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Showing 1–24 of 32 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Atrial Fibrillation Ablation Procedure Clear all
Not listed Not applicable Interventional

Retracting the Esophagus During AF Ablation

NCT02665442
View directory record Official record
Conditions
Atrial Fibrillation, Esophageal Fistula, Cardiac Arrhythmia
Interventions
Esophageal Stylet - EsoSure
Device
Lead sponsor
Northeast Scientific, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 26, 2016 · Synced Jun 26, 2026, 9:23 AM EDT
Completed No phase listed Observational

Novel Cardiac Signal Processing System

NCT04112433
View directory record Official record
Conditions
Cardiac Arrhythmia
Interventions
PURE EP 2
Device
Lead sponsor
BioSig Technologies, Inc.
Industry
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
3
States / cities
Jacksonville, Florida • Boston, Massachusetts • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Feb 10, 2022 · Synced Jun 26, 2026, 9:23 AM EDT
Terminated Not applicable Interventional

Safety and Efficacy Study of the Combined Ablation Procedure to Treat Paroxysmal Atrial Fibrillation

NCT01103674
View directory record Official record
Conditions
Paroxysmal Atrial Fibrillation
Interventions
Numeris®-AF Guided Coagulation System with VisiTrax®
Device
Lead sponsor
nContact Surgical Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
2
States / cities
Memphis, Tennessee • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Apr 2, 2014 · Synced Jun 26, 2026, 9:23 AM EDT
Completed No phase listed Observational

Short Term Outcomes From Minimally Invasive Surgery for the Treatment of Atrial Fibrillation

NCT00571597
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Not listed
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 85 Years
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 13, 2014 · Synced Jun 26, 2026, 9:23 AM EDT
Recruiting Not applicable Interventional

CellFX® Nanosecond Pulsed Field Ablation (nsPFA)™ Cardiac Surgery Clamp System to Treat Atrial Fibrillation

NCT06959121
View directory record Official record
Conditions
Atrial Fibrillation, Maze Procedure, AF, Ablation
Interventions
CellFX® nsPFA™ Cardiac Surgery System
Device
Lead sponsor
Pulse Biosciences, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
St. Helena, California • Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 11, 2026 · Synced Jun 26, 2026, 9:23 AM EDT
Terminated Not applicable Interventional

Safety and Efficacy Study of The Combined Ablation Procedure To Treat Longstanding Persistent Atrial Fibrillation

NCT01103661
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Numeris®-AF Guided Coagulation System with VisiTrax®
Device
Lead sponsor
nContact Surgical Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
4
States / cities
Indianapolis, Indiana • Memphis, Tennessee • Austin, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 2, 2014 · Synced Jun 26, 2026, 9:23 AM EDT
Terminated Not applicable Interventional

Prospective Clinical Study of the Guidant Microwave Ablation System for the Treatment of PAF in the MIS Procedure

NCT00415558
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Microwave Ablation System
Device
Lead sponsor
Maquet Cardiovascular
Industry
Eligibility
18 Years and older
Timeline
Started 2007
U.S. locations
5
States / cities
Mesa, Arizona • Chico, California • Long Beach, California + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 8, 2009 · Synced Jun 26, 2026, 9:23 AM EDT
Terminated Not applicable Interventional

Prophylactic Pulmonary Vein Isolation Study

NCT00587899
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Pulmonary Vein Isolation
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 13, 2011 · Synced Jun 26, 2026, 9:23 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Cardiovascular Innovation & Research Institute 's NEXUS Registry, the Whole is Greater Than the Parts.

NCT03428048
View directory record Official record
Conditions
Coronary Artery Disease, Atrial Fibrillation (AF)
Interventions
Hybrid procedure, Endocardial ablations, left atrial appendage occlusion
Procedure
Lead sponsor
Cardiovascular Innovation and Research Institute
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2030
U.S. locations
1
States / cities
Glenwood Springs, Colorado
Source: ClinicalTrials.gov public record
Updated May 31, 2020 · Synced Jun 26, 2026, 9:23 AM EDT
Completed Not applicable Interventional Results available

A Fib Clinic of the Future Using KardiaPro Platform for Chronic Care of Patients With AF After Ablation Procedure

NCT03557034
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Kardia Monitoring
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 85 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 14, 2021 · Synced Jun 26, 2026, 9:23 AM EDT
Completed No phase listed Observational

Evaluating the Efficacy and Feasibility of a Novel Wireless ECG Recording System in Monitoring Patients After Atrial Fibrillation Ablation Procedure

NCT01912911
View directory record Official record
Conditions
Persistent Atrial Fibrillation, Paroxysmal Atrial Fibrillation
Interventions
Not listed
Lead sponsor
The Cleveland Clinic
Other
Eligibility
Not listed
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 6, 2014 · Synced Jun 26, 2026, 9:23 AM EDT
Completed Not applicable Interventional Results available

Randomized Evaluation of Redo Ablation Procedures of Atrial Fibrillation With FIRM Guided Procedures

NCT02799043
View directory record Official record
Conditions
Persistent Atrial Fibrillation, Paroxysmal Atrial Fibrillation
Interventions
Standard PVI, FIRM-Guided Procedure and PVI
Procedure
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years to 80 Years
Enrollment
269 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
12
States / cities
Phoenix, Arizona • Ventura, California • Fort Lauderdale, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Jun 26, 2026, 9:23 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Atrial Fibrillation Ablation on Gastric Motility "The AF Gut Study"

NCT01396356
View directory record Official record
Conditions
Atrial Fibrillation Ablation Procedure
Interventions
GI procedures
Procedure
Lead sponsor
Dhanunjaya Lakkireddy, MD, FACC
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jan 9, 2013 · Synced Jun 26, 2026, 9:23 AM EDT
Recruiting Not applicable Interventional

Conquer-AF Protocol for Redo Ablation Procedures in Recurrent Paroxysmal and Persistent Atrial Fibrillation Using the Sphere-9 Catheter and Affera Ablation System (Conquer-AF)

NCT07298473
View directory record Official record
Conditions
Atrial Fibrillation (AF), Persistent Atrial Fibrillation, Paroxysmal Atrial Fibrillation (PAF)
Interventions
Sphere-9 Catheter Ablation
Device
Lead sponsor
Medtronic Cardiac Ablation Solutions
Industry
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
22
States / cities
Birmingham, Alabama • La Jolla, California • Los Angeles, California + 19 more
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Jun 26, 2026, 9:23 AM EDT
Completed Phase 4 Interventional Results available

Use of Dabigatran Etexilate to Prevent Stroke and Thromboembolism

NCT01976507
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Flutter
Interventions
dabigatran etexilate mesylate
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 85 Years
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 11, 2017 · Synced Jun 26, 2026, 9:23 AM EDT
Completed Phase 3 Interventional

Effect of Empirical Left Atrial Appendage Isolation on Long-term Procedure Outcome in Patients With Persistent or Long-standing Persistent Atrial Fibrillation Undergoing Catheter Ablation

NCT01362738
View directory record Official record
Conditions
Persistent Atrial Fibrillation
Interventions
RFCA of PV and extra-PV triggers, LAA isolation along with the conventional ablation strategy
Procedure
Lead sponsor
Texas Cardiac Arrhythmia Research Foundation
Other
Eligibility
18 Years to 75 Years
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
2
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Apr 25, 2017 · Synced Jun 26, 2026, 9:23 AM EDT
Completed Phase 3 Interventional Results available

Safety and Effectiveness Evaluation of the Multi-Electrode Radiofrequency Balloon Catheter for the Treatment of Symptomatic Paroxysmal Atrial Fibrillation

NCT03683030
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Multi-Electrode RF Balloon Catheter
Device
Lead sponsor
Biosense Webster, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
397 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
37
States / cities
Phoenix, Arizona • Los Angeles, California • Newport Beach, California + 32 more
Source: ClinicalTrials.gov public record
Updated Oct 19, 2025 · Synced Jun 26, 2026, 9:23 AM EDT
Completed Not applicable Interventional Results available

CONVERGE - Epi/Endo Ablation For Treatment of Persistent Atrial Fibrillation(AF)

NCT01984346
View directory record Official record
Conditions
Persistent Atrial Fibrillation
Interventions
AtriCure EPi-Sense-AF Guided Coagulation System with VisiTrax, Endocardial RF Catheter ablation using Open Irrigated-tip RF Abaltion Catheter with unidirectional or bidirectional steering
Device
Lead sponsor
AtriCure, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2023
U.S. locations
25
States / cities
Birmingham, Alabama • Huntsville, Alabama • Denver, Colorado + 22 more
Source: ClinicalTrials.gov public record
Updated Nov 12, 2023 · Synced Jun 26, 2026, 9:23 AM EDT
Completed Not applicable Interventional Results available

Assessment of Safety and Effectiveness in Treatment Management of Atrial Fibrillation With the BWI IRE Ablation System

NCT05293639
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Pulse Field Ablation
Device
Lead sponsor
Biosense Webster, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
362 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
30
States / cities
Birmingham, Alabama • Phoenix, Arizona • Jonesboro, Arkansas + 23 more
Source: ClinicalTrials.gov public record
Updated May 24, 2025 · Synced Jun 26, 2026, 9:23 AM EDT
Completed Not applicable Interventional Results available

Evaluating Active Esophageal Cooling During Cardiac Ablation Procedures

NCT04063761
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
esophageal cooling device (Attune Medical, Chicago, IL)
Device
Lead sponsor
Advanced Cooling Therapy, Inc., d/b/a Attune Medical
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jun 16, 2025 · Synced Jun 26, 2026, 9:23 AM EDT
Recruiting Not applicable Interventional

ULTRA-HFIB-Redo: Ultrasound-based Renal Sympathetic Denervation vs Control in Redo Ablation Patients

NCT05988411
View directory record Official record
Conditions
Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation
Interventions
Renal Denervation, Catheter Ablation
Device
Lead sponsor
Vivek Reddy
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
8
States / cities
Jonesboro, Arkansas • San Francisco, California • Thousand Oaks, California + 5 more
Source: ClinicalTrials.gov public record
Updated Dec 14, 2025 · Synced Jun 26, 2026, 9:23 AM EDT
Completed Not applicable Interventional

The Physiological Effects of Pacing on Catheter Ablation Procedures to Treat Atrial Fibrillation

NCT02766712
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Pace During 1st Half of Lesion, Pace During 2nd Half of Lesion
Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 11, 2019 · Synced Jun 26, 2026, 9:23 AM EDT
Completed No phase listed Observational

RHYTHMIA vs CARTO in Redo Ablation Procedures for Atrial Fibrillation

NCT04835844
View directory record Official record
Conditions
Paroxysmal Atrial Fibrillation
Interventions
CARTO, RHYTHMIA
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 90 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Jun 26, 2026, 9:23 AM EDT
Completed Phase 4 Interventional Results available

The Use of Statins Following a Left Atrial Catheter Ablation Procedure to Prevent Atrial Fibrillation

NCT00579098
View directory record Official record
Conditions
Atrial Fibrillation, Arrhythmia, Inflammation, Endothelial Dysfunction
Interventions
Atorvastatin, Placebo
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 90 Years
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 22, 2014 · Synced Jun 26, 2026, 9:23 AM EDT