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ClinicalTrials.gov public records Last synced Oct 20, 2026, 8:22 AM EDT

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Showing 1–24 of 97 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Atrial Flutter Clear all
Recruiting No phase listed Observational

Baseline Atrial Fibrosis Predicts Risk for Post-operative Atrial Fibrillation in Patients Undergoing Cardiac Surgery

NCT05014802
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Arrhythmia, Atrial Flutter, Atrial Tachycardia
Interventions
Not listed
Lead sponsor
Tulane University
Other
Eligibility
40 Years to 120 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
3
States / cities
Covington, Louisiana • New Orleans, Louisiana • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Oct 20, 2026, 8:22 AM EDT
Completed Phase 4 Interventional Results available

Oral vs Intravenous Diltiazem for Rapid Atrial Fibrillation/Flutter Trial

NCT03472495
View directory record Official record
Conditions
Atrial Fibrillation and Flutter
Interventions
Diltiazem Oral Product, Diltiazem Injectable Product
Drug
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 1, 2023 · Synced Oct 20, 2026, 8:22 AM EDT
Completed Phase 4 Interventional Results available

Diltiazem in the Treatment of Atrial Fibrillation or Atrial Flutter With Rapid Ventricular Rate

NCT05661942
View directory record Official record
Conditions
Atrial Fibrillation With Rapid Ventricular Response, Hypotension Drug-Induced
Interventions
Calcium pre-treatment, Placebo
Drug · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Oak Lawn, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 10, 2025 · Synced Oct 20, 2026, 8:22 AM EDT
Terminated No phase listed Observational

Patient Specific Optimized Therapy (PSOT)

NCT03858361
View directory record Official record
Conditions
Data Collection
Interventions
Atrial Flutter Ablation
Device
Lead sponsor
EPD Solutions, A Philips Company
Industry
Eligibility
18 Years and older
Enrollment
566 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Florida City, Florida
Source: ClinicalTrials.gov public record
Updated Jun 8, 2023 · Synced Oct 20, 2026, 8:22 AM EDT
Completed Not applicable Interventional Results available

Multipolar Mapping and Atrial Arrhythmias

NCT02307188
View directory record Official record
Conditions
Atrial Fibrillation or Atrial Flutter
Interventions
Constellation Full Contact Mapping Catheter
Device
Lead sponsor
Angelo Biviano
Other
Eligibility
45 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 16, 2016 · Synced Oct 20, 2026, 8:22 AM EDT
Active, not recruiting Not applicable Interventional

RESOLVE-AF: Clinical Evaluation of the Ablacath™ Mapping Catheter and Ablamap® System Utilizing Electrographic Flow (EGF) Mapping to Resolve Extra-PV Sources of Atrial Fibrillation and Guide Ablation Therapy.

NCT05883631
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Fibrillation, Persistent, Atrial Fibrillation Paroxysmal, Arrhythmia, Arrhythmias, Cardiac, Atrial Flutter, Atrial Fibrillation, Paroxysmal or Persistent, Atrial Arrhythmia, Atrial Tachycardia
Interventions
Electrographic Flow (EGF) mapping and ablation of EGF-identified sources of Atrial Fibrillation, Electrographic Flow (EGF) mapping (no ablation)
Device
Lead sponsor
Cortex
Industry
Eligibility
18 Years to 80 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
15
States / cities
Birmingham, Alabama • Phoenix, Arizona • Redwood City, California + 11 more
Source: ClinicalTrials.gov public record
Updated Apr 13, 2025 · Synced Oct 20, 2026, 8:22 AM EDT
Completed Phase 4 Interventional

A Study to Determine if Identification of Undiagnosed Atrial Fibrillation in People at Least 70 Years of Age Reduces the Risk of Stroke

NCT04126486
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Flutter
Interventions
Zio®XT Monitor
Other
Lead sponsor
Bristol-Myers Squibb
Industry
Eligibility
70 Years and older
Enrollment
11,931 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
176
States / cities
Birmingham, Alabama • Guntersville, Alabama • Montgomery, Alabama + 141 more
Source: ClinicalTrials.gov public record
Updated Jul 12, 2023 · Synced Oct 20, 2026, 8:22 AM EDT
Completed Not applicable Interventional Results available

iPhone Helping Evaluate Atrial Fibrillation Rhythm Through Technology

NCT02731326
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Flutter
Interventions
AliveCor, Behavioral Altering Messaging
Device · Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
264 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 3, 2024 · Synced Oct 20, 2026, 8:22 AM EDT
Completed No phase listed Observational

RF Lesion Monitoring With 8mm IntellaTip MiFi XP

NCT02089672
View directory record Official record
Conditions
Atrial Flutter, Arrhythmia
Interventions
Catheter ablation
Device
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 17, 2015 · Synced Oct 20, 2026, 8:22 AM EDT
Completed No phase listed Observational Results available

FREEZE-AFIB Post-Market Study

NCT05089877
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Flutter
Interventions
Surgical Ablation
Device
Lead sponsor
AtriCure, Inc.
Industry
Eligibility
18 Years to 99 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
6
States / cities
Hartford, Connecticut • New Haven, Connecticut • Evanston, Illinois + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 13, 2025 · Synced Oct 20, 2026, 8:22 AM EDT
Completed Phase 3 Interventional

Clarification of Optimal Anticoagulation Through Genetics

NCT00839657
View directory record Official record
Conditions
Stroke, Venous Thrombosis, Atrial Fibrillation, Atrial Flutter
Interventions
Genotype-guided dosing algorithm for warfarin, Clinical-guided dosing algorithm for warfarin
Behavioral
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
18 Years and older
Enrollment
1,015 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
18
States / cities
Birmingham, Alabama • San Francisco, California • Gainesville, Florida + 15 more
Source: ClinicalTrials.gov public record
Updated Apr 20, 2016 · Synced Oct 20, 2026, 8:22 AM EDT
Completed Phase 3 Interventional Results available

Atrial Flutter Ablation With Contact Therapy Cool Path Ablation System Along With EnSite Velocity Contact System

NCT01401361
View directory record Official record
Conditions
Typical Atrial Flutter
Interventions
Treatment Arm
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
19
States / cities
Birmingham, Alabama • Denver, Colorado • Hartford, Connecticut + 15 more
Source: ClinicalTrials.gov public record
Updated Feb 15, 2019 · Synced Oct 20, 2026, 8:22 AM EDT
Completed No phase listed Observational

Novel Cardiac Signal Processing System

NCT04112433
View directory record Official record
Conditions
Cardiac Arrhythmia
Interventions
PURE EP 2
Device
Lead sponsor
BioSig Technologies, Inc.
Industry
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
3
States / cities
Jacksonville, Florida • Boston, Massachusetts • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Feb 11, 2022 · Synced Oct 20, 2026, 8:22 AM EDT
Recruiting Not applicable Interventional

Left Atrial Imaging Prior to Cardioversion: Leveraging Computed Tomography to Rule Out Thrombus in The Emergency Department (LA CLOTTED)

NCT07002450
View directory record Official record
Conditions
Atrial Fibrillation (AF), Atrial Flutter
Interventions
Cardiac computed tomography angiography, Standard of care management
Diagnostic Test · Other
Lead sponsor
Ottawa Heart Institute Research Corporation
Other
Eligibility
18 Years and older
Enrollment
190 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 20, 2026, 8:22 AM EDT
Completed Phase 3 Interventional

American-Australian-African Trial With Dronedarone in Patients With Atrial Fibrillation or Atrial Flutter for the Maintenance of Sinus Rhythm

NCT00259376
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Flutter
Interventions
Dronedarone (SR33589), placebo
Drug
Lead sponsor
Sanofi
Industry
Eligibility
21 Years and older
Enrollment
629 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2003
U.S. locations
1
States / cities
Bridgewater, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 15, 2010 · Synced Oct 20, 2026, 8:22 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Pulmonary Vein Isolation To Reduce Future Risk Of Atrial Fibrillation In Patients Undergoing Typical Flutter

NCT01710150
View directory record Official record
Conditions
Typical Atrial Flutter, Risk Factors With Future Development of Atrial Flutter
Interventions
CTI ablation alone, CTI ablation and Pulmonary vein isolation (PVI)
Procedure
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 2, 2017 · Synced Oct 20, 2026, 8:22 AM EDT
Completed Phase 3 Interventional Results available

Colchicine For The Prevention Of Perioperative Atrial Fibrillation In Patients Undergoing Thoracic Surgery (COP-AF)

NCT03310125
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Flutter, Myocardial Injury After Non-Cardiac Surgery
Interventions
Active Colchicine, Active Placebo
Drug
Lead sponsor
Population Health Research Institute
Other
Eligibility
55 Years and older
Enrollment
3,209 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
8
States / cities
Weston, Florida • Detroit, Michigan • Stony Brook, New York + 5 more
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Oct 20, 2026, 8:22 AM EDT
Completed Phase 3 Interventional Results available

Apixaban for the Prevention of Stroke in Subjects With Atrial Fibrillation

NCT00412984
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Flutter
Interventions
warfarin, apixaban
Drug
Lead sponsor
Bristol-Myers Squibb
Industry
Eligibility
Not listed
Enrollment
20,976 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
284
States / cities
Birmingham, Alabama • Huntsville, Alabama • Mobile, Alabama + 206 more
Source: ClinicalTrials.gov public record
Updated Jul 3, 2018 · Synced Oct 20, 2026, 8:22 AM EDT
Terminated No phase listed Observational

SHERLOCK 3CG™ Diamond Tip Confirmation System

NCT03288766
View directory record Official record
Conditions
Indication for Peripheral Intravenous Catheterization, Atrial Flutter, Premature Atrial Contraction, Premature Ventricular Contraction, Premature Junctional Contraction, Tachycardia, Atrioventricular Block, Bundle-Branch Block
Interventions
PICC placement with SHERLOCK 3CG™ Diamond TCS with MODUS II software
Procedure
Lead sponsor
C. R. Bard
Industry
Eligibility
21 Years and older
Enrollment
232 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
6
States / cities
Las Vegas, Nevada • Greensboro, North Carolina • Greenville, North Carolina + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 20, 2021 · Synced Oct 20, 2026, 8:22 AM EDT
Completed Phase 3 Interventional

Intravenous Tedisamil in the Rapid Conversion of Atrial Fibrillation or Flutter to Normal Sinus Rhythm in Female Subjects

NCT00126022
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Flutter
Interventions
Tedisamil sesquifumarate
Drug
Lead sponsor
Solvay Pharmaceuticals
Industry
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
Tullahoma, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 16, 2015 · Synced Oct 20, 2026, 8:22 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Get With the Guidelines Atrial Fibrillation Registry

NCT06245187
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Flutter
Interventions
GWTG Atrial Fibrillation program
Other
Lead sponsor
American Heart Association
Other
Eligibility
18 Years to 125 Years
Enrollment
17,198 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2040
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 29, 2025 · Synced Oct 20, 2026, 8:22 AM EDT
Completed Phase 3 Interventional Results available

Rate Control Versus Rhythm Control For Postoperative Atrial Fibrillation

NCT02132767
View directory record Official record
Conditions
Postoperative Atrial Fibrillation
Interventions
Amiodarone, DC-cardioversion, Rate Control
Drug · Procedure
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
523 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
17
States / cities
Los Angeles, California • Atlanta, Georgia • Baltimore, Maryland + 13 more
Source: ClinicalTrials.gov public record
Updated Mar 15, 2019 · Synced Oct 20, 2026, 8:22 AM EDT
Terminated Phase 3 Interventional Results available

Safety and Efficacy of Vanoxerine for the Conversion of Subjects With Recent Onset Atrial Fibrillation or Flutter to Normal Sinus Rhythm

NCT02454283
View directory record Official record
Conditions
Atrial Fibrillation or Flutter
Interventions
Vanoxerine HCl, Placebo
Drug
Lead sponsor
Laguna Pharmaceuticals, Inc.
Industry
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
4
States / cities
Littleton, Colorado • Washington D.C., District of Columbia • Iowa City, Iowa + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 17, 2016 · Synced Oct 20, 2026, 8:22 AM EDT
Recruiting Not applicable Interventional

Intra-abdominal Pressure (IAP) During PFA Treatment of A-fib/ A-Flutter

NCT06876896
View directory record Official record
Conditions
Intra-Abdominal Hypertension
Interventions
Accuryn Foley catheter device
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Oct 20, 2026, 8:22 AM EDT