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ClinicalTrials.gov public records Last synced Oct 28, 2026, 11:59 PM EDT

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Showing 145–168 of 457 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Augmentation Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Seri Surgical Scaffold Support of the Lower Pole of the Breast

NCT02016612
View directory record Official record
Conditions
Recurrent Ptosis of the Breast
Interventions
Seri Surgical Scaffold
Device
Lead sponsor
Bengtson Center
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
2
States / cities
Grand Rapids, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 13, 2018 · Synced Oct 28, 2026, 11:59 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Bone Graft Particle Size on Bone Vitality and Volume

NCT04778709
View directory record Official record
Conditions
Bilateral Sinus Pneumatization, Posterior Maxillary Ridge Atrophy Due to Extraction
Interventions
Puros allograft
Device
Lead sponsor
NYU College of Dentistry
Other
Eligibility
25 Years to 65 Years
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 1, 2023 · Synced Oct 28, 2026, 11:59 PM EDT
Completed Phase 4 Interventional

Combination Therapy in Patients With Depression

NCT00485862
View directory record Official record
Conditions
Depressive Symptoms
Interventions
Atomoxetine Hydrochloride, Sertraline, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years and older
Enrollment
214 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 13, 2007 · Synced Oct 28, 2026, 11:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Submerged Versus Non-Submerged Healing of Implants Subjected To Contour Augmentation

NCT04559802
View directory record Official record
Conditions
Tooth Loss
Interventions
Transmucosal Technique, Submerged Technique
Procedure
Lead sponsor
Nova Southeastern University
Other
Eligibility
21 Years and older
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Davie, Florida
Source: ClinicalTrials.gov public record
Updated Feb 20, 2024 · Synced Oct 28, 2026, 11:59 PM EDT
Completed Not applicable Interventional

Augmentation of Exposure Therapy for High Levels of Social Anxiety Using Post-exposure Naps

NCT02325128
View directory record Official record
Conditions
Social Anxiety Disorder, Sleep Laboratory
Interventions
Sleep-enhancement of extinction memory
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 40 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
2
States / cities
Boston, Massachusetts • Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 21, 2018 · Synced Oct 28, 2026, 11:59 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Guided Bone Regeneration With and Without the Use of Intra-marrow Penetrations

NCT06353399
View directory record Official record
Conditions
Ridge Augmentation
Interventions
Intra-marrow penetrations, No Intra-marrow penetrations
Procedure
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Apr 9, 2024 · Synced Oct 28, 2026, 11:59 PM EDT
Completed No phase listed Observational

MRI Evaluation of Integrity Implant for Rotator Cuff Tears

NCT06353893
View directory record Official record
Conditions
Rotator Cuff Tears
Interventions
Anika Integrity Implant System
Device
Lead sponsor
Foundation for Orthopaedic Research and Education
Other
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 28, 2026, 11:59 PM EDT
Withdrawn Phase 4 Interventional

The PRIORi-T Trial--Prospective Randomized Investigation of Radiofrequency Targeted Vertebral Augmentation

NCT01480167
View directory record Official record
Conditions
Painful Osteoporotic Vertebral Compression Fractures (VCF)
Interventions
Vertebral Augmentation (STABILIT), Non-operative Management
Device · Other
Lead sponsor
DFINE Inc.
Industry
Eligibility
21 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2011
U.S. locations
6
States / cities
St Louis, Missouri • Lebanon, New Hampshire • Mineola, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 20, 2017 · Synced Oct 28, 2026, 11:59 PM EDT
Completed Phase 2Phase 3 Interventional

Risperidone Augmentation for PTSD

NCT00215241
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
sertraline and risperidone
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
2
States / cities
Atlanta, Georgia • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 22, 2014 · Synced Oct 28, 2026, 11:59 PM EDT
Completed No phase listed Observational

Bright Light Therapy as Augmentation of Depressive Symptoms on Acute Psychiatric Floor

NCT04385394
View directory record Official record
Conditions
Depression
Interventions
Not listed
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
18 Years to 90 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Oct 28, 2021 · Synced Oct 28, 2026, 11:59 PM EDT
Completed Phase 4 Interventional Results available

Effectiveness of Pimozide in Augmenting the Effects of Clozapine in the Treatment of Schizophrenia

NCT00158223
View directory record Official record
Conditions
Schizophrenia, Psychotic Disorders
Interventions
Pimozide, Placebo
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 65 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
3
States / cities
New York, New York • W. Brentwood, New York
Source: ClinicalTrials.gov public record
Updated Apr 9, 2015 · Synced Oct 28, 2026, 11:59 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Safety and Effectiveness of NATRELLE® 410 Highly Cohesive, Anatomically Shaped, Silicone-filled X-Style and L-Style Breast Implants

NCT01785069
View directory record Official record
Conditions
Breast Augmentation, Breast Reconstruction, Breast Implant Revision
Interventions
Anatomically shaped, silicone-filled breast implants with low projection or extra-full projection
Device
Lead sponsor
Allergan
Industry
Eligibility
18 Years and older · Female only
Enrollment
355 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
29
States / cities
Campbell, California • Palo Alto, California • Pleasanton, California + 23 more
Source: ClinicalTrials.gov public record
Updated Jun 25, 2020 · Synced Oct 28, 2026, 11:59 PM EDT
Active, not recruiting Not applicable Interventional

Comparison of Methods of Pulmonary Blood Flow Augmentation in Neonates: Shunt Versus Stent (The COMPASS Trial)

NCT05268094
View directory record Official record
Conditions
Congenital Heart Disease in Children
Interventions
Ductal Arterial Stent, Systemic-to-Pulmonary Artery Shunt
Device · Procedure
Lead sponsor
Carelon Research
Other
Eligibility
1 Day to 30 Days
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
23
States / cities
Birmingham, Alabama • Phoenix, Arizona • Los Angeles, California + 20 more
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Oct 28, 2026, 11:59 PM EDT
Terminated Phase 3 Interventional Results available

Stage 1 Study of ARALAST NP and GLASSIA in A1PI Deficiency

NCT02722304
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease, Alpha1-antitrypsin Deficiency
Interventions
ARALAST NP 60 mg/kg, ARALAST NP 120 mg/kg, GLASSIA 60 mg/kg, GLASSIA 120 mg/kg, Human Albumin 2%
Biological
Lead sponsor
Baxalta now part of Shire
Industry
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
14
States / cities
Peoria, Arizona • Newport Beach, California • Kissimmee, Florida + 11 more
Source: ClinicalTrials.gov public record
Updated May 13, 2021 · Synced Oct 28, 2026, 11:59 PM EDT
Completed Phase 4 Interventional

Topiramate Augmentation in the Treatment of Obsessive-Compulsive Disorder

NCT00211744
View directory record Official record
Conditions
Obsessive-compulsive Disorder
Interventions
topiramate
Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 30, 2018 · Synced Oct 28, 2026, 11:59 PM EDT
Not yet recruiting Not applicable Interventional

Mindfulness-based Neurofeedback to Reduce Negative Thinking in CHARMS Adolescents

NCT06901232
View directory record Official record
Conditions
Repetitive Negative Thinking, Serious Mental Illness Symptoms
Interventions
Mindfulness Training, Active mindfulness-based neurofeedback (Active mbNF), Sham mindfulness-based neurofeedback
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
14 Years to 21 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Oct 28, 2026, 11:59 PM EDT
Terminated Not applicable Interventional Results available

KAVIAR Study - Kyphoplasty And Vertebroplasty In the Augmentation and Restoration of Vertebral Body Compression Fractures

NCT00323609
View directory record Official record
Conditions
Vertebral Body Compression Fractures
Interventions
Vertebroplasty, Kyphoplasty
Procedure
Lead sponsor
Medtronic Spine LLC
Industry
Eligibility
21 Years and older
Enrollment
404 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
25
States / cities
Scottsdale, Arizona • San Jose, California • Torrance, California + 22 more
Source: ClinicalTrials.gov public record
Updated Jan 2, 2018 · Synced Oct 28, 2026, 11:59 PM EDT
Completed Phase 4 Interventional Results available

Quetiapine Augmentation for Treatment-resistant PTSD

NCT00292370
View directory record Official record
Conditions
Combat Disorders, Stress Disorders, Post-Traumatic
Interventions
Open Label (OL) Paroxetine, Placebo, Quetiapine
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 75 Years
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
3
States / cities
Birmingham, Alabama • Tuscaloosa, Alabama • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 16, 2019 · Synced Oct 28, 2026, 11:59 PM EDT
Not listed Phase 4 Interventional

Predictors of Treatment Response to Fluoxetine in PTSD Following a Recent History of War Zone Stress Exposure

NCT00633685
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Combat-related
Interventions
Fluoxetine, Placebo
Drug
Lead sponsor
TEMPVA Research Group, Inc.
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Fort Hood, Texas
Source: ClinicalTrials.gov public record
Updated May 25, 2010 · Synced Oct 28, 2026, 11:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating Error Augmentation for Neurorehabilitation

NCT01574495
View directory record Official record
Conditions
Stroke
Interventions
Error Augmentation
Other
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 24, 2015 · Synced Oct 28, 2026, 11:59 PM EDT
Active, not recruiting Phase 4 Interventional Accepts healthy volunteers

Pharmacological Countermeasures for High Altitude

NCT05300477
View directory record Official record
Conditions
Hypobaric Hypoxia
Interventions
Acetazolamide, Erythropoietin
Drug
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years to 40 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 26, 2025 · Synced Oct 28, 2026, 11:59 PM EDT
Completed Not applicable Interventional

Preliminary Safety and Effectiveness of SMI-01 as a Tissue Filler

NCT04534660
View directory record Official record
Conditions
Nasolabial Fold, Cheek Augmentation
Interventions
SMI-01
Device
Lead sponsor
Sofregen Medical, Inc.
Industry
Eligibility
22 Years to 65 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
2
States / cities
Encinitas, California • Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 31, 2024 · Synced Oct 28, 2026, 11:59 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Bone Tissue Engineering Using Autologous Bone Repair Cell (BRC) Therapy for Sinus Floor Bone Augmentation

NCT00980278
View directory record Official record
Conditions
Tooth Loss
Interventions
Sinus lift augmentation and dental implant, Aastrom BRCs
Procedure · Biological
Lead sponsor
University of Michigan
Other
Eligibility
20 Years to 70 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 23, 2015 · Synced Oct 28, 2026, 11:59 PM EDT
Completed Phase 2 Interventional Results available

Randomized Controlled Study of Donepezil in Fragile X Syndrome

NCT01120626
View directory record Official record
Conditions
Fragile X Syndrome
Interventions
donepezil, sugar pill
Drug
Lead sponsor
Stanford University
Other
Eligibility
12 Years to 29 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Mar 17, 2016 · Synced Oct 28, 2026, 11:59 PM EDT