using the Non-Invasive AlphaCore Device

NCT01532817
View directory record Official record
Conditions
Asthma
Interventions
AlphaCore
Device
Lead sponsor
ElectroCore INC
Industry
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
3
States / cities
San Diego, California • Minneapolis, Minnesota • Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 8, 2018 · Synced Jun 10, 2026, 10:17 PM EDT
Completed Phase 2 Interventional

Study Evaluating the Safety and Efficacy of MN-221 as an Adjunct to Standard Therapy in Subjects Experiencing an Acute Exacerbation of Asthma

NCT00838591
View directory record Official record
Conditions
Asthma
Interventions
MN-221, Placebo
Drug
Lead sponsor
MediciNova
Industry
Eligibility
18 Years to 65 Years
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
15
States / cities
Loma Linda, California • San Diego, California • Sylmar, California + 11 more
Source: ClinicalTrials.gov public record
Updated Sep 4, 2013 · Synced Jun 10, 2026, 10:17 PM EDT
Completed Not applicable Interventional Results available

Effectiveness of the Aeroneb in Acute Severe Asthma

NCT03029156
View directory record Official record
Conditions
Asthma Exacerbation
Interventions
Aeroneb nebulizer, Small volume jet nebulizer
Device
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years to 55 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 18, 2023 · Synced Jun 10, 2026, 10:17 PM EDT
Not listed Not applicable Interventional

Leo Study Unstable Asthma

NCT05308277
View directory record Official record
Conditions
Asthma in Children
Interventions
Leo device monitoring
Device
Lead sponsor
ResMed
Industry
Eligibility
2 Years to 18 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 25, 2022 · Synced Jun 10, 2026, 10:17 PM EDT
Completed Not applicable Interventional Results available

Acute Effect of Mometasone on Beta-adrenergic Airway and Airway Vascular Relaxation in Severe Asthma

NCT01210170
View directory record Official record
Conditions
Asthma
Interventions
placebo, mometasone 400 mcg, mometasone 200 mcg
Drug
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 65 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Nov 20, 2017 · Synced Jun 10, 2026, 10:17 PM EDT
Completed Not applicable Interventional

Peak Expiratory Flow Rate for Emergency Department Management of Acute Asthma Exacerbation

NCT03420651
View directory record Official record
Conditions
Asthma
Interventions
Peak Expiratory Flow Rate (PEFR), Standard Clinical Judgement
Other
Lead sponsor
Hennepin Healthcare Research Institute
Other
Eligibility
16 Years to 55 Years
Enrollment
188 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 20, 2023 · Synced Jun 10, 2026, 10:17 PM EDT
Terminated Phase 2 Interventional Results available

Study Evaluating the Safety and Effects of MN-221 in Subjects Experiencing an Acute Exacerbation of Asthma

NCT00683449
View directory record Official record
Conditions
Asthma, Status Asthmaticus
Interventions
Dose Group 1, MN-221 placebo, Dose Group 2, Dose Group 3
Drug
Lead sponsor
MediciNova
Industry
Eligibility
18 Years to 55 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
9
States / cities
Phoenix, Arizona • Los Angeles, California • Sylmar, California + 6 more
Source: ClinicalTrials.gov public record
Updated Oct 6, 2011 · Synced Jun 10, 2026, 10:17 PM EDT
Terminated Phase 4 Interventional Results available

Azithromycin for Children Hospitalized With Asthma

NCT02003911
View directory record Official record
Conditions
Asthma
Interventions
Azithromycin, Placebo
Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
4 Years to 12 Years
Enrollment
159 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Aug 12, 2020 · Synced Jun 10, 2026, 10:17 PM EDT
Completed Not applicable Interventional Results available

Comparison of Breath-Enhanced and T-Piece Nebulizers in Children With Acute Asthma

NCT02566902
View directory record Official record
Conditions
Asthma
Interventions
T-Piece Nebulizer, Breath-Enhanced Nebulizer, Albuterol, Pre-Treatment Spirometry Measurement, Post-Treatment Spirometry Measurement
Device · Drug · Procedure
Lead sponsor
Seton Healthcare Family
Other
Eligibility
6 Years to 17 Years
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated May 5, 2021 · Synced Jun 10, 2026, 10:17 PM EDT
Withdrawn Phase 2 Interventional

Repeated High-dose Inhaled Corticosteroids for Asthma

NCT00695604
View directory record Official record
Conditions
Asthma
Interventions
Placebo, Fluticasone
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 50 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 7, 2018 · Synced Jun 10, 2026, 10:17 PM EDT
Completed No phase listed Observational

Acute Asthma Responsiveness and B2 Adrenergic Receptors Polymorphisms

NCT01016444
View directory record Official record
Conditions
Acute Asthma
Interventions
Not listed
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
16 Years to 75 Years
Enrollment
311 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 31, 2021 · Synced Jun 10, 2026, 10:17 PM EDT
Completed No phase listed Observational

Mechanisms of Acute Asthma Exacerbations Through Molecular Analysis of Airway Secretions and Tissues

NCT00603629
View directory record Official record
Conditions
Asthma
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 75 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Jun 10, 2026, 10:17 PM EDT
Completed Not applicable Interventional

Web-Based and Tailored Asthma Management Intervention (Puff City) in Teens With Asthma Attending Urban Clinics

NCT01757002
View directory record Official record
Conditions
Asthma
Interventions
Teens randomized to the experimental arm will receive 4 sessions plus a booster of web-based, tailored asthma management., Teens in the control group will receive generic, web-based asthma education.
Behavioral
Lead sponsor
Henry Ford Health System
Other
Eligibility
13 Years to 19 Years
Enrollment
266 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 8, 2017 · Synced Jun 10, 2026, 10:17 PM EDT
Terminated Phase 4 Interventional Results available

A Pilot Study to Determine the Most Effective Dose of Arformoterol for Treating Acute Asthmatic Patients

NCT00819637
View directory record Official record
Conditions
Acute Asthma
Interventions
arformoterol (RR formoterol), placebo, levalbuterol
Drug
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years to 45 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated May 23, 2023 · Synced Jun 10, 2026, 10:17 PM EDT
Enrolling by invitation No phase listed Observational

Analysis of the Virtual Acute Care at Home Experience

NCT05952999
View directory record Official record
Conditions
Conditions, Infections, Heart Failure, Renal and Urinary Disorders, Diabetes, Hypertension, Fever, Bronchitis, Asthma, Chronic Obstructive Pulmonary Disease (COPD)
Interventions
Digital Care Solution as supportive personalized care, Traditional Hospital Level Care
Other
Lead sponsor
OSF Healthcare System
Other
Eligibility
18 Years and older
Enrollment
9,654 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Peoria, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 16, 2026 · Synced Jun 10, 2026, 10:17 PM EDT
Completed Phase 4 Interventional Results available

Positive Expiratory Pressure for the Treatment of Acute Asthma in Children

NCT02494076
View directory record Official record
Conditions
Asthma
Interventions
EzPAP, Standard Care
Drug · Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
2 Years to 18 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 7, 2017 · Synced Jun 10, 2026, 10:17 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Using Data From a Multisensor Rapid Health Assessment Device to Predict Decompensation in Long COVID (AIDI)

NCT05713266
View directory record Official record
Conditions
COVID-19, Long COVID
Interventions
MouthLabTM
Device
Lead sponsor
Edith Nourse Rogers Memorial Veterans Hospital
Federal
Eligibility
18 Years and older
Enrollment
204 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Bedford, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 15, 2024 · Synced Jun 10, 2026, 10:17 PM EDT
Completed Not applicable Interventional Results available

Procalcitonin Antibiotic Consensus Trial (ProACT)

NCT02130986
View directory record Official record
Conditions
Lower Respiratory Tract Infection (LRTI)
Interventions
Procalcitonin level, Results of procalcitonin (PCT) level to treating clinician, Provide procalcitonin guideline to treating clinician, Telephone Visit
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
1,664 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
13
States / cities
Birmingham, Alabama • Phoenix, Arizona • Orange, California + 8 more
Source: ClinicalTrials.gov public record
Updated Jan 14, 2019 · Synced Jun 10, 2026, 10:17 PM EDT
Terminated Phase 3 Interventional Results available

A Study of Levalbuterol Tartrate HFA Inhalation Aerosol Metered Dose Inhaler (MDI) in Pediatric Subjects

NCT02150499
View directory record Official record
Conditions
Asthma
Interventions
levalbuterol tartrate HFA inhalation aerosol, placebo
Drug
Lead sponsor
Sumitomo Pharma America, Inc.
Industry
Eligibility
Up to 48 Months
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
17
States / cities
St. Petersburg, Florida • DeKalb, Illinois • Nicholasville, Kentucky + 12 more
Source: ClinicalTrials.gov public record
Updated Apr 7, 2016 · Synced Jun 10, 2026, 10:17 PM EDT
Completed No phase listed Observational

Examining Changes in Nasal IL-1 During Acute Asthma Exacerbation in Adolescents

NCT04748055
View directory record Official record
Conditions
Asthma
Interventions
Not listed
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
12 Years to 21 Years
Enrollment
40 participants
Timeline
2021 – 2024
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 9, 2024 · Synced Jun 10, 2026, 10:17 PM EDT
Completed Phase 3 Interventional Results available

Trial of One Versus Two Doses of Dexamethasone for Pediatric Asthma Exacerbation

NCT02725008
View directory record Official record
Conditions
Asthma
Interventions
Dexamethasone, placebo
Drug
Lead sponsor
Geoffrey W Jara-Almonte
Other
Eligibility
18 Months to 20 Years
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Feb 26, 2019 · Synced Jun 10, 2026, 10:17 PM EDT
Completed Phase 4 Interventional Results available

Albuterol Versus Xopenex in Treatment of Acute Asthma in the Emergency Department (ED)

NCT00585039
View directory record Official record
Conditions
Asthma
Interventions
xopenex
Drug
Lead sponsor
Phoenix Children's Hospital
Other
Eligibility
6 Years to 17 Years
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Jun 10, 2026, 10:17 PM EDT
Withdrawn Not applicable Interventional

Initiation of Chronic Asthma Care Regimens in the Pediatric Emergency Department

NCT00388739
View directory record Official record
Conditions
Asthma
Interventions
Intervention: Budesonide, Usual care: albuterol + systemic steroids
Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
1 Year to 18 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 19, 2020 · Synced Jun 10, 2026, 10:17 PM EDT
Withdrawn Not applicable Interventional

Noninvasive Positive Airway Pressure in the Pediatric Emergency Department for the Treatment of Acute Asthma Exacerbations

NCT01497691
View directory record Official record
Conditions
Asthma
Interventions
NIPPV (PALMtop PTV), Volumetric CO2 (NM3), USCOM
Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
2 Years to 18 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 23, 2017 · Synced Jun 10, 2026, 10:17 PM EDT