Study of JK07 in Patients With Chronic Heart Failure
Public ClinicalTrials.gov record NCT06369298. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2 Randomized, Double-blind, Placebo-controlled Study to Assess the Safety and Efficacy of JK07 in Adults With Chronic Heart Failure (RENEU-HF)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a Phase 2, randomized, double-blind, placebo-controlled, multiple dose study to assess the safety, tolerability, and efficacy of JK07 in participants aged 18-85 with heart failure. There will be 2 cohorts in this study: Cohort 1: Heart failure (HF) participants with left ventricular ejection fraction (LVEF) of ≤ 40%. Cohort 2: Heart failure (HF) participants with left ventricular ejection fraction (LVEF) \> 40% and ≤ 65%.
Study identification
- NCT ID
- NCT06369298
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 282 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 28, 2024 (Actual)
- Primary completion
- Oct 31, 2026 (Estimated)
- Completion
- Oct 31, 2026 (Estimated)
- Last update posted
- May 22, 2026
2024 – 2026
United States locations
- U.S. sites
- 51
- U.S. states
- 24
- U.S. cities
- 48
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Site 121 | Alexander City | Alabama | 35010 | — |
| Site 130 | Birmingham | Alabama | 35211 | — |
| Site 139 | Birmingham | Alabama | 35294 | — |
| Site 138 | Huntsville | Alabama | 35801 | — |
| Site 111 | Phoenix | Arizona | 85016 | — |
| Site 127 | Little Rock | Arkansas | 72205 | — |
| Site 128 | Huntington Beach | California | 92648 | — |
| Site 157 | Los Angeles | California | 90033 | — |
| Site 158 | Orange | California | 92868 | — |
| Site 116 | Pasadena | California | 91105 | — |
| Site 129 | Santa Maria | California | 93454 | — |
| Site 102 | Stanford | California | 94305 | — |
| Site 113 | Torrance | California | 90502 | — |
| Site 133 | Vista | California | 92081 | — |
| Site 161 | Coral Gables | Florida | 33134 | — |
| Site 114 | Hialeah | Florida | 33016 | — |
| Site 162 | Miami Lakes | Florida | 33014 | — |
| Site 159 | Naples | Florida | 34104 | — |
| Site 136 | Atlanta | Georgia | 30343 | — |
| Site 143 | Boise | Idaho | 83712 | — |
| Site 160 | Chicago | Illinois | 60611 | — |
| Site 154 | Park Ridge | Illinois | 60068 | — |
| Site 137 | Fort Wayne | Indiana | 46804 | — |
| Site 112 | Indianapolis | Indiana | 46250 | — |
| Site 104 | Covington | Louisiana | 70433 | — |
| Site 118 | Baltimore | Maryland | 21201 | — |
| Site 119 | Boston | Massachusetts | 02114 | — |
| Site 122 | Bloomfield Hills | Michigan | 48304 | — |
| Site 150 | Farmington Hills | Michigan | 48334 | — |
| Site 107 | Rochester | Minnesota | 55905 | — |
| Site 106 | St Louis | Missouri | 63110 | — |
| Site 105 | St Louis | Missouri | 63136 | — |
| Site 144 | Brick | New Jersey | 08724 | — |
| Site 153 | Valhalla | New York | 10595 | — |
| Site 152 | Asheville | North Carolina | 28803 | — |
| Site 109 | Cary | North Carolina | 27518 | — |
| Site 140 | Charlotte | North Carolina | 28204 | — |
| Site 145 | Durham | North Carolina | 27710 | — |
| Site 117 | Cincinnati | Ohio | 45219 | — |
| Site 100 | Cleveland | Ohio | 44195 | — |
| Site 135 | Oklahoma City | Oklahoma | 73135 | — |
| Site 101 | Portland | Oregon | 97239 | — |
| Site 155 | York | Pennsylvania | 17403 | — |
| Site 110 | Dallas | Texas | 75235 | — |
| Site 115 | Dallas | Texas | 75246 | — |
| Site 103 | Houston | Texas | 77030 | — |
| Site 149 | Tomball | Texas | 77375 | — |
| Site 148 | Arlington | Virginia | 22205 | — |
| Site 123 | Falls Church | Virginia | 22042 | — |
| Site 126 | Norfolk | Virginia | 23507 | — |
| Site 163 | Vienna | Virginia | 22182 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 11 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06369298, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 22, 2026 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06369298 live on ClinicalTrials.gov.