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Showing 1–24 of 1,040 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Atrial Fibrillation Clear all
Completed Not applicable Interventional Results available

Prophylactic Maze to Prevent Atrial Fibrillation in Adult Cardiac Surgery

NCT03604432
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
propylactic maze
Device
Lead sponsor
Corewell Health West
Other
Eligibility
70 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Grand Rapids, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 6, 2023 · Synced Sep 10, 2026, 3:29 AM EDT
Completed Phase 4 Interventional

Ablation vs Amiodarone for Treatment of AFib in Patients With CHF and an ICD

NCT00729911
View directory record Official record
Conditions
Heart Failure
Interventions
Atrial Fibrillation ablation, Amiodarone
Procedure · Drug
Lead sponsor
Texas Cardiac Arrhythmia Research Foundation
Other
Eligibility
18 Years and older
Enrollment
203 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Apr 9, 2019 · Synced Sep 10, 2026, 3:29 AM EDT
Completed Phase 3 Interventional Results available

Atrial Fibrillation Clopidogrel Trial With Irbesartan for Prevention of Vascular Events (ACTIVE A)

NCT00249873
View directory record Official record
Conditions
Atrial Fibrillation, Vascular Risk
Interventions
clopidogrel (SR25990C), placebo
Drug
Lead sponsor
Sanofi
Industry
Eligibility
18 Years and older
Enrollment
7,554 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2009
U.S. locations
1
States / cities
Bridgewater, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 14, 2015 · Synced Sep 10, 2026, 3:29 AM EDT
Terminated Phase 3 Interventional Results available

Colchicine to Prevent Post-Pericardiotomy Syndrome and Atrial Fibrillation

NCT02177266
View directory record Official record
Conditions
Atrial Fibrillation, Post-pericardiotomy Syndrome, Constriction
Interventions
Colchicine, Placebo
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
40 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 20, 2017 · Synced Sep 10, 2026, 3:29 AM EDT
Recruiting Not applicable Interventional

Use of 4D-ICE in Conjunction With TEE for Left Atrial Appendage Closure

NCT06061757
View directory record Official record
Conditions
Atrial Fibrillation, Stroke
Interventions
Imaging guidance with TEE and ICE for Left atrial appendage closure
Device
Lead sponsor
Kansas City Heart Rhythm Research Foundation
Other
Eligibility
18 Years to 80 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Overland Park, Kansas
Source: ClinicalTrials.gov public record
Updated Aug 27, 2025 · Synced Sep 10, 2026, 3:29 AM EDT
Completed No phase listed Observational

Effects of Chronic Antihypertensive Therapy on Clinical Outcomes in Septic Shock

NCT02876341
View directory record Official record
Conditions
Atrial Fibrillation, Septic Shock
Interventions
Not listed
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
133 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 12, 2017 · Synced Sep 10, 2026, 3:29 AM EDT
Completed Not applicable Interventional

A Study of the TactiFlex SE Catheter and Volt PFA Generator in Subjects With PAF:

NCT06676072
View directory record Official record
Conditions
Atrial Fibrillation (AF), Atrial Arrhythmia, Paroxysmal AF, Drug Refractory Paroxysmal Atrial Fibrillation
Interventions
PFA Ablation catheter
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
188 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
29
States / cities
Scottsdale, Arizona • Little Rock, Arkansas • Stanford, California + 24 more
Source: ClinicalTrials.gov public record
Updated May 31, 2026 · Synced Sep 10, 2026, 3:29 AM EDT
Enrolling by invitation Not applicable Interventional

Optimizing Stroke Prophylaxis of Acute Atrial Fibrillation With an Electronic Clinical Decision Support Tool

NCT05341986
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Clinical Decision Support (CDS) tool
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 19, 2025 · Synced Sep 10, 2026, 3:29 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Evaluation of the Accuracy and Precision of the INRatio® Prothrombin Time (PT) Monitoring System With New INRatio Test Strip Designed for Low Sample Volume and Heparin Insensitivity

NCT01037270
View directory record Official record
Conditions
Pulmonary Embolism, Atrial Fibrillation, Deep Vein Thrombosis
Interventions
Not listed
Lead sponsor
Abbott RDx Cardiometabolic
Other
Eligibility
18 Years and older
Enrollment
271 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
4
States / cities
Loma Linda, California • Sacramento, California • San Diego, California + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 10, 2013 · Synced Sep 10, 2026, 3:29 AM EDT
Completed No phase listed Observational Results available

Comparison of Intracardiac Echocardiography and Transesophageal Echocardiography

NCT02213666
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Flutter
Interventions
Intracardiac Imaging
Device
Lead sponsor
Elad Anter
Other
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 2, 2017 · Synced Sep 10, 2026, 3:29 AM EDT
Completed Phase 3 Interventional Results available

THERMOCOOL® SMARTTOUCH™ Catheter for the Treatment of Symptomatic Paroxysmal Atrial Fibrillation CONTINUED ACCESS

NCT01639495
View directory record Official record
Conditions
Drug Refractory Symptomatic Paroxysmal Atrial Fibrillation
Interventions
THERMOCOOL® SMARTTOUCH™ Catheter
Device
Lead sponsor
Biosense Webster, Inc.
Industry
Eligibility
18 Years and older
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
20
States / cities
Birmingham, Alabama • Stanford, California • Orlando, Florida + 16 more
Source: ClinicalTrials.gov public record
Updated May 14, 2018 · Synced Sep 10, 2026, 3:29 AM EDT
Recruiting Phase 3 Interventional

Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)

NCT05712200
View directory record Official record
Conditions
Atrial Fibrillation (AF)
Interventions
Abelacimab, Placebo
Biological · Drug
Lead sponsor
Anthos Therapeutics, Inc.
Industry
Eligibility
65 Years and older
Enrollment
2,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
174
States / cities
Birmingham, Alabama • Mobile, Alabama • Gilbert, Arizona + 143 more
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Sep 10, 2026, 3:29 AM EDT
Recruiting Phase 4 Interventional

Stellate Ganglion Block

NCT06271707
View directory record Official record
Conditions
Esophagectomy, Pneumonectomy, Lobectomy
Interventions
0.5% bupivacaine, Saline
Drug · Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 85 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 9, 2026 · Synced Sep 10, 2026, 3:29 AM EDT
Active, not recruiting Not applicable Interventional

RESOLVE-AF: Clinical Evaluation of the Ablacath™ Mapping Catheter and Ablamap® System Utilizing Electrographic Flow (EGF) Mapping to Resolve Extra-PV Sources of Atrial Fibrillation and Guide Ablation Therapy.

NCT05883631
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Fibrillation, Persistent, Atrial Fibrillation Paroxysmal, Arrhythmia, Arrhythmias, Cardiac, Atrial Flutter, Atrial Fibrillation, Paroxysmal or Persistent, Atrial Arrhythmia, Atrial Tachycardia
Interventions
Electrographic Flow (EGF) mapping and ablation of EGF-identified sources of Atrial Fibrillation, Electrographic Flow (EGF) mapping (no ablation)
Device
Lead sponsor
Cortex
Industry
Eligibility
18 Years to 80 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
15
States / cities
Birmingham, Alabama • Phoenix, Arizona • Redwood City, California + 11 more
Source: ClinicalTrials.gov public record
Updated Apr 12, 2025 · Synced Sep 10, 2026, 3:29 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Prevention of Postoperative Atrial Fibrillation

NCT01742039
View directory record Official record
Conditions
Postoperative Atrial Fibrillation
Interventions
Not listed
Lead sponsor
George Washington University
Other
Eligibility
18 Years to 100 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
2
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Oct 12, 2023 · Synced Sep 10, 2026, 3:29 AM EDT
Completed Not applicable Interventional

A Pharmacogenetic Study of Warfarin Dosing, "The COUMA-GEN Study"

NCT00334464
View directory record Official record
Conditions
Atrial Fibrillation, Deep Vein Thrombosis, Pulmonary Embolism
Interventions
Standard of care or genotyping dosing of warfarin dosing
Drug
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Aug 20, 2008 · Synced Sep 10, 2026, 3:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Influence of Sleep Apnea on Risk of Atrial Fibrillation

NCT02576587
View directory record Official record
Conditions
Sleep Apnea, Atrial Fibrillation
Interventions
Continuous Positive Airway Pressure
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
317 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 14, 2018 · Synced Sep 10, 2026, 3:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of the Use of Apple Watch Features for Identification of Cardiac Arrhythmias

NCT03769207
View directory record Official record
Conditions
Atrial Fibrillation, Arrhythmias, Cardiac, Atrial Flutter
Interventions
Ambulatory ECG
Device
Lead sponsor
Apple Inc.
Industry
Eligibility
22 Years and older
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Oct 19, 2020 · Synced Sep 10, 2026, 3:29 AM EDT
Completed No phase listed Observational

Long Term Arrhythmia Risk and Cardiovascular Events in Hematopoietic Stem Cell Transplant

NCT04118530
View directory record Official record
Conditions
Hematopoietic Stem Cell Transplant, Atrial Fibrillation, Atrial Flutter
Interventions
HSCT Patients
Other
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 9, 2024 · Synced Sep 10, 2026, 3:29 AM EDT
Suspended Not applicable Interventional

The CONFORM Pivotal Trial

NCT05147792
View directory record Official record
Conditions
Atrial Fibrillation, Stroke
Interventions
CLAAS, WATCHMAN left atrial appendage closure device / Amulet left atrial appendage occluder
Device
Lead sponsor
Conformal Medical, Inc
Industry
Eligibility
18 Years and older
Enrollment
1,600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2031
U.S. locations
78
States / cities
Birmingham, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 66 more
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 10, 2026, 3:29 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Further Study of AFGen1 Clinical Performance

NCT06335498
View directory record Official record
Conditions
Atrial Fibrillation, Afib, ECG
Interventions
ECG co-measurement, Periodic ECG triggered measurement
Device
Lead sponsor
TriVirum, Inc.
Industry
Eligibility
18 Years to 90 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Gig Harbor, Washington
Source: ClinicalTrials.gov public record
Updated Jun 19, 2024 · Synced Sep 10, 2026, 3:29 AM EDT
Completed Not applicable Interventional

Safety and Efficacy of CryoCor™ Cryoablation for PAF

NCT00231296
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Cardiac CryoCor Cryoablation System, Medical management
Device · Drug
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years to 75 Years
Enrollment
174 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
24
States / cities
Sacramento, California • San Diego, California • San Francisco, California + 21 more
Source: ClinicalTrials.gov public record
Updated May 3, 2017 · Synced Sep 10, 2026, 3:29 AM EDT
Completed Not applicable Interventional

Improved Cardiovascular Risk Reduction to Enhance Rural Primary Care

NCT01983813
View directory record Official record
Conditions
Diabetes Mellitus, Hypertension, Coronary Artery Disease, Atrial Fibrillation, Stroke
Interventions
PHCVRS Intervention, Personal Health Record
Other
Lead sponsor
Korey Kennelty
Other
Eligibility
50 Years and older
Enrollment
302 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
12
States / cities
Akron, Iowa • Belmond, Iowa • Cedar Rapids, Iowa + 9 more
Source: ClinicalTrials.gov public record
Updated Aug 12, 2019 · Synced Sep 10, 2026, 3:29 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Phase 1, Single Ascending Dose Study to Evaluate the Safety, Tolerability, PK, PD, and Comparative Bioavailability of THRV-1268 in Obese Adult Participants

NCT07186946
View directory record Official record
Conditions
Heart Failure
Interventions
THRV-1268, Placebo
Drug
Lead sponsor
Thryv Therapeutics, Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Overland Park, Kansas
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Sep 10, 2026, 3:29 AM EDT