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ClinicalTrials.gov public records Last synced Oct 30, 2026, 7:01 AM EDT

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Showing 1–24 of 341 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Asystole Clear all
Completed Not applicable Interventional Results available

Optimization of VNS in Epileptic Patients to Induce Cardioprotection

NCT04387435
View directory record Official record
Conditions
Epilepsy, Sudden Cardiac Death
Interventions
A change or titration in the current or frequency settings of the VNS therapy system.
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 6, 2025 · Synced Oct 30, 2026, 7:01 AM EDT
Terminated Not applicable Interventional

Early Coronary Angiography Versus Delayed Coronary Angiography

NCT02387398
View directory record Official record
Conditions
Out-of-Hospital Cardiac Arrest, Hypothermia, Cardiac Arrest
Interventions
Early Angiography
Procedure
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
4
States / cities
Tucson, Arizona • Portland, Maine • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 14, 2022 · Synced Oct 30, 2026, 7:01 AM EDT
Completed Not applicable Interventional

SmartCPR Trial: An Analysis of a Waveform-Based Automated External Defibrillation (AED) Algorithm on Survival From Out-of-Hospital Ventricular Fibrillation

NCT00535106
View directory record Official record
Conditions
Ventricular Fibrillation, Cardiac Arrest
Interventions
Automated external defibrillator (Philips FR2+ AED), SmartCPR, Delayed defibrillation
Device · Other
Lead sponsor
New York City Fire Department
Government
Eligibility
Not listed
Enrollment
900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 19, 2009 · Synced Oct 30, 2026, 7:01 AM EDT
Completed Not applicable Interventional Results available

ECPR for Refractory Out-Of-Hospital Cardiac Arrest

NCT03065647
View directory record Official record
Conditions
Cardiac Arrest, Heart Arrest, Sudden Cardiac Arrest, Cardiopulmonary Arrest, Death, Sudden, Cardiac, Cardiopulmonary Resuscitation, CPR, Extracorporeal Cardiopulmonary Resuscitation, Extracorporeal Membrane Oxygenation
Interventions
Expedited Transport With Mechanical CPR
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 70 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 3, 2021 · Synced Oct 30, 2026, 7:01 AM EDT
Completed No phase listed Observational

Genetic Substudy of the Alternans Before Cardioverter Defibrillator (ABCD) Trial

NCT00583297
View directory record Official record
Conditions
Ventricular Tachycardia, Cardiovascular Diseases, Arrythmia, CVD
Interventions
Not listed
Lead sponsor
CardioDx
Industry
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 22, 2018 · Synced Oct 30, 2026, 7:01 AM EDT
Recruiting Not applicable Interventional

Implanted Loop Recorders for Detection and Management of Arrhythmia With Bruton Tyrosine Kinase Inhibitors

NCT05643235
View directory record Official record
Conditions
Atrial Fibrillation, Supraventricular Arrhythmia, Ventricular Arrhythmias and Cardiac Arrest, Chronic Lymphocytic Leukemia, Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Interventions
Medtronic LINQ-2 Insertable Cardiac Monitor (ILR)
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2030
U.S. locations
1
States / cities
New Hyde Park, New York
Source: ClinicalTrials.gov public record
Updated Sep 18, 2025 · Synced Oct 30, 2026, 7:01 AM EDT
Recruiting Phase 2 Interventional

buRst-supprESsion TO Stop Refractory Status Epilepticus Post-cardiac Arrest

NCT05851391
View directory record Official record
Conditions
Hypoxia-Ischemia, Brain, Heart Arrest, Status Epilepticus, Refractory Status Epilepticus, Seizures, Anoxic-Ischemic Encephalopathy, Anoxia-Ischemia, Cerebral
Interventions
Burst Suppression EEG Target Intravenous Anesthesia, Seizure Suppression EEG Target Intravenous Anesthesia
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Oct 30, 2026, 7:01 AM EDT
Recruiting Not applicable Interventional

Developing and Testing Drone-Delivered AEDs for Cardiac Arrests In Rural America

NCT06229418
View directory record Official record
Conditions
Cardiac Arrest, Sudden Cardiac Arrest
Interventions
DFR AED Pilot Program
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Clemmons, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 1, 2026 · Synced Oct 30, 2026, 7:01 AM EDT
Completed Not applicable Interventional

Targeted Hypothermia Versus Targeted Normothermia After Out-of-hospital Cardiac Arrest

NCT02908308
View directory record Official record
Conditions
Out-of-hospital Cardiac Arrest
Interventions
Targeted temperature management to 33°C, Standard care with early treatment of fever
Procedure
Lead sponsor
Helsingborgs Hospital
Other
Eligibility
18 Years and older
Enrollment
1,900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
2
States / cities
Rochester, New York • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 3, 2023 · Synced Oct 30, 2026, 7:01 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Pharmacokinetics of Advantage Arrest in Children

NCT04186663
View directory record Official record
Conditions
Dental Caries
Interventions
Silver Diamine Fluoride
Drug
Lead sponsor
Advantage Silver Dental Arrest, LLC
Industry
Eligibility
3 Years to 13 Years
Enrollment
59 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 10, 2022 · Synced Oct 30, 2026, 7:01 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

AI-guided Prediction and Treatment of Cardiac Arrest

NCT07452016
View directory record Official record
Conditions
Sudden Cardiac Arrest
Interventions
Machine learning-guided cardiac arrest prediction device
Device
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 16, 2026 · Synced Oct 30, 2026, 7:01 AM EDT
Completed No phase listed Observational

Vfib by ECG or Echo During Cardiac Arrest

NCT04906252
View directory record Official record
Conditions
Cardiac Arrest
Interventions
Echocardiography, Electrocardiogram (ECG)
Diagnostic Test
Lead sponsor
Romolo Gaspari
Other
Eligibility
18 Years and older
Enrollment
813 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
6
States / cities
Hartford, Connecticut • Lebanon, New Hampshire • Stony Brook, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Apr 2, 2025 · Synced Oct 30, 2026, 7:01 AM EDT
Completed Not applicable Interventional Results available

A Digital Flu Intervention for People With Cardiovascular Conditions

NCT04584645
View directory record Official record
Conditions
Cardiovascular Diseases, Atrial Fibrillation, Abnormal Heart Rhythms, Cardiac Arrest, Heart Attack, Myocardial Infarction, Coronary Heart Disease, Heart Failure, Stroke, Cerebrovascular Accident
Interventions
Targeted digital intervention
Other
Lead sponsor
Evidation Health
Industry
Eligibility
18 Years and older
Enrollment
49,138 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
San Mateo, California
Source: ClinicalTrials.gov public record
Updated Jun 21, 2022 · Synced Oct 30, 2026, 7:01 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Immunoinflammatory Response in Post Cardiac Arrest Syndrome (PCAS)

NCT02664831
View directory record Official record
Conditions
Cardiac Arrest, Inflammation, Obesity, Hypoxic Ischemic Encephalopathy (HIE)
Interventions
Not listed
Lead sponsor
MaineHealth
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2028
U.S. locations
1
States / cities
Portland, Maine
Source: ClinicalTrials.gov public record
Updated Jul 18, 2025 · Synced Oct 30, 2026, 7:01 AM EDT
Completed No phase listed Observational

Intestinal Ischemia as a Stimulus for Systemic Inflammatory Response After Cardiac Arrest

NCT01944605
View directory record Official record
Conditions
Cardiac Arrest, Reperfusion Injury
Interventions
Not listed
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 6, 2017 · Synced Oct 30, 2026, 7:01 AM EDT
Completed Phase 2 Interventional Results available

Automated Real-time Feedback on CPR Study

NCT00539539
View directory record Official record
Conditions
Heart Arrest
Interventions
Laerdal Q-CPR /technology
Other
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
1,586 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 25, 2012 · Synced Oct 30, 2026, 7:01 AM EDT
Terminated Not applicable Interventional Results available

Wearable Cardioverter Defibrillator in Hemodialysis Patients (WED-HED) Study

NCT02481206
View directory record Official record
Conditions
Sudden Cardiac Death, Sudden Cardiac Arrest
Interventions
Wearable Cardioverter Defibrillator
Device
Lead sponsor
Zoll Medical Corporation
Industry
Eligibility
50 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
31
States / cities
Corona, California • Downey, California • Escondido, California + 28 more
Source: ClinicalTrials.gov public record
Updated Jan 19, 2021 · Synced Oct 30, 2026, 7:01 AM EDT
Recruiting Phase 1 Interventional

Post-CA Neuroprotection With Magnesium

NCT06455514
View directory record Official record
Conditions
Cardiac Arrest, Return of Spontaneous Circulation
Interventions
Magnesium Sulfate, Saline
Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 85 Years
Enrollment
178 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Oct 30, 2026, 7:01 AM EDT
Completed Phase 2 Interventional Results available

Amantadine to Speed Awakening After Cardiac Arrest

NCT02486211
View directory record Official record
Conditions
Coma, Heart Arrest, Anoxia
Interventions
Amantadine, Placebo
Drug
Lead sponsor
Jon Rittenberger, MD
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
4
States / cities
Portland, Maine • Boston, Massachusetts • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 4, 2019 · Synced Oct 30, 2026, 7:01 AM EDT
Active, not recruiting Not applicable Interventional

Situation Awareness Incorporating Multidisciplinary Teams Reduce Arrests In the Pediatric ICU

NCT06553534
View directory record Official record
Conditions
In-hospital Cardiac Arrest, Cardiopulmonary Resuscitation
Interventions
SAMURAI PICU Bundle
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
Not listed
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
5
States / cities
Chicago, Illinois • Akron, Ohio • Charleston, South Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 16, 2024 · Synced Oct 30, 2026, 7:01 AM EDT
Terminated Phase 2 Interventional Results available

Treatment of Ventricular Tachyarrhythmias Refractory To Shock With Beta Blockers: The SHOCK and BLOCK Trial

NCT00401882
View directory record Official record
Conditions
Cardiac Arrest, Sudden Cardiac Death, Ventricular Fibrillation, Tachycardia, Ventricular
Interventions
Epinephrine, Metoprolol
Drug
Lead sponsor
David Haines, MD
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated May 25, 2017 · Synced Oct 30, 2026, 7:01 AM EDT
Active, not recruiting Not applicable Interventional

Assessment of Combined CCM and ICD Device in HFrEF

NCT05855135
View directory record Official record
Conditions
Heart Failure, Heart Failure With Reduced Ejection Fraction, Implantable Defibrillator User, CCM Therapy, Non-ischemic Cardiomyopathy, Ischemic Cardiomyopathy, Sudden Cardiac Arrest, Arrhythmias, Cardiac, Ventricular Tachycardia, Ventricular Fibrillation
Interventions
OPTIMIZER® Integra CCM-D System (Treatment Arm)
Device
Lead sponsor
Impulse Dynamics
Industry
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
59
States / cities
Glendale, Arizona • Mesa, Arizona • Phoenix, Arizona + 40 more
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Oct 30, 2026, 7:01 AM EDT
Recruiting Not applicable Interventional

COMPARE-VENT Feasibility Pilot Study

NCT07656259
View directory record Official record
Conditions
Respiration Failure, Cardio Vascular Disease, Cardiogenic Pulmonary Oedema, Critical Illness, Mechanical Ventilation, Cardiogenic Shock, Cardiopulmonary
Interventions
Volume Controlled Mode, Pressure Controlled Mode
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 30, 2026, 7:01 AM EDT
Terminated Not applicable Interventional Results available

Pediatric Lead Extractability and Survival Evaluation (PLEASE)

NCT00335036
View directory record Official record
Conditions
Ventricular Tachycardia, Ventricular Fibrillation, Cardiomyopathy, Long QT Syndrome, Congenital Heart Disease
Interventions
ICD lead implant, Thin leads
Device
Lead sponsor
Charles Berul
Other
Eligibility
1 Year to 55 Years
Enrollment
748 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Oct 30, 2026, 7:01 AM EDT