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ClinicalTrials.gov public records Last synced Oct 28, 2026, 7:46 AM EDT

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Showing 73–96 of 457 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Augmentation Clear all
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Study of the Safety and Effectiveness of Motiva Implants®

NCT03579901
View directory record Official record
Conditions
Breast Implants
Interventions
Silicone gel-filled breast implants - Motiva Implants® Investigational breast implants
Device
Lead sponsor
Motiva USA LLC
Industry
Eligibility
18 Years to 70 Years · Female only
Enrollment
800 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2033
U.S. locations
27
States / cities
Beverly Hills, California • Santa Monica, California • Westlake Village, California + 20 more
Source: ClinicalTrials.gov public record
Updated Nov 12, 2025 · Synced Oct 28, 2026, 7:46 AM EDT
Completed Phase 3 Interventional

Risperidone vs. Bupropion ER Augmentation of SSRIs in Treatment-Resistant Depression

NCT00179244
View directory record Official record
Conditions
Unipolar Depression
Interventions
Rispridone (drug) and Bupropion ER (drug)
Drug
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 2, 2015 · Synced Oct 28, 2026, 7:46 AM EDT
Withdrawn Phase 2 Interventional

Olanzapine in OUD Patients

NCT05179772
View directory record Official record
Conditions
Opioid Use Disorder
Interventions
Olanzapine
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 1, 2023 · Synced Oct 28, 2026, 7:46 AM EDT
Completed Not applicable Interventional Results available

Raltegravir Augmentation on Persistent Central Nervous System (CNS) Immunoactivation in Treated HIV-1 Patients

NCT00672932
View directory record Official record
Conditions
HIV Infections
Interventions
raltegravir
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 5, 2013 · Synced Oct 28, 2026, 7:46 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

An Eight Week, Double-Blind Efficacy Study of Armodafinil Augmentation to Alleviate Fibromyalgia Fatigue

NCT00678691
View directory record Official record
Conditions
Fibromyalgia, Primary
Interventions
armodafinil, placebo
Drug
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
18 Years to 65 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Dec 18, 2014 · Synced Oct 28, 2026, 7:46 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Pediatric Urology Recovery After Surgery Endeavor (PURSUE)

NCT03245242
View directory record Official record
Conditions
Urologic Surgical Procedures, Urinary Bladder, Neurogenic, Urinary Bladder Diseases
Interventions
Enhanced Recovery after Surgery, Historical usual surgical care
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
4 Years to 25 Years
Enrollment
85 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2026
U.S. locations
7
States / cities
Aurora, Colorado • Chicago, Illinois • St Louis, Missouri + 4 more
Source: ClinicalTrials.gov public record
Updated Dec 26, 2025 · Synced Oct 28, 2026, 7:46 AM EDT
Completed Phase 2 Interventional

Study of SAR447537 (INBRX-101) Compared to Plasma-derived A1PI Therapy in Adults With AATD Emphysema

NCT05856331
View directory record Official record
Conditions
Alpha 1-Antitrypsin Deficiency, Emphysema
Interventions
SAR447537, Zemaira
Drug
Lead sponsor
Sanofi
Industry
Eligibility
18 Years to 80 Years
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
39
States / cities
Birmingham, Alabama • Phoenix, Arizona • Los Angeles, California + 18 more
Source: ClinicalTrials.gov public record
Updated Aug 11, 2025 · Synced Oct 28, 2026, 7:46 AM EDT
Completed Not applicable Interventional Results available

CopiOs® Pericardium Membrane for Localized Alveolar Ridge Augmentation

NCT00889265
View directory record Official record
Conditions
Alveolar Ridge Defect
Interventions
CopiOs Pericardium Membrane
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
4
States / cities
Aurora, Colorado • Indianapolis, Indiana • Houston, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 11, 2014 · Synced Oct 28, 2026, 7:46 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Eye and Carotenoid Augmentation Research and Evaluation (EyeCARE)

NCT06848101
View directory record Official record
Conditions
Vision, Eye Health
Interventions
Carotenoid Group, Control (placebo) group
Dietary Supplement
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
20 Years to 45 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 26, 2025 · Synced Oct 28, 2026, 7:46 AM EDT
Completed Not applicable Interventional Results available

Trial of Low Field Magnetic Stimulation Augmentation of Antidepressant Therapy in Treatment-Resistant Depression

NCT01654796
View directory record Official record
Conditions
Treatment Resistant Depression
Interventions
Low Field Magnetic Stimulation (LFMS), Sham LFMS
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
6
States / cities
Birmingham, Alabama • New Haven, Connecticut • Atlanta, Georgia + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 5, 2017 · Synced Oct 28, 2026, 7:46 AM EDT
Completed No phase listed Observational

Comparing Two Surgical Techniques for Building up the Bone Where a Dental Implant is to be Placed

NCT06871657
View directory record Official record
Conditions
Dental Implant, Sinus Floor Augmentation
Interventions
Sinus lift using osseodensification technique, Sinus lift using the osseocondensation technique
Procedure
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 75 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 13, 2026 · Synced Oct 28, 2026, 7:46 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Immediate Implant Outcomes With and Without Bone Augmentation

NCT05157009
View directory record Official record
Conditions
Tooth Loss, Bone Loss, Alveolar, Dental Diseases, Dental Trauma
Interventions
implant placement
Procedure
Lead sponsor
Verdugo, Fernando, DDS
Individual
Eligibility
20 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
San Gabriel, California
Source: ClinicalTrials.gov public record
Updated Apr 26, 2023 · Synced Oct 28, 2026, 7:46 AM EDT
Completed Early Phase 1 Interventional

Basivertebral Nerve Block During Vertebral Augmentation: An Alternative Approach to Intraprocedural Pain Management

NCT04774029
View directory record Official record
Conditions
Vertebral Compression, Vertebra Compression Fracture, Vertebral Fracture
Interventions
Basivertebral nerve block, Lidocaine induced basivertebral nerve block
Procedure · Drug
Lead sponsor
Northwell Health
Other
Eligibility
50 Years to 100 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Port Jefferson, New York
Source: ClinicalTrials.gov public record
Updated Feb 26, 2021 · Synced Oct 28, 2026, 7:46 AM EDT
Completed Phase 2Phase 3 Interventional

Risperidone Augmentation for PTSD

NCT00215241
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
sertraline and risperidone
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
2
States / cities
Atlanta, Georgia • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 22, 2014 · Synced Oct 28, 2026, 7:46 AM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers

Enhancing Exposure Therapy for Post-traumatic Stress Disorder

NCT01574118
View directory record Official record
Conditions
Chronic Posttraumatic Stress Disorder
Interventions
Revisiting the Trauma memories, Processing the trauma memories, Psychoeducation, Trauma Memory Retrieval Trial, Exposure to video clips related to the patient's trauma, Breathing retraining, Exposure Homework, Compound extinction
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 65 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2020
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Aug 29, 2022 · Synced Oct 28, 2026, 7:46 AM EDT
Completed Not applicable Interventional Results available

Testosterone Antidepressant Augmentation in Women

NCT01783574
View directory record Official record
Conditions
Depression
Interventions
Testosterone, Placebo
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
21 Years to 75 Years · Female only
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
2
States / cities
Boston, Massachusetts • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 6, 2018 · Synced Oct 28, 2026, 7:46 AM EDT
Completed Not applicable Interventional

Preliminary Safety and Effectiveness of SMI-01 as a Tissue Filler

NCT04534660
View directory record Official record
Conditions
Nasolabial Fold, Cheek Augmentation
Interventions
SMI-01
Device
Lead sponsor
Sofregen Medical, Inc.
Industry
Eligibility
22 Years to 65 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
2
States / cities
Encinitas, California • Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 31, 2024 · Synced Oct 28, 2026, 7:46 AM EDT
Completed No phase listed Observational

Registry of Outcomes From AntiReflux Surgery

NCT02923362
View directory record Official record
Conditions
Gastroesophageal Reflux Disease, Hiatal Hernia
Interventions
Laparoscopic Fundoplication, LINX Antireflux
Procedure · Device
Lead sponsor
The Heartburn Foundation
Other
Eligibility
21 Years and older
Enrollment
1,941 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
19
States / cities
Birmingham, Alabama • Mobile, Alabama • Heber Springs, Arkansas + 15 more
Source: ClinicalTrials.gov public record
Updated Aug 7, 2026 · Synced Oct 28, 2026, 7:46 AM EDT
Completed Phase 4 Interventional

Combination Therapy in Patients With Depression

NCT00485862
View directory record Official record
Conditions
Depressive Symptoms
Interventions
Atomoxetine Hydrochloride, Sertraline, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years and older
Enrollment
214 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 13, 2007 · Synced Oct 28, 2026, 7:46 AM EDT
Recruiting No phase listed Observational

BioBrace® Augmentation in Anterior Cruciate Ligament Reconstruction Procedures

NCT06948591
View directory record Official record
Conditions
ACL Tears
Interventions
Anterior cruciate ligament reconstruction with BioBrace® augmentation, Arthroscopic anterior cruciate ligament reconstruction
Device · Procedure
Lead sponsor
CONMED Corporation
Industry
Eligibility
14 Years to 70 Years
Enrollment
500 participants
Timeline
2025 – 2030
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 23, 2026 · Synced Oct 28, 2026, 7:46 AM EDT
Completed Not applicable Interventional

Storytelling Video Intervention for Depressed Primary Care Patients - Pilot Trial

NCT02311725
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
aTAU + sTVi, aTAU + Attention Control Videos
Behavioral
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Dec 4, 2024 · Synced Oct 28, 2026, 7:46 AM EDT
Terminated No phase listed Observational

LINX Reflux Management System or Fundoplication Clinical Study in Patients With Hiatal Hernia >3 cm

NCT04695171
View directory record Official record
Conditions
Hiatal Hernia Large, Gastro Esophageal Reflux, Hiatal Hernia, Hiatal Hernia, Paraesophageal, Reflux, Gastroesophageal, Reflux Acid
Interventions
LINX Reflux Management System, Fundoplication
Device · Procedure
Lead sponsor
Foregut Research Foundation
Other
Eligibility
21 Years and older
Enrollment
336 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
6
States / cities
Los Angeles, California • Lone Tree, Colorado • Coral Springs, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Oct 28, 2026, 7:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Post Market Safety Study and Effectiveness With Evolence in Subjects With Skin Color Types IV-VI

NCT00891774
View directory record Official record
Conditions
Non Therapeutic Body Modification
Interventions
EVOLENCE®
Device
Lead sponsor
Johnson & Johnson Consumer and Personal Products Worldwide
Industry
Eligibility
18 Years and older
Enrollment
172 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
11
States / cities
Los Angeles, California • Rancho Mirage, California • Washington D.C., District of Columbia + 8 more
Source: ClinicalTrials.gov public record
Updated Feb 6, 2019 · Synced Oct 28, 2026, 7:46 AM EDT
Not yet recruiting Early Phase 1 Interventional

Radiographic Changes in the Maxillary Sinus Following Closed Sinus Augmentation With Leukocyte Platelet Rich Fibrin

NCT07836725
View directory record Official record
Conditions
Partially Edentulous Maxilla
Interventions
Leukocyte Platelet Rich Fibrin
Biological
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 85 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2029
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Sep 23, 2026 · Synced Oct 28, 2026, 7:46 AM EDT