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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Intermittent Claudication, Peripheral Vascular Disease
Interventions
Niacin Extended Release and Lovastatin Tablets
Drug
Lead sponsor
Kos Pharmaceuticals
Industry
Eligibility
40 Years and older
Enrollment
870 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2003
U.S. locations
26
States / cities
Phoenix, Arizona • Scottsdale, Arizona • Palo Alto, California + 22 more
Withdrawn No phase listed Observational Accepts healthy volunteers

Immunomodulatory Effects of PCSK9 Inhibition

NCT05720156
Conditions
Atherosclerotic Cardiovascular Disease, Cardiovascular Diseases, Atherosclerosis, Arterial Inflammation, Vascular Diseases, Vascular Disease, Peripheral, Vascular Calcification, High Cholesterol/Hyperlipidemia, Heart Diseases, Heart Attack, Stroke, Cerebrovascular Accident, Carotid Artery Diseases, Carotid Atherosclerosis, Transient Ischemic Attack
Interventions
99mTc-tilmanocept SPECT/CT scanning
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Atherosclerotic Cardiovascular Disease
Interventions
Alirocumab 150 mg, Inclisiran
Drug
Lead sponsor
Sanofi
Industry
Eligibility
18 Years to 65 Years · Male only
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Bridgewater, New Jersey
Conditions
Peripheral Arterial Disease(PAD)
Interventions
Not listed
Lead sponsor
Louisiana State University Health Sciences Center Shreveport
Other
Eligibility
18 Years and older
Enrollment
85 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Shreveport, Louisiana
Conditions
Peripheral Arterial Disease
Interventions
Text Messages, Phone Calls, Handout
Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
50 Years and older
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Wichita, Kansas
Not listed No phase listed Observational Accepts healthy volunteers

Effects of Plant-Based Diet on Peripheral Arterial Disease

NCT03798938
Conditions
Peripheral Arterial Disease
Interventions
plant-based diet
Other
Lead sponsor
Vascular Institute of Texas
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Alhambra, California
Conditions
Coronary Atherosclerosis
Interventions
Blinded IVUS assessment, Nonblinded IVUS
Device
Lead sponsor
Volcano Corporation
Industry
Eligibility
18 Years and older
Enrollment
195 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Kansas City, Missouri
Conditions
Peripheral Arterial Disease, Peripheral Vascular Diseases
Interventions
SurVeil Drug Coated Balloon, Angioplasty
Device · Procedure
Lead sponsor
SurModics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
3
States / cities
Raleigh, North Carolina • Columbus, Ohio • Kingsport, Tennessee
Completed Not applicable Interventional

Detour2 Continued Access Study

NCT04625660
Conditions
Peripheral Artery Diseases
Interventions
PQ Bypass System
Device
Lead sponsor
Endologix
Industry
Eligibility
18 Years to 90 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
3
States / cities
Old Saybrook, Connecticut • Elk Grove Village, Illinois • Norfolk, Virginia
Completed Phase 2 Interventional Results available

Vitamin D to Improve Endothelial Function in SLE

NCT01911169
Conditions
Atherosclerosis, Systemic Lupus Erythematosus
Interventions
Cholecalciferol
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 80 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Charleston, South Carolina
Conditions
Aortic Aneurysm, Thoracic, Penetrating Ulcer
Interventions
RelayPro
Device
Lead sponsor
Bolton Medical
Industry
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2025
U.S. locations
24
States / cities
Birmingham, Alabama • Phoenix, Arizona • Irvine, California + 17 more
Conditions
Mood Disorders, Hypertension, Overweight and Obesity, Vascular Stiffness, Sleep, Elevated Blood Pressure
Interventions
Cardiovascular Assessments, Actigraphy, Laboratory assessments, Emotional/ Behavioural assessments
Diagnostic Test · Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
Up to 22 Years
Enrollment
37 participants
Timeline
2020 – 2022
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Chronic Total Occlusion, Atherosclerosis, Coronary Artery Disease, Peripheral Artery Disease
Interventions
Roxwood Anchoring Catheters, Acetylsalicylic Acid, Heparin
Device · Drug
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
25 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
11
States / cities
Phoenix, Arizona • Gainesville, Florida • Hobart, Indiana + 8 more
Completed No phase listed Observational Accepts healthy volunteers

Non-Contrast Enhanced Peripheral Magnetic Resonance Angiography

NCT02823444
Conditions
Peripheral Arterial Disease, Intermittent Claudication, Peripheral Vascular Disease
Interventions
Magnetic Resonance Angiography
Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2018
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Prostate Cancer
Interventions
Coronary CT Angiography (CCTA)
Device
Lead sponsor
Indiana University
Other
Eligibility
40 Years and older · Male only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
3
States / cities
Carmel, Indiana • Indianapolis, Indiana
Conditions
Coronary Atherosclerosis, Acute Coronary Syndrome, Percutaneous Coronary Intervention, Endothelial Shear Stress, Arterial Remodeling
Interventions
Not listed
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
506 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Atherosclerosis, Endothelial Function
Interventions
Nebivolol, Atenolol
Drug
Lead sponsor
Emory University
Other
Eligibility
21 Years to 79 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Atlanta, Georgia
Withdrawn No phase listed Observational

Shockwave: Disruption for A Better Fit

NCT05147363
Conditions
Peripheral Arterial Disease
Interventions
Shockwave Intravenous lithotripsy with a Supera stent
Device
Lead sponsor
Cardiovascular Institute of the South Clinical Research Corporation
Other
Eligibility
18 Years and older
Timeline
2020 – 2022
U.S. locations
1
States / cities
Houma, Louisiana
Conditions
Psoriasis, Atherosclerotic Cardiovascular Disease, Obesity, Dyslipidemia, Cardiometabolic Diseases
Interventions
Niagen, Placebo
Dietary Supplement · Other
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
18 Years to 80 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Bethesda, Maryland
Recruiting No phase listed Observational Accepts healthy volunteers

Using Near-Infrared Light to Better Understand Peripheral Artery Disease

NCT07313410
Conditions
Peripheral Artery Disease (PAD)
Interventions
Not listed
Lead sponsor
The University of Texas at Arlington
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
2
States / cities
Arlington, Texas
Completed Phase 3 Interventional Results available

Intensive Glycemic Control and Skeletal Health Study

NCT00324350
Conditions
Atherosclerosis, Cardiovascular Diseases, Hypercholesterolemia, Hypertension, Diabetes Mellitus, Coronary Disease
Interventions
hypoglycemic agents, hydroxymethylglutaryl-CoA Reductase inhibitors, hypertensive agents
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
40 Years to 79 Years
Enrollment
7,287 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2009
U.S. locations
4
States / cities
Minneapolis, Minnesota • Winston-Salem, North Carolina • Cleveland, Ohio + 1 more
Conditions
Congestive Heart Failure
Interventions
CoVa
Device
Lead sponsor
Aventyn, Inc.
Industry
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
Scottsdale, Arizona
Completed Not applicable Interventional Results available

ILUMIEN IV: OPTIMAL Percutaneous Coronary Intervention (PCI)

NCT03507777
Conditions
Coronary Artery Disease, Coronary Stenosis, Atherosclerosis, STEMI, STEMI - ST Elevation Myocardial Infarction, NSTEMI - Non-ST Segment Elevation Myocardial Infarction (MI)
Interventions
Coronary PCI guided by OCT, Coronary PCI guided by Angiography
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
2,487 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
42
States / cities
Birmingham, Alabama • Scottsdale, Arizona • Burlingame, California + 37 more
Conditions
Intermittent Claudication
Interventions
Cilostazol 100 mg, PMR 200 mg
Drug
Lead sponsor
Genovate Biotechnology Co., Ltd.,
Industry
Eligibility
18 Years to 45 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Springfield, Missouri