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ClinicalTrials.gov public records Last synced Nov 11, 2026, 6:22 PM EST

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Showing 1–24 of 29 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Atherosclerosis, Endothelial Dysfunction Clear all

Conditions: Healthy, Obesity, Diabetes, Healthy Volunteers, Atherosclerosis
Interventions: MR Imaging Techniques - 1, MR Imaging Techniques - 2, MR Imaging Techniques - 3, MR Imaging Techniques - 4; Device
Lead sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); NIH
Eligibility: 18 Years to 100 Years
Enrollment: 4,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2030
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Atherosclerosis, Endothelial Dysfunction
Interventions: Not listed
Lead sponsor: Emory University; Other
Eligibility: 20 Years to 90 Years
Enrollment: 223 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2010
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Endothelial Dysfunction
Interventions: darapladib, placebo; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 85 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2015
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Endothelial Dysfunction, Insulin Resistance, Metabolic Syndrome, Peripheral Arterial Disease
Interventions: Fish Oil (Omega-3 Fatty Acids); Dietary Supplement
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years to 50 Years
Enrollment: 5 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Carotid Artery Diseases, Atherosclerosis
Interventions: Valsartan, Placebo; Drug
Lead sponsor: Emory University; Other
Eligibility: 21 Years to 80 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2009
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Endothelial Dysfunction
Interventions: Aliskiren, Placebo; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Peripheral Artery Disease, Claudication, Intermittent
Interventions: Passive calf muscle stretching device; Device
Lead sponsor: Penn State University; Other
Eligibility: 40 Years to 85 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: University Park, Pennsylvania

Conditions: Arterial Occlusive Diseases, Atherosclerosis, Coronary Disease, Cytomegalovirus Infections
Interventions: Not listed
Lead sponsor: National Heart, Lung, and Blood Institute (NHLBI); NIH
Eligibility: Not listed
Enrollment: 355 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 1996 – 2000
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Coronary Artery Disease, Atherosclerosis, Inflammation, Endothelial Dysfunction
Interventions: Rilonacept, Placebo; Drug
Lead sponsor: National Heart, Lung, and Blood Institute (NHLBI); NIH
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Coronary Artery Disease, Endothelial Dysfunction
Interventions: darusentan 100 mg; Drug
Lead sponsor: K.Lance Gould; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Coronary Atherosclerosis, Endothelial Dysfunction
Interventions: Blood sampling from the Coronary Sinus and Aorta, Intravascular Ultrasound of the coronary artery.; Other · Procedure
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 85 Years
Enrollment: 166 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2015
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Endothelial Dysfunction
Interventions: atrasentan; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 85 Years
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2008
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Peripheral Arterial Disease
Interventions: atorvastatin, ascorbic acid, Placebo; Drug
Lead sponsor: Boston University; Other
Eligibility: 18 Years and older
Enrollment: 108 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2012
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Coronary Atherosclerosis, Endothelial Dysfunction, Coronary Small Vessel Disease
Interventions: LipiScan/LipiScan IVUS; Device
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 85 Years
Enrollment: 39 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2015
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Hypertension, Aging, Endothelial Dysfunction, Men
Interventions: Blueberry Powder, Placebo Powder; Dietary Supplement
Lead sponsor: Colorado State University; Other
Eligibility: 40 Years to 75 Years · Male only
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2025
U.S. locations: 1
States / cities: Fort Collins, Colorado

Conditions: Menopause, Elevated Blood Pressure, Hypertension, Endothelial Dysfunction
Interventions: Blueberry Powder, Placebo Powder; Dietary Supplement
Lead sponsor: Colorado State University; Other
Eligibility: 45 Years to 65 Years · Female only
Enrollment: 43 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Fort Collins, Colorado

Conditions: HIV, Vascular Diseases, Cardiovascular Diseases, Atherosclerosis, HIV Infections
Interventions: Combination antiretroviral therapy (cART), Pentoxifylline, Placebo; Drug
Lead sponsor: Indiana University; Other
Eligibility: 18 Years and older
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Menopause, Aging
Interventions: KUVAN, Placebo, Cetrotide, Climara, Placebo transdermal patch; Drug
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years to 70 Years · Female only
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Hypertension, Atherosclerosis
Interventions: Not listed
Lead sponsor: National Institute on Aging (NIA); NIH
Eligibility: 50 Years to 90 Years
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2017
U.S. locations: 2
States / cities: Baltimore, Maryland

Conditions: Rheumatoid Arthritis, Endothelial Dysfunction
Interventions: Not listed
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years to 80 Years
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Coronary Arteriosclerosis, Endothelial Dysfunction, Type 2 Diabetes Mellitus
Interventions: Aged Garlic Extract (AGE), Placebo; Dietary Supplement
Lead sponsor: Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center; Other
Eligibility: 30 Years to 75 Years
Enrollment: 88 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Torrance, California

Conditions: Coronary Atherosclerosis, Endothelial Dysfunction, Coronary Small Vessel Disease
Interventions: Optical Coherence Tomography (C7 XR Dragonfly ); Device
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 85 Years
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2015
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Oxidative Stress, Inflammation, Endothelial Dysfunction
Interventions: Coenzyme Q10, Placebo; Dietary Supplement
Lead sponsor: University of Washington; Other
Eligibility: 18 Years to 85 Years
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Estrogen Deficiency, Cardiovascular Disease (CVD), Functional Hypothalamic Amenorrhea, Endothelial Dysfunction
Interventions: 17beta Estradiol, Transdermal placebo patch, Progesterone, Placebo Pill; Drug
Lead sponsor: Cedars-Sinai Medical Center; Other
Eligibility: 18 Years to 60 Years · Female only
Enrollment: 29 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2023
U.S. locations: 1
States / cities: Los Angeles, California

Search by objective public record fields.

New Heart Imaging Techniques to Evaluate Possible Heart Disease

Predictive Medicine Research

Lipoprotein-associated Phospholipase A2 (Lp-PLA2) Progenitor Cells and Coronary Atherosclerosis in Humans

The Effects of Sedentarism on Vascular Function, Inflammation, and Insulin Resistance

Effect of Valsartan on Carotid Artery Disease

The Effect of Tekturna on Endothelial Function and Endothelial Progenitor Cells in Patients With Early Atherosclerosis

Passive Calf Stretching Therapy in Peripheral Artery Disease

Potential Role of CMV in Restenosis Following Angioplasty, in Atherosclerosis, and in Endothelial Dysfunction

Rilonacept to Improve Artery Function in Patients With Atherosclerosis

Darusentan Effect on PET Uptake Heterogeneity

Lp-PLA2 and Coronary Atherosclerosis in Humans

Correlation of Endothelial Function and Early Coronary Artery Disease in Humans

Clinical Utility of Endothelial Dysfunction in PAD

Assessment of Coronary Plaque Composition

Wild Blueberries and Cardiovascular Health in Middle-aged/Older Men and Postmenopausal Women

Blueberries for Improving Vascular Endothelial Function in Postmenopausal Women With Elevated Blood Pressure

Pentoxifylline and Combination Antiretroviral Therapy to Improve Blood Vessel Function in HIV-Infected People

Sex Hormones and Atherosclerosis Prevention in Perimenopausal Women

Age-Related Changes in Body Composition

Atherosclerosis in Rheumatoid Arthritis

Effect of Aged Garlic Extract (AGE) on Improving Coronary Atherosclerosis in People With Type 2 Diabetes Mellitus

Assessment of Coronary Plaque Composition Using Optical Coherence Tomography

CoQ10 Biomarker Trial

Atherosclerosis, Immune Mediated Inflammation and Hypoestrogenemia in Young Women