Clarification of Optimal Anticoagulation Through Genetics
Public ClinicalTrials.gov record NCT00839657. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Multi-Center, Double-Blind Clinical Trial to Evaluate the Use of Clinical Plus Genetic Information to Guide Warfarin Therapy Initiation and Improve Anticoagulation Control for Patients
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Individuals taking warfarin often need frequent dose changes as the international normalized ratio (INR) gets too high or too low which could result in a higher risk of thromboembolism, bleeding and early discontinuation of a highly useful therapy. This study will compare two approaches to warfarin dosing to examine the utility of using genetic information for warfarin dosing.
Study identification
- NCT ID
- NCT00839657
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,015 participants
Conditions and interventions
Conditions
Interventions
- Genotype-guided dosing algorithm for warfarin Behavioral
- Clinical-guided dosing algorithm for warfarin Behavioral
Behavioral
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 2009 (Type not available)
- Primary completion
- Apr 2013 (Actual)
- Completion
- Nov 2013 (Actual)
- Last update posted
- Apr 20, 2016
2009 – 2013
United States locations
- U.S. sites
- 18
- U.S. states
- 16
- U.S. cities
- 18
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35249 | — |
| University of California San Francisco | San Francisco | California | 04143-0131 | — |
| University of Florida | Gainesville | Florida | 32610-0486 | — |
| Georgia Health Sciences University | Augusta | Georgia | 30912 | — |
| Tulane University Health Science Center | New Orleans | Louisiana | 70112 | — |
| University of Maryland School of Medicine | Baltimore | Maryland | 21201 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Mayo Clinic College of Medicine | Rochester | Minnesota | 55905 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Mount Sinai School of Medicine | New York | New York | 10029 | — |
| Montefiore Medical Center | The Bronx | New York | 10467 | — |
| Duke University | Durham | North Carolina | 27710 | — |
| Hospital of the University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Vanderbilt University | Nashville | Tennessee | 37232 | — |
| University of Texas Medical Branch | Galveston | Texas | 77555 | — |
| Intermountain Medical Center | Murray | Utah | 84157-7000 | — |
| University of Utah Health Care | Salt Lake City | Utah | 84132 | — |
| Marshfield Clinical Research Foundation | Marshfield | Wisconsin | 54449 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00839657, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 20, 2016 · Synced Oct 23, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00839657 live on ClinicalTrials.gov.